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Volumn 3, Issue , 2012, Pages

A peptide derived from laminin-γ3 reversibly impairs spermatogenesis in rats

Author keywords

[No Author keywords available]

Indexed keywords

FOCAL ADHESION KINASE; LAMININ; LAMININ GAMMA3; TYROSINE; UNCLASSIFIED DRUG;

EID: 84870783229     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms2171     Document Type: Article
Times cited : (60)

References (50)
  • 1
    • 0000585726 scopus 로고
    • The cytology of the testis
    • eds Knobil, E.*et al. Raven Press, New York
    • de Kretser, D.M. & Kerr, J.B. The cytology of the testis. in: The Physiology of Reproduction. Vol 1 (eds Knobil, E. et al.) 837-932 (Raven Press, New York, 1988).
    • (1988) The Physiology of Reproduction. , vol.1 , pp. 837-932
    • De Kretser, D.M.1    Kerr, J.B.2
  • 2
    • 83455163789 scopus 로고    scopus 로고
    • The blood-testis barrier and its implication in male contraception
    • Cheng, C.Y. & Mruk, D.D. The blood-testis barrier and its implication in male contraception. Pharmacol. Rev. 64, 16-64 (2012).
    • (2012) Pharmacol. Rev. , vol.64 , pp. 16-64
    • Cheng, C.Y.1    Mruk, D.D.2
  • 3
    • 0000212362 scopus 로고
    • Regulation of spermatogenesis
    • eds Knobil, E. & Neill, J.D.) Raven Press, New York
    • Sharpe, R.M. Regulation of spermatogenesis. in: The Physiology of Reproduction. (eds Knobil, E. & Neill, J.D.) 1363-1434 (Raven Press, New York, 1994).
    • (1994) The Physiology of Reproduction , pp. 1363-1434
    • Sharpe, R.M.1
  • 4
    • 0020181783 scopus 로고
    • Regulation of the seminiferous epithelium
    • Parvinen, M. Regulation of the seminiferous epithelium. Endocr. Rev. 3, 404-417 (1982).
    • (1982) Endocr. Rev. , vol.3 , pp. 404-417
    • Parvinen, M.1
  • 5
    • 73949148801 scopus 로고    scopus 로고
    • Spermatogenesis and cycle of the seminiferous epithelium
    • Hess, R.A. & de Franca, L.R. Spermatogenesis and cycle of the seminiferous epithelium. Adv. Exp. Med. Biol. 636, 1-15 (2008).
    • (2008) Adv. Exp. Med. Biol. , vol.636 , pp. 1-15
    • Hess, R.A.1    De Franca, L.R.2
  • 8
    • 46949109724 scopus 로고    scopus 로고
    • Anchoring junctions as drug targets: Role in contraceptive development
    • Mruk, D.D., Silvestrini, B. & Cheng, C.Y. Anchoring junctions as drug targets: role in contraceptive development. Pharmacol. Rev. 60, 146-180 (2008).
    • (2008) Pharmacol. Rev. , vol.60 , pp. 146-180
    • Mruk, D.D.1    Silvestrini, B.2    Cheng, C.Y.3
  • 9
    • 0036788073 scopus 로고    scopus 로고
    • Cell junction dynamics in the testis: Sertoli-germ cell interactions and male contraceptive development
    • Cheng, C.Y. & Mruk, D.D. Cell junction dynamics in the testis: Sertoli-germ cell interactions and male contraceptive development. Physiol. Rev. 82, 825-874 (2002).
    • (2002) Physiol. Rev. , vol.82 , pp. 825-874
    • Cheng, C.Y.1    Mruk, D.D.2
  • 10
    • 33745214011 scopus 로고    scopus 로고
    • Laminin a3 forms a complex with b3 and g3 chains that serves as the ligand for a6b1-integrin at the apical ectoplasmic specialization in adult rat testes
    • Yan, H.H.N. & Cheng, C.Y. Laminin a3 forms a complex with b3 and g3 chains that serves as the ligand for a6b1-integrin at the apical ectoplasmic specialization in adult rat testes. J. Biol. Chem. 281, 17286-17303 (2006).
    • (2006) J. Biol. Chem. , vol.281 , pp. 17286-17303
    • Yan, H.H.N.1    Cheng, C.Y.2
  • 11
    • 0028984244 scopus 로고
    • Integrin receptor a6b1 is localized at specific sites of cell-to-cell contact in rat seminiferous epithelium
    • Salanova, M., Stefanini, M., De Curtis, I. & Palombi, F. Integrin receptor a6b1 is localized at specific sites of cell-to-cell contact in rat seminiferous epithelium. Biol. Reprod. 52, 79-87 (1995).
