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Volumn 324, Issue 1-2, 2013, Pages 10-16

Environmental factors and their regulation of immunity in multiple sclerosis

Author keywords

Autoimmunity; Epidemiology; Immunology; Multiple sclerosis; Risk factors

Indexed keywords

CD147 ANTIGEN; EXCITOTOXIN; FREE RADICAL; GLUTAMIC ACID; MYELIN BASIC PROTEIN; T LYMPHOCYTE RECEPTOR; VITAMIN D;

EID: 84870913364     PISSN: 0022510X     EISSN: 18785883     Source Type: Journal    
DOI: 10.1016/j.jns.2012.10.021     Document Type: Review
Times cited : (57)

References (88)
  • 1
    • 34447508481 scopus 로고    scopus 로고
    • Environmental risk factors for multiple sclerosis. Part II: Noninfectious factors
    • A. Ascherio, and K.L. Munger Environmental risk factors for multiple sclerosis. Part II: noninfectious factors Ann Neurol 61 6 Jun 2007 504 513
    • (2007) Ann Neurol , vol.61 , Issue.6 , pp. 504-513
    • Ascherio, A.1    Munger, K.L.2
  • 4
    • 0036831056 scopus 로고    scopus 로고
    • Organic solvents and the risk of multiple sclerosis
    • T. Riise, B.E. Moen, and K.R. Kyvik Organic solvents and the risk of multiple sclerosis Epidemiology 13 6 Nov 2002 718 720
    • (2002) Epidemiology , vol.13 , Issue.6 , pp. 718-720
    • Riise, T.1    Moen, B.E.2    Kyvik, K.R.3
  • 5
    • 48249139449 scopus 로고    scopus 로고
    • Multiple sclerosis: An immune or neurodegenerative disorder?
    • B.D. Trapp, and K.-A. Nave Multiple sclerosis: an immune or neurodegenerative disorder? Annu Rev Neurosci 31 2008 247 269
    • (2008) Annu Rev Neurosci , vol.31 , pp. 247-269
    • Trapp, B.D.1    Nave, K.-A.2
  • 6
    • 34547527078 scopus 로고    scopus 로고
    • Axonal loss and neuroinflammation caused by peroxisome-deficient oligodendrocytes
    • C.M. Kassmann, C. Lappe-Siefke, M. Baes, B. Brügger, A. Mildner, and H.B. Werner Axonal loss and neuroinflammation caused by peroxisome-deficient oligodendrocytes Nat Genet 39 8 Aug 2007 969 976
    • (2007) Nat Genet , vol.39 , Issue.8 , pp. 969-976
    • Kassmann, C.M.1    Lappe-Siefke, C.2    Baes, M.3    Brügger, B.4    Mildner, A.5    Werner, H.B.6
  • 7
    • 74249109341 scopus 로고    scopus 로고
    • The interplay between the immune and central nervous systems in neuronal injury
    • V.W. Yong, and S. Marks The interplay between the immune and central nervous systems in neuronal injury Neurology 74 Suppl. 1 Jan 5 2010 S9 S16
    • (2010) Neurology , vol.74 , Issue.SUPPL. 1
    • Yong, V.W.1    Marks, S.2
  • 8
    • 33646577466 scopus 로고    scopus 로고
    • Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
    • E. Bettelli, Y. Carrier, W. Gao, T. Korn, T.B. Strom, and M. Oukka Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells Nature 441 7090 May 11 2006 235 238
    • (2006) Nature , vol.441 , Issue.7090 , pp. 235-238
    • Bettelli, E.1    Carrier, Y.2    Gao, W.3    Korn, T.4    Strom, T.B.5    Oukka, M.6
  • 9
    • 82955228112 scopus 로고    scopus 로고
    • T(H)17 cytokines in autoimmune neuro-inflammation
    • B. Becher, and B.M. Segal T(H)17 cytokines in autoimmune neuro-inflammation Curr Opin Immunol 23 6 Dec 2011 707 712
    • (2011) Curr Opin Immunol , vol.23 , Issue.6 , pp. 707-712
    • Becher, B.1    Segal, B.M.2
  • 10
    • 77957056123 scopus 로고    scopus 로고
    • In vivo imaging of partially reversible th17 cell-induced neuronal dysfunction in the course of encephalomyelitis
    • V. Siffrin, H. Radbruch, R. Glumm, R. Niesner, M. Paterka, and J. Herz In vivo imaging of partially reversible th17 cell-induced neuronal dysfunction in the course of encephalomyelitis Immunity 33 3 Sep 24 2010 424 436
    • (2010) Immunity , vol.33 , Issue.3 , pp. 424-436
    • Siffrin, V.1    Radbruch, H.2    Glumm, R.3    Niesner, R.4    Paterka, M.5    Herz, J.6
  • 11
    • 1842732224 scopus 로고    scopus 로고
    • Loss of functional suppression by CD4+CD25 + regulatory T cells in patients with multiple sclerosis
    • V. Viglietta, C. Baecher-Allan, H.L. Weiner, and D.A. Hafler Loss of functional suppression by CD4+CD25 + regulatory T cells in patients with multiple sclerosis J Exp Med 199 7 Apr 5 2004 971 979
    • (2004) J Exp Med , vol.199 , Issue.7 , pp. 971-979
    • Viglietta, V.1    Baecher-Allan, C.2    Weiner, H.L.3    Hafler, D.A.4
  • 12
    • 81755173556 scopus 로고    scopus 로고
    • Role of CD8 T cell subsets in the pathogenesis of multiple sclerosis
    • A. Saxena, G. Martin-Blondel, L.T. Mars, and R.S. Liblau Role of CD8 T cell subsets in the pathogenesis of multiple sclerosis FEBS Lett 585 23 Dec 1 2011 3758 3763
    • (2011) FEBS Lett , vol.585 , Issue.23 , pp. 3758-3763
