Circadian rhythm of melatonin and Alzheimer's disease

Progress in Biochemistry and Biophysics

Volumn 39, Issue 8, 2012, Pages 796-803

  Zhou, Jiang Ning ^a   Liu, Ya Jing ^a  

^a UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

Author keywords

Alzheimer's disease; Melatonin; Rhythm disturbance; Treatment

Indexed keywords

EID: 84870862877     PISSN: 10003282     EISSN: None     Source Type: Journal    
DOI: 10.3724/SP.J.1206.2012.00315     Document Type: Review

References (90)

1. Rosales-Corral S A, Acuna-Castroviejo D, Coto-Montes A, et al. Alzheimer's disease: Pathological mechanisms and the beneficial role of melatonin. J Pineal Res, 2012, 52( 2): 167-202
2. Tanzi R E. The synaptic Abeta hypothesis of Alzheimer disease. Nat Neurosa, 2005, 8( 8): 977-979
3. Yang X, Yang Y, Liu J, et al. Increased phosphorylation of tau and synaptic protein loss in the aged transgenic mice expressing familiar Alzheimer's disease-linked presenilin 1 mutation. Neurochem Res, 2012, 37( 1): 15-22
4. Marcello E, Epis R, Saraceno C, et al. Synaptic dysfunction in Alzheimer's disease. Adv Exp Med Biol, 2012, 970: 573-601
5. Ma T, Klann E. Amyloid beta: Linking synaptic plasticity failure to memory disruption in Alzheimer's disease. J Neurochem, 2012, 120( Suppl 1): 140-148
6. Zhou J N, Swaab D F. Age-related changes in neuropeptidergic neurons in the human hypothalamus//Macieira-Coelho A. Molecular Basis of Aging. Florida: CRC Press, 1995: 527-552
7. Wu Y H, Swaab D F. Disturbance and strategies for reactivation of the circadian rhythm system in aging and Alzheimer's disease. Sleep Med, 2007, 8( 6): 623-636
8. Harper D G, Volicer L, Stopa E G, et al. Disturbance of endogenous circadian rhythm in aging and Alzheimer's disease. Am J Geriatr Psychiatry, 2005, 13( 5): 359-368
9. Yesavage J A, Noda A, Hernandez B, et al. Circadian clock gene polymorphisms and sleep-wake disturbance in Alzheimer's disease. Am J Geriatr Psychiatry, 2011, 19( 7): 635-643
10. Pevet P, Challet E. Melatonin: Both master clock output and internal time-giver in the circadian clocks network. J Physiol Paris, 2011, 105( 4- 6): 170-182
11. Hardeland R, Madrid J A, Tan D X, et al. Melatonin, the circadian multioscillator system and health: The need for detailed analyses of peripheral melatonin signaling. J Pineal Res, 2012, 52( 2): 139-166
12. Galano A, Tan D X, Reiter R J. Melatonin as a natural ally against oxidative stress: A physicochemical examination. J Pineal Res, 2011, 51( 1): 1-16
13. Wang J, Hao H, Yao L, et al. Melatonin suppresses migration and invasion via inhibition of oxidative stress pathway in glioma cells. J Pineal Res, 2012, doi: 10.111l/j.l600-079X.2012.00985.x
14. Mares J, Pometlova M, Deykun K, et al. An isolated epileptic scizure elicits learning impairment which could be prevented by melatonin. Epilepsy Behav, 2012, 23( 3): 199-204
15. Saxena G, Bharti S, Kamat P K, et al. Melatonin alleviates memory deficits and neuronal degeneration induced by intracerebroventricular administration of streptozotocin in rats. Pharmacol Biochem Behav, 2010, 94( 3): 397-403
16. Wu C C, Lu K C, Lin G J, et al. Melatonin enhances endogenous heme oxygenase-1 and represses immune responses to ameliorate experimental murine membranous nephropathy. J Pineal Res, 2012, 52( 4): 460-469
17. Espino J, Bejarano I, Paredes S D, et al. Protective effect of melatonin against human leukocyte apoptosis induced by intracellular calcium overload: Relation with its antioxidant actions. J Pineal Res, 2011, 51( 2): 195-206
18. Foulkes N S, Borjigin J, Snyder S H, et al. Rhythmic transcription: The molecular basis of circadian melatonin synthesis. Trends Neurosci, 1997, 20( 10): 487-492
19. Wu Y H, Feenstra M G, Zhou J N, et al. Molecular changes underlying reduced pineal melatonin levels in Alzheimer's disease: Alterations in preclinical and clinical stages. J Clin Endocrinol Metab, 2003, 88( 12): 5898-5906
