-
1
-
-
0033281771
-
How many more breast cancer predisposition genes are there?
-
Easton DF. How many more breast cancer predisposition genes are there? Breast Cancer Res 1999;1:14-7.
-
(1999)
Breast Cancer Res
, vol.1
, pp. 14-17
-
-
Easton, D.F.1
-
3
-
-
33749571327
-
Commonly studied single-nucleotide polymorphisms and breast cancer: Results from the Breast Cancer Association Consortium
-
The Breast Cancer Association Consortium
-
The Breast Cancer Association Consortium. Commonly studied single-nucleotide polymorphisms and breast cancer: results from the Breast Cancer Association Consortium. J Natl Cancer Inst 2006;98:1382-96.
-
(2006)
J Natl Cancer Inst
, vol.98
, pp. 1382-1396
-
-
-
4
-
-
33749002551
-
Models of genetic susceptibility to breast cancer
-
Antoniou AC, Easton DF. Models of genetic susceptibility to breast cancer. Oncogene 2006;25:5898-905.
-
(2006)
Oncogene
, vol.25
, pp. 5898-5905
-
-
Antoniou, A.C.1
Easton, D.F.2
-
5
-
-
33746491583
-
ATM mutations that cause ataxia-telangiectasia are breast cancer susceptibility alleles
-
Renwick A, Thompson D, Seal S, et al. ATM mutations that cause ataxia-telangiectasia are breast cancer susceptibility alleles. Nat Genet 2006;38:873-5.
-
(2006)
Nat Genet
, vol.38
, pp. 873-875
-
-
Renwick, A.1
Thompson, D.2
Seal, S.3
-
6
-
-
18544389716
-
Low-penetrance susceptibility to breast cancer due to CHEK2(*)1100delC in noncarriers of BRCA1 or BRCA2 mutations
-
Meijers-Heijboer H, van den Ouweland A, Klijn J, et al. Low-penetrance susceptibility to breast cancer due to CHEK2(*)1100delC in noncarriers of BRCA1 or BRCA2 mutations. Nat Genet 2002;31:55-9.
-
(2002)
Nat Genet
, vol.31
, pp. 55-59
-
-
Meijers-Heijboer, H.1
van den Ouweland, A.2
Klijn, J.3
-
7
-
-
33750465216
-
-
Seal S, Thompson D, Renwick A, et al. Truncating mutations in the Fanconi anemia J gene BRIP1 are low-penetrance breast cancer susceptibility alleles. Nat Genet 2006;38:1239-41.
-
Seal S, Thompson D, Renwick A, et al. Truncating mutations in the Fanconi anemia J gene BRIP1 are low-penetrance breast cancer susceptibility alleles. Nat Genet 2006;38:1239-41.
-
-
-
-
8
-
-
33846625493
-
PALB2, which encodes a BRCA2-interacting protein, is a breast cancer susceptibility gene
-
Rahman N, Seal S, Thompson D, et al. PALB2, which encodes a BRCA2-interacting protein, is a breast cancer susceptibility gene. Nat Genet 2007;39:165-7.
-
(2007)
Nat Genet
, vol.39
, pp. 165-167
-
-
Rahman, N.1
Seal, S.2
Thompson, D.3
-
9
-
-
33847337318
-
A common coding variant in CASP8 is associated with breast cancer risk
-
Cox A, Dunning AM, Garcia-Closas M, et al. A common coding variant in CASP8 is associated with breast cancer risk. Nat Genet 2007;39:352-8.
-
(2007)
Nat Genet
, vol.39
, pp. 352-358
-
-
Cox, A.1
Dunning, A.M.2
Garcia-Closas, M.3
-
10
-
-
21344470650
-
A single nucleotide polymorphism in the MDM2 gene: From a molecular and cellular explanation to clinical effect
-
Bond GL, Hu W, Levine A. A single nucleotide polymorphism in the MDM2 gene: from a molecular and cellular explanation to clinical effect. Cancer Res 2005;65:5481-4.
-
(2005)
Cancer Res
, vol.65
, pp. 5481-5484
-
-
Bond, G.L.1
Hu, W.2
Levine, A.3
-
11
-
-
14644403700
-
MDM2 and human malignancies: Expression, clinical pathology, prognostic markers, and implications for chemotherapy
-
Rayburn E, Zhang R, He J, Wang H. MDM2 and human malignancies: expression, clinical pathology, prognostic markers, and implications for chemotherapy. Curr Cancer Drug Targets 2005;5:27-41.
