Relationship between average leucocyte telomere length and the presence or severity of idiopathic dilated cardiomyopathy in black Africans

European Journal of Heart Failure

Volumn 15, Issue 1, 2013, Pages 54-60

  Raymond, Andrew R ^a   Norton, Gavin R ^a   Sareli, Pinhas ^a   Woodiwiss, Angela J ^a   Brooksbank, Richard L ^a  

^a UNIVERSITY OF THE WITWATERSRAND MEDICAL SCHOOL   (South Africa)

Author keywords

Idiopathic dilated cardiomyopathy; Telomere

Indexed keywords

ADULT; AFRICAN AMERICAN; ALCOHOL CONSUMPTION; ANGIOCARDIOGRAPHY; APOPTOSIS; ARTICLE; CONGESTIVE CARDIOMYOPATHY; CONTROLLED STUDY; DISEASE SEVERITY; ECHOCARDIOGRAPHY; FEMALE; HEART FAILURE; HEART LEFT VENTRICLE EJECTION FRACTION; HUMAN; LEUKOCYTE; MAJOR CLINICAL STUDY; MALE; OXIDATIVE STRESS; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; RISK FACTOR; SMOKING; TELOMERE;

ADULT; AFRICAN CONTINENTAL ANCESTRY GROUP; CARDIOMYOPATHY, DILATED; FEMALE; HUMANS; LEUKOCYTES; MALE; MIDDLE AGED; REAL-TIME POLYMERASE CHAIN REACTION; SEVERITY OF ILLNESS INDEX; STROKE VOLUME; TELOMERE; VENTRICULAR FUNCTION, LEFT;

EID: 84871202946     PISSN: 13889842     EISSN: 18790844     Source Type: Journal    
DOI: 10.1093/eurjhf/hfs147     Document Type: Article

References (29)

