-
1
-
-
79953295767
-
European cancer mortality predictions for the year 2011
-
Malvezzi M, Arfé A, Bertuccio P, Levi F, La Vecchia C, Negri E. European cancer mortality predictions for the year 2011. Ann Oncol 2011; 22: 947-956.
-
(2011)
Ann Oncol
, vol.22
, pp. 947-956
-
-
Malvezzi, M.1
Arfé, A.2
Bertuccio, P.3
Levi, F.4
la Vecchia, C.5
Negri, E.6
-
2
-
-
0036132096
-
Estimates of the world-wide prevalence of cancer for 25 sites in the adult population
-
Pisani P, Bray F, Parkin DM. Estimates of the world-wide prevalence of cancer for 25 sites in the adult population. Int J Cancer 2002; 97: 72-81.
-
(2002)
Int J Cancer
, vol.97
, pp. 72-81
-
-
Pisani, P.1
Bray, F.2
Parkin, D.M.3
-
3
-
-
0034644185
-
Environmental and heritable factors in the causation of cancer-analyses of cohorts of twins from Sweden, Denmark, and Finland
-
Lichtenstein P, Holm NV, Verkasalo PK, et al. Environmental and heritable factors in the causation of cancer-analyses of cohorts of twins from Sweden, Denmark, and Finland. N Engl J Med 2000; 343: 78-85.
-
(2000)
N Engl J Med
, vol.343
, pp. 78-85
-
-
Lichtenstein, P.1
Holm, N.V.2
Verkasalo, P.K.3
-
4
-
-
79955419172
-
Genetic variants associated with breast-cancer risk: Comprehensive research synopsis, meta-analysis, and epidemiological evidence
-
Zhang B, Beeghly-Fadiel A, Long J, Zheng W. Genetic variants associated with breast-cancer risk: comprehensive research synopsis, meta-analysis, and epidemiological evidence. Lancet Oncol 2011; 12: 477-488.
-
(2011)
Lancet Oncol
, vol.12
, pp. 477-488
-
-
Zhang, B.1
Beeghly-Fadiel, A.2
Long, J.3
Zheng, W.4
-
5
-
-
37549056200
-
The emerging landscape of breast cancer susceptibility
-
Stratton MR, Rahman N. The emerging landscape of breast cancer susceptibility. Nat Genet 2008; 40: 17-22.
-
(2008)
Nat Genet
, vol.40
, pp. 17-22
-
-
Stratton, M.R.1
Rahman, N.2
-
6
-
-
62749148300
-
Hereditary breast and ovarian cancer syndrome
-
ACOG Committee on Practice Bulletins
-
ACOG Committee on Practice Bulletins. Hereditary breast and ovarian cancer syndrome. Gynecol Oncol 2009; 113: 6-11.
-
(2009)
Gynecol Oncol
, vol.113
, pp. 6-11
-
-
-
7
-
-
34250006413
-
Genome-wide association study identifies novel breast cancer susceptibility loci
-
Easton DF, Pooley KA, Dunning AM, et al. Genome-wide association study identifies novel breast cancer susceptibility loci. Nature 2007; 447: 1087-1093.
-
(2007)
Nature
, vol.447
, pp. 1087-1093
-
-
Easton, D.F.1
Pooley, K.A.2
Dunning, A.M.3
-
8
-
-
71449098864
-
Using lifetime risk estimates in personal genomic profiles: Estimation of uncertainty
-
Yang Q, Flanders WD, Moonesinghe R, Ioannidis JP, Guessous I, Khoury MJ. Using lifetime risk estimates in personal genomic profiles: estimation of uncertainty. Am J Hum Genet 2009; 85: 786-800.
-
(2009)
Am J Hum Genet
, vol.85
, pp. 786-800
-
-
Yang, Q.1
Flanders, W.D.2
Moonesinghe, R.3
Ioannidis, J.P.4
Guessous, I.5
Khoury, M.J.6
-
9
-
-
0026649648
-
The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation
-
Momand J, Zambetti GP, Olson DC, George D, Levine AJ. The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation. Cell 1992; 69: 1237-1245.