    • (1995) Biol. Reprod. , vol.52 , pp. 79-87
    • Salanova, M.1    Stefanini, M.2    De Curtis, I.3    Palombi, F.4
  • 12
    • 77954024451 scopus 로고    scopus 로고
    • A local autocrine axis in the testes that regulates spermatogenesis
    • Cheng, C.Y. & Mruk, D.D. A local autocrine axis in the testes that regulates spermatogenesis. Nat. Rev. Endocrinol. 6, 380-395 (2010).
    • (2010) Nat. Rev. Endocrinol. , vol.6 , pp. 380-395
    • Cheng, C.Y.1    Mruk, D.D.2
  • 13
    • 33846586935 scopus 로고    scopus 로고
    • Ectoplasmic specialization: A friend or a foe of spermatogenesis?
    • Yan, H.H.N., Mruk, D.D., Lee, W.M. & Cheng, C.Y. Ectoplasmic specialization: a friend or a foe of spermatogenesis? BioEssays 29, 36-48 (2007).
    • (2007) BioEssays , vol.29 , pp. 36-48
    • Yan, H.H.N.1    Mruk, D.D.2    Lee, W.M.3    Cheng, C.Y.4
  • 14
    • 1242281830 scopus 로고    scopus 로고
    • Interactions of proteases, protease inhibitors, and the b1 integrin/laminin g3 protein complex in the regulation of ectoplasmic specialization dynamics in the rat testis
    • Siu, M.K.Y. & Cheng, C.Y. Interactions of proteases, protease inhibitors, and the b1 integrin/laminin g3 protein complex in the regulation of ectoplasmic specialization dynamics in the rat testis. Biol. Reprod. 70, 945-964 (2004).
    • (2004) Biol. Reprod. , vol.70 , pp. 945-964
    • Siu, M.K.Y.1    Cheng, C.Y.2
  • 15
    • 47749101115 scopus 로고    scopus 로고
    • An autocrine axis in the testis that coordinates spermiation and blood-testis barrier restructuring during spermatogenesis
    • Yan, H.H.N., Mruk, D.D., Wong, E.W.P., Lee, W.M. & Cheng, C.Y. An autocrine axis in the testis that coordinates spermiation and blood-testis barrier restructuring during spermatogenesis. Proc. Natl Acad. Sci. USA 105, 8950-8955 (2008).
    • (2008) Proc. Natl Acad. Sci. USA , vol.105 , pp. 8950-8955
    • Yan, H.H.N.1    Mruk, D.D.2    Wong, E.W.P.3    Lee, W.M.4    Cheng, C.Y.5
  • 16
    • 0025971895 scopus 로고
    • Influence of basement membrane molecules on directional migration of human breast cell lines in vitro
    • Coopman, P.J. et al. Influence of basement membrane molecules on directional migration of human breast cell lines in vitro. J. Cell. Sci. 98, 395-401 (1991).
    • (1991) J. Cell. Sci. , vol.98 , pp. 395-401
    • Coopman, P.J.1
  • 17
    • 0028948496 scopus 로고
    • Gated migration: Neurons migrate on but not onto substrates containing S-laminin
    • Porter, B.E. & Sanes, J.R. Gated migration: neurons migrate on but not onto substrates containing S-laminin. Dev. Biol. 167, 609-616 (1995).
    • (1995) Dev. Biol. , vol.167 , pp. 609-616
    • Porter, B.E.1    Sanes, J.R.2
  • 18
    • 77952293046 scopus 로고    scopus 로고
    • The role of a recombinant fragment of laminin-332 in integrin a3b1-dependent cell binding, spreading and migration
    • Yamashita, H. et al. The role of a recombinant fragment of laminin-332 in integrin a3b1-dependent cell binding, spreading and migration. Biomaterials 31, 51105-121 (2010).
    • (2010) Biomaterials , vol.31 , pp. 51105-51121
    • Yamashita, H.1
  • 19
    • 84862567996 scopus 로고    scopus 로고
    • The heterotrimeric laminin coiled-coil domain exerts anti-adhesive effects and induces a pro-invasive phenotype
    • Santos-Valle, P. et al. The heterotrimeric laminin coiled-coil domain exerts anti-adhesive effects and induces a pro-invasive phenotype. PLoS One 7, e39097 (2012).