    • Saxena, A.1    Martin-Blondel, G.2    Mars, L.T.3    Liblau, R.S.4
  • 13
    • 39049142995 scopus 로고    scopus 로고
    • B-cell depletion with rituximab in relapsing-remitting multiple sclerosis
    • S.L. Hauser, E. Waubant, D.L. Arnold, T. Vollmer, J. Antel, and R.J. Fox B-cell depletion with rituximab in relapsing-remitting multiple sclerosis N Engl J Med 358 7 Feb 14 2008 676 688
    • (2008) N Engl J Med , vol.358 , Issue.7 , pp. 676-688
    • Hauser, S.L.1    Waubant, E.2    Arnold, D.L.3    Vollmer, T.4    Antel, J.5    Fox, R.J.6
  • 14
    • 81555202418 scopus 로고    scopus 로고
    • Ocrelizumab in relapsing-remitting multiple sclerosis: A phase 2, randomised, placebo-controlled, multicentre trial
    • L. Kappos, D. Li, P.A. Calabresi, P. O'Connor, A. Bar-Or, and F. Barkhof Ocrelizumab in relapsing-remitting multiple sclerosis: a phase 2, randomised, placebo-controlled, multicentre trial Lancet 378 9805 Nov 19 2011 1779 1787
    • (2011) Lancet , vol.378 , Issue.9805 , pp. 1779-1787
    • Kappos, L.1    Li, D.2    Calabresi, P.A.3    O'Connor, P.4    Bar-Or, A.5    Barkhof, F.6
  • 15
    • 34249700046 scopus 로고    scopus 로고
    • Meningeal B-cell follicles in secondary progressive multiple sclerosis associate with early onset of disease and severe cortical pathology
    • R. Magliozzi, O. Howell, A. Vora, B. Serafini, R. Nicholas, and M. Puopolo Meningeal B-cell follicles in secondary progressive multiple sclerosis associate with early onset of disease and severe cortical pathology Brain 130 Pt 4 Apr 2007 1089 1104
    • (2007) Brain , vol.130 , Issue.PART 4 , pp. 1089-1104
    • Magliozzi, R.1    Howell, O.2    Vora, A.3    Serafini, B.4    Nicholas, R.5    Puopolo, M.6
  • 17
    • 82955203797 scopus 로고    scopus 로고
    • B cells in multiple sclerosis: Connecting the dots
    • H.-C. von Büdingen, A. Bar-Or, and S.S. Zamvil B cells in multiple sclerosis: connecting the dots Curr Opin Immunol 23 6 Dec 2011 713 720
    • (2011) Curr Opin Immunol , vol.23 , Issue.6 , pp. 713-720
    • Von Büdingen, H.-C.1    Bar-Or, A.2    Zamvil, S.S.3
  • 18
    • 33645869560 scopus 로고    scopus 로고
    • Dystroglycan is selectively cleaved at the parenchymal basement membrane at sites of leukocyte extravasation in experimental autoimmune encephalomyelitis
    • S. Agrawal, P. Anderson, M. Durbeej, N. van Rooijen, F. Ivars, and G. Opdenakker Dystroglycan is selectively cleaved at the parenchymal basement membrane at sites of leukocyte extravasation in experimental autoimmune encephalomyelitis J Exp Med 203 4 Apr 17 2006 1007 1019
    • (2006) J Exp Med , vol.203 , Issue.4 , pp. 1007-1019
    • Agrawal, S.1    Anderson, P.2    Durbeej, M.3    Van Rooijen, N.4    Ivars, F.5    Opdenakker, G.6
  • 19
    • 36849030749 scopus 로고    scopus 로고
    • MMPs in the central nervous system: Where the good guys go bad
    • S.M. Agrawal, L. Lau, and V.W. Yong MMPs in the central nervous system: where the good guys go bad Semin Cell Dev Biol 19 1 Feb 2008 42 51
    • (2008) Semin Cell Dev Biol , vol.19 , Issue.1 , pp. 42-51
    • Agrawal, S.M.1    Lau, L.2    Yong, V.W.3
  • 20
    • 78651515693 scopus 로고    scopus 로고
    • EMMPRIN: A novel regulator of leukocyte transmigration into the CNS in multiple sclerosis and experimental autoimmune encephalomyelitis
    • S.M. Agrawal, C. Silva, W.W. Tourtellotte, and V.W. Yong EMMPRIN: a novel regulator of leukocyte transmigration into the CNS in multiple sclerosis and experimental autoimmune encephalomyelitis J Neurosci 31 2 Jan 12 2011 669 677
    • (2011) J Neurosci , vol.31 , Issue.2 , pp. 669-677
    • Agrawal, S.M.1    Silva, C.2    Tourtellotte, W.W.3    Yong, V.W.4
  • 21
    • 79953761792 scopus 로고    scopus 로고
    • A reversible form of axon damage in experimental autoimmune encephalomyelitis and multiple sclerosis
    • I. Nikić, D. Merkler, C. Sorbara, M. Brinkoetter, M. Kreutzfeldt, and F.M. Bareyre A reversible form of axon damage in experimental autoimmune encephalomyelitis and multiple sclerosis Nat Med 17 4 Apr 2011 495 499
    • (2011) Nat Med , vol.17 , Issue.4 , pp. 495-499
    • Nikić, I.1    Merkler, D.2    Sorbara, C.3    Brinkoetter, M.4    Kreutzfeldt, M.5    Bareyre, F.M.6
  • 22
    • 0029569108 scopus 로고
    • Migrant studies in multiple sclerosis
    • C.R. Gale, and C.N. Martyn Migrant studies in multiple sclerosis Prog Neurobiol 47 4-5 Dec 1995 425 448
    • (1995) Prog Neurobiol , vol.47 , Issue.45 , pp. 425-448
    • Gale, C.R.1    Martyn, C.N.2
  • 23
    • 0013950284 scopus 로고
    • Risk of multiple sclerosis related to age at immigration to Israel