-
(1992)
Cell
, vol.69
, pp. 1237-1245
-
-
Momand, J.1
Zambetti, G.P.2
Olson, D.C.3
George, D.4
Levine, A.J.5
-
10
-
-
0026740449
-
Amplification of a gene encoding a p53-associated protein in human sarcomas
-
Oliner JD, Kinzler KW, Meltzer PS, George DL, Vogelstein B. Amplification of a gene encoding a p53-associated protein in human sarcomas. Nature 1992; 358: 80-83.
-
(1992)
Nature
, vol.358
, pp. 80-83
-
-
Oliner, J.D.1
Kinzler, K.W.2
Meltzer, P.S.3
George, D.L.4
Vogelstein, B.5
-
11
-
-
0029028354
-
Interaction between the retinoblastoma protein and the oncoprotein MDM2
-
Xiao ZX, Chen J, Levine AJ, et al. Interaction between the retinoblastoma protein and the oncoprotein MDM2. Nature 1995; 375: 694-698.
-
(1995)
Nature
, vol.375
, pp. 694-698
-
-
Xiao, Z.X.1
Chen, J.2
Levine, A.J.3
-
12
-
-
0029028353
-
Stimulation of E2F1/DP1 transcriptional activity by MDM2 oncoprotein
-
Martin K, Trouche D, Hagemeier C, Sorensen TS, La Thangue NB, Kouzarides T. Stimulation of E2F1/DP1 transcriptional activity by MDM2 oncoprotein. Nature 1995; 375: 691-694.
-
(1995)
Nature
, vol.375
, pp. 691-694
-
-
Martin, K.1
Trouche, D.2
Hagemeier, C.3
Sorensen, T.S.4
la Thangue, N.B.5
Kouzarides, T.6
-
13
-
-
21444444598
-
Mdm2 binds to Nbs1 at sites of DNA damage and regulates double strand break repair
-
Alt JR, Bouska A, Fernandez MR, Cerny RL, Xiao H, Eischen CM. Mdm2 binds to Nbs1 at sites of DNA damage and regulates double strand break repair. J Biol Chem 2005; 280: 18771-18781.
-
(2005)
J Biol Chem
, vol.280
, pp. 18771-18781
-
-
Alt, J.R.1
Bouska, A.2
Fernandez, M.R.3
Cerny, R.L.4
Xiao, H.5
Eischen, C.M.6
-
14
-
-
70349437076
-
Partners in life and death
-
p53 and E2f
-
Polager S, Ginsberg D. p53 and E2f: partners in life and death. Nat Rev Cancer 2009; 9: 738-748.
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 738-748
-
-
Polager, S.1
Ginsberg, D.2
-
15
-
-
8844278362
-
A single nucleotide polymorphism in the MDM2 promoter attenuates the p53 tumor suppressor pathway and accelerates tumor formation in humans
-
Bond GL, Hu W, Bond EE, et al. A single nucleotide polymorphism in the MDM2 promoter attenuates the p53 tumor suppressor pathway and accelerates tumor formation in humans. Cell 2004; 119: 591-602.
-
(2004)
Cell
, vol.119
, pp. 591-602
-
-
Bond, G.L.1
Hu, W.2
Bond, E.E.3
-
16
-
-
33847308066
-
A single nucleotide polymorphism in the p53 pathway interacts with gender, environmental stresses and tumor genetics to influence cancer in humans
-
Bond GL, Levine AJ. A single nucleotide polymorphism in the p53 pathway interacts with gender, environmental stresses and tumor genetics to influence cancer in humans. Oncogene 2007; 26: 1317-1323.
-
(2007)
Oncogene
, vol.26
, pp. 1317-1323
-
-
Bond, G.L.1
Levine, A.J.2
-
17
-
-
78651061754
-
ARLTS1, MDM2 and RAD51 gene variations are associated with familial breast cancer
-
Akisik E, Yazici H, Dalay N. ARLTS1, MDM2 and RAD51 gene variations are associated with familial breast cancer. Mol Biol Rep 2011; 38: 343-348.
