메뉴 건너뛰기




Volumn 85, Issue 2, 2013, Pages 219-227

Serum hepatitis B surface antigen is correlated with intrahepatic total HBV DNA and cccDNA in treatment-naïve patients with chronic hepatitis B but not in patients with HBV related hepatocellular carcinoma

Author keywords

Chronic hepatitis B; Covalently closed circular DNA; Hepatitis B surface antigen; Hepatitis B virus; Hepatocellular carcinoma; Total HBV DNA

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; COVALENTLY CLOSED CIRCULAR DNA; DEOXYRIBONUCLEASE; HEMOGLOBIN BETA CHAIN; HEPATITIS B SURFACE ANTIGEN; UNCLASSIFIED DRUG; VIRUS DNA;

EID: 84871076917     PISSN: 01466615     EISSN: 10969071     Source Type: Journal    
DOI: 10.1002/jmv.23461     Document Type: Article
Times cited : (30)

References (39)
  • 1
    • 0036315270 scopus 로고    scopus 로고
    • Rebound of hepatitis B virus replication in HepG2 cells after cessation of antiviral treatment
    • Abdelhamed AM, Kelley CM, Miller TG, Furman PA, Isom HC. 2002. Rebound of hepatitis B virus replication in HepG2 cells after cessation of antiviral treatment. J Virol 76:8148-8160.
    • (2002) J Virol , vol.76 , pp. 8148-8160
    • Abdelhamed, A.M.1    Kelley, C.M.2    Miller, T.G.3    Furman, P.A.4    Isom, H.C.5
  • 2
    • 0036109092 scopus 로고    scopus 로고
    • Half-life of the duck hepatitis B Virus covalently closed circular DNA pool in vivo following inhibition of viral replication
    • Addison WR, Walters KA, Wong WW, Wilson JS, Madej D, Jewell LD, Tyrrell DL. 2002. Half-life of the duck hepatitis B Virus covalently closed circular DNA pool in vivo following inhibition of viral replication. J Virol 76:6356-6363.
    • (2002) J Virol , vol.76 , pp. 6356-6363
    • Addison, W.R.1    Walters, K.A.2    Wong, W.W.3    Wilson, J.S.4    Madej, D.5    Jewell, L.D.6    Tyrrell, D.L.7
  • 5
    • 7044260782 scopus 로고    scopus 로고
    • Pathogenesis of hepatitis B virus-related hepatocellular carcinoma: Old and new paradigms
    • Brechot C. 2004. Pathogenesis of hepatitis B virus-related hepatocellular carcinoma: Old and new paradigms. Gastroenterol 127:S56-S61.
    • (2004) Gastroenterol , vol.127
    • Brechot, C.1
  • 6
    • 77949659050 scopus 로고    scopus 로고
    • A new role for an old marker, HBsAg
    • Brunetto MR. 2010. A new role for an old marker, HBsAg. J Hepatol 52:475-477.
    • (2010) J Hepatol , vol.52 , pp. 475-477
    • Brunetto, M.R.1
  • 10
    • 29944436855 scopus 로고    scopus 로고
    • Risk of hepatocellular carcinoma across a biological gradient of serum hepatitis B virus DNA level
    • REVEAL-HBV Study Group.
    • Chen CJ, Yang HI, Su J, Jen CL, You SL, Lu SN, Huang GT, Iloeje UH, REVEAL-HBV Study Group. 2006a. Risk of hepatocellular carcinoma across a biological gradient of serum hepatitis B virus DNA level. J Amer Med Assoc 295:65-73.
    • (2006) J Amer Med Assoc , vol.295 , pp. 65-73
    • Chen, C.J.1    Yang, H.I.2    Su, J.3    Jen, C.L.4    You, S.L.5    Lu, S.N.6    Huang, G.T.7    Iloeje, U.H.8
  • 11
    • 33746675024 scopus 로고    scopus 로고
    • Past HBV viral load as predictor of mortality and morbidity from HCC and chronic liver disease in a prospective study
