Crosstalk between desmoglein-2/desmocollin-2/Src kinase and coxsackie and adenovirus receptor/ZO-1 protein complexes, regulates blood-testis barrier dynamics

International Journal of Biochemistry and Cell Biology

Volumn 42, Issue 6, 2010, Pages 975-986

  Lie, Pearl P Y ^a   Cheng, C Yan ^a   Mruk, Dolores D ^a  

^a POPULATION COUNCIL   (United States)

Author keywords

Blood testis barrier; Desmosome; Sertoli cell; Testis

Indexed keywords

CADHERIN; COXSACKIE VIRUS AND ADENOVIRUS RECEPTOR; DESMOCOLLIN 2; DESMOGLEIN 2; MESSENGER RNA; PLAKOGLOBIN; PROTEIN ZO1; REGULATOR PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BLOOD TESTIS BARRIER; CELL CULTURE; CELL JUNCTION; COMPLEX FORMATION; CONTROLLED STUDY; DESMOSOME; ELECTRON MICROSCOPY; GENE EXPRESSION REGULATION; GENE SILENCING; GERM CELL; IMMUNOPRECIPITATION; IN VITRO STUDY; MALE; NONHUMAN; PERMEABILITY BARRIER; PROTEIN LOCALIZATION; RAT; REGULATORY MECHANISM; SERTOLI CELL; TIGHT JUNCTION;

ANIMALS; BLOOD-TESTIS BARRIER; CAPILLARY PERMEABILITY; CELLS, CULTURED; DESMOCOLLINS; DESMOGLEIN 2; DESMOSOMES; MALE; MEMBRANE PROTEINS; MULTIPROTEIN COMPLEXES; PHOSPHOPROTEINS; PROTEIN TRANSPORT; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RNA, SMALL INTERFERING; SERTOLI CELLS; SRC-FAMILY KINASES; TIGHT JUNCTIONS;

ADENOVIRIDAE;

EID: 77953764845     PISSN: 13572725     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biocel.2010.02.010     Document Type: Article

References (39)