-
(2005)
Curr Cancer Drug Targets
, vol.5
, pp. 27-41
-
-
Rayburn, E.1
Zhang, R.2
He, J.3
Wang, H.4
-
12
-
-
8844278362
-
A single nucleotide polymorphism in the MDM2 promoter attenuates the p53 tumor suppressor pathway and accelerates tumor formation in humans
-
Bond GL, Hu W, Bond EE, et al. A single nucleotide polymorphism in the MDM2 promoter attenuates the p53 tumor suppressor pathway and accelerates tumor formation in humans. Cell 2004;119:591-602.
-
(2004)
Cell
, vol.119
, pp. 591-602
-
-
Bond, G.L.1
Hu, W.2
Bond, E.E.3
-
13
-
-
33745235771
-
Impact of the MDM2 SNP309 and p53 Arg72Pro polymorphism on age of tumour onset in Li-Fraumeni syndrome
-
Bougeard G, Baert-Desurmont S, Tournier I, et al. Impact of the MDM2 SNP309 and p53 Arg72Pro polymorphism on age of tumour onset in Li-Fraumeni syndrome. J Med Genet 2006;43:531-3.
-
(2006)
J Med Genet
, vol.43
, pp. 531-533
-
-
Bougeard, G.1
Baert-Desurmont, S.2
Tournier, I.3
-
14
-
-
33845530151
-
The single nucleotide polymorphism 309 in the MDM2 gene contributes to the Li-Fraumeni syndrome and related phenotypes
-
Ruijs MWG, Schmidt MK, Nevanlinna H, et al. The single nucleotide polymorphism 309 in the MDM2 gene contributes to the Li-Fraumeni syndrome and related phenotypes. Eur J Hum Genet 2007;15:110-4.
-
(2007)
Eur J Hum Genet
, vol.15
, pp. 110-114
-
-
Ruijs, M.W.G.1
Schmidt, M.K.2
Nevanlinna, H.3
-
15
-
-
33144460815
-
Association between MDM2-SNP309 and age at colorectal cancer diagnosis according to p53 mutation status
-
Menin C, Scaini M, De Salvo G, et al. Association between MDM2-SNP309 and age at colorectal cancer diagnosis according to p53 mutation status. J Natl Cancer Inst 2006;98:285-8.
-
(2006)
J Natl Cancer Inst
, vol.98
, pp. 285-288
-
-
Menin, C.1
Scaini, M.2
De Salvo, G.3
-
16
-
-
33846133702
-
MDM2 SNP309 accelerates colorectal tumour formation in women
-
Bond G, Menin C, Bertorelle R, Alhopuro P, Aaltonen L, Levine A. MDM2 SNP309 accelerates colorectal tumour formation in women. J Med Genet 2006;43:950-2.
-
(2006)
J Med Genet
, vol.43
, pp. 950-952
-
-
Bond, G.1
Menin, C.2
Bertorelle, R.3
Alhopuro, P.4
Aaltonen, L.5
Levine, A.6
-
17
-
-
33749040649
-
MDM2 promoter polymorphism is associated with both an increased susceptibility to gastric carcinoma and poor prognosis
-
Ohmiya N, Taguchi A, Mabuchi N, et al. MDM2 promoter polymorphism is associated with both an increased susceptibility to gastric carcinoma and poor prognosis. J Clin Oncol 2006;24:4434-40.
-
(2006)
J Clin Oncol
, vol.24
, pp. 4434-4440
-
-
Ohmiya, N.1
Taguchi, A.2
Mabuchi, N.3
-
18
-
-
33645459643
-
No association between the MDM2 -309 T/G promoter polymorphism and breast cancer in African-Americans or Whites. Cancer Epidemiol
-
Millikan R, Heard K, Winkel S, et al. No association between the MDM2 -309 T/G promoter polymorphism and breast cancer in African-Americans or Whites. Cancer Epidemiol Biomarkers Prev2006; 15:175-7.
-
Biomarkers Prev2006
, vol.15
, pp. 175-177
-
-
Millikan, R.1
Heard, K.2
Winkel, S.3
-
19
-
-
33746239400
-
Polymorphisms in the MDM2 promoter and risk of breast cancer: A case-control analysis in a Chinese population
-
Ma H, Hu Z, Zhai X, et al. Polymorphisms in the MDM2 promoter and risk of breast cancer: a case-control analysis in a Chinese population. Cancer Lett 2006;240:261-7.
-
(2006)
Cancer Lett
, vol.240
, pp. 261-267
-
-
Ma, H.1
Hu, Z.2
Zhai, X.3
-
20
-
-
31544482118
-
The single nucleotide polymorphism IVS1+309 in mouse double minute 2 does not affect risk of familial breast cancer
-
Wilkening S, Bermejo J, Burwinkel B, et al. The single nucleotide polymorphism IVS1+309 in mouse double minute 2 does not affect risk of familial breast cancer. Cancer Res 2006;66:646-8.