    • Chen G, Lin W, Shen F, Iloeje UH, London WT, Evans AA. 2006b. Past HBV viral load as predictor of mortality and morbidity from HCC and chronic liver disease in a prospective study. Amer J Gastroenterol 101:1797-1803.
    • (2006) Amer J Gastroenterol , vol.101 , pp. 1797-1803
    • Chen, G.1    Lin, W.2    Shen, F.3    Iloeje, U.H.4    London, W.T.5    Evans, A.A.6
  • 13
    • 1542316127 scopus 로고    scopus 로고
    • Hepatitis B virus infection-natural history and clinical consequences
    • Ganem D, Prince AM. 2004. Hepatitis B virus infection-natural history and clinical consequences. N Engl J Med 350:1118-1129.
    • (2004) N Engl J Med , vol.350 , pp. 1118-1129
    • Ganem, D.1    Prince, A.M.2
  • 16
    • 33748939050 scopus 로고    scopus 로고
    • Intrahepatic levels and replicative activity of covalently closed circular hepatitis B virus DNA in chronically infected patients
    • Laras A, Koskinas J, Dimou E, Kostamena A, Hadziyannis SJ. 2006. Intrahepatic levels and replicative activity of covalently closed circular hepatitis B virus DNA in chronically infected patients. Hepatology 44:694-702.
    • (2006) Hepatology , vol.44 , pp. 694-702
    • Laras, A.1    Koskinas, J.2    Dimou, E.3    Kostamena, A.4    Hadziyannis, S.J.5
  • 17
    • 0030707941 scopus 로고    scopus 로고
    • Hepatitis B virus infection
    • Lee WM. 1997. Hepatitis B virus infection. N Engl J Med 337:1733-1745.
    • (1997) N Engl J Med , vol.337 , pp. 1733-1745
    • Lee, W.M.1
  • 18
    • 84871083383 scopus 로고    scopus 로고
    • Clinical and pathological relationship between quantity of hepatitis B virus covalently closed circular DNA and hepatocellular carcinoma
    • in Chinese).
    • Li T, Ren WH, Xun SF, Zhu YH, Han GQ, Shi J. 2008a. Clinical and pathological relationship between quantity of hepatitis B virus covalently closed circular DNA and hepatocellular carcinoma. Linchuang Jianyan Zazhi 26:188-189; (in Chinese).
    • (2008) Linchuang Jianyan Zazhi , vol.26 , pp. 188-189
    • Li, T.1    Ren, W.H.2    Xun, S.F.3    Zhu, Y.H.4    Han, G.Q.5    Shi, J.6
  • 19
    • 84871070811 scopus 로고    scopus 로고
    • Construction of a 1.2-genome length genotype C HBV construct and study on its expression and replication in HepG2 cells
    • in Chinese).
    • Li WP, Li T, Yan L, Liu BM, Zhuang H. 2008b. Construction of a 1.2-genome length genotype C HBV construct and study on its expression and replication in HepG2 cells. Chinese Hepatol 13:211-215; (in Chinese).
    • (2008) Chinese Hepatol , vol.13 , pp. 211-215
    • Li, W.P.1    Li, T.2    Yan, L.3    Liu, B.M.4    Zhuang, H.5
  • 22
    • 0030776176 scopus 로고    scopus 로고
    • Lack of effect of antiviral therapy in nondividing hepatocyte cultures on the closed circular DNA of woodchuck hepatitis virus
    • Moraleda G, Saputelli J, Aldrich CE, Averett D, Condreay L, Mason WS. 1997. Lack of effect of antiviral therapy in nondividing hepatocyte cultures on the closed circular DNA of woodchuck hepatitis virus. J Virol 71:9392-9399.
    • (1997) J Virol , vol.71 , pp. 9392-9399
    • Moraleda, G.1    Saputelli, J.2    Aldrich, C.E.3    Averett, D.4    Condreay, L.5    Mason, W.S.6
