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Volumn 16, Issue 12, 2007, Pages 2717-2723

MDM2 promoter polymorphism SNP309 contributes to tumor susceptibility: Evidence from 21 case-control studies

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN MDM2; PROTEIN P53; TUMOR MARKER;

EID: 38849111754     PISSN: 10559965     EISSN: None     Source Type: Journal    
DOI: 10.1158/1055-9965.EPI-07-0634     Document Type: Article
Times cited : (99)

References (53)
  • 1
    • 0030941458 scopus 로고    scopus 로고
    • p53, the cellular gatekeeper for growth and division
    • Levine AJ. p53, the cellular gatekeeper for growth and division. Cell 1997;88:323-31.
    • (1997) Cell , vol.88 , pp. 323-331
    • Levine, A.J.1
  • 3
    • 18344377030 scopus 로고    scopus 로고
    • The p53 pathway: Positive and negative feedback loops
    • Harris SL, Levine AJ. The p53 pathway: positive and negative feedback loops. Oncogene 2005;24:2899-908.
    • (2005) Oncogene , vol.24 , pp. 2899-2908
    • Harris, S.L.1    Levine, A.J.2
  • 5
    • 30944435091 scopus 로고    scopus 로고
    • Unleashing the power of p53: Lessons from mice and men
    • Poyurovsky MV, Prives C. Unleashing the power of p53: lessons from mice and men. Genes Dev 2006;20:125-31.
    • (2006) Genes Dev , vol.20 , pp. 125-131
    • Poyurovsky, M.V.1    Prives, C.2
  • 7
    • 0027232042 scopus 로고
    • p53 Mutation and MDM2 amplification in human soft tissue sarcomas
    • Leach FS, Tokino T, Meltzer P, et al. p53 Mutation and MDM2 amplification in human soft tissue sarcomas. Cancer Res 1993;53:2231-4.
    • (1993) Cancer Res , vol.53 , pp. 2231-2234
    • Leach, F.S.1    Tokino, T.2    Meltzer, P.3
  • 8
    • 0028946602 scopus 로고
    • Differential expression of multiple MDM2 messenger RNAs and proteins in normal and tumorigenic breast epithelial cells
    • Gudas JM, Nguyen H, Klein RC, Katayose D, Seth P, Cowan KH. Differential expression of multiple MDM2 messenger RNAs and proteins in normal and tumorigenic breast epithelial cells. Clin Cancer Res 1995;1:71-80.
    • (1995) Clin Cancer Res , vol.1 , pp. 71-80
    • Gudas, J.M.1    Nguyen, H.2    Klein, R.C.3    Katayose, D.4    Seth, P.5    Cowan, K.H.6
  • 9
    • 14644417208 scopus 로고    scopus 로고
    • p53-independent activities of MDM2 and their relevance to cancer therapy
    • Zhang Z, Zhang R. p53-independent activities of MDM2 and their relevance to cancer therapy. Curr Cancer Drug Targets 2005;5:9-20.
    • (2005) Curr Cancer Drug Targets , vol.5 , pp. 9-20
    • Zhang, Z.1    Zhang, R.2
  • 10
    • 0028049474 scopus 로고
    • Regulation of mdm2 expression by p53: Alternative promoters produce transcripts with nonidentical translation potential
    • Barak Y, Gottlieb E, Juven-Gershon T, Oren M. Regulation of mdm2 expression by p53: alternative promoters produce transcripts with nonidentical translation potential. Genes Dev 1994;8:1739-49.
    • (1994) Genes Dev , vol.8 , pp. 1739-1749
    • Barak, Y.1    Gottlieb, E.2    Juven-Gershon, T.3    Oren, M.4
  • 11
    • 0029131447 scopus 로고
    • A functional p53-responsive intronic promoter is contained within the human mdm2 gene
    • Zauberman A, Flusberg D, Haupt Y, Barak Y, Oren M. A functional p53-responsive intronic promoter is contained within the human mdm2 gene. Nucleic Acids Res 1995;23:2584-92.