-
(2011)
Mol Biol Rep
, vol.38
, pp. 343-348
-
-
Akisik, E.1
Yazici, H.2
Dalay, N.3
-
18
-
-
33745783716
-
Association of breast cancer outcome with status of p53 and MDM2 SNP309
-
Boersma BJ, Howe TM, Goodman JE, et al. Association of breast cancer outcome with status of p53 and MDM2 SNP309. J Natl Cancer Inst 2006; 98: 911-919.
-
(2006)
J Natl Cancer Inst
, vol.98
, pp. 911-919
-
-
Boersma, B.J.1
Howe, T.M.2
Goodman, J.E.3
-
19
-
-
33746218700
-
No association of the MDM2 SNP309 polymorphism with risk of breast or ovarian cancer
-
Campbell IG, Eccles DM, Choong DY. No association of the MDM2 SNP309 polymorphism with risk of breast or ovarian cancer. Cancer Lett 2006; 240: 195-197.
-
(2006)
Cancer Lett
, vol.240
, pp. 195-197
-
-
Campbell, I.G.1
Eccles, D.M.2
Choong, D.Y.3
-
20
-
-
33745612767
-
Influence of the MDM2 single nucleotide polymorphism SNP309 on tumour development in BRCA1 mutation carriers
-
Copson ER, White HE, Blaydes JP, Robinson DO, Johnson PW, Eccles DM. Influence of the MDM2 single nucleotide polymorphism SNP309 on tumour development in BRCA1 mutation carriers. BMC Cancer 2006; 6: 80.
-
(2006)
BMC Cancer
, vol.6
, pp. 80
-
-
Copson, E.R.1
White, H.E.2
Blaydes, J.P.3
Robinson, D.O.4
Johnson, P.W.5
Eccles, D.M.6
-
21
-
-
33746239400
-
Polymorphisms in the MDM2 promoter and risk of breast cancer: A case-control analysis in a Chinese population
-
Ma H, Hu Z, Zhai X, et al. Polymorphisms in the MDM2 promoter and risk of breast cancer: a case-control analysis in a Chinese population. Cancer Lett 2006; 240: 261-267.
-
(2006)
Cancer Lett
, vol.240
, pp. 261-267
-
-
Ma, H.1
Hu, Z.2
Zhai, X.3
-
22
-
-
33645459643
-
No association between the MDM2-309 T/G promoter polymorphism and breast cancer in African-Americans or Whites
-
Millikan RC, Heard K, Winkel S, et al. No association between the MDM2-309 T/G promoter polymorphism and breast cancer in African-Americans or Whites. Cancer Epidemiol Biomarkers Prev 2006; 15: 175-177.
-
(2006)
Cancer Epidemiol Biomarkers Prev
, vol.15
, pp. 175-177
-
-
Millikan, R.C.1
Heard, K.2
Winkel, S.3
-
23
-
-
33845944092
-
Lack of association between the MDM2-SNP309 polymorphism and breast cancer risk
-
Petenkaya A, Bozkurt B, Akilli-Ozturk O, Kaya HS, Gur-Dedeoglu B, Yulug IG. Lack of association between the MDM2-SNP309 polymorphism and breast cancer risk. Anticancer Res 2006; 26: 4975-4977.
-
(2006)
Anticancer Res
, vol.26
, pp. 4975-4977
-
-
Petenkaya, A.1
Bozkurt, B.2
Akilli-Ozturk, O.3
Kaya, H.S.4
Gur-Dedeoglu, B.5
Yulug, I.G.6
-
24
-
-
31544482118
-
The single nucleotide polymorphism IVS1+309 in mouse double minute 2 does not affect risk of familial breast cancer
-
Wilkening S, Bermejo JL, Burwinkel B, et al. The single nucleotide polymorphism IVS1+309 in mouse double minute 2 does not affect risk of familial breast cancer. Cancer Res 2006; 66: 646-648.