    • M. Alter, U. Leibowitz, and J. Speer Risk of multiple sclerosis related to age at immigration to Israel Arch Neurol 15 3 Sep 1966 234 237
    • (1966) Arch Neurol , vol.15 , Issue.3 , pp. 234-237
    • Alter, M.1    Leibowitz, U.2    Speer, J.3
  • 24
    • 0018377382 scopus 로고
    • Multiple sclerosis in the Faroe Islands: I. Clinical and epidemiological features
    • J.F. Kurtzke, and K. Hyllested Multiple sclerosis in the Faroe Islands: I. Clinical and epidemiological features Ann Neurol 5 1 Jan 1979 6 21
    • (1979) Ann Neurol , vol.5 , Issue.1 , pp. 6-21
    • Kurtzke, J.F.1    Hyllested, K.2
  • 25
    • 79951549055 scopus 로고    scopus 로고
    • Multiple sclerosis: Variation of incidence of onset over time in the Faroe Islands
    • P. Joensen Multiple sclerosis: variation of incidence of onset over time in the Faroe Islands Mult Scler 17 2 Feb 2011 241 244
    • (2011) Mult Scler , vol.17 , Issue.2 , pp. 241-244
    • Joensen, P.1
  • 26
    • 0019177933 scopus 로고
    • Multiple sclerosis in the Orkney and Shetland Islands. II: The search for an exogenous aetiology
    • D.C. Poskanzer, J.L. Sheridan, L.B. Prenney, and A.M. Walker Multiple sclerosis in the Orkney and Shetland Islands. II: The search for an exogenous aetiology J Epidemiol Community Health 34 4 Dec 1980 240 252
    • (1980) J Epidemiol Community Health , vol.34 , Issue.4 , pp. 240-252
    • Poskanzer, D.C.1    Sheridan, J.L.2    Prenney, L.B.3    Walker, A.M.4
  • 27
    • 0028297805 scopus 로고
    • Environmental risk factors and multiple sclerosis: A community-based, case-control study in the province of Ferrara, Italy
    • I. Casetta, E. Granieri, S. Malagù, M.R. Tola, E. Paolino, and L.M. Caniatti Environmental risk factors and multiple sclerosis: a community-based, case-control study in the province of Ferrara, Italy Neuroepidemiology 13 3 1994 120 128
    • (1994) Neuroepidemiology , vol.13 , Issue.3 , pp. 120-128
    • Casetta, I.1    Granieri, E.2    Malagù, S.3    Tola, M.R.4    Paolino, E.5    Caniatti, L.M.6
  • 28
    • 0022632083 scopus 로고
    • Incidence of multiple sclerosis in Macomer, Sardinia, 1912-1981: Onset of the disease after 1950
    • G. Rosati, I. Aiello, E. Granieri, M.I. Pirastru, S. Becciu, and G. Demontis Incidence of multiple sclerosis in Macomer, Sardinia, 1912-1981: onset of the disease after 1950 Neurology 36 1 Jan 1986 14 19
    • (1986) Neurology , vol.36 , Issue.1 , pp. 14-19
    • Rosati, G.1    Aiello, I.2    Granieri, E.3    Pirastru, M.I.4    Becciu, S.5    Demontis, G.6
  • 29
    • 34247590137 scopus 로고    scopus 로고
    • Environmental risk factors for multiple sclerosis. Part I: The role of infection
    • A. Ascherio, and K.L. Munger Environmental risk factors for multiple sclerosis. Part I: the role of infection Ann Neurol 61 4 Apr 2007 288 299
    • (2007) Ann Neurol , vol.61 , Issue.4 , pp. 288-299
    • Ascherio, A.1    Munger, K.L.2
  • 30
    • 77958600548 scopus 로고    scopus 로고
    • An updated meta-analysis of risk of multiple sclerosis following infectious mononucleosis
    • cited 2011 Nov 1
    • A.E. Handel, A.J. Williamson, G. Disanto, L. Handunnetthi, G. Giovannoni, and S.V. Ramagopalan An updated meta-analysis of risk of multiple sclerosis following infectious mononucleosis PLoS ONE [Internet] 5 9 2010 [cited 2011 Nov 1; Available from: http://www.ncbi.nlm.nih.gov/pubmed/20824132 ]
    • (2010) PLoS ONE [Internet] , vol.5 , Issue.9
    • Handel, A.E.1    Williamson, A.J.2    Disanto, G.3    Handunnetthi, L.4    Giovannoni, G.5    Ramagopalan, S.V.6
  • 32
    • 68249150707 scopus 로고    scopus 로고
    • Humoral immune response to EBV in multiple sclerosis is associated with disease activity on MRI
    • R.A. Farrell, D. Antony, G.R. Wall, D.A. Clark, L. Fisniku, and J. Swanton Humoral immune response to EBV in multiple sclerosis is associated with disease activity on MRI Neurology 73 1 Jul 7 2009 32 38
    • (2009) Neurology , vol.73 , Issue.1 , pp. 32-38
    • Farrell, R.A.1    Antony, D.2    Wall, G.R.3    Clark, D.A.4    Fisniku, L.5    Swanton, J.6
  • 33
    • 77949344541 scopus 로고    scopus 로고
    • Elevated Epstein-Barr virus-encoded nuclear antigen-1 immune responses predict conversion to multiple sclerosis
    • J.D. Lünemann, M. Tintoré, B. Messmer, T. Strowig, A. Rovira, and H. Perkal Elevated Epstein-Barr virus-encoded nuclear antigen-1 immune responses predict conversion to multiple sclerosis Ann Neurol 67 2 Feb 2010 159 169
    • (2010) Ann Neurol , vol.67 , Issue.2 , pp. 159-169
    • Lünemann, J.D.1    Tintoré, M.2    Messmer, B.3    Strowig, T.4    Rovira, A.5    Perkal, H.6