    • (1995) Nucleic Acids Res , vol.23 , pp. 2584-2592
    • Zauberman, A.1    Flusberg, D.2    Haupt, Y.3    Barak, Y.4    Oren, M.5
  • 12
    • 8844278362 scopus 로고    scopus 로고
    • A single nucleotide polymorphism in the MDM2 promoter attenuates the p53 tumor suppressor pathway and accelerates tumor formation in humans
    • Bond GL, Hu W, Bond EE, et al. A single nucleotide polymorphism in the MDM2 promoter attenuates the p53 tumor suppressor pathway and accelerates tumor formation in humans. Cell 2004;119:591-602.
    • (2004) Cell , vol.119 , pp. 591-602
    • Bond, G.L.1    Hu, W.2    Bond, E.E.3
  • 13
    • 24944454674 scopus 로고    scopus 로고
    • The MDM2 promoter polymorphism SNP309T → G and the risk of uterine leiomyosarcoma, colorectal cancer, and squamous cell carcinoma of the head and neck
    • Alhopuro P, Ylisaukko-Oja SK, Koskinen WJ, et al. The MDM2 promoter polymorphism SNP309T → G and the risk of uterine leiomyosarcoma, colorectal cancer, and squamous cell carcinoma of the head and neck. J Med Genet 2005;42:694-8.
    • (2005) J Med Genet , vol.42 , pp. 694-698
    • Alhopuro, P.1    Ylisaukko-Oja, S.K.2    Koskinen, W.J.3
  • 14
    • 33846443195 scopus 로고    scopus 로고
    • Tumour selection advantage of non-dominant negative P53 mutations in homozygotic MDM2-309 colorectal cancer cells
    • Alazzouzi H, Suriano G, Guerra A, et al. Tumour selection advantage of non-dominant negative P53 mutations in homozygotic MDM2-309 colorectal cancer cells. J Med Genet 2007;44:75-80.
    • (2007) J Med Genet , vol.44 , pp. 75-80
    • Alazzouzi, H.1    Suriano, G.2    Guerra, A.3
  • 15
    • 33745783716 scopus 로고    scopus 로고
    • Association of breast cancer outcome with status of p53 and MDM2 SNP309
    • Boersma BJ, Howe TM, Goodman JE, et al. Association of breast cancer outcome with status of p53 and MDM2 SNP309. J Natl Cancer Inst 2006;98:911-9.
    • (2006) J Natl Cancer Inst , vol.98 , pp. 911-919
    • Boersma, B.J.1    Howe, T.M.2    Goodman, J.E.3
  • 16
    • 33746218700 scopus 로고    scopus 로고
    • No association of the MDM2 SNP309 polymorphism with risk of breast or ovarian cancer
    • Campbell IG, Eccles DM, Choong DY. No association of the MDM2 SNP309 polymorphism with risk of breast or ovarian cancer. Cancer Lett 2006;240:195-7.
    • (2006) Cancer Lett , vol.240 , pp. 195-197
    • Campbell, I.G.1    Eccles, D.M.2    Choong, D.Y.3
  • 17
    • 33749546905 scopus 로고    scopus 로고
    • MDM2 gene promoter polymorphisms and risk of lung cancer: A case-control analysis
    • Li G, Zhai X, Zhang Z, Chamberlain RM, Spitz MR, Wei Q. MDM2 gene promoter polymorphisms and risk of lung cancer: a case-control analysis. Carcinogenesis 2006;27:2028-33.