20. Liu T, Borjigin J. N-acetyltransferase is not the rate-limiting enzyme of melatonin synthesis at night. J Pineal Res, 2005, 39( 1): 91-96
21. Srinivasan V, Maestroni G J, Cardinali D P, et al. Melatonin, immune function and aging. Immun Ageing, 2005, 2( 1): 17
22. Hirata F, Hayaishi O, Tokuyama T, et al. In vitro and in vivo formation of two new metabolites of melatonin. J Biol Chem, 1974, 249( 4): 1311-1313
23. Gern W A, Ralph C L. Melatonin synthesis by the retina. Science, 1979, 204( 4389): 183-184
24. Itoh M T, Ishizuka B, Kuribayashi Y, et al. Melatonin, its precursors, and synthesizing enzyme activities in the human ovary. MoI Hum Reprod, 1999, 5( 5): 402-408
25. Itoh M T, Ishizuka B, Kudo Y, et al. Detection of melatonin and serotonin N-acetyltransferase and hydroxyindole-O-methyltransferase activities in rat ovary. Mol Cell Endocrinol, 1997, 136( 1): 7-13
26. Tijmes M, Pedraza R, Valladares L. Melatonin in the rat testis: Evidence for local synthesis. Steroids, 1996, 61( 2): 65-68
27. Djeridane Y, Vivien-Roels B, Simonneaux V, et al. Evidence for melatonin synthesis in rodent harderian gland: A dynamic in vitro study. J Pineal Res, 1998, 25( 1): 54-64
28. Bubenik G A. Localization, physiological significance and possible clinical implication of gastrointestinal melatonin. Biol Signals Recept, 2001, 10( 6): 350-366
29. Slominski A, Pisarchik A, Semak I, et al. Serotoninergic and melatoninergic systems are fully expressed in human skin. Faseb J, 2002, 16( 8): 896-898
30. Conti A, Conconi S, Hertens E, et al. Evidence for melatonin synthesis in mouse and human bone marrow cells. J Pineal Res, 2000, 28( 4): 193-202
31. Tan D X, Manchester L C, Reiter R J, et al. Identification of highly elevated levels of melatonin in bone marrow: Its origin and significance. Biochim Biophys Acta, 1999, 1472( 1- 2): 206-214
32. Carrillo-Vico A, Lardone P J, Fernandez-Santos J M, et al. Human lymphocyte-synthesized melatonin is involved in the regulation of the interleukin-2/interleukin-2 receptor system. J Clin Endocrinol Metab, 2005, 90( 2): 992-1000
33. Morera A L, Abreu P. Existence of melatonin in human platelets. J Pineal Res, 2005, 39( 4): 432-433
34. Tan D, Manchester L C, Reiter R J, et al. High physiological levels of melatonin in the bile of mammals. Life Sci, 1999, 65 ( 23): 2523-2529
35. Reppert S M, Godson C, Mahle C D, et al. Molecular characterization of a second melatonin receptor expressed in human retina and brain: The Mellb melatonin receptor. Proc Natl Acad Sci USA, 1995, 92( 19): 8734-8738
36. Fujieda H, Hamadanizadeh S A, Wankiewicz E, et al. Expression of mtl melatonin receptor in rat retina: Evidence for multiple cell targets for melatonin. Neuroscience, 1999, 93( 2): 793-799
37. Witt-Enderby P A, Masana M I, Dubocovich M L. Physiological exposure to melatonin supersensitizes the cyclic adenosine 3′, 5′-monophosphate- dependent signal transduction cascade in Chinese hamster ovary cells expressing the human mtl melatonin receptor. Endocrinology, 1998, 139( 7): 3064-3071
38. Pozo D, Delgado M, Fernandez-Santos J M, et al. Expression of the mella-melatonin receptor mRNA in T and B subsets of lymphocytes from rat thymus and spleen. Faseb J, 1997, 11( 6): 466-473
39. 3H]-melatonin in human platelets. J Pineal Res, 1992, 13( 2): 60-65
40. Adachi A, Natesan A K, Whitfield-Rucker M G, et al. Functional melatonin receptors and metabolic coupling in cultured chick astrocytes. Glia, 2002, 39( 3): 268-278
41. Tan D X, Manchester L C, Hardeland R, et al. Melatonin: A hormone, a tissue factor, an autocoid, a paracoid, and an antioxidant vitamin. J Pineal Res, 2003, 34( 1): 75-78
42. Liu Y J, Zhuang J, Zhu H Y, et al. Cultured rat cortical astrocytes synthesize melatonin: Absence of a diurnal rhythm. J Pineal Res, 2007, 43( 3): 232-238