  • 34
    • 78650455250 scopus 로고    scopus 로고
    • Anti-EBNA-1 IgG is not a reliable marker of multiple sclerosis clinical disease activity
    • G. Ingram, J.J. Bugert, S. Loveless, and N.P. Robertson Anti-EBNA-1 IgG is not a reliable marker of multiple sclerosis clinical disease activity Eur J Neurol 17 11 Nov 2010 1386 1389
    • (2010) Eur J Neurol , vol.17 , Issue.11 , pp. 1386-1389
    • Ingram, G.1    Bugert, J.J.2    Loveless, S.3    Robertson, N.P.4
  • 35
    • 77949275878 scopus 로고    scopus 로고
    • Intrathecal antibody production against Epstein-Barr and other neurotropic viruses in pediatric and adult onset multiple sclerosis
    • D. Pohl, K. Rostasy, C. Jacobi, P. Lange, R. Nau, and B. Krone Intrathecal antibody production against Epstein-Barr and other neurotropic viruses in pediatric and adult onset multiple sclerosis J Neurol 257 2 Feb 2010 212 216
    • (2010) J Neurol , vol.257 , Issue.2 , pp. 212-216
    • Pohl, D.1    Rostasy, K.2    Jacobi, C.3    Lange, P.4    Nau, R.5    Krone, B.6
  • 36
    • 79954605834 scopus 로고    scopus 로고
    • Intrathecal EBV antibodies are part of the polyspecific immune response in multiple sclerosis
    • C. Otto, A. Oltmann, A. Stein, K. Frenzel, J. Schroeter, and P. Habbel Intrathecal EBV antibodies are part of the polyspecific immune response in multiple sclerosis Neurology 76 15 Apr 12 2011 1316 1321
    • (2011) Neurology , vol.76 , Issue.15 , pp. 1316-1321
    • Otto, C.1    Oltmann, A.2    Stein, A.3    Frenzel, K.4    Schroeter, J.5    Habbel, P.6
  • 38
    • 17644396349 scopus 로고    scopus 로고
    • Immunology of multiple sclerosis
    • M. Sospedra, and R. Martin Immunology of multiple sclerosis Annu Rev Immunol 23 2005 683 747
    • (2005) Annu Rev Immunol , vol.23 , pp. 683-747
    • Sospedra, M.1    Martin, R.2
  • 40
    • 83655191550 scopus 로고    scopus 로고
    • Molecular mimicry as an inducing trigger for CNS autoimmune demyelinating disease
    • E.M.L. Chastain, and S.D. Miller Molecular mimicry as an inducing trigger for CNS autoimmune demyelinating disease Immunol Rev 245 1 Jan 2012 227 238
    • (2012) Immunol Rev , vol.245 , Issue.1 , pp. 227-238
    • Chastain, E.M.L.1    Miller, S.D.2
  • 41
    • 0030030561 scopus 로고    scopus 로고
    • Myelin basic protein and human coronavirus 229E cross-reactive T cells in multiple sclerosis
    • P.J. Talbot, J.S. Paquette, C. Ciurli, J.P. Antel, and F. Ouellet Myelin basic protein and human coronavirus 229E cross-reactive T cells in multiple sclerosis Ann Neurol 39 2 Feb 1996 233 240
    • (1996) Ann Neurol , vol.39 , Issue.2 , pp. 233-240
    • Talbot, P.J.1    Paquette, J.S.2    Ciurli, C.3    Antel, J.P.4    Ouellet, F.5
  • 42
    • 84859241576 scopus 로고    scopus 로고
    • Cross-reactivity of autoreactive T cells with MBP and viral antigens in patients with MS
    • W. Cheng, Y. Ma, F. Gong, C. Hu, L. Qian, and Q. Huang Cross-reactivity of autoreactive T cells with MBP and viral antigens in patients with MS Front Biosci 17 2012 1648 1658
    • (2012) Front Biosci , vol.17 , pp. 1648-1658
    • Cheng, W.1    Ma, Y.2    Gong, F.3    Hu, C.4    Qian, L.5    Huang, Q.6
  • 43
    • 0036793245 scopus 로고    scopus 로고
    • A functional and structural basis for TCR cross-reactivity in multiple sclerosis
    • H.L.E. Lang, H. Jacobsen, S. Ikemizu, C. Andersson, K. Harlos, and L. Madsen A functional and structural basis for TCR cross-reactivity in multiple sclerosis Nat Immunol 3 10 Oct 2002 940 943
    • (2002) Nat Immunol , vol.3 , Issue.10 , pp. 940-943
    • Lang, H.L.E.1    Jacobsen, H.2    Ikemizu, S.3    Andersson, C.4    Harlos, K.5    Madsen, L.6
  • 44
    • 77954725231 scopus 로고    scopus 로고
    • Epstein-Barr virus latent infection and BAFF expression in B cells in the multiple sclerosis brain: Implications for viral persistence and intrathecal B-cell activation
    • B. Serafini, M. Severa, S. Columba-Cabezas, B. Rosicarelli, C. Veroni, and G. Chiappetta Epstein-Barr virus latent infection and BAFF expression in B cells in the multiple sclerosis brain: implications for viral persistence and intrathecal B-cell activation J Neuropathol Exp Neurol 69 7 Jul 2010 677 693
    • (2010) J Neuropathol Exp Neurol , vol.69 , Issue.7 , pp. 677-693
    • Serafini, B.1    Severa, M.2    Columba-Cabezas, S.3    Rosicarelli, B.4    Veroni, C.5    Chiappetta, G.6
  • 45
    • 82655171685 scopus 로고    scopus 로고
    • Translational Mini-Review Series on B cell subsets in disease. B cells in multiple sclerosis: Drivers of disease pathogenesis and Trojan horse for Epstein-Barr virus entry to the central nervous system?