    • (2006) Carcinogenesis , vol.27 , pp. 2028-2033
    • Li, G.1    Zhai, X.2    Zhang, Z.3    Chamberlain, R.M.4    Spitz, M.R.5    Wei, Q.6
  • 18
    • 33744918197 scopus 로고    scopus 로고
    • Association of a functional polymorphism in the promoter of the MDM2 gene with risk of nonsmall cell lung cancer
    • Lind H, Zienolddiny S, Ekstrom PO, Skaug V, Haugen A. Association of a functional polymorphism in the promoter of the MDM2 gene with risk of nonsmall cell lung cancer. Int J Cancer 2006;119:718-21.
    • (2006) Int J Cancer , vol.119 , pp. 718-721
    • Lind, H.1    Zienolddiny, S.2    Ekstrom, P.O.3    Skaug, V.4    Haugen, A.5
  • 19
    • 33144460815 scopus 로고    scopus 로고
    • Association between MDM2-309 and age at colorectal cancer diagnosis according to p53 mutation status
    • Menin C, Scaini MC, De Salvo GL, et al. Association between MDM2-309 and age at colorectal cancer diagnosis according to p53 mutation status. J Natl Cancer Inst 2006;98:285-8.
    • (2006) J Natl Cancer Inst , vol.98 , pp. 285-288
    • Menin, C.1    Scaini, M.C.2    De Salvo, G.L.3
  • 20
    • 33645459643 scopus 로고    scopus 로고
    • No association between the MDM2-309 T/G promoter polymorphism and breast cancer in African-Americans or Whites
    • Millikan RC, Heard K, Winkel S, et al. No association between the MDM2-309 T/G promoter polymorphism and breast cancer in African-Americans or Whites. Cancer Epidemiol Biomarkers Prev 2006;15:175-7.
    • (2006) Cancer Epidemiol Biomarkers Prev , vol.15 , pp. 175-177
    • Millikan, R.C.1    Heard, K.2    Winkel, S.3
  • 21
    • 33750690647 scopus 로고    scopus 로고
    • MDM2T309G polymorphism is associated with bladder cancer
    • Onat OE, Tez M, Ozcelik T, Toruner GA. MDM2T309G polymorphism is associated with bladder cancer. Anticancer Res 2006;26:3473-5.
    • (2006) Anticancer Res , vol.26 , pp. 3473-3475
    • Onat, O.E.1    Tez, M.2    Ozcelik, T.3    Toruner, G.A.4
  • 24
    • 34447540243 scopus 로고    scopus 로고
    • MDM2 SNP309 accelerates familial breast carcinogenesis independently of estrogen signaling
    • Wasielewski M, Nagel JH, Brekelmans C, et al. MDM2 SNP309 accelerates familial breast carcinogenesis independently of estrogen signaling. Breast Cancer Res Treat 2007;104:153-7.
    • (2007) Breast Cancer Res Treat , vol.104 , pp. 153-157
    • Wasielewski, M.1    Nagel, J.H.2    Brekelmans, C.3
  • 25
    • 31544482118 scopus 로고    scopus 로고
    • The single nucleotide polymorphism IVS1 + 309 in mouse double minute 2 does not affect risk of familial breast cancer
    • Wilkening S, Bermejo JL, Burwinkel B, et al. The single nucleotide polymorphism IVS1 + 309 in mouse double minute 2 does not affect risk of familial breast cancer. Cancer Res 2006;66:646-8.
    • (2006) Cancer Res , vol.66 , pp. 646-648
    • Wilkening, S.1    Bermejo, J.L.2    Burwinkel, B.3
  • 26
    • 34447542807 scopus 로고    scopus 로고
    • No association between MDM2 SNP309 promoter polymorphism and basal cell carcinoma of the skin
    • Wilkening S, Hemminki K, Rudnai P, et al. No association between MDM2 SNP309 promoter polymorphism and basal cell carcinoma of the skin. Br J Dermatol 2007;157:375-7.