1. van der Harst P, van der Steege G, de Boer RA, Voors AA, Hall AS, Mulder MJ, van Gilst WH, van Veldhuisen DJ. Telomere length of circulating leukocytes is decreased in patients with chronic heart failure. J Am Coll Cardiol 2007;49: 1459-1464.
2. Olivieri F, Antonicelli R, Recchioni R, Mariotti S, Marcheselli F, Lisa R, Spazzafumo L, Galeazzi R, Caraceni D, Testa R, Latini R, Procopio AD. Telomere/telomerase system impairment in circulating angiogenic cells of geriatric patients with heart failure. Int J Cardiol 2011; doi:10.1016/j.ijcard. 2011.06.091.
3. van der Harst P, de Boer RA, Samani NJ, Wong LS, Huzen J, Codd V, Hillege HL, Voors AA, van Gilst WH, Jaarsma T, van Veldhuisen DJ. Telomere length and outcome in heart failure. Ann Med 2010;42:36-44.
4. Collerton J, Martin-Ruiz C, Kenny A, Barrass K, von Zglinicki T, Kirkwood T, Keavney B; Newcastle 85+ Core Study Team. Telomere length is associated with left ventricular function in the oldest old: the Newcastle 85+ study. Eur Heart J 2007;28:172-176.
5. Leri A, Franco S, Zacheo A, Barlucchi L, Chimenti S, Limana F, Nadal-Ginard B, Kajstura J, Anversa P, Blasco MA. Ablation of telomerase and telomere loss leads to cardiac dilatation and heart failure associated with pp53 upregulation. EMBO J 2003;22:131-139.
6. Wong LS, Huzen J, de Boer RA, van Gilst WH, van Veldhuisen DJ, van der Harst P. Telomere length of circulating leukocyte subpopulations and buccal cells in patients with ischemic heart failure and their offspring. PLoS ONE 2011;6:e23118.
7. Leri A, Barlucchi L, Limana F, Deptala A, Darzynkiewicz Z, Hintze TH, Kajstura J, Nadal-Ginard B, Anversa P. Telomerase expression and activity are coupled with myocyte proliferation and preservation of telomeric length in the failing heart. Proc Natl Acad Sci USA 2001;98:8626-8631.
8. Chimenti C, Kajstura J, Torella D, Urbanek K, Heleniak H, Colussi C, Di Meglio F, Nadal-Ginard B, Frustaci A, Leri A, Maseri A, Anversa P. Senescence and death of primitive cells and myocytes lead to premature cardiac aging and heart failure. Circ Res 2003;93:604-613.
9. Oh H, Wang SC, Prahash A, Sano M, Moravec CS, Taffet GE, Michael LH, Youker KA, Entman ML, Schneider MD. Telomere attrition and Chk2 activation in human heart failure. Proc Natl Acad Sci USA 2003;100:5378-5383.
10. Moslehi J, DePinho RA, Sahin E. Telomeres and mitochondria in the aging heart. Circ Res 2012;110:1226-1237.
11. Houben JM, Moonen HJ, van Schooten FJ, Hageman GJ. Telomere length assessment: biomarker of chronic oxidative stress? Free Radic Biol Med 2008;44:235-246.
12. Akiyama M, Hideshima T, Hayashi T, Tai YT, Mitsiades CS, Mitsiades N, Chauhan D, Richardson P, Munshi NC, Anderson KC. Nuclear factor-kB p65 mediates tumor necrosis factor-a induced nuclear translocation of telomerase reverse transcriptase protein. Cancer Res 2003;63:18-21.
13. van der Harst P, Wong LS, de Boer RA, Brouilette SW, van der Steege G, Voors AA, Hall AS, Samani NJ, Wikstrand J, van Gilst WH,van Veldhuisen DJ; MERIT-HF Study Group. Possible association between telomere length and renal dysfunction in patients with chronic heart failure. Am J Cardiol 2008;102:207-210.
14. Ogami M, Ikura Y, Ohsawa M, Matsuo S, Kayo S, Yoshimi N, Hai N, Shirai N, Ehara S, Komatsu R, Naruko T, Ueda M. Telomere shortening in human coronary artery diseases. Arterioscler Thromb Vasc Biol 2004;24:546-550.
15. Brouilette S, Singh RK, Thompson JR, Goodall AH, Samani NJ. White cell telomere length and risk of premature myocardial infarction. Arterioscler Thromb Vasc Biol 2003;23:842-846.
16. Zee RY, Michaud SE, Germer S, Ridker PM. Association of shorter mean telomere length with risk of incident myocardial infarction: a prospective, nested case-control approach. Clin Chim Acta 2009;403:139-141.
17. Fitzpatrick AL, Kronmal RA, Gardner JP, Psaty BM, Jenny NS, Tracy RP,Walston J, Kimura M, Aviv A. Leukocyte telomere length and cardiovascular disease in the cardiovascular health study. Am J Epidemiol 2007;165:14-21.
18. Valdes AM, Andrew T, Gardner JP, Kimura M, Oelsner E, Cherkas LF, Aviv A, Spector TD. Obesity, cigarette smoking, and telomere length in women. Lancet 2005;366:662-664.
19. Sliwa K, Skudicky D, Candy G, Wisenbaugh T, Sareli P. Randomised investigation of effects of pentoxifylline on left-ventricular performance in idiopathic dilated cardiomyopathy. Lancet 1998;351:1091-1093.
20. Yücel D, Aydog?du S, Cehreli S, Saydam G, Canatan H, Seneş M, Cig?dem Topkaya B, Nebiog?lu S. Increased oxidative stress in dilated cardiomyopathic heart failure. Clin Chem 1998;44:148-154.
21. Kostin S, Pool L, Elsässer A, Hein S, Drexler HCA, Arnon E, Hayakawa Y, Zimmermann R, Bauer E, Klövekorn W-P, Schaper J. Myocytes die by multiple mechanisms in failing human hearts. Circ Res 2003;92:715-724.
22. Candy GP, Skudicky D, Mueller UK, Woodiwiss AJ, Sliwa K, Luker F, Esser J, Sareli P, Norton GR. Association of left ventricular systolic performance and cavity size with angiotensin-converting enzyme genotype in idiopathic dilated cardiomyopathy. Am J Cardiol 1999;83:740-744.
23. Wisenbaugh T, Katz I, Davis J, Essop R, Skoularigis J, Middlemost S, Rö thlisberger C, Skudicky D, Sareli P. Long-term (3 month) effects of a new betablocker (Nebivolol) on cardiac performance in dilated cardiomyopathy. J Am Coll Cardiol 1993;21:1094-1100.
24. Higuchi R. Rapid and efficient DNA extraction for PCR from cells or blood. Amplifications 1989;2:2-3.
25. Gil ME, Coetzer TL. Real-time quantitative PCR of telomere length. Mol Biotechnol 2004;27:169-172.
26. Cawthon RM. Telomere measurement by quantitative PCR. Nucleic Acids Res 2002;30:e47.
27. Brouilette SW, Moore JS, McMahon AD, Thompson JR, Ford I, Shepherd J, Packard CJ, Samani NJ; West of Scotland Coronary Prevention Study Group. Telomere length, risk of coronary heart disease, and statin treatment in the West of Scotland Primary Prevention Study: a nested case-control study. Lancet 2007;369:107-114.
28. Nordfjäll K, Svenson U, Norrback KF, Adolfsson R, Lenner P, Roos G. The individual blood cell telomere attrition rate is telomere length dependent. PLoS Genet 2009;5:pe1000375.
29. Hemann MT, Strong MA, Hao LY, Greider CW. The shortest telomere, not average telomere length is critical for cell viability and chromosomal stability. Cell 2001;107:67-77.