1. Boutros T., Chevet E., Metrakos P. Mitogen-activated protein (MAP) kinase/MAP kinase phosphatase regulation: roles in cell growth, death, and cancer. Pharmacol Rev 2008, 60:261-310.
2. Cheng C.Y., Mathur P.P., Grima J. Structural analysis of clusterin and its subunits in ram rete testis fluid. Biochemistry 1988, 27:4079-4088.
3. Cheng C.Y., Mruk D.D. Tight junction assembly. Cell biology protocols 2006, 296-299. John Wiley & Sons, Hoboken. R. Harris, J. Graham, D. Rickwood (Eds.).
4. Chung N.P.Y., Mruk D.D., Mo M.Y., Lee W.M., Cheng CY. A 22-amino acid synthetic peptide corresponding to the second extracellular loop of rat occludin perturbs the blood-testis barrier and disrupts spermatogenesis reversibly in vivo. Biol Reprod 2001, 65:1340-1351.
5. Chung N.P.Y., Cheng C.Y. Is cadmium chloride-induced inter-Sertoli tight junction permeability barrier disruption a suitable in vitro model to study the events of junction disassembly during spermatogenesis in the rat testis?. Endocrinology 2001, 142:1878-1888.
6. Cohen C.J., Shieh J.T.C., Pickles R.J., Okegawa T., Hsieh J., Bergelson J.M. The coxsackievirus and adenovirus receptor is a transmembrane component of the tight junction. Proc Natl Acad Sci USA 2001, 98:15191-15196.
7. de Kretser D.M., Kerr J.B. The cytology of the testis. The physiology of reproduction 1988, 837-932. Raven Press, New York. E. Knobil, J.B. Neill, L.L. Ewing, G.S. Greenwald, C.L. Markert, D.W. Pfaff (Eds.).
8. Dejana E., Orsenigo F., Lampugnani M.G. The role of adherens junctions and VE-cadherin in the control of vascular permeability. J Cell Sci 2008, 121:2115-2122.
9. Galbiati F., Razani B., Lisanti M.P. Emerging themes in lipid rafts and caveolae. Cell 2001, 106:403-411.
10. Galdieri M., Ziparo E., Palombi F., Russo M.A., Stefanini M. Pure Sertoli cell cultures: a new model for the study of somatic-germ cell interactions. J Androl 1981, 5:249-259.
11. Gilleron J., Fiorini C., Carette D., Avondet C., Falk M.M., Segretain D., et al. Molecular reorganization of Cx43, ZO-1 and Src complexes during the endocytosis of gap junction plaques in response to a non-genomic carcinogen. J Cell Sci 2008, 121:4069-4078.
12. Gow A., Southwood C.M., Li J.S., Pariali M., Riordan G.P., Brodie S.E., et al. CNS myelin and Sertoli cell tight junction strands are absent in Osp/claudin-11 null mice. Cell 1999, 99:649-659.
13. Green K.J., Simpson C.L. Desmosomes: new perspectives on a classic. J Invest Dermatol 2007, 127:2499-2515.
14. Holthofer B., Windoffer R., Troyanovsky S., Leube R.E. Structure and function of desmosomes. Int Rev Cytol 2007, 264:65-163.
15. Kale G., Naren A.P., Sheth P., Rao R.K. Tyrosine phosphorylation of occludin attenuates its interactions with ZO-1, ZO-2, and ZO-3. Biochem Biophys Res Commun 2003, 302:324-329.
16. Kerr J.B., Loveland K.L., O'Bryan M.K., de Kretser D.M. Cytology of the testis and intrinsic control mechanisms. Knobil and Neill's physiology of reproduction 2006, 827-947. Elsevier, New York. J.D. Neill (Ed.).
17. Kowalczyk A.P., Palka H.L., Luu H.H., Nilles L.A., Anderson J.E., Wheelock M.J., et al. Post-translational regulation of plakoglobin expression. Influence of the desmosomal cadherins on plakoglobin metabolic stability. J Biol Chem 1994, 269:31214-31228.
18. Mirza M., Petersen C., Nordqvist K., Sollerbrant K. Coxsackie and adenovirus receptor (CAR) is upregulated in migratory germ cells during passage of the blood-testis barrier. Endocrinology 2007, 148:5459-5469.
19. Mruk D.D., Cheng C.Y. Sertoli-Sertoli and Sertoli-germ cell interactions and their significance in germ cell movement in the seminiferous epithelium during spermatogenesis. Endocr Rev 2004, 25:747-806.
20. Mruk D.D., Silvestrini B., Cheng C.Y. Anchoring junctions as drug targets: role in contraceptive development. Pharmacol Rev 2008, 60:146-180.
21. Mruk D.D., Siu M.K.Y., Conway A.M., Lee N.P.Y., Lau A.S.N., Cheng C.Y. Role of tissue inhibitor of metalloproteases-1 in junction dynamics in the testis. J Androl 2003, 24:510-523.
22. Ozaki-Kuroda K., Nakanishi H., Ohta H., Tanaka H., Kurihara H., Mueller S., et al. Nectin couples cell-cell adhesion and the actin scaffold at heterotypic testicular junctions. Curr Biol 2002, 12:1145-1150.
23. Perez-Moreno M., Fuchs E. Catenins: keeping cells from getting their signals crossed. Dev Cell 2006, 11:601-612.
24. Runswick S.K., O'Hare M.J., Jones L., Streuli C.H., Garrod D.R. Desmosomal adhesion regulates epithelial morphogenesis and cell positioning. Nat Cell Biol 2001, 3:823-830.
25. Russell L.D. Desmosome-like junctions between Sertoli and germ cells in the rat testis. Am J Anat 1977, 148:301-312.
26. Russell L.D. Movement of spermatocytes from the basal to the adluminal compartment of the rat testis. Am J Anat 1977, 148:313-328.
27. Russell L.D. Morphological and functional evidence for Sertoli-germ cell relationships. The Sertoli cell 1993, Cache River Press, Clearwater, pp. 365-90. L.D. Russell, M.D. Griswold (Eds.).
28. Russell L.D., Peterson R.N. Sertoli cell junctions: morphological and functional correlates. Int J Cytol 1985, 94:177-211.
29. Russell L.D., Tallon-Doran M., Weber J.E., Wong V., Peterson R.N. Three-dimensional reconstruction of a rat stage V Sertoli cell. III. A study of specific cellular relationships. Am J Anat 1983, 167:181-192.
30. Vogl A.W., Vaid K.S., Guttman J.A. The Sertoli cell cytoskeleton. Molecular mechanisms in spermatogenesis 2008, 186-211. Austin, Landes Bioscience and Springer Science+Business Media. C.Y. Cheng (Ed.).
31. Wang C.Q., Cheng C.Y. A seamless trespass: germ cell migration across the seminiferous epithelium during spermatogenesis. J Cell Biol 2007, 178:549-556.
32. Wang C.Q.F., Mruk D.D., Lee W.M., Cheng C.Y. Coxsackie and adenovirus receptor (CAR) is a product of Sertoli and germ cells in rat testes which is localized at the Sertoli-Sertoli and Sertoli-germ cell interface. Exp Cell Res 2007, 313:1373-1392.
33. Weiske J., Schoneberg T., Schroder W., Hatzfeld M., Tauber R., Huber O. The fate of desmosomal proteins in apoptotic cells. J Biol Chem 2001, 276:41175-41181.
34. Witcher L.L., Collins R., Puttagunta S., Mechanic S.E., Munson M., Gumbiner B.M., et al. Desmosomal cadherin binding domains of plakoglobin. J Biol Chem 1996, 271:10904-10909.
35. Yan H.H., Cheng C.Y. Blood-testis barrier dynamics are regulated by an engagement/disengagement mechanism between tight and adherens junctions via peripheral adaptors. Proc Natl Acad Sci USA 2005, 102:11722-11727.
36. Yan H.H.N., Cheng C.Y. Laminin α3 forms a complex with β3 and γ3 chains that serves as the ligand for α6β1 integrin at the apical ectoplasmic specialization in adult rat testes. J Biol Chem 2006, 281:17286-17303.
37. Yan H.H.N., Mruk D.D., Lee W.M., Cheng C.Y. Blood-testis barrier dynamics are regulated by testosterone and cytokines via their differential effects on the kinetics of protein endocytosis and recycling in Sertoli cells. FASEB J 2008, 22:1945-1959.
38. Yazama F. Continual maintenance of the blood-testis barrier during spermatogenesis: the intermediate compartment theory revisited. J Reprod Dev 2008, 54:299-305.
39. Young J.S., Guttman J.A., Vaid K.S., Shahinian H., Vogl A.W. Cortactin (CTTN), N-WASP (WASL) and clathrin (CLTC) are present at podosome-like tubulobulbar complexes in the rat testis. Biol Reprod 2009, 80:153-161.