    • (2007) Br J Dermatol , vol.157 , pp. 375-377
    • Wilkening, S.1    Hemminki, K.2    Rudnai, P.3
  • 27
    • 33748344945 scopus 로고    scopus 로고
    • MDM2 promoter SNP309 is associated with the risk of hepatocellular carcinoma in patients with chronic hepatitis C
    • Dharel N, Kato N, Muroyama R, et al. MDM2 promoter SNP309 is associated with the risk of hepatocellular carcinoma in patients with chronic hepatitis C. Clin Cancer Res 2006;12:4867-71.
    • (2006) Clin Cancer Res , vol.12 , pp. 4867-4871
    • Dharel, N.1    Kato, N.2    Muroyama, R.3
  • 28
    • 27144529920 scopus 로고    scopus 로고
    • The role of P53 and MDM2 polymorphisms in the risk of esophageal squamous cell carcinoma
    • Hong Y, Miao X, Zhang X, et al. The role of P53 and MDM2 polymorphisms in the risk of esophageal squamous cell carcinoma. Cancer Res 2005;65:9582-7.
    • (2005) Cancer Res , vol.65 , pp. 9582-9587
    • Hong, Y.1    Miao, X.2    Zhang, X.3
  • 29
    • 31844433337 scopus 로고    scopus 로고
    • Genetic variants in the MDM2 promoter and lung cancer risk in a Chinese population
    • Hu Z, Ma H, Lu D, et al. Genetic variants in the MDM2 promoter and lung cancer risk in a Chinese population. Int J Cancer 2006;118:1275-8.
    • (2006) Int J Cancer , vol.118 , pp. 1275-1278
    • Hu, Z.1    Ma, H.2    Lu, D.3
  • 30
    • 33746239400 scopus 로고    scopus 로고
    • Polymorphisms in the MDM2 promoter and risk of breast cancer: A case-control analysis in a Chinese population
    • Ma H, Hu Z, Zhai X, et al. Polymorphisms in the MDM2 promoter and risk of breast cancer: a case-control analysis in a Chinese population. Cancer Lett 2006;240:261-7.
    • (2006) Cancer Lett , vol.240 , pp. 261-267
    • Ma, H.1    Hu, Z.2    Zhai, X.3
  • 31
    • 33749040649 scopus 로고    scopus 로고
    • MDM2 promoter polymorphism is associated with both an increased susceptibility to gastric carcinoma and poor prognosis
    • Ohmiya N, Taguchi A, Mabuchi N, et al. MDM2 promoter polymorphism is associated with both an increased susceptibility to gastric carcinoma and poor prognosis. J Clin Oncol 2006;24:4434-40.
    • (2006) J Clin Oncol , vol.24 , pp. 4434-4440
    • Ohmiya, N.1    Taguchi, A.2    Mabuchi, N.3
  • 32
    • 33750297735 scopus 로고    scopus 로고
    • MDM2 309T>G polymorphism and risk of lung cancer in a Korean population
    • Park SH, Choi JE, Kim EJ, et al. MDM2 309T>G polymorphism and risk of lung cancer in a Korean population. Lung Cancer 2006;54:19-24.
    • (2006) Lung Cancer , vol.54 , pp. 19-24
    • Park, S.H.1    Choi, J.E.2    Kim, E.J.3
  • 33
    • 29944441900 scopus 로고    scopus 로고
    • Genetic polymorphisms in cell cycle regulatory genes MDM2 and TP53 are associated with susceptibility to lung cancer
    • Zhang X, Miao X, Guo Y, et al. Genetic polymorphisms in cell cycle regulatory genes MDM2 and TP53 are associated with susceptibility to lung cancer. Hum Mutat 2006;27:110-7.
    • (2006) Hum Mutat , vol.27 , pp. 110-117
    • Zhang, X.1    Miao, X.2    Guo, Y.3
  • 34
    • 34547220487 scopus 로고    scopus 로고
    • MDM2 SNP309 polymorphism as risk factor for susceptibility and poor prognosis in renal cell carcinoma
    • Hirata H, Hinoda Y, Kikuno N, et al. MDM2 SNP309 polymorphism as risk factor for susceptibility and poor prognosis in renal cell carcinoma. Clin Cancer Res 2007;13:4123-9.
