Recognizing uncertainty increases robustness and reproducibility of mass spectrometry-based protein inferences

Journal of Proteome Research

Volumn 11, Issue 12, 2012, Pages 5586-5591

  Serang, Oliver ^a   Moruz, Luminita ^b   Hoopmann, Michael R ^c   Käll, Lukas ^d  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b SCIENCE FOR LIFE LABORATORY   (Sweden)

^c INSTITUTE FOR SYSTEMS BIOLOGY   (United States)

^d ROYAL INSTITUTE OF TECHNOLOGY   (Sweden)

Author keywords

Human Du145 prostate cancer cell lines; parsimony; probabilistic protein inference; protein grouping

Indexed keywords

PROTEIN;

CANCER CELL CULTURE; CONTROLLED STUDY; HUMAN; HUMAN CELL; MALE; MASS SPECTROMETRY; PARSIMONY ANALYSIS; PRIORITY JOURNAL; PROBABILITY; PROSTATE CANCER; PROTEIN ANALYSIS; REPRODUCIBILITY; REVIEW; UNCERTAINTY;

CELL LINE, TUMOR; COMPUTATIONAL BIOLOGY; DATABASES, PROTEIN; HUMANS; MALE; MASS SPECTROMETRY; NEOPLASM PROTEINS; PEPTIDES; PROSTATIC NEOPLASMS; PROTEOMICS; REPRODUCIBILITY OF RESULTS; UNCERTAINTY;

EID: 84870878361     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr300426s     Document Type: Review

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