Cytokine production increases and cytokine clearance decreases in mice with bilateral nephrectomy

Nephrology Dialysis Transplantation

Volumn 27, Issue 12, 2012, Pages 4339-4347

  Andres Hernando, Ana ^a   Dursun, Belda ^b   Altmann, Christopher ^a   Ahuja, Nilesh ^a   He, Zhibin ^a   Bhargava, Rhea ^a   Edelstein, Charles E ^a   Jani, Alkesh ^a   Hoke, Thomas S ^a   Klein, Christina ^c   Faubel, Sarah ^a  

^a UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^b PAMUKKALE UNIVERSITY   (Turkey)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

chemokines; CXCL1; cytokines; IL 6; mononuclear phagocytes

Indexed keywords

CLODRONIC ACID; CXCL1 CHEMOKINE; EOTAXIN; INTERLEUKIN 10; INTERLEUKIN 12P40; INTERLEUKIN 1BETA; INTERLEUKIN 5; INTERLEUKIN 6; MONOCYTE CHEMOTACTIC PROTEIN 1; RANTES; RECOMBINANT CYTOKINE;

ACUTE KIDNEY FAILURE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME METABOLISM; KIDNEY FUNCTION; LIVER; MONONUCLEAR PHAGOCYTE; MOUSE; NEPHRECTOMY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SPLEEN;

ACUTE KIDNEY INJURY; ANIMALS; CYTOKINES; DISEASE MODELS, ANIMAL; MICE; MICE, INBRED C57BL; NEPHRECTOMY;

EID: 84871223664     PISSN: 09310509     EISSN: 14602385     Source Type: Journal    
DOI: 10.1093/ndt/gfs256     Document Type: Article

References (51)