    • (2012) PLoS One , vol.7
    • Santos-Valle, P.1
  • 20
    • 84855412261 scopus 로고    scopus 로고
    • Dissecting the phthalate-induced Sertoli cell injury: The fragile balance of proteases and their inhibitors
    • Mazaud-Guittot, S. Dissecting the phthalate-induced Sertoli cell injury: the fragile balance of proteases and their inhibitors. Biol. Reprod. 85, 1091-1093 (2011).
    • (2011) Biol. Reprod. , vol.85 , pp. 1091-1093
    • Mazaud-Guittot, S.1
  • 21
    • 62149144754 scopus 로고    scopus 로고
    • TNFa-mediated disruption of spermatogenesis in response to Sertoli cell injury in rodents is partially regulated by MMP2
    • Yao, P.L., Lin, Y.C. & Richburg, J.H. TNFa-mediated disruption of spermatogenesis in response to Sertoli cell injury in rodents is partially regulated by MMP2. Biol. Reprod. 80, 581-589 (2009).
    • (2009) Biol. Reprod. , vol.80 , pp. 581-589
    • Yao, P.L.1    Lin, Y.C.2    Richburg, J.H.3
  • 22
    • 77953085869 scopus 로고    scopus 로고
    • Mono-(2-ethylhexyl) phthalate-induced disruption of junctional complexes in the seminiferous epithelium of the rodent testis is mediated by MMP2
    • Yao, P.L., Lin, Y.C. & Richburg, J.H. Mono-(2-ethylhexyl) phthalate-induced disruption of junctional complexes in the seminiferous epithelium of the rodent testis is mediated by MMP2. Biol. Reprod. 82, 516-527 (2010).
    • (2010) Biol. Reprod. , vol.82 , pp. 516-527
    • Yao, P.L.1    Lin, Y.C.2    Richburg, J.H.3
  • 23
    • 84864510712 scopus 로고    scopus 로고
    • 397 exhibit antagonistic effects on blood-testis barrier dynamics in the rat
    • 397 exhibit antagonistic effects on blood-testis barrier dynamics in the rat. Proc. Natl Acad. Sci. USA 109, 12562-12567 (2012).
    • (2012) Proc. Natl Acad. Sci. USA , vol.109 , pp. 12562-12567
    • Lie, P.P.Y.1
  • 24
    • 1242342879 scopus 로고    scopus 로고
    • Zyxin, axin, and Wiskott-Aldrich syndrome protein are adaptors that link the cadherin/catenin protein complex to the cytoskeleton at adherens junctions in the seminiferous epithelium of the rat testis
    • Lee, N.P.Y., Mruk, D.D., Conway, A.M. & Cheng, C.Y. Zyxin, axin, and Wiskott-Aldrich syndrome protein are adaptors that link the cadherin/catenin protein complex to the cytoskeleton at adherens junctions in the seminiferous epithelium of the rat testis. J. Androl. 25, 200-215 (2004).
    • (2004) J. Androl. , vol.25 , pp. 200-215
    • Lee, N.P.Y.1    Mruk, D.D.2    Conway, A.M.3    Cheng, C.Y.4
  • 25
    • 21644457437 scopus 로고    scopus 로고
    • Sertoli-germ cell anchoring junction dynamics in the testis are regulated by an interplay of lipid and protein kinases
    • Siu, M.K.Y., Wong, C.H., Lee, W.M. & Cheng, C.Y. Sertoli-germ cell anchoring junction dynamics in the testis are regulated by an interplay of lipid and protein kinases. J. Biol. Chem. 280, 25029-25047 (2005).
    • (2005) J. Biol. Chem. , vol.280 , pp. 25029-25047
    • Siu, M.K.Y.1    Wong, C.H.2    Lee, W.M.3    Cheng, C.Y.4
  • 26
    • 77953764845 scopus 로고    scopus 로고
    • Crosstalk between desmoglein-2/desmocollin-2/Src kinase and coxsackie and adenovirus receptor/ZO-1 protein complexes, regulates blood-testis barrier dynamics
    • Lie, P.P.Y., Cheng, C.Y. & Mruk, D.D. Crosstalk between desmoglein-2/desmocollin-2/Src kinase and coxsackie and adenovirus receptor/ZO-1 protein complexes, regulates blood-testis barrier dynamics. Int. J. Biochem. Cell. Biol. 42, 975-986 (2010).