    • (2007) Clin Cancer Res , vol.13 , pp. 4123-4129
    • Hirata, H.1    Hinoda, Y.2    Kikuno, N.3
  • 35
    • 34249103659 scopus 로고    scopus 로고
    • MDM2 promoter SNP309 is associated with risk of occurrence and advanced lymph node metastasis of nasopharyngeal carcinoma in Chinese population
    • Zhou G, Zhai Y, Cui Y, et al. MDM2 promoter SNP309 is associated with risk of occurrence and advanced lymph node metastasis of nasopharyngeal carcinoma in Chinese population. Clin Cancer Res 2007;13:2627-33.
    • (2007) Clin Cancer Res , vol.13 , pp. 2627-2633
    • Zhou, G.1    Zhai, Y.2    Cui, Y.3
  • 36
    • 33846954399 scopus 로고    scopus 로고
    • Association between a functional single nucleotide polymorphism in the MDM2 gene and sporadic endometrial cancer risk
    • Walsh CS, Miller CW, Karlan BY, Koeffler HP. Association between a functional single nucleotide polymorphism in the MDM2 gene and sporadic endometrial cancer risk. Gynecol Oncol 2007;104:660-4.
    • (2007) Gynecol Oncol , vol.104 , pp. 660-664
    • Walsh, C.S.1    Miller, C.W.2    Karlan, B.Y.3    Koeffler, H.P.4
  • 37
    • 34249982811 scopus 로고    scopus 로고
    • 72Pro and MDM2-309 polymorphisms and risk of breast cancer in the nurses' health studies
    • 72Pro and MDM2-309 polymorphisms and risk of breast cancer in the nurses' health studies. Cancer Causes Control 2007;18:621-5.
    • (2007) Cancer Causes Control , vol.18 , pp. 621-625
    • Cox, D.G.1    Deer, D.2    Guo, Q.3
  • 38
    • 33745612767 scopus 로고    scopus 로고
    • Influence of the MDM2 single nucleotide polymorphism SNP309 on tumour development in BRCA1 mutation carriers
    • Copson ER, White HE, Blaydes JP, Robinson DO, Johnson PW, Eccles DM. Influence of the MDM2 single nucleotide polymorphism SNP309 on tumour development in BRCA1 mutation carriers. BMC Cancer 2006;6:80.
    • (2006) BMC Cancer , vol.6 , pp. 80
    • Copson, E.R.1    White, H.E.2    Blaydes, J.P.3    Robinson, D.O.4    Johnson, P.W.5    Eccles, D.M.6
  • 40
    • 0030693603 scopus 로고    scopus 로고
    • Quantitative synthesis in systematic reviews
    • Lau J, Ioannidis JP, Schmid CH. Quantitative synthesis in systematic reviews. Ann Intern Med 1997;127:820-6.
    • (1997) Ann Intern Med , vol.127 , pp. 820-826
    • Lau, J.1    Ioannidis, J.P.2    Schmid, C.H.3
  • 41
    • 0026009636 scopus 로고
    • A general parametric approach to the meta-analysis of randomized clinical trials
    • Whitehead A, Whitehead J. A general parametric approach to the meta-analysis of randomized clinical trials. Stat Med 1991;10:1665-77.
    • (1991) Stat Med , vol.10 , pp. 1665-1677
    • Whitehead, A.1    Whitehead, J.2
  • 42
    • 0030922816 scopus 로고    scopus 로고
    • Egger M, Davey Smith G, Schneider M, Minder C. Bias in meta-analysis detected by a simple, graphical test. BMJ 1997;315:629-34.
    • Egger M, Davey Smith G, Schneider M, Minder C. Bias in meta-analysis detected by a simple, graphical test. BMJ 1997;315:629-34.