  • 23
    • 0029037074 scopus 로고
    • The covalently closed duplex form of the hepadnavirus genome exists in situ as a heterogeneous population of viral minichromosomes
    • Newbold JE, Xin H, Tencza M, Sherman G, Dean J, Bowden S, Locarnini S. 1995. The covalently closed duplex form of the hepadnavirus genome exists in situ as a heterogeneous population of viral minichromosomes. J Virol 69:3350-3357.
    • (1995) J Virol , vol.69 , pp. 3350-3357
    • Newbold, J.E.1    Xin, H.2    Tencza, M.3    Sherman, G.4    Dean, J.5    Bowden, S.6    Locarnini, S.7
  • 24
    • 68949158334 scopus 로고    scopus 로고
    • Relationship between hepatitis B virus covalently closed circular DNA and HBx protein expression in hepatocellular carcinoma and its significance
    • in Chinese).
    • Pan AH, Huang GY, Chen J, He YL. 2009. Relationship between hepatitis B virus covalently closed circular DNA and HBx protein expression in hepatocellular carcinoma and its significance. Shijie Huaren Xiaohua Zazhi 17:712-715; (in Chinese).
    • (2009) Shijie Huaren Xiaohua Zazhi , vol.17 , pp. 712-715
    • Pan, A.H.1    Huang, G.Y.2    Chen, J.3    He, Y.L.4
  • 25
    • 66149162007 scopus 로고    scopus 로고
    • Benefits and risks of interferon therapy for hepatitis B
    • Perrillo R. 2009. Benefits and risks of interferon therapy for hepatitis B. Hepatology 49:S103-S111.
    • (2009) Hepatology , vol.49
    • Perrillo, R.1
  • 27
    • 1842735646 scopus 로고    scopus 로고
    • Quantitation of hepatitis B virus (HBV) covalently closed circular DNA (cccDNA) in the liver of HBV infected patients by LightCycler real-time PCR
    • Singh M, Dicaire A, Wakil AE, Luscombe C, Sacks SL. 2004. Quantitation of hepatitis B virus (HBV) covalently closed circular DNA (cccDNA) in the liver of HBV infected patients by LightCycler real-time PCR. J Virol Methods 118:159-167.
    • (2004) J Virol Methods , vol.118 , pp. 159-167
    • Singh, M.1    Dicaire, A.2    Wakil, A.E.3    Luscombe, C.4    Sacks, S.L.5
  • 29
    • 67949103443 scopus 로고    scopus 로고
    • Development of hepatocellular carcinoma after seroclearance of hepatitis B surface antigen
    • Tong MJ, Nguyen MO, Tong LT, Blatt LM. 2009. Development of hepatocellular carcinoma after seroclearance of hepatitis B surface antigen. Clin Gastroenterol Hepatol 7:889-893.
    • (2009) Clin Gastroenterol Hepatol , vol.7 , pp. 889-893
    • Tong, M.J.1    Nguyen, M.O.2    Tong, L.T.3    Blatt, L.M.4
  • 30
    • 0029990254 scopus 로고    scopus 로고
    • n-Butyrate, a cell cycle blocker inhibits early amplification of duck hepatitis B virus covalently closed circular DNA after in vitro infection of duck hepatocytes
    • Turin F, Borel C, Benchaib M, Kay A, Jamard C, Guguen-Guillouzo C, Trépo C, Hantz O. 1996. n-Butyrate, a cell cycle blocker inhibits early amplification of duck hepatitis B virus covalently closed circular DNA after in vitro infection of duck hepatocytes. J Virol 70:2691-2696.
    • (1996) J Virol , vol.70 , pp. 2691-2696
    • Turin, F.1    Borel, C.2    Benchaib, M.3    Kay, A.4    Jamard, C.5    Guguen-Guillouzo, C.6    Trépo, C.7    Hantz, O.8
  • 32
    • 4644296081 scopus 로고    scopus 로고