43. Liu Y J, Meng F T, Wang L L, et al. Apolipoprotein E influences melatonin biosynthesis by regulating NAT and MAOA expression in C6 cells. J Pineal Res, 2012, 52( 4): 397-402
44. Jimenez-Jorge S, Guerrero J M, Jimenez-Caliani A J, et al. Evidence for melatonin synthesis in the rat brain during development. J Pineal Res, 2007, 42( 3): 240-246
45. Skinner D C, Malpaux B. High melatonin concentrations in third ventricular cerebrospinal fluid are not due to Galen vein blood recirculating through the choroid plexus. Endocrinology, 1999, 140( 10): 4399-4405
46. Stefulj J, Hortner M, Ghosh M, et al. Gene expression of the key enzymes of melatonin synthesis in extrapineal tissues of the rat. J Pineal Res, 2001, 30( 4): 243-247
47. Maldonado M D, Murillo-Cabezas F, Terron M P, et al. The potential of melatonin in reducing morbidity-mortality after craniocerebral trauma. J Pineal Res, 2007, 42( 1): 1-11
48. McIntyre I M, Norman T R, Burrows G D, et al. Melatonin rhythm in human plasma and saliva. J Pineal Res, 1987, 4( 2): 177-183
49. Vanecek J. Cellular mechanisms of melatonin action. Physiological Reviews, 1998, 78( 3): 687-721
50. Moller M, Ravault J P, Cozzi B, et al. The multineuronal input to the mammalian pineal gland. Adv Pineal Res, 1991, 6: 3-12
51. Zhou J N, Liu R Y, van Heerikhuize J, et al. Alterations in the circadian rhythm of salivary melatonin begin during middle-age. J Pineal Res, 2003, 34( 1): 11-16
52. Dubocovich M L. Melatonin receptors in the central nervous system. Adv Exp Med Biol, 1991, 294: 255-265
53. Wu Y H, Zhou J N, Van Heerikhuize J, et al. Decreased MT1 melatonin receptor expression in the suprachiasmatic nucleus in aging and Alzheimer's disease. Neurobiol Aging, 2007, 28 ( 8): 1239-1247
54. Wehr T A. The durations of human melatonin secretion and sleep respond to changes in daylength (photoperiod). J Clinical Endocrinology and Metabolism, 1991, 73( 6): 1276-1280
55. Reiter R J. The aging pineal-gland and its physiological consequences. Bioessays, 1992, 14( 3): 169-175
56. Ohashi Y, Okamoto N, Uchida K, et al. Daily rhythm of serum melatonin levels and effect of light exposure in patients with dementia of the Alzheimer's type. Biological Psychiatry, 1999, 45( 12): 1646-1652
57. Liu R Y, Zhou J N, van Heerikhuize J, et al. Decreased melatonin levels in postmortem cerebrospinal fluid in relation to aging, Alzheimer's disease, and apolipoprotein E-epsilon4/4 genotype. J Clin Endocrinol Metab, 1999, 84( 1): 323-327
58. Braak H, Braak E. Evolution of the neuropathology of Alzheimer's disease. Acta Neurologica Scandinavica, 1996, 165( suppl): 3-12
59. Hoppe J B, Frozza R L, Horn A P, et al. Amyloid-beta neurotoxicity in organotypic culture is attenuated by melatonin: Involvement of GSK.-3beta, tau and neuroinflammation. J Pineal Res, 2010, 48( 3): 230-238
60. Dragicevic N, Copes N, O'Neal-Moffitt G, et al. Melatonin treatment restores mitochondrial function in Alzheimer's mice: A mitochondrial protective role of melatonin membrane receptor signaling. J Pineal Res, 2011, 51( 1): 75-86
61. Singhal N K, Srivastava G, Agrawal S, et al. Melatonin as a neuroprotective agent in the rodent models of Parkinson's disease: Is it all set to irrefutable clinical translation?. Mol Neurobiol, 2012, 45( 1): 186-199
62. Pappolla M A, Chyan Y J, Poeggeler B, et al. An assessment of the antioxidant and the antiamyloidogenic properties of melatonin: Implications for Alzheimer's disease. J Neural Transm, 2000, 107( 2): 203-231
63. Matsubara E, Bryant-Thomas T, Pacheco Quinto J, et al. Melatonin increases survival and inhibits oxidative and amyloid pathology in a transgenic model of Alzheimer's disease. J Neurochem, 2003, 85( 5): 1101-1108
64. Strittmatter W J, Saunders A M, Schmechel D, et al. Apolipoprotein-E- high-avidity binding to beta-amyloid and increased frequency of type-4 allele in late-onset familial Alzheimer-disease. Proc Natl Aacd Sci USA, 1993, 90( 5): 1977-1981