    • U.-C. Meier, G. Giovannoni, J.S. Tzartos, and G. Khan Translational Mini-Review Series on B cell subsets in disease. B cells in multiple sclerosis: drivers of disease pathogenesis and Trojan horse for Epstein-Barr virus entry to the central nervous system? Clin Exp Immunol 167 1 Jan 2012 1 6
    • (2012) Clin Exp Immunol , vol.167 , Issue.1 , pp. 1-6
    • Meier, U.-C.1    Giovannoni, G.2    Tzartos, J.S.3    Khan, G.4
  • 46
    • 82655181512 scopus 로고    scopus 로고
    • Combinatorial antibody library from multiple sclerosis patients reveals antibodies that cross-react with myelin basic protein and EBV antigen
    • A.G. Gabibov, A.A. Belogurov Jr., Y.A. Lomakin, M.Y. Zakharova, M.E. Avakyan, and V.V. Dubrovskaya Combinatorial antibody library from multiple sclerosis patients reveals antibodies that cross-react with myelin basic protein and EBV antigen FASEB J 25 12 Dec 2011 4211 4221
    • (2011) FASEB J , vol.25 , Issue.12 , pp. 4211-4221
    • Gabibov, A.G.1    Belogurov Jr., A.A.2    Lomakin, Y.A.3    Zakharova, M.Y.4    Avakyan, M.E.5    Dubrovskaya, V.V.6
  • 47
    • 84860330754 scopus 로고    scopus 로고
    • HLA-B7-restricted EBV-specific CD8 + T cells are dysregulated in multiple sclerosis
    • S. Jilek, M. Schluep, A. Harari, M. Canales, A. Lysandropoulos, and A. Zekeridou HLA-B7-restricted EBV-specific CD8 + T cells are dysregulated in multiple sclerosis J Immunol 188 9 May 1 2012 4671 4680
    • (2012) J Immunol , vol.188 , Issue.9 , pp. 4671-4680
    • Jilek, S.1    Schluep, M.2    Harari, A.3    Canales, M.4    Lysandropoulos, A.5    Zekeridou, A.6
  • 48
    • 84867779322 scopus 로고    scopus 로고
    • CD8 + T-cell deficiency, Epstein-Barr Virus infection, vitamin D deficiency, and steps to autoimmunity: A unifying hypothesis
    • M.P. Pender CD8 + T-cell deficiency, Epstein-Barr Virus infection, vitamin D deficiency, and steps to autoimmunity: a unifying hypothesis Autoimmune Dis 2012 2012 189096
    • (2012) Autoimmune Dis , vol.2012 , pp. 189096
    • Pender, M.P.1
  • 49
    • 33847679709 scopus 로고    scopus 로고
    • Association between parasite infection and immune responses in multiple sclerosis
    • J. Correale, and M. Farez Association between parasite infection and immune responses in multiple sclerosis Ann Neurol 61 2 Feb 2007 97 108
    • (2007) Ann Neurol , vol.61 , Issue.2 , pp. 97-108
    • Correale, J.1    Farez, M.2
  • 50
    • 79953306426 scopus 로고    scopus 로고
    • The impact of parasite infections on the course of multiple sclerosis
    • J. Correale, and M.F. Farez The impact of parasite infections on the course of multiple sclerosis J Neuroimmunol 233 1-2 Apr 2011 6 11
    • (2011) J Neuroimmunol , vol.233 , Issue.12 , pp. 6-11
    • Correale, J.1    Farez, M.F.2
  • 51
    • 79953299582 scopus 로고    scopus 로고
    • Probiotic helminth administration in relapsing-remitting multiple sclerosis: A phase 1 study
    • J. Fleming, A. Isaak, J. Lee, C. Luzzio, M. Carrithers, and T. Cook Probiotic helminth administration in relapsing-remitting multiple sclerosis: a phase 1 study Mult Scler 17 6 Jun 2011 743 754
    • (2011) Mult Scler , vol.17 , Issue.6 , pp. 743-754
    • Fleming, J.1    Isaak, A.2    Lee, J.3    Luzzio, C.4    Carrithers, M.5    Cook, T.6
  • 52
    • 51549118693 scopus 로고    scopus 로고
    • Helminth infections associated with multiple sclerosis induce regulatory B cells
    • J. Correale, M. Farez, and G. Razzitte Helminth infections associated with multiple sclerosis induce regulatory B cells Ann Neurol 64 2 Aug 2008 187 199
    • (2008) Ann Neurol , vol.64 , Issue.2 , pp. 187-199
    • Correale, J.1    Farez, M.2    Razzitte, G.3
  • 53
    • 0035400165 scopus 로고    scopus 로고
    • Cigarette smoking and incidence of multiple sclerosis
    • M.A. Hernán, M.J. Olek, and A. Ascherio Cigarette smoking and incidence of multiple sclerosis Am J Epidemiol 154 1 Jul 1 2001 69 74
    • (2001) Am J Epidemiol , vol.154 , Issue.1 , pp. 69-74
    • Hernán, M.A.1    Olek, M.J.2    Ascherio, A.3
  • 54
    • 34848909001 scopus 로고    scopus 로고
    • Parental smoking at home and the risk of childhood-onset multiple sclerosis in children
    • Y. Mikaeloff, G. Caridade, M. Tardieu, and S. Suissa Parental smoking at home and the risk of childhood-onset multiple sclerosis in children Brain 130 Pt 10 Oct 2007 2589 2595
    • (2007) Brain , vol.130 , Issue.PART 10 , pp. 2589-2595
    • Mikaeloff, Y.1    Caridade, G.2    Tardieu, M.3    Suissa, S.4
  • 55