    • (2010) Int. J. Biochem. Cell. Biol. , vol.42 , pp. 975-986
    • Lie, P.P.Y.1    Cheng, C.Y.2    Mruk, D.D.3
  • 27
    • 69249232433 scopus 로고    scopus 로고
    • Disruption of the blood-testis barrier integrity by bisphenol A in vitro: Is this a suitable model for studying blood-testis barrier dynamics?
    • Li, M.W.M., Mruk, D.D., Lee, W.M. & Cheng, C.Y. Disruption of the blood-testis barrier integrity by bisphenol A in vitro: is this a suitable model for studying blood-testis barrier dynamics? Int. J. Biochem. Cell. Biol. 41, 2302-2314 (2009).
    • (2009) Int. J. Biochem. Cell. Biol. , vol.41 , pp. 2302-2314
    • Li, M.W.M.1    Mruk, D.D.2    Lee, W.M.3    Cheng, C.Y.4
  • 28
    • 0026544420 scopus 로고
    • Effect of Cadmium Chloride on Transepithelial Electrical Resistance of Sertoli Cell Monolayers in Two-compartment Cultures-a New Model for Toxicological Investigations of the 'blood-testis' barrier in vitro
    • Janecki, A., Jakubowiak, A. & Steinberger, A. Effect of cadmium chloride on transepithelial electrical resistance of Sertoli cell monolayers in two-compartment cultures\-a new model for toxicological investigations of the 'blood-testis' barrier in vitro. Toxicol. Appl. Pharmacol. 112, 51-57 (1992).
    • (1992) Toxicol. Appl. Pharmacol. , vol.112 , pp. 51-57
    • Janecki, A.1    Jakubowiak, A.2    Steinberger, A.3
  • 29
    • 0029905296 scopus 로고    scopus 로고
    • Effect of chloroquine on the formation of tight junctions in cultured immature rat Sertoli cells
    • Okanlawon, A. & Dym, M. Effect of chloroquine on the formation of tight junctions in cultured immature rat Sertoli cells. J. Androl. 17, 249-255 (1996).
    • (1996) J. Androl. , vol.17 , pp. 249-255
    • Okanlawon, A.1    Dym, M.2
  • 30
  • 31
    • 0034755902 scopus 로고    scopus 로고
    • A 22-amino acid synthetic peptide corresponding to the second extracellular loop of rat occludin perturbs the blood-testis barrier and disrupts spermatogenesis reversibly in vivo
    • Chung, N.P.Y., Mruk, D.D., Mo, M.Y., Lee, W.M. & Cheng, C.Y. A 22-amino acid synthetic peptide corresponding to the second extracellular loop of rat occludin perturbs the blood-testis barrier and disrupts spermatogenesis reversibly in vivo. Biol. Reprod. 65, 1340-1351 (2001).
    • (2001) Biol. Reprod. , vol.65 , pp. 1340-1351
    • Chung, N.P.Y.1    Mruk, D.D.2    Mo, M.Y.3    Lee, W.M.4    Cheng, C.Y.5
  • 32
    • 1342283974 scopus 로고    scopus 로고
    • Regulation of blood-testis barrier dynamics: An in vivo study
    • Wong, C.H., Mruk, D.D., Lui, W.Y. & Cheng, C.Y. Regulation of blood-testis barrier dynamics: an in vivo study. J. Cell. Sci. 117, 783-798 (2004).
    • (2004) J. Cell. Sci. , vol.117 , pp. 783-798
    • Wong, C.H.1    Mruk, D.D.2    Lui, W.Y.3    Cheng, C.Y.4
  • 33
    • 0014791176 scopus 로고
    • Changes in the Permeability of the Testicular Capillaries and of the 'blood-testis barrier' after injection of cadmium chloride in the rat
    • Setchell, B.P. & Waites, G.M.H. Changes in the permeability of the testicular capillaries and of the 'blood-testis barrier' after injection of cadmium chloride in the rat. J. Endocrinol. 47, 81-86 (1970).
    • (1970) J. Endocrinol. , vol.47 , pp. 81-86
    • Setchell, B.P.1    Waites, G.M.H.2
  • 34
    • 0027183210 scopus 로고
    • Cadmium in vivo causes disruption of tight junction-associated microfilaments in rat Sertoli cells
    • Hew, K.W., Heath, G.L., Jiwa, A.H. & Welsh, M.J. Cadmium in vivo causes disruption of tight junction-associated microfilaments in rat Sertoli cells. Biol. Reprod. 49, 840-849 (1993).