-
(2006)
Cancer Res
, vol.66
, pp. 646-648
-
-
Wilkening, S.1
Bermejo, J.2
Burwinkel, B.3
-
21
-
-
33746218700
-
No association of the MDM2 SNP309 polymorphism with risk of breast or ovarian cancer
-
Campbell IG, Eccles DM, Choong DY. No association of the MDM2 SNP309 polymorphism with risk of breast or ovarian cancer. Cancer Lett 2006;240:195-7.
-
(2006)
Cancer Lett
, vol.240
, pp. 195-197
-
-
Campbell, I.G.1
Eccles, D.M.2
Choong, D.Y.3
-
22
-
-
33745783716
-
Association of breast cancer outcome with status of p53 and MDM2 SNP309
-
Boersma B, Howe T, Goodman J, et al. Association of breast cancer outcome with status of p53 and MDM2 SNP309. J Natl Cancer Inst 2006;98:911-9.
-
(2006)
J Natl Cancer Inst
, vol.98
, pp. 911-919
-
-
Boersma, B.1
Howe, T.2
Goodman, J.3
-
23
-
-
33845944092
-
Lack of association between the MDM2-SNP309 polymorphism and breast cancer risk
-
Petenkaya A, Bozkurt B, Akilli-Ozturk O, Kaya HS, Gur-Dedeoglu B, Yulug IG. Lack of association between the MDM2-SNP309 polymorphism and breast cancer risk. Anticancer Res 2006;26:4975-7.
-
(2006)
Anticancer Res
, vol.26
, pp. 4975-4977
-
-
Petenkaya, A.1
Bozkurt, B.2
Akilli-Ozturk, O.3
Kaya, H.S.4
Gur-Dedeoglu, B.5
Yulug, I.G.6
-
24
-
-
0034810227
-
MDM2 enhances the function of estrogen receptor α in human breast cancer cells
-
Saji S, Okumura N, Eguchi H, et al. MDM2 enhances the function of estrogen receptor α in human breast cancer cells. Biochem Biophys Res Commun 2001;281:259-65.
-
(2001)
Biochem Biophys Res Commun
, vol.281
, pp. 259-265
-
-
Saji, S.1
Okumura, N.2
Eguchi, H.3
-
25
-
-
33744899069
-
MDM2 SNP309 accelerates tumor formation in a gender-specific and hormone-dependent manner
-
Bond G, Hirshfield K, Kirchhoff T, et al. MDM2 SNP309 accelerates tumor formation in a gender-specific and hormone-dependent manner. Cancer Res 2006;66:5104-10.
-
(2006)
Cancer Res
, vol.66
, pp. 5104-5110
-
-
Bond, G.1
Hirshfield, K.2
Kirchhoff, T.3
-
26
-
-
0036258111
-
The IARC TP53 database: New online mutation analysis and recommendations to users (Note: data used from latest version R10 July, 2005)
-
Olivier M, Eeles R, Hollstein M, Khan MA, Harris CC Hainaut P. The IARC TP53 database: new online mutation analysis and recommendations to users (Note: data used from latest version R10 July, 2005). Hum Mutat 2002;19:607-14.
-
(2002)
Hum Mutat
, vol.19
, pp. 607-614
-
-
Olivier, M.1
Eeles, R.2
Hollstein, M.3
Khan, M.A.4
Harris, C.C.5
Hainaut, P.6
-
28
-
-
4444324188
-
p53 polymorphism and age of onset of hereditary nonpolyposis colorectal cancer in a Caucasian population
-
Jones JS, Chi X, Gu X, Lynch P, Amos C, Frazier M. p53 polymorphism and age of onset of hereditary nonpolyposis colorectal cancer in a Caucasian population. Clin Cancer Res 2004;10:5845-9.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 5845-5849
-
-
Jones, J.S.1
Chi, X.2
Gu, X.3
Lynch, P.4
Amos, C.5
Frazier, M.6
-
29
-
-
22344450943
-
Breast cancer patients with p53 Pro72 homozygous genotype have a poorer survival
-
Tommiska J, Eerola H, Heinonen M, et al. Breast cancer patients with p53 Pro72 homozygous genotype have a poorer survival. Clin Cancer Res 2005;11:5098-103.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 5098-5103
-
-
Tommiska, J.1
Eerola, H.2
Heinonen, M.3
-
30
-
-
0037372005
-
The codon 72 polymorphic variants of p53 have markedly different apoptotic potential
-
Dumont P, Leu JI, Della Pietra AC III, George DL Murphy M. The codon 72 polymorphic variants of p53 have markedly different apoptotic potential. Nat Genet 2003;33:357-65.