    • 79959497749 scopus 로고    scopus 로고
    • Exposure to environmental tobacco smoke is associated with increased risk for multiple sclerosis
    • A. Hedström, M. Bäärnhielm, T. Olsson, and L. Alfredsson Exposure to environmental tobacco smoke is associated with increased risk for multiple sclerosis Mult Scler 17 7 Jul 2011 788 793
    • (2011) Mult Scler , vol.17 , Issue.7 , pp. 788-793
    • Hedström, A.1    Bäärnhielm, M.2    Olsson, T.3    Alfredsson, L.4
  • 56
    • 57749091110 scopus 로고    scopus 로고
    • Smoking is a risk factor for early conversion to clinically definite multiple sclerosis
    • F. Di Pauli, M. Reindl, R. Ehling, F. Schautzer, C. Gneiss, and A. Lutterotti Smoking is a risk factor for early conversion to clinically definite multiple sclerosis Mult Scler 14 8 Sep 2008 1026 1030
    • (2008) Mult Scler , vol.14 , Issue.8 , pp. 1026-1030
    • Di Pauli, F.1    Reindl, M.2    Ehling, R.3    Schautzer, F.4    Gneiss, C.5    Lutterotti, A.6
  • 57
    • 69449102477 scopus 로고    scopus 로고
    • Smoking is associated with increased lesion volumes and brain atrophy in multiple sclerosis
    • R. Zivadinov, B. Weinstock-Guttman, K. Hashmi, N. Abdelrahman, M. Stosic, and M. Dwyer Smoking is associated with increased lesion volumes and brain atrophy in multiple sclerosis Neurology 73 7 Aug 18 2009 504 510
    • (2009) Neurology , vol.73 , Issue.7 , pp. 504-510
    • Zivadinov, R.1    Weinstock-Guttman, B.2    Hashmi, K.3    Abdelrahman, N.4    Stosic, M.5    Dwyer, M.6
  • 59
    • 35148819256 scopus 로고    scopus 로고
    • Cigarette smoking and progression in multiple sclerosis
    • M. Koch, A. van Harten, M. Uyttenboogaart, and J. De Keyser Cigarette smoking and progression in multiple sclerosis Neurology 69 15 Oct 9 2007 1515 1520
    • (2007) Neurology , vol.69 , Issue.15 , pp. 1515-1520
    • Koch, M.1    Van Harten, A.2    Uyttenboogaart, M.3    De Keyser, J.4
  • 60
    • 20444495271 scopus 로고    scopus 로고
    • Cigarette smoking and the progression of multiple sclerosis
    • M.A. Hernán, S.S. Jick, G. Logroscino, M.J. Olek, A. Ascherio, and H. Jick Cigarette smoking and the progression of multiple sclerosis Brain 128 Pt 6 Jun 2005 1461 1465
    • (2005) Brain , vol.128 , Issue.PART 6 , pp. 1461-1465
    • Hernán, M.A.1    Jick, S.S.2    Logroscino, G.3    Olek, M.J.4    Ascherio, A.5    Jick, H.6
  • 61
    • 67349263039 scopus 로고    scopus 로고
    • Smoking is associated with progressive disease course and increased progression in clinical disability in a prospective cohort of people with multiple sclerosis
    • F. Pittas, A.-L. Ponsonby, I.A.F. van der Mei, B.V. Taylor, L. Blizzard, and P. Groom Smoking is associated with progressive disease course and increased progression in clinical disability in a prospective cohort of people with multiple sclerosis J Neurol 256 4 2009 577 585
    • (2009) J Neurol , vol.256 , Issue.4 , pp. 577-585
    • Pittas, F.1    Ponsonby, A.-L.2    Van Der Mei, I.A.F.3    Taylor, B.V.4    Blizzard, L.5    Groom, P.6
  • 63
    • 79952138032 scopus 로고    scopus 로고
    • Smoking and two human leukocyte antigen genes interact to increase the risk for multiple sclerosis
    • A.K. Hedström, E. Sundqvist, M. Bäärnhielm, N. Nordin, J. Hillert, and I. Kockum Smoking and two human leukocyte antigen genes interact to increase the risk for multiple sclerosis Brain 134 Pt 3 Mar 2011 653 664
    • (2011) Brain , vol.134 , Issue.PART 3 , pp. 653-664
    • Hedström, A.K.1    Sundqvist, E.2    Bäärnhielm, M.3    Nordin, N.4    Hillert, J.5    Kockum, I.6
  • 64
    • 42649095378 scopus 로고    scopus 로고
    • Control of T(reg) and T(H)17 cell differentiation by the aryl hydrocarbon receptor
    • F.J. Quintana, A.S. Basso, A.H. Iglesias, T. Korn, M.F. Farez, and E. Bettelli Control of T(reg) and T(H)17 cell differentiation by the aryl hydrocarbon receptor Nature 453 7191 May 1 2008 65 71
    • (2008) Nature , vol.453 , Issue.7191 , pp. 65-71
    • Quintana, F.J.1    Basso, A.S.2    Iglesias, A.H.3    Korn, T.4    Farez, M.F.5    Bettelli, E.6
  • 65
    • 78650085459 scopus 로고    scopus 로고
    • Smoking and matrix metalloproteinases, neutrophil elastase and myeloperoxidase in chronic periodontitis
    • O. Ozçaka, N. Biçakci, P. Pussinen, T. Sorsa, T. Köse, and N. Buduneli Smoking and matrix metalloproteinases, neutrophil elastase and myeloperoxidase in chronic periodontitis Oral Dis 17 1 Jan 2011 68 76
    • (2011) Oral Dis , vol.17 , Issue.1 , pp. 68-76
