Structural mechanism of ubiquitin and NEDD8 deamidation catalyzed by bacterial effectors that induce macrophage-specific apoptosis

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 50, 2012, Pages 20395-20400

  Yao, Qing ^a,b   Cui, Jixin ^b   Wang, Jiayi ^c   Li, Ting ^b   Wan, Xiaobo ^b,c   Luo, Tianming ^b   Gong, Yi Nan ^b   Xu, Ying ^b   Huang, Niu ^b   Shao, Feng ^b  

^a CHINA AGRICULTURAL UNIVERSITY   (China)

^b NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES   (China)

^c GRADUATE SCHOOL OF PEKING UNION MEDICAL COLLEGE   (China)

Author keywords

Cullin neddylation; Enteropathogenic E. Coli; MLN4924; Transglutamination; Type III secretion system

Indexed keywords

NEDD8 PROTEIN; UBIQUITIN;

APOPTOSIS; ARTICLE; BURKHOLDERIA PSEUDOMALLEI; CATALYSIS; CONTROLLED STUDY; CRYSTAL STRUCTURE; DEAMINATION; DOWN REGULATION; ENZYME ACTIVATION; MACROPHAGE; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN STRUCTURE;

AMINO ACID SEQUENCE; ANIMALS; APOPTOSIS; BACTERIAL PROTEINS; BINDING SITES; BURKHOLDERIA PSEUDOMALLEI; CELL LINE; CRYSTALLOGRAPHY, X-RAY; HEK293 CELLS; HELA CELLS; HUMANS; MACROPHAGES; MICE; MODELS, MOLECULAR; MOLECULAR DYNAMICS SIMULATION; MOLECULAR SEQUENCE DATA; MULTIPROTEIN COMPLEXES; MUTAGENESIS, SITE-DIRECTED; SEQUENCE HOMOLOGY, AMINO ACID; STATIC ELECTRICITY; UBIQUITINS;

BACTERIA (MICROORGANISMS); BURKHOLDERIA PSEUDOMALLEI; EUKARYOTA;

EID: 84870875825     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1210831109     Document Type: Article

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