    • Quantitation of covalently closed circular hepatitis B virus DNA in chronic hepatitis B patients
    • Wong DK, Yuen MF, Yuan H, Sum SS, Hui CK, Hall J, Lai CL. 2004. Quantitation of covalently closed circular hepatitis B virus DNA in chronic hepatitis B patients. Hepatology 40:727-737.
    • (2004) Hepatology , vol.40 , pp. 727-737
    • Wong, D.K.1    Yuen, M.F.2    Yuan, H.3    Sum, S.S.4    Hui, C.K.5    Hall, J.6    Lai, C.L.7
  • 33
    • 33748124433 scopus 로고    scopus 로고
    • Quantification of hepatitis B virus covalently closed circular DNA in patient in hepatocellular carcinoma
    • Wong DK, Yuen MF, Poon RT, Yuen JC, Fung J, Lai CL. 2006. Quantification of hepatitis B virus covalently closed circular DNA in patient in hepatocellular carcinoma. J Hepatol 45:553-559.
    • (2006) J Hepatol , vol.45 , pp. 553-559
    • Wong, D.K.1    Yuen, M.F.2    Poon, R.T.3    Yuen, J.C.4    Fung, J.5    Lai, C.L.6
  • 35
    • 0032927750 scopus 로고    scopus 로고
    • Ctyochrome P450 1A1 genetic polymorphisms and risk of hepatocellular carcinoma among chronic hepatitis B carriers
    • Yu MW, Chiu YH, Yang SY, Santella RM, Chern HD, Liaw YF, Chen CJ. 1999. Ctyochrome P450 1A1 genetic polymorphisms and risk of hepatocellular carcinoma among chronic hepatitis B carriers. Br J Cancer 80:598-603.
    • (1999) Br J Cancer , vol.80 , pp. 598-603
    • Yu, M.W.1    Chiu, Y.H.2    Yang, S.Y.3    Santella, R.M.4    Chern, H.D.5    Liaw, Y.F.6    Chen, C.J.7
  • 37
    • 53049107213 scopus 로고    scopus 로고
    • HBsAg seroclearance in chronic hepatitis B in Asian patients: Replicative level and risk of hepatocellular carcinoma
    • Yuen MF, Wong DK, Fung J, Ip P, But D, Hung I, Lau K, Yuen JC, Lai CL. 2008. HBsAg seroclearance in chronic hepatitis B in Asian patients: Replicative level and risk of hepatocellular carcinoma. Gastroenterol 135:1192-1199.
    • (2008) Gastroenterol , vol.135 , pp. 1192-1199
    • Yuen, M.F.1    Wong, D.K.2    Fung, J.3    Ip, P.4    But, D.5    Hung, I.6    Lau, K.7    Yuen, J.C.8    Lai, C.L.9
  • 38
    • 77954605504 scopus 로고    scopus 로고
    • Detection of hepatitis B Virus cccDNA in liver tissues of patients with hepatocellular carcinoma
    • in Chinese).
    • Zhang T, Han T, Gao YT, Chen H, Du Z, Wang YJ. 2007. Detection of hepatitis B Virus cccDNA in liver tissues of patients with hepatocellular carcinoma. Zhonghua Gan Zang Bing Za Zhi 15:232-233; (in Chinese).
    • (2007) Zhonghua Gan Zang Bing Za Zhi , vol.15 , pp. 232-233
    • Zhang, T.1    Han, T.2    Gao, Y.T.3    Chen, H.4    Du, Z.5    Wang, Y.J.6
  • 39
    • 0142027756 scopus 로고    scopus 로고
    • Single-cell analysis of covalently closed circular DNA copy numbers in a hepadnavirus infected liver
    • Zhang YY, Zhang BH, Theele D, Litwin S, Toll E, Summers J. 2003. Single-cell analysis of covalently closed circular DNA copy numbers in a hepadnavirus infected liver. Proc Natl Acad Sci U S A 100:12372-12377.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 12372-12377
    • Zhang, Y.Y.1    Zhang, B.H.2    Theele, D.3    Litwin, S.4    Toll, E.5    Summers, J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.