    • Ozçaka, O.1    Biçakci, N.2    Pussinen, P.3    Sorsa, T.4    Köse, T.5    Buduneli, N.6
  • 66
    • 80052610245 scopus 로고    scopus 로고
    • Latitude is significantly associated with the prevalence of multiple sclerosis: A meta-analysis
    • S. Simpson Jr., L. Blizzard, P. Otahal, I. Van der Mei, and B. Taylor Latitude is significantly associated with the prevalence of multiple sclerosis: a meta-analysis J Neurol Neurosurg Psychiatry 82 10 2011 1132 1141
    • (2011) J Neurol Neurosurg Psychiatry , vol.82 , Issue.10 , pp. 1132-1141
    • Simpson Jr., S.1    Blizzard, L.2    Otahal, P.3    Van Der Mei, I.4    Taylor, B.5
  • 67
    • 77952314178 scopus 로고    scopus 로고
    • Vitamin D and multiple sclerosis
    • A. Ascherio, K.L. Munger, and K.C. Simon Vitamin D and multiple sclerosis Lancet Neurol 9 6 Jun 2010 599 612
    • (2010) Lancet Neurol , vol.9 , Issue.6 , pp. 599-612
    • Ascherio, A.1    Munger, K.L.2    Simon, K.C.3
  • 68
    • 0042634407 scopus 로고    scopus 로고
    • Past exposure to sun, skin phenotype, and risk of multiple sclerosis: Case-control study
    • I.A.F. van der Mei, A.-L. Ponsonby, T. Dwyer, L. Blizzard, R. Simmons, and B.V. Taylor Past exposure to sun, skin phenotype, and risk of multiple sclerosis: case-control study BMJ 327 7410 2003 316
    • (2003) BMJ , vol.327 , Issue.7410 , pp. 316
    • Van Der Mei, I.A.F.1    Ponsonby, A.-L.2    Dwyer, T.3    Blizzard, L.4    Simmons, R.5    Taylor, B.V.6
  • 69
    • 33845720114 scopus 로고    scopus 로고
    • Serum 25-hydroxyvitamin D levels and risk of multiple sclerosis
    • K.L. Munger, L.I. Levin, B.W. Hollis, N.S. Howard, and A. Ascherio Serum 25-hydroxyvitamin D levels and risk of multiple sclerosis JAMA 296 23 Dec 20 2006 2832 2838
    • (2006) JAMA , vol.296 , Issue.23 , pp. 2832-2838
    • Munger, K.L.1    Levin, L.I.2    Hollis, B.W.3    Howard, N.S.4    Ascherio, A.5
  • 71
    • 0028106832 scopus 로고
    • High prevalence of vitamin D deficiency and reduced bone mass in multiple sclerosis
    • J. Nieves, F. Cosman, J. Herbert, V. Shen, and R. Lindsay High prevalence of vitamin D deficiency and reduced bone mass in multiple sclerosis Neurology 44 9 Sep 1994 1687 1692
    • (1994) Neurology , vol.44 , Issue.9 , pp. 1687-1692
    • Nieves, J.1    Cosman, F.2    Herbert, J.3    Shen, V.4    Lindsay, R.5
  • 72
    • 59249106554 scopus 로고    scopus 로고
    • Association of vitamin D metabolite levels with relapse rate and disability in multiple sclerosis
    • J. Smolders, P. Menheere, A. Kessels, J. Damoiseaux, and R. Hupperts Association of vitamin D metabolite levels with relapse rate and disability in multiple sclerosis Mult Scler 14 9 Nov 2008 1220 1224
    • (2008) Mult Scler , vol.14 , Issue.9 , pp. 1220-1224
    • Smolders, J.1    Menheere, P.2    Kessels, A.3    Damoiseaux, J.4    Hupperts, R.5
  • 73
    • 77955291052 scopus 로고    scopus 로고
    • Higher 25-hydroxyvitamin D is associated with lower relapse risk in multiple sclerosis
    • S. Simpson, B. Taylor, L. Blizzard, A.-L. Ponsonby, F. Pittas, and H. Tremlett Higher 25-hydroxyvitamin D is associated with lower relapse risk in multiple sclerosis Ann Neurol 68 2 Aug 2010 193 203
    • (2010) Ann Neurol , vol.68 , Issue.2 , pp. 193-203
    • Simpson, S.1    Taylor, B.2    Blizzard, L.3    Ponsonby, A.-L.4    Pittas, F.5    Tremlett, H.6
  • 74
    • 77951713604 scopus 로고    scopus 로고
    • Vitamin D status is associated with relapse rate in pediatric-onset multiple sclerosis
    • E.M. Mowry, L.B. Krupp, M. Milazzo, D. Chabas, J.B. Strober, and A.L. Belman Vitamin D status is associated with relapse rate in pediatric-onset multiple sclerosis Ann Neurol 67 5 May 2010 618 624
    • (2010) Ann Neurol , vol.67 , Issue.5 , pp. 618-624
    • Mowry, E.M.1    Krupp, L.B.2    Milazzo, M.3    Chabas, D.4    Strober, J.B.5    Belman, A.L.6
  • 75
    • 77953328331 scopus 로고    scopus 로고
    • A phase I/II dose-escalation trial of vitamin D3 and calcium in multiple sclerosis
    • J.M. Burton, S. Kimball, R. Vieth, A. Bar-Or, H.-M. Dosch, and R. Cheung A phase I/II dose-escalation trial of vitamin D3 and calcium in multiple sclerosis Neurology 74 23 Jun 8 2010 1852 1859
    • (2010) Neurology , vol.74 , Issue.23 , pp. 1852-1859
    • Burton, J.M.1    Kimball, S.2    Vieth, R.3    Bar-Or, A.4    Dosch, H.-M.5    Cheung, R.6
  • 76
    • 80052098478 scopus 로고    scopus 로고
    • Modulation of the immune system by UV radiation: More than just the effects of vitamin D?