-
(2003)
Nat Genet
, vol.33
, pp. 357-365
-
-
Dumont, P.1
Leu, J.I.2
Della Pietra III, A.C.3
George, D.L.4
Murphy, M.5
-
31
-
-
33745116207
-
Trp53-dependent DNA-repair is affected by the codon 72 polymorphism
-
Siddique M, Sabapathy K. Trp53-dependent DNA-repair is affected by the codon 72 polymorphism. Oncogene 2006;25:3489-500.
-
(2006)
Oncogene
, vol.25
, pp. 3489-3500
-
-
Siddique, M.1
Sabapathy, K.2
-
32
-
-
0037390957
-
Germline TP53 mutations in breast cancer families with multiple primary cancers: Is TP53 a modifier of BRCA1?
-
Martin AM, Kanetsky PA, Amirimani B, et al. Germline TP53 mutations in breast cancer families with multiple primary cancers: is TP53 a modifier of BRCA1? J Med Genet 2003;40:34e.
-
(2003)
J Med Genet
, vol.40
-
-
Martin, A.M.1
Kanetsky, P.A.2
Amirimani, B.3
-
33
-
-
33645226075
-
A haplotype containing the p53 polymorphisms Ins16bp and Arg72Pro modifies cancer risk in BRCA2 mutation carriers
-
Osorio A, Martinez-Delgado B, Pollan M, et al. A haplotype containing the p53 polymorphisms Ins16bp and Arg72Pro modifies cancer risk in BRCA2 mutation carriers. Hum Mutat 2006;27:242-8.
-
(2006)
Hum Mutat
, vol.27
, pp. 242-248
-
-
Osorio, A.1
Martinez-Delgado, B.2
Pollan, M.3
-
34
-
-
26444518246
-
p53 codon 72 and MDM2 SNP309 polymorphisms and age of colorectal cancer onset in Lynch syndrome
-
Sotamaa K, Liyanarachchi S, Mecklin JP, et al. p53 codon 72 and MDM2 SNP309 polymorphisms and age of colorectal cancer onset in Lynch syndrome. Clin Cancer Res 2005;11:6840-4.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 6840-6844
-
-
Sotamaa, K.1
Liyanarachchi, S.2
Mecklin, J.P.3
-
35
-
-
35148856495
-
Functional polymorphisms of MDM2 and TP53 may modulate the age at onset of breast cancer [abstract]
-
Reincke SA, Bremer M, Karstens JH, Sohn C, Dammann O, Dörk T. Functional polymorphisms of MDM2 and TP53 may modulate the age at onset of breast cancer [abstract]. Medgen 2006;18:56.
-
(2006)
Medgen
, vol.18
, pp. 56
-
-
Reincke, S.A.1
Bremer, M.2
Karstens, J.H.3
Sohn, C.4
Dammann, O.5
Dörk, T.6
-
36
-
-
0036499241
-
Sample size requirements for association studies of gene-gene interaction
-
Gauderman WJ. Sample size requirements for association studies of gene-gene interaction. Am J Epidemiol 2002;155:478-84.
-
(2002)
Am J Epidemiol
, vol.155
, pp. 478-484
-
-
Gauderman, W.J.1
-
37
-
-
35148846700
-
-
Gauderman WJ, Morrison JM. QUANTO 1.1: a computer program for power and sample size calculations for genetic-epidemiology studies. 2006. Available from: http://hydra.usc.edu/gxe.
-
Gauderman WJ, Morrison JM. QUANTO 1.1: a computer program for power and sample size calculations for genetic-epidemiology studies. 2006. Available from: http://hydra.usc.edu/gxe.
-
-
-
-
38
-
-
24944454674
-
The MDM2 promoter polymorphism SNP309T→G and the risk of uterine leiomyosarcoma, colorectal cancer, and squamous cell carcinoma of the head and neck
-
Alhopuro P, Ylisaukko-oja, SK, Koskinen WJ, et al. The MDM2 promoter polymorphism SNP309T→G and the risk of uterine leiomyosarcoma, colorectal cancer, and squamous cell carcinoma of the head and neck. J Med Genet 2005;42:694-8.
