Molecular encapsulation of rifampicin as an inclusion complex of hydroxypropyl-β-cyclodextrin: Design; characterization and in vitro dissolution

Colloids and Surfaces B: Biointerfaces

Volumn 103, Issue , 2013, Pages 580-585

  He, Dan ^a   Deng, Ping ^a   Yang, Lin ^b   Tan, Qunyou ^c   Liu, Juan ^a   Yang, Mei ^a   Zhang, Jingqing ^a  

^a CHONGQING MEDICAL UNIVERSITY   (China)

^b Chongqing Institute for Food and Drug Control   (China)

^c THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Characterization; Molecular encapsulation; Rifampicin; Solubility and stability; Stoichiometric calculation

Indexed keywords

ANTI-BACTERIAL ACTIVITY; BACTERIAL INFECTIONS; BINDING CONSTANT; DISSOLUTION RATES; FOURIER; HYDROPHOBIC DRUG; IN-VITRO DISSOLUTION; INCLUSION COMPLEX; INFRARED SPECTRUM; MOLECULAR ENCAPSULATION; MOST PROBABLE CONFIGURATIONS; PHASE SOLUBILITY; RIFAMPICIN; SPECTROSCOPIC METHOD; WEIBULL FUNCTIONS;

CHARACTERIZATION; COMPUTER SIMULATION; DIFFERENTIAL SCANNING CALORIMETRY; DRUG DELIVERY; SOLUBILITY; SPECTROSCOPIC ANALYSIS; WEIBULL DISTRIBUTION;

DISSOLUTION;

2 HYDROXYPROPYL BETA CYCLODEXTRIN; RIFAMPICIN;

ANTIBACTERIAL ACTIVITY; ARTICLE; BINDING AFFINITY; BROTH MACRODILUTION; COMPLEX FORMATION; COMPUTER SIMULATION; DIFFERENTIAL SCANNING CALORIMETRY; DILUTION; DRUG BINDING; DRUG DESIGN; DRUG MANUFACTURE; DRUG SOLUBILITY; DRUG STABILITY; DRUG STRUCTURE; ENCAPSULATION; ENERGY; GIBBS FREE ENERGY; HYDROPHOBICITY; INFRARED SPECTROSCOPY; MOLECULAR ENCAPSULATION; MOLECULAR INCLUSION COMPLEX; MOLECULAR INTERACTION; PHYSICAL PHASE; PRIORITY JOURNAL; SOLID STATE GRINDING METHOD; ULTRAVIOLET SPECTROSCOPY;

ANTI-BACTERIAL AGENTS; BETA-CYCLODEXTRINS; CALORIMETRY, DIFFERENTIAL SCANNING; CHEMISTRY, PHARMACEUTICAL; DRUG STABILITY; ESCHERICHIA COLI; MICROBIAL SENSITIVITY TESTS; PHASE TRANSITION; RIFAMPIN; SOLUBILITY; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; STAPHYLOCOCCUS AUREUS; TIME FACTORS;

BACTERIA (MICROORGANISMS);

EID: 84871152044     PISSN: 09277765     EISSN: 18734367     Source Type: Journal    
DOI: 10.1016/j.colsurfb.2012.10.062     Document Type: Article

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