    • P.H. Hart, S. Gorman, and J.J. Finlay-Jones Modulation of the immune system by UV radiation: more than just the effects of vitamin D? Nat Rev Immunol 11 9 Sep 2011 584 596
    • (2011) Nat Rev Immunol , vol.11 , Issue.9 , pp. 584-596
    • Hart, P.H.1    Gorman, S.2    Finlay-Jones, J.J.3
  • 78
    • 80051684615 scopus 로고    scopus 로고
    • Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis
    • S. Sawcer, G. Hellenthal, M. Pirinen, C.C.A. Spencer, N.A. Patsopoulos, and L. Moutsianas Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis Nature 476 7359 Aug 11 2011 214 219
    • (2011) Nature , vol.476 , Issue.7359 , pp. 214-219
    • Sawcer, S.1    Hellenthal, G.2    Pirinen, M.3    Spencer, C.C.A.4    Patsopoulos, N.A.5    Moutsianas, L.6
  • 79
    • 61449102631 scopus 로고    scopus 로고
    • Expression of the multiple sclerosis-associated MHC class II Allele HLA-DRB1*1501 is regulated by vitamin D
    • S.V. Ramagopalan, N.J. Maugeri, L. Handunnetthi, M.R. Lincoln, S.-M. Orton, and D.A. Dyment Expression of the multiple sclerosis-associated MHC class II Allele HLA-DRB1*1501 is regulated by vitamin D PLoS Genet 5 2 Feb 2009 e1000369
    • (2009) PLoS Genet , vol.5 , Issue.2 , pp. 1000369
    • Ramagopalan, S.V.1    Maugeri, N.J.2    Handunnetthi, L.3    Lincoln, M.R.4    Orton, S.-M.5    Dyment, D.A.6
  • 80
    • 61449181171 scopus 로고    scopus 로고
    • 1,25-dihydroxyvitamin D3 is an autonomous regulator of the transcriptional changes leading to a tolerogenic dendritic cell phenotype
    • L. Széles, G. Keresztes, D. Töröcsik, Z. Balajthy, L. Krenács, and S. Póliska 1,25-dihydroxyvitamin D3 is an autonomous regulator of the transcriptional changes leading to a tolerogenic dendritic cell phenotype J Immunol 182 4 Feb 15 2009 2074 2083
    • (2009) J Immunol , vol.182 , Issue.4 , pp. 2074-2083
    • Széles, L.1    Keresztes, G.2    Töröcsik, D.3    Balajthy, Z.4    Krenács, L.5    Póliska, S.6
  • 81
    • 66549129834 scopus 로고    scopus 로고
    • Immunomodulatory effects of Vitamin D in multiple sclerosis
    • J. Correale, M.C. Ysrraelit, and M.I. Gaitán Immunomodulatory effects of Vitamin D in multiple sclerosis Brain 132 Pt 5 May 2009 1146 1160
    • (2009) Brain , vol.132 , Issue.PART 5 , pp. 1146-1160
    • Correale, J.1    Ysrraelit, M.C.2    Gaitán, M.I.3
  • 82
    • 79956287488 scopus 로고    scopus 로고
    • Predominance of Th2 polarization by Vitamin D through a STAT6-dependent mechanism
    • S. Sloka, C. Silva, J. Wang, and V.W. Yong Predominance of Th2 polarization by Vitamin D through a STAT6-dependent mechanism J Neuroinflammation 8 2011 56
    • (2011) J Neuroinflammation , vol.8 , pp. 56
    • Sloka, S.1    Silva, C.2    Wang, J.3    Yong, V.W.4
  • 83
    • 60649109332 scopus 로고    scopus 로고
    • 1Alpha,25-dihydroxyvitamin D3 inhibits CD40L-induced pro-inflammatory and immunomodulatory activity in human monocytes
    • C. Almerighi, A. Sinistro, A. Cavazza, C. Ciaprini, G. Rocchi, and A. Bergamini 1Alpha,25-dihydroxyvitamin D3 inhibits CD40L-induced pro-inflammatory and immunomodulatory activity in human monocytes Cytokine 45 3 Mar 2009 190 197
    • (2009) Cytokine , vol.45 , Issue.3 , pp. 190-197
    • Almerighi, C.1    Sinistro, A.2    Cavazza, A.3    Ciaprini, C.4    Rocchi, G.5    Bergamini, A.6
  • 84
    • 0025732356 scopus 로고
    • 1,25-dihydroxyvitamin D3 prevents the in vivo induction of murine experimental autoimmune encephalomyelitis
    • J.M. Lemire, and D.C. Archer 1,25-dihydroxyvitamin D3 prevents the in vivo induction of murine experimental autoimmune encephalomyelitis J Clin Invest 87 3 Mar 1991 1103 1107
    • (1991) J Clin Invest , vol.87 , Issue.3 , pp. 1103-1107
    • Lemire, J.M.1    Archer, D.C.2
  • 85
    • 0029821239 scopus 로고    scopus 로고
    • 1,25-Dihydroxyvitamin D3 reversibly blocks the progression of relapsing encephalomyelitis, a model of multiple sclerosis
    • M.T. Cantorna, C.E. Hayes, and H.F. DeLuca 1,25-Dihydroxyvitamin D3 reversibly blocks the progression of relapsing encephalomyelitis, a model of multiple sclerosis Proc Natl Acad Sci U S A 93 15 Jul 23 1996 7861 7864
    • (1996) Proc Natl Acad Sci U S A , vol.93 , Issue.15 , pp. 7861-7864
    • Cantorna, M.T.1    Hayes, C.E.2    Deluca, H.F.3
  • 86
    • 81255135921 scopus 로고    scopus 로고
    • Vitamin D in the healthy and inflamed central nervous system: Access and function
    • J. Smolders, S.M. Moen, J. Damoiseaux, I. Huitinga, and T. Holmoy Vitamin D in the healthy and inflamed central nervous system: access and function J Neurol Sci 311 1-2 Dec 15 2011 37 43
    • (2011) J Neurol Sci , vol.311 , Issue.12 , pp. 37-43
    • Smolders, J.1    Moen, S.M.2    Damoiseaux, J.3    Huitinga, I.4    Holmoy, T.5
  • 88
    • 0035144882 scopus 로고    scopus 로고
    • Vitamin D hormone confers neuroprotection in parallel with downregulation of L-type calcium channel expression in hippocampal neurons
    • L.D. Brewer, V. Thibault, K.C. Chen, M.C. Langub, P.W. Landfield, and N.M. Porter Vitamin D hormone confers neuroprotection in parallel with downregulation of L-type calcium channel expression in hippocampal neurons J Neurosci 21 1 2001 Jan 1 98 108
    • (2001) J Neurosci , vol.21 , Issue.1 , pp. 98-108
    • Brewer, L.D.1    Thibault, V.2    Chen, K.C.3    Langub, M.C.4    Landfield, P.W.5    Porter, N.M.6


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