-
(2006)
Cancer Res
, vol.66
, pp. 646-648
-
-
Wilkening, S.1
Bermejo, J.L.2
Burwinkel, B.3
-
25
-
-
34249982811
-
The p53 Arg72Pro and MDM2-309 polymorphisms and risk of breast cancer in the nurses' health studies
-
Cox DG, Deer D, Guo Q, et al. The p53 Arg72Pro and MDM2-309 polymorphisms and risk of breast cancer in the nurses' health studies. Cancer Causes Control 2007; 18: 621-625.
-
(2007)
Cancer Causes Control
, vol.18
, pp. 621-625
-
-
Cox, D.G.1
Deer, D.2
Guo, Q.3
-
26
-
-
35148876519
-
Do MDM2 SNP309 and TP53 R72P interact in breast cancer susceptibility? A large pooled series from the breast cancer association consortium
-
Schmidt MK, Reincke S, Broeks A, et al. Do MDM2 SNP309 and TP53 R72P interact in breast cancer susceptibility? A large pooled series from the breast cancer association consortium. Cancer Res 2007; 67: 9584-9590.
-
(2007)
Cancer Res
, vol.67
, pp. 9584-9590
-
-
Schmidt, M.K.1
Reincke, S.2
Broeks, A.3
-
27
-
-
34447540243
-
MDM2 SNP309 accelerates familial breast carcinogenesis independently of estrogen signaling
-
Wasielewski M, Nagel JH, Brekelmans C, et al. MDM2 SNP309 accelerates familial breast carcinogenesis independently of estrogen signaling. Breast Cancer Res Treat 2007; 104: 153-157.
-
(2007)
Breast Cancer Res Treat
, vol.104
, pp. 153-157
-
-
Wasielewski, M.1
Nagel, J.H.2
Brekelmans, C.3
-
28
-
-
46249094186
-
MDM2SNP309 does not associate with elevated MDM2 protein expression or breast cancer risk
-
Krekac D, Brozkova K, Knoflickova D, et al. MDM2SNP309 does not associate with elevated MDM2 protein expression or breast cancer risk. Oncology 2008; 74: 84-87.
-
(2008)
Oncology
, vol.74
, pp. 84-87
-
-
Krekac, D.1
Brozkova, K.2
Knoflickova, D.3
-
29
-
-
41849110219
-
MDM2 SNP309 G allele increases risk but the T allele is associated with earlier onset age of sporadic breast cancers in the Chinese population
-
Lum SS, Chua HW, Li H, et al. MDM2 SNP309 G allele increases risk but the T allele is associated with earlier onset age of sporadic breast cancers in the Chinese population. Carcinogenesis 2008; 29: 754-761.
-
(2008)
Carcinogenesis
, vol.29
, pp. 754-761
-
-
Lum, S.S.1
Chua, H.W.2
Li, H.3
-
30
-
-
55349146001
-
MDM2 SNP309 is associated with high grade node positive breast tumours and is in linkage disequilibrium with a novel MDM2 intron 1 polymorphism
-
Paulin FE, O'Neill M, McGregor G, et al. MDM2 SNP309 is associated with high grade node positive breast tumours and is in linkage disequilibrium with a novel MDM2 intron 1 polymorphism. BMC Cancer 2008; 8: 281.
-
(2008)
BMC Cancer
, vol.8
, pp. 281
-
-
Paulin, F.E.1
O'Neill, M.2
McGregor, G.3
-
31
-
-
36549070713
-
Association of polymorphism in MDM-2 and p53 genes with breast cancer risk in Indian women
-
Singh V, Rastogi N, Mathur N, Singh K, Singh MP. Association of polymorphism in MDM-2 and p53 genes with breast cancer risk in Indian women. Ann Epidemiol 2008; 18: 48-57.
-
(2008)
Ann Epidemiol
, vol.18
, pp. 48-57
-
-
Singh, V.1
Rastogi, N.2
Mathur, N.3
Singh, K.4
Singh, M.P.5
-
32
-
-
51649118386
-
MDM2 SNP309 accelerates breast and ovarian carcinogenesis in BRCA1 and BRCA2 carriers of Jewish-Ashkenazi descent
-
Yarden RI, Friedman E, Metsuyanim S, Olender T, Ben-Asher E, Papa MZ. MDM2 SNP309 accelerates breast and ovarian carcinogenesis in BRCA1 and BRCA2 carriers of Jewish-Ashkenazi descent. Breast Cancer Res Treat 2008; 111: 497-504.