  • 43
    • 21344470650 scopus 로고    scopus 로고
    • A single nucleotide polymorphism in the MDM2 gene: From a molecular and cellular explanation to clinical effect
    • Bond GL, Hu W, Levine A. A single nucleotide polymorphism in the MDM2 gene: from a molecular and cellular explanation to clinical effect. Cancer Res 2005;65:5481-4.
    • (2005) Cancer Res , vol.65 , pp. 5481-5484
    • Bond, G.L.1    Hu, W.2    Levine, A.3
  • 44
    • 0028983308 scopus 로고
    • mdm2 gene alterations and mdm2 protein expression in breast carcinomas
    • Marchetti A, Buttitta F, Girlando S, et al. mdm2 gene alterations and mdm2 protein expression in breast carcinomas. J Pathol 1995;175:31-8.
    • (1995) J Pathol , vol.175 , pp. 31-38
    • Marchetti, A.1    Buttitta, F.2    Girlando, S.3
  • 47
    • 0037505736 scopus 로고    scopus 로고
    • p53-independent activation of the hdm2-2 promoter through multiple transcription factor response elements results in elevated hdm2 expression in estrogen receptor a- positive breast cancer cells
    • Phelps M, Darley M, Primrose JN, Blaydes JP. p53-independent activation of the hdm2-2 promoter through multiple transcription factor response elements results in elevated hdm2 expression in estrogen receptor a- positive breast cancer cells. Cancer Res 2003;63:2616-23.
    • (2003) Cancer Res , vol.63 , pp. 2616-2623
    • Phelps, M.1    Darley, M.2    Primrose, J.N.3    Blaydes, J.P.4
  • 48
    • 34047247060 scopus 로고    scopus 로고
    • A single nucleotide polymorphism in the MDM2 gene disrupts the oscillation of p53 and MDM2 levels in cells
    • Hu W, Feng Z, Ma L, et al. A single nucleotide polymorphism in the MDM2 gene disrupts the oscillation of p53 and MDM2 levels in cells. Cancer Res 2007;67:2757-65.
    • (2007) Cancer Res , vol.67 , pp. 2757-2765
    • Hu, W.1    Feng, Z.2    Ma, L.3
  • 49
    • 33744899069 scopus 로고    scopus 로고
    • MDM2 SNP309 accelerates tumor formation in a gender-specific and hormone-dependent manner
    • Bond GL, Hirshfield KM, Kirchhoff T, et al. MDM2 SNP309 accelerates tumor formation in a gender-specific and hormone-dependent manner. Cancer Res 2006;66:5104-10.
    • (2006) Cancer Res , vol.66 , pp. 5104-5110
    • Bond, G.L.1    Hirshfield, K.M.2    Kirchhoff, T.3
  • 50
  • 52
    • 33845530151 scopus 로고    scopus 로고
    • The single-nucleotide polymorphism 309 in the MDM2 gene contributes to the Li-Fraumeni syndrome and related phenotypes
    • Ruijs MW, Schmidt MK, Nevanlinna H, et al. The single-nucleotide polymorphism 309 in the MDM2 gene contributes to the Li-Fraumeni syndrome and related phenotypes. Eur J Hum Genet 2007;15:110-4.
    • (2007) Eur J Hum Genet , vol.15 , pp. 110-114
    • Ruijs, M.W.1    Schmidt, M.K.2    Nevanlinna, H.3
  • 53
    • 33847691863 scopus 로고    scopus 로고
    • Younger age of cancer initiation is associated with shorter telomere length in Li-Fraumeni syndrome
    • Tabori U, Nanda S, Druker H, Lees J, Malkin D. Younger age of cancer initiation is associated with shorter telomere length in Li-Fraumeni syndrome. Cancer Res 2007;67:1415-8.
    • (2007) Cancer Res , vol.67 , pp. 1415-1418
    • Tabori, U.1    Nanda, S.2    Druker, H.3    Lees, J.4    Malkin, D.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.