-
(2005)
J Med Genet
, vol.42
, pp. 694-698
-
-
Alhopuro, P.1
Ylisaukko-oja, S.K.2
Koskinen, W.J.3
-
39
-
-
34447540243
-
MDM2 SNP309 accelerates familial breast carcinogenesis independently of estrogen signaling
-
Wasielewski M, Nagel JH, Brekelmans C, et al. MDM2 SNP309 accelerates familial breast carcinogenesis independently of estrogen signaling. Breast Cancer Res Treat 2007;104:153-7.
-
(2007)
Breast Cancer Res Treat
, vol.104
, pp. 153-157
-
-
Wasielewski, M.1
Nagel, J.H.2
Brekelmans, C.3
-
40
-
-
0034692434
-
Population-based study of BRCA1 and BRCA2 mutations in 1035 unselected Finnish breast cancer patients
-
Syrjakoski K, Vahteristo P, Eerola H, et al. Population-based study of BRCA1 and BRCA2 mutations in 1035 unselected Finnish breast cancer patients. J Natl Cancer Inst 2000;92:1529-31.
-
(2000)
J Natl Cancer Inst
, vol.92
, pp. 1529-1531
-
-
Syrjakoski, K.1
Vahteristo, P.2
Eerola, H.3
-
41
-
-
0035860153
-
Mutations of the BRCA1 and BRCA2 genes in patients with bilateral breast cancer
-
Steinmann D, Bremer M, Rades D, et al. Mutations of the BRCA1 and BRCA2 genes in patients with bilateral breast cancer. Br J Cancer 2001;85:850-8.
-
(2001)
Br J Cancer
, vol.85
, pp. 850-858
-
-
Steinmann, D.1
Bremer, M.2
Rades, D.3
-
42
-
-
0035887491
-
Spectrum of ATM gene mutations in a hospital-based series of unselected breast cancer patients
-
Dork T, Bendix R, Bremer M, et al. Spectrum of ATM gene mutations in a hospital-based series of unselected breast cancer patients. Cancer Res 2001;61:7608-15.
-
(2001)
Cancer Res
, vol.61
, pp. 7608-7615
-
-
Dork, T.1
Bendix, R.2
Bremer, M.3
-
43
-
-
34250197864
-
Identification of women with an increased risk of developing radiation-induced breast cancer: A case only study
-
Broeks A, Braaf LM, Huseinovic A, et al. Identification of women with an increased risk of developing radiation-induced breast cancer: a case only study. Breast Cancer Res 2007;9:R26.
-
(2007)
Breast Cancer Res
, vol.9
-
-
Broeks, A.1
Braaf, L.M.2
Huseinovic, A.3
-
44
-
-
34547735957
-
Breast cancer survival and tumor characteristics in premenopausal women carrying the CHEK2*1100delC germline mutation
-
Schmidt MK, Tollenaar RAEM, de Kemp SR, et al. Breast cancer survival and tumor characteristics in premenopausal women carrying the CHEK2*1100delC germline mutation. J Clin Oncol 2007;25:64-9.
-
(2007)
J Clin Oncol
, vol.25
, pp. 64-69
-
-
Schmidt, M.K.1
Tollenaar, R.A.E.M.2
de Kemp, S.R.3
-
45
-
-
33748103002
-
Genetic variants in epigenetic genes and breast cancer risk
-
Cebrian A, Pharoah P, Ahmed S, et al. Genetic variants in epigenetic genes and breast cancer risk. Carcinogenesis 2006;27:1661-9.
-
(2006)
Carcinogenesis
, vol.27
, pp. 1661-1669
-
-
Cebrian, A.1
Pharoah, P.2
Ahmed, S.3
-
46
-
-
27544515629
-
Interaction between CHEK2*1100delC and other low-penetrance breast-cancer susceptibility genes: A familial study
-
Johnson N, Fletcher O, Naceur-Lombardelli C, dos Santos Silva I, Ashworth A, Peto J. Interaction between CHEK2*1100delC and other low-penetrance breast-cancer susceptibility genes: a familial study. Lancet 2005;366:1554-7.
-
(2005)
Lancet
, vol.366
, pp. 1554-1557
-
-
Johnson, N.1
Fletcher, O.2
Naceur-Lombardelli, C.3
dos Santos Silva, I.4
Ashworth, A.5
Peto, J.6
-
47
-
-
33746768935
-
Inconsistent association between the STK15 F31I genetic polymorphism and breast cancer risk
-
Fletcher O, Johnson N, Palles C, et al. Inconsistent association between the STK15 F31I genetic polymorphism and breast cancer risk. J Natl Cancer Inst 2006;98:1014-8.
-
(2006)
J Natl Cancer Inst
, vol.98
, pp. 1014-1018
-
-
Fletcher, O.1
Johnson, N.2
Palles, C.3
|