-
(2008)
Breast Cancer Res Treat
, vol.111
, pp. 497-504
-
-
Yarden, R.I.1
Friedman, E.2
Metsuyanim, S.3
Olender, T.4
Ben-Asher, E.5
Papa, M.Z.6
-
33
-
-
70349316753
-
The significance of MDM2 SNP309 and p53 Arg72Pro in young women with breast cancer
-
Lång A, Palmeback Wegman P, Wingren S. The significance of MDM2 SNP309 and p53 Arg72Pro in young women with breast cancer. Oncol Rep 2009; 22: 575-579.
-
(2009)
Oncol Rep
, vol.22
, pp. 575-579
-
-
Lång, A.1
Palmeback, W.P.2
Wingren, S.3
-
34
-
-
70349974409
-
The TP53 Arg72Pro and MDM2 309G>T polymorphisms are not associated with breast cancer risk in BRCA1 and BRCA2 mutation carriers
-
Sinilnikova OM, Antoniou AC, Simard J, et al. The TP53 Arg72Pro and MDM2 309G>T polymorphisms are not associated with breast cancer risk in BRCA1 and BRCA2 mutation carriers. Br J Cancer 2009; 101: 1456-1460.
-
(2009)
Br J Cancer
, vol.101
, pp. 1456-1460
-
-
Sinilnikova, O.M.1
Antoniou, A.C.2
Simard, J.3
-
35
-
-
61849084791
-
Results based on 124 cases of breast cancer and 97 controls from Taiwan suggest that the single nucleotide polymorphism (SNP309) in the MDM2 gene promoter is associated with earlier onset and increased risk of breast cancer
-
Sun YF, Leu JD, Chen SM, Lin IF, Lee YJ. Results based on 124 cases of breast cancer and 97 controls from Taiwan suggest that the single nucleotide polymorphism (SNP309) in the MDM2 gene promoter is associated with earlier onset and increased risk of breast cancer. BMC Cancer 2009; 9: 13.
-
(2009)
BMC Cancer
, vol.9
, pp. 13
-
-
Sun, Y.F.1
Leu, J.D.2
Chen, S.M.3
Lin, I.F.4
Lee, Y.J.5
-
36
-
-
79751471610
-
The MDM2 promoter SNP285C/309G haplotype diminishes Sp1 transcription factor binding and reduces risk for breast and ovarian cancer in Caucasians
-
Knappskog S, Bjornslett M, Myklebust LM, et al. The MDM2 promoter SNP285C/309G haplotype diminishes Sp1 transcription factor binding and reduces risk for breast and ovarian cancer in Caucasians. Cancer Cell 2011; 19: 273-282.
-
(2011)
Cancer Cell
, vol.19
, pp. 273-282
-
-
Knappskog, S.1
Bjornslett, M.2
Myklebust, L.M.3
-
37
-
-
0028890628
-
Interobserver reproducibility of the Nottingham modification of the Bloom and Richardson histologic grading scheme for infiltrating ductal carcinoma
-
Frierson HF Jr, Wolber RA, Berean KW, et al. Interobserver reproducibility of the Nottingham modification of the Bloom and Richardson histologic grading scheme for infiltrating ductal carcinoma. Am J Clin Pathol 1995; 103: 195-198.
-
(1995)
Am J Clin Pathol
, vol.103
, pp. 195-198
-
-
Frierson Jr., H.F.1
Wolber, R.A.2
Berean, K.W.3
-
39
-
-
0023339504
-
Molecular analysis and chromosomal mapping of amplified genes isolated from a transformed mouse 3T3 cell line
-
Cahilly-Snyder L, Yang-Feng T, Francke U, George DL. Molecular analysis and chromosomal mapping of amplified genes isolated from a transformed mouse 3T3 cell line. Somat Cell Mol Genet 1987; 13: 235-244.