1. Simmons EM, Himmelfarb J, Sezer MT et al. Plasma cytokine levels predict mortality in patients with acute renal failure. Kidney Int 2004; 65: 1357-1365.
2. Hoke TS, Douglas IS, Klein CL et al. Acute renal failure after bilateral nephrectomy is associated with cytokine-mediated pulmonary injury. J Am Soc Nephrol 2007; 18: 155-164.
3. Kielar ML, John R, Bennett M et al. Maladaptive role of IL-6 in ischemic acute renal failure. J Am Soc Nephrol 2005; 16: 3315-3325.
4. Day YJ, Huang L, Ye H et al. Renal ischemia-reperfusion injury and adenosine 2A receptor-mediated tissue protection: role of macrophages. Am J Physiol Renal Physiol 2005; 288: F722-F731.
5. He Z, Lu L, Altmann C et al. Interleukin-18 binding protein transgenic mice are protected against ischemic acute kidney injury. Am J Physiol Renal Physiol 2008; 295: F1414-F1421.
6. Jo SK, Sung SA, Cho WY et al. Macrophages contribute to the initiation of ischaemic acute renal failure in rats. Nephrol Dial Transplant 2006; 21: 1231-1239.
7. Klein CL, Hoke TS, Fang WF et al. Interleukin-6 mediates lung injury following ischemic acute kidney injury or bilateral nephrectomy. Kidney Int 2008; 74: 901-909.
8. Altmann C, Andres-Hernando A, McMahan RH et al. Macrophages mediate lung inflammation in a mouse model of ischemic acute kidney injury. Am J Physiol Renal Physiol 2012; 302: F421-F432.
9. Uchino S, Bellomo R, Goldsmith D et al. An assessment of the RIFLE criteria for acute renal failure in hospitalized patients. Crit Care Med 2006; 34: 1913-1917.
10. Star RA. Treatment of acute renal failure. Kidney Int 1998; 54: 1817-1831.
11. Bates DW, Su L, Yu DT et al. Mortality and costs of acute renal failure associated with amphotericin B therapy. Clin Infect Dis 2001; 32: 686-693.
12. Chertow GM, Lazarus JM, Paganini EP et al. Predictors of mortality and the provision of dialysis in patients with acute tubular necrosis. The Auriculin Anaritide Acute Renal Failure Study Group. J Am Soc Nephrol 1998; 9: 692-698.
13. Lassnigg A, Schmidlin D, Mouhieddine M et al. Minimal changes of serum creatinine predict prognosis in patients after cardiothoracic surgery: a prospective cohort study. J Am Soc Nephrol 2004; 15: 1597-1605.
14. Levy EM, Viscoli CM, Horwitz RI. The effect of acute renal failure on mortality. A cohort analysis. JAMA 1996; 275: 1489-1494.
15. Parikh CR, McSweeney PA, Korular D et al. Renal dysfunction in allogeneic hematopoietic cell transplantation. Kidney Int 2002; 62: 566-573.
16. Chertow GM, Burdick E, Honour M et al. Acute kidney injury, mortality, length of stay, and costs in hospitalized patients. J Am Soc Nephrol 2005; 16: 3365-3370.
17. Waikar SS, Liu KD, Chertow GM. The incidence and prognostic significance of acute kidney injury. Curr Opin Nephrol Hypertens 2007; 16: 227-236.
18. du Cheyron D, Bouchet B, Parienti JJ et al. The attributable mortality of acute renal failure in critically ill patients with liver cirrhosis. Intensive Care Med 2005; 31: 1693-1699.
19. Metnitz PG, Krenn CG, Steltzer H et al. Effect of acute renal failure requiring renal replacement therapy on outcome in critically ill patients. Crit Care Med 2002; 30: 2051-2058.
20. Scheel PJ, Liu M, Rabb H. Uremic lung: new insights into a forgotten condition. Kidney Int 2008; 74: 849-851.
21. Elapavaluru S, Kellum JA. Why do patients die of acute kidney injury? Acta Clin Belg Suppl 2007; 2: 326-331.
22. Kelly KJ. Distant effects of experimental renal ischemia/reperfusion injury. J Am Soc Nephrol 2003; 14: 1549-1558.
23. Park SW, Chen SW, Kim M et al. Cytokines induce small intestine and liver injury after renal ischemia or nephrectomy. Lab Invest 2011; 91: 63-84.
24. Liu M, Liang Y, Chigurupati S et al. Acute kidney injury leads to inflammation and functional changes in the brain. J Am Soc Nephrol 2008; 19: 1360-1370.
25. Ware LB, Matthay MA. The acute respiratory distress syndrome. N Engl J Med 2000; 342: 1334-1349.
26. Bellingan GJ. The pulmonary physician in critical care * 6: the pathogenesis of ALI/ARDS. Thorax 2002; 57: 540-546.
27. Bone RC, Grodzin CJ, Balk RA. Sepsis: a new hypothesis for pathogenesis of the disease process. Chest 1997; 112: 235-243.
28. Andres-Hernando A, Altmann C, Ahuja N et al. Splenectomy exacerbates lung injury after ischemic acute kidney injury in mice. Am J Physiol Renal Physiol 2011; 301: F907-F916.
