Intrathecal antibody production against Epstein-Barr and other neurotropic viruses in pediatric and adult onset multiple sclerosis

Journal of Neurology

Volumn 257, Issue 2, 2010, Pages 212-216

  Pohl, Daniela ^a   Rostasy, Kevin ^b   Jacobi, Christian ^c   Lange, Peter ^d   Nau, Roland ^d,e   Krone, Bernd ^d,f   Hanefeld, Folker ^d  

^a CHILDREN S HOSPITAL OF EASTERN ONTARIO   (Canada)

^b INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^c UNIVERSITY OF HEIDELBERG   (Germany)

^d UNIVERSITY OF GÖTTINGEN   (Germany)

^e Sleep Laboratory   (Germany)

^f Laboratory Medicine Institute Kassel   (Germany)

Author keywords

CNS humoral immune response; Epstein Barr virus; Intrathecal immunoglobulin production; Multiple sclerosis; Neurotropic viruses

Indexed keywords

ANTIBODY; DNA; EPSTEIN BARR VIRUS ANTIGEN; IMMUNOGLOBULIN G;

ANTIBODY DETECTION; ANTIBODY PRODUCTION; ANTIBODY RESPONSE; ARTICLE; ASTROCYTOMA; BLOOD SAMPLING; BRAIN PSEUDOTUMOR; CENTRAL NERVOUS SYSTEM DISEASE; CEREBROSPINAL FLUID; CHILD; CHRONIC INFLAMMATION; CLINICAL ASSESSMENT; CONTROLLED STUDY; DNA EXTRACTION; EPILEPSY; EPSTEIN BARR VIRUS; FEMALE; HEADACHE; HERPES SIMPLEX VIRUS; HUMAN; HUMORAL IMMUNITY; IMMUNOPATHOLOGY; MAJOR CLINICAL STUDY; MALE; MEASLES; MIGRAINE; MULTIPLE SCLEROSIS; MYELOOPTIC NEUROPATHY; NEUROACANTHOCYTOSIS; NEUROTROPISM; ONSET AGE; OPTIC NEURITIS; PATHOGENESIS; PELIZAEUS MERZBACHER DISEASE; PRIORITY JOURNAL; PSYCHOSOMATIC DISORDER; RUBELLA; SEIZURE; VARICELLA ZOSTER VIRUS; VIRUS MENINGITIS;

ADOLESCENT; ADULT; AGE OF ONSET; AGED; ANTIBODIES, VIRAL; CENTRAL NERVOUS SYSTEM DISEASES; CHILD; COHORT STUDIES; FEMALE; HERPESVIRUS 3, HUMAN; HERPESVIRUS 4, HUMAN; HUMANS; LONGITUDINAL STUDIES; MALE; MIDDLE AGED; MORBILLIVIRUS; MULTIPLE SCLEROSIS; SIMPLEXVIRUS; YOUNG ADULT;

EID: 77949275878     PISSN: 03405354     EISSN: 14321459     Source Type: Journal    
DOI: 10.1007/s00415-009-5296-y     Document Type: Article

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