-
(1987)
Somat Cell Mol Genet
, vol.13
, pp. 235-244
-
-
Cahilly-Snyder, L.1
Yang-Feng, T.2
Francke, U.3
George, D.L.4
-
40
-
-
0025853776
-
Tumorigenic potential associated with enhanced expression of a gene that is amplified in a mouse tumor cell line
-
Fakharzadeh SS, Trusko SP, George DL. Tumorigenic potential associated with enhanced expression of a gene that is amplified in a mouse tumor cell line. EMBO J 1991; 10: 1565-9.
-
(1991)
EMBO J
, vol.10
, pp. 1565-1569
-
-
Fakharzadeh, S.S.1
Trusko, S.P.2
George, D.L.3
-
42
-
-
0028098165
-
Molecular abnormalities of mdm2 and p53 genes in adult soft tissue sarcomas
-
Cordon-Cardo C, Latres E, Drobnjak M, et al. Molecular abnormalities of mdm2 and p53 genes in adult soft tissue sarcomas. Cancer Res 1994; 54: 794-799.
-
(1994)
Cancer Res
, vol.54
, pp. 794-799
-
-
Cordon-Cardo, C.1
Latres, E.2
Drobnjak, M.3
-
43
-
-
1042274013
-
Amplification of the MDM2 gene, but not expression of splice variants of MDM2 MRNA, is associated with prognosis in soft tissue sarcoma
-
Bartel F, Meye A, Würl P, et al. Amplification of the MDM2 gene, but not expression of splice variants of MDM2 MRNA, is associated with prognosis in soft tissue sarcoma. Int J Cancer 2001; 95: 168-175.
-
(2001)
Int J Cancer
, vol.95
, pp. 168-175
-
-
Bartel, F.1
Meye, A.2
Würl, P.3
-
46
-
-
0030795068
-
Translational enhancement of mdm2 oncogene expression in human tumor cells containing a stabilized wild-type p53 protein
-
Landers JE, Cassel SL, George DL. Translational enhancement of mdm2 oncogene expression in human tumor cells containing a stabilized wild-type p53 protein. Cancer Res 1997; 57: 3562-3568.
-
(1997)
Cancer Res
, vol.57
, pp. 3562-3568
-
-
Landers, J.E.1
Cassel, S.L.2
George, D.L.3
-
47
-
-
38849111754
-
MDM2 promoter polymorphism SNP309 contributes to tumor susceptibility: Evidence from 21 case-control studies
-
Hu Z, Jin G, Wang L, Chen F, Wang X, Shen H. MDM2 promoter polymorphism SNP309 contributes to tumor susceptibility: evidence from 21 case-control studies. Cancer Epidemiol Biomarkers Prev 2007; 16: 2717-2723.
-
(2007)
Cancer Epidemiol Biomarkers Prev
, vol.16
, pp. 2717-2723
-
-
Hu, Z.1
Jin, G.2
Wang, L.3
Chen, F.4
Wang, X.5
Shen, H.6
-
49
-
-
74849083374
-
Differential effects of MDM2 SNP309 polymorphism on breast cancer risk along with race: A meta-analysis
-
Economopoulos KP, Sergentanis TN. Differential effects of MDM2 SNP309 polymorphism on breast cancer risk along with race: a meta-analysis. Breast Cancer Res Treat 2010; 120: 211-216.
-
(2010)
Breast Cancer Res Treat
, vol.120
, pp. 211-216
-
-
Economopoulos, K.P.1
Sergentanis, T.N.2
-
50
-
-
84863003609
-
MDM2 SNP309 polymorphism and breast cancer risk: A meta-analysis
-
Zhao E, Cui D, Yuan L, Lu W. MDM2 SNP309 polymorphism and breast cancer risk: a meta-analysis. Mol Biol Rep 2012; 39: 3471-3477.
-
(2012)
Mol Biol Rep
, vol.39
, pp. 3471-3477
-
-
Zhao, E.1
Cui, D.2
Yuan, L.3
Lu, W.4
|