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Volumn 86, Issue 24, 2012, Pages 13598-13608

Severe acute respiratory syndrome coronavirus protein nsp1 is a novel eukaryotic translation inhibitor that represses multiple steps of translation initiation

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; MUTANT PROTEIN; NONSTRUCTURAL PROTEIN 1; VIRUS PROTEIN;

EID: 84870710