65. Poeggeler B, Miravalle L, Zagorski M G, et al. Melatonin reverses the profibrillogenic activity of apolipoprotein E4 on the Alzheimer amyloid abeta peptide. Biochemistry, 2001, 40( 49): 14995-15001
66. Bondy S C, Sharman E H. Melatonin and the aging brain. Neurochem Int, 2007, 50( 4): 571-580b
67. Geoffriau M, Brun J, Chazot G, et al. The physiology and pharmacology of melatonin in humans. Horm Res, 1998, 49( 3- 4): 136-141
68. Sack R L, Lewy A J, Hughes R J. Use of melatonin for sleep and circadian rhythm disorders. Annals of Medicine, 1998, 30( 1): 115-121
69. Pétrie K, Dawson A G, Thompson L, et al. A double-blind trial of melatonin as a treatment for jet-lag in international cabin crew. Biological Psychiatry, 1993, 33( 7): 526-530
70. Sack R L, Lewy A J, Blood M L, et al. Melatonin administration to blind people-phase advances and entrainment. J Biological Rhythms, 1991, 6( 3): 249-261
71. Skene D J, Lockley S W, Arendt J. Melatonin in circadian sleep disorders in the blind. Biological Signals and Receptors, 1999, 8( 1- 2): 90-95
72. Peck J S, LeGoff D B, Ahmed I, et al. Cognitive effects of exogenous melatonin administration in elderly persons: A pilot study. Am J Geriatr Psychiatry, 2004, 12( 4): 432-436
73. Brusco L I, Marquez M, Cardinali D P. Melatonin treatment stabilizes chronobiologic and cognitive symptoms in Alzheimer's disease. Neuro Endocrinol Lett, 2000, 21( 1): 39-42
74. Zhou J W. Recent progress in neurodegenerative disorder research in China. Sci China Life Sci, 2010, 53( 3): 348-355
75. Cong L, Jia J. Promoter polymorphisms which regulate ADAM9 transcription are protective against sporadic Alzheimer's disease. Neurobiol Aging, 2011, 32( 1): 54-62
76. Tong Z Q, Han C S, Luo W H, et al. Accumulated hippocampal formaldehyde induces age-dependent memory decline. AGE, 2012, DOI: 10.1007/s11357-012-9388-8
77. He R Q, Lu J, Miao J Y. Formaldehyde stress. Sci China Life Sci, 2010, 53( 12): 1399-1404
78. Tong Z Q, Zhang J L, Luo W H, et al. Urine formaldehyde level is inversely correlated to mini mental state examination scores in senile dementia. Neurobiology of Aging, 2011, 32( 1): 31-41
79. Liu Y Y, Qiang M, Wei Y, et al. A novel molecular mechanism for nitrated α-synuclein-induced cell death. J Molecular Cell Biology, 2011, 3( 4): 239-249
80. Lu J, Miao J Y, Pan R, et al. Prog Biochem Biophys, 2011, 38( 12): 1113-1120
81. Sajjad Haider Naqvi, Wang W S, Miao J Y, et al. Prog Biochem Biophys, 2010, 37( 11): 1195-1203
82. Xu YX, Wand HQ, Zhao H, et al, Prog Biochem Biophys, 2011, 38( 10): 908-918
83. Zhang X H, Poo M M. Progress in neural plasticity. Sci China Life Sci, 2010, 53( 3): 322-329
84. Luo Z G. Synapse formation and remodeling. Axon guidance and neuronal migration research in China. Sci China Life Sci, 2010, 53( 3): 315-321
85. Zhang M, Zhao Z M, He L, et al. A meta-analysis of oxidative stress markers in schizophrenia. Sci China Life Sci, 2010, 53( 1): 112-124
86. Sun P, Zhang Q, Han J Y, et al. TLR4 signaling induced TLR2 expression in the process of mimic cerebral ischemia/reperfusion in vitro. Sci China Life Sci, 2010, 53( 2): 223-228
87. Wang Y Z, Xu T L. Ion channels in neuronal survival. Sci China Life Sci, 2010, 53( 3): 342-347
88. Luo Y F, Zhang J, Liu N Q, et al. Copper ions influence the toxicity of β-amyloid (1-42) in a concentration-dependent manner in a caenorhabditis elegans model of Alzheimer's disease. Sci China Life Sci, 2011, 54( 6): 527-534
89. Xu S J, Liu G L. Prog Biochem Biophys, 2010, 37( 6): 589-593
90. Riemersma-van der Lek R F, Swaab D F, Twisk J, et al. Effect of bright light and melatonin on cognitive and noncognitive function in elderly residents of group care facilities: A randomized controlled trial. Jama, 2008, 299( 22): 2642-2655