29. Kielar ML, Rohan Jeyarajah D, Lu CY. The regulation of ischemic acute renal failure by extrarenal organs. Curr Opin Nephrol Hypertens 2002; 11: 451-457.
30. Uchino S, Kellum JA, Bellomo R et al. Acute renal failure in critically ill patients: a multinational, multicenter study. JAMA 2005; 294: 813-818.
31. Angus DC, Linde-Zwirble WT, Lidicker J et al. Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care. Crit Care Med 2001; 29: 1303-1310.
32. Zhang Y, Woodward VK, Shelton JM et al. Ischemia-reperfusion induces G-CSF gene expression by renal medullary thick ascending limb cells in vivo and in vitro. Am J Physiol Renal Physiol 2004; 286: F1193-F1201.
33. Faubel S, Lewis EC, Reznikov L et al. Cisplatin-induced acute renal failure is associated with an increase in the cytokines interleukin (IL)-1beta, IL-18, IL-6, and neutrophil infiltration in the kidney. J Pharmacol Exp Ther 2007; 322: 8-15.
34. Van Rooijen N, Kors N, vd Ende M et al. Depletion and repopulation of macrophages in spleen and liver of rat after intravenous treatment with liposome-encapsulated dichloromethylene diphosphonate. Cell Tissue Res 1990; 260: 215-222.
35. Van Rooijen N, Sanders A. Liposome mediated depletion of macrophages: mechanism of action, preparation of liposomes and applications. J Immunol Methods 1994; 174: 83-93.
36. Van Rooijen N, Sanders A. Kupffer cell depletion by liposome-delivered drugs: comparative activity of intracellular clodronate, propamidine, and ethylenediaminetetraacetic acid. Hepatology 1996; 23: 1239-1243.
37. van Rooijen N, Sanders A. Elimination, blocking, and activation of macrophages: three of a kind? J Leukoc Biol 1997; 62: 702-709.
38. Cho WY, Choi HM, Lee SY et al. The role of Tregs and CD11c(+) macrophages/dendritic cells in ischemic preconditioning of the kidney. Kidney Int 2010; 78: 981-992.
39. Kitamoto K, Machida Y, Uchida J et al. Effects of liposome clodronate on renal leukocyte populations and renal fibrosis in murine obstructive nephropathy. J Pharmacol Sci 2009; 111: 285-292.
40. Rabinovich GA, Riera CM, Iribarren P. Granulocyte-macrophage colony-stimulating factor protects dendritic cells from liposome-encapsulated dichloromethylene diphosphonate-induced apoptosis through a Bcl-2-mediated pathway. Eur J Immunol 1999; 29: 563-570.
41. Sunderkotter C, Nikolic T, Dillon MJ et al. Subpopulations of mouse blood monocytes differ in maturation stage and inflammatory response. J Immunol 2004; 172: 4410-4417.
42. Stenvinkel P, Ketteler M, Johnson RJ et al. IL-10, IL-6, and TNFalpha: central factors in the altered cytokine network of uremia-the good, the bad, and the ugly. Kidney Int 2005; 67: 1216-1233.
43. Brunet P, Capo C, Dellacasagrande J et al. IL-10 synthesis and secretion by peripheral blood mononuclear cells in haemodialysis patients. Nephrol Dial Transplant 1998; 13: 1745-1751.
44. Dennen P, Altmann C, Kaufman J et al. Urine interleukin-6 is an early biomarker of acute kidney injury in children undergoing cardiac surgery. Crit Care 2010; 14: R181.
45. Bocci V. Interleukins. Clinical pharmacokinetics and practical implications. Clin Pharmacokinet 1991; 21: 274-284.
46. Bocci V. Metabolism of protein anticancer agents. Pharmacol Ther 1987; 34: 1-49.
47. Rachmawati H, Beljaars L, Reker-Smit C et al. Pharmacokinetic and biodistribution profile of recombinant human interleukin-10 following intravenous administration in rats with extensive liver fibrosis. Pharm Res 2004; 21: 2072-2078.
48. Castell JV, Geiger T, Gross V et al. Plasma clearance, organ distribution and target cells of interleukin-6/hepatocyte-stimulating factor in the rat. Eur J Biochem 1988; 177: 357-361.
49. Dennen P, Altmann C, Kaufman J et al. Urine interleukin-6 is an early biomarker of acute kidney injury in children undergoing cardiac surgery. Crit Care 2010; 14: R181.
50. Chiu PJ, Radwanski E, Tetiloff G et al. Interleukin-10 pharmacokinetics in intact and nephrectomized mice. Eur Cytokine Netw 1996; 7: 67-69.
51. Liu KD, Altmann C, Smits G et al. Serum interleukin-6 and interleukin-8 are early biomarkers of acute kidney injury and predict prolonged mechanical ventilation in children undergoing cardiac surgery: a case-control study. Crit Care 2009; 13: R104.