Endosomes and lysosomes are involved in early steps of Tl(III)-mediated apoptosis in rat pheochromocytoma (PC12) cells

Archives of Toxicology

Volumn 86, Issue 11, 2012, Pages 1667-1680

  Hanzel, Cecilia E ^a   Gubiani, María F Almeira ^a   Verstraeten, Sandra V ^a  

^a UNIVERSIDAD DE BUENOS AIRES   (Argentina)

Author keywords

Acidic compartments; Apoptosis; Caspase; Cathepsin; Endosomes; Lysosomes; Thallium; Toxicity; Transferrin

Indexed keywords

ALOXISTATIN; CASPASE 3; CATHEPSIN B; CATHEPSIN D; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; PEPSTATIN; PROTEIN BID; THALLIUM; TRANSFERRIN;

ACIDIFICATION; ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL COMPARTMENTALIZATION; CELL DAMAGE; CELL LEVEL; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG SCREENING; ENDOSOME; ENZYME ACTIVATION; INCUBATION TIME; LYSOSOME; NONHUMAN; PHEOCHROMOCYTOMA; PHEOCHROMOCYTOMA CELL; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN LOCALIZATION; RAT;

ANIMALS; APOPTOSIS; BH3 INTERACTING DOMAIN DEATH AGONIST PROTEIN; CASPASE 3; CATHEPSIN B; CATHEPSIN D; CELL COMPARTMENTATION; ENDOSOMES; LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEINS; LYSOSOMES; PC12 CELLS; PEPSTATINS; RATS; THALLIUM;

RATTUS;

EID: 84871188211     PISSN: 03405761     EISSN: 14320738     Source Type: Journal    
DOI: 10.1007/s00204-012-0878-3     Document Type: Article

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