Using Answer Set Programming to Integrate RNA Expression with Signalling Pathway Information to Infer How Mutations Affect Ageing

PLoS ONE

Volumn 7, Issue 12, 2012, Pages

  Papatheodorou, Irene ^a,b   Ziehm, Matthias ^a   Wieser, Daniela ^a   Alic, Nazif ^b   Partridge, Linda ^b,c   Thornton, Janet M ^a  

^a WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c MAX PLANCK INSTITUTE FOR BIOLOGY OF AGEING   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN KINASE B; RNA; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR FOXO;

AGING; ANALYTIC METHOD; ANSWER SET PROGRAMMING; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; DROSOPHILA; GENE EXPRESSION; HOMEOSTASIS; HOMOZYGOSITY; LIFESPAN; LONGEVITY; MORPHOGENESIS; NEGATIVE FEEDBACK; NONHUMAN; PHENOTYPE; PROTEIN CROSS LINKING; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEOMICS; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION; STIMULATION; TRANSCRIPTION REGULATION;

AGING; ANIMALS; DROSOPHILA; GENE EXPRESSION; LONGEVITY; MODELS, GENETIC; MUTATION; RECEPTOR, INSULIN; RNA; SIGNAL TRANSDUCTION;

ANIMALIA;

EID: 84870955752     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0050881     Document Type: Article

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