    • (1993) Biol. Reprod. , vol.49 , pp. 840-849
    • Hew, K.W.1    Heath, G.L.2    Jiwa, A.H.3    Welsh, M.J.4
  • 35
    • 0033635344 scopus 로고    scopus 로고
    • Complex phenotype of mice lacking occludin, a component of tight junction strands
    • Saitou, M. et al. Complex phenotype of mice lacking occludin, a component of tight junction strands. Mol. Biol. Cell. 11, 4131-4142 (2000).
    • (2000) Mol. Biol. Cell. , vol.11 , pp. 4131-4142
    • Saitou, M.1
  • 36
    • 36549051744 scopus 로고    scopus 로고
    • Production of knockout mice by gene targeting in multipotent germline stem cells
    • Takehashi, M. et al. Production of knockout mice by gene targeting in multipotent germline stem cells. Dev. Biol. 312, 344-352 (2007).
    • (2007) Dev. Biol. , vol.312 , pp. 344-352
    • Takehashi, M.1
  • 37
    • 0037306844 scopus 로고    scopus 로고
    • Is the cadherin/catenin complex a functional unit of cell-cell-actin- based adherens junctions (AJ) in the rat testis?
    • Lee, N.P.Y., Mruk, D.D., Lee, W.M. & Cheng, C.Y. Is the cadherin/catenin complex a functional unit of cell-cell-actin-based adherens junctions (AJ) in the rat testis? Biol. Reprod. 68, 489-508 (2003).
    • (2003) Biol. Reprod. , vol.68 , pp. 489-508
    • Lee, N.P.Y.1    Mruk, D.D.2    Lee, W.M.3    Cheng, C.Y.4
  • 38
    • 4644328373 scopus 로고    scopus 로고
    • Dynamic cross-talk between cells and the extracellular matrix in the testis
    • Siu, M.K.Y. & Cheng, C.Y. Dynamic cross-talk between cells and the extracellular matrix in the testis. BioEssays 26, 978-992 (2004).
    • (2004) BioEssays , vol.26 , pp. 978-992
    • Siu, M.K.Y.1    Cheng, C.Y.2
  • 39
    • 20544447160 scopus 로고    scopus 로고
    • Endostatin modulates VEGF-mediated barrier dysfunction in the retinal microvascular endothelium
    • Brankin, B., Campbell, M., Canning, P., Gardiner, T.A. & Stitt, A.W. Endostatin modulates VEGF-mediated barrier dysfunction in the retinal microvascular endothelium. Exp. Eye Res. 81, 22-31 (2005).
    • (2005) Exp. Eye Res. , vol.81 , pp. 22-31
    • Brankin, B.1    Campbell, M.2    Canning, P.3    Gardiner, T.A.4    Stitt, A.W.5
  • 40
    • 33845749032 scopus 로고    scopus 로고
    • Involvement of MAPKs in endostatin-mediated regulation of blood-retinal barrier function
    • Campbell, M. et al. Involvement of MAPKs in endostatin-mediated regulation of blood-retinal barrier function. Curr. Eye. Res. 31, 1033-1045 (2006).
    • (2006) Curr. Eye. Res. , vol.31 , pp. 1033-1045
    • Campbell, M.1
  • 41
    • 45749136698 scopus 로고    scopus 로고
    • Plasmin induces degradation and dysfunction of laminin 332 (laminin 5) and impaired assembly of basement membrane at the dermal-epidermal junction
    • Ogura, Y., Matsunaga, Y., Nishiyama, T. & Amano, S. Plasmin induces degradation and dysfunction of laminin 332 (laminin 5) and impaired assembly of basement membrane at the dermal-epidermal junction. Br. J. Dermatol. 159, 49-60 (2008).
    • (2008) Br. J. Dermatol. , vol.159 , pp. 49-60
    • Ogura, Y.1    Matsunaga, Y.2    Nishiyama, T.3    Amano, S.4
  • 42
    • 48149090563 scopus 로고    scopus 로고
    • Lack of collagen XVIII accelerates cutaneous wound healing, while overexpression of its endostatin domain leads to delayed healing
    • Seppinen, L. et al. Lack of collagen XVIII accelerates cutaneous wound healing, while overexpression of its endostatin domain leads to delayed healing. Matrix Biol. 27, 535-546 (2008).
    • (2008) Matrix Biol. , vol.27 , pp. 535-546
    • Seppinen, L.1
  • 43
    • 17644419365 scopus 로고    scopus 로고
    • Evidence for a role of ADAM17 (TACE) in the regulation of platelet glycoprotein v
    • Rabie, T., Strehl, A., Ludwig, A. & Nieswandt, B. Evidence for a role of ADAM17 (TACE) in the regulation of platelet glycoprotein V. J. Biol. Chem. 280, 14462-14468 (2005).
    • (2005) J. Biol. Chem. , vol.280 , pp. 14462-14468
    • Rabie, T.1    Strehl, A.2    Ludwig, A.3    Nieswandt, B.4
  • 44
    • 82755194760 scopus 로고    scopus 로고
    • Protein transduction domain delivery of therapeutic macromolecules
    • van den Berg, A. & Dowdy, S.F. Protein transduction domain delivery of therapeutic macromolecules. Curr. Opin. Biotechnol. 22, 888-893 (2011).
    • (2011) Curr. Opin. Biotechnol. , vol.22 , pp. 888-893
    • Van Den Berg, A.1    Dowdy, S.F.2
  • 45
    • 84856895124 scopus 로고    scopus 로고
    • Excision of HIV-1 proviral DNA by recombinant cell permeable tre-recombinase
    • Mariyanna, L. et al. Excision of HIV-1 proviral DNA by recombinant cell permeable tre-recombinase. PLoS One 7, e31576 (2012).
    • (2012) PLoS One , vol.7
    • Mariyanna, L.1
  • 46
    • 33750735046 scopus 로고    scopus 로고
    • A male contraceptive targeting germ cell adhesion
    • Mruk, D.D., Wong, C.H., Silvestrini, B. & Cheng, C.Y. A male contraceptive targeting germ cell adhesion. Nat. Med. 12, 1323-1328 (2006).
    • (2006) Nat. Med. , vol.12 , pp. 1323-1328
    • Mruk, D.D.1    Wong, C.H.2    Silvestrini, B.3    Cheng, C.Y.4
  • 47
    • 77955667310 scopus 로고    scopus 로고
    • Molecular diagnostic and drug delivery agents based on aptamer-nanomaterial conjugates
    • Lee, J.H., Vigit, M.V., Mazumdar, D. & Lu, Y. Molecular diagnostic and drug delivery agents based on aptamer-nanomaterial conjugates. Adv. Drug Deliv. Rev. 62, 592-605 (2010).
    • (2010) Adv. Drug Deliv. Rev. , vol.62 , pp. 592-605
    • Lee, J.H.1    Vigit, M.V.2    Mazumdar, D.3    Lu, Y.4
  • 48
    • 84857598444 scopus 로고    scopus 로고
    • The interplay of catechol ligands with nanoparticulate iron oxides
    • Yuen, A.K., Hutton, G.A.M., Masters, A.F. & Maschmeyer, T. The interplay of catechol ligands with nanoparticulate iron oxides. Dalton Trans. 41, 2545-2559 (2012).
    • (2012) Dalton Trans. , vol.41 , pp. 2545-2559
    • Yuen, A.K.1    Hutton, G.A.M.2    Masters, A.F.3    Maschmeyer, T.4
  • 49
    • 83755207358 scopus 로고    scopus 로고
    • P-glycoprotein regulates blood-testis barrier dynamics via its effects on the occludin/zonula occludens 1 (ZO-1) protein complex mediated by focal adhesion kinase (FAK)
    • Su, L., Mruk, D.D., Lui, W.Y., Lee, W.M. & Cheng, C.Y. P-glycoprotein regulates blood-testis barrier dynamics via its effects on the occludin/zonula occludens 1 (ZO-1) protein complex mediated by focal adhesion kinase (FAK). Proc. Natl Acad. Sci. USA 108, 19623-19628 (2011).
    • (2011) Proc. Natl Acad. Sci. USA , vol.108 , pp. 19623-19628
    • Su, L.1    Mruk, D.D.2    Lui, W.Y.3    Lee, W.M.4    Cheng, C.Y.5
  • 50
    • 0023184586 scopus 로고
    • Intratesticular injection as a method to assess the potential toxicity of various agents to study mechanisms of normal spermatogenesis
    • Russell, L.D., Saxena, N.K. & Weber, J.E. Intratesticular injection as a method to assess the potential toxicity of various agents to study mechanisms of normal spermatogenesis. Gamete Res. 17, 43-56 (1987).
    • (1987) Gamete Res. , vol.17 , pp. 43-56
    • Russell, L.D.1    Saxena, N.K.2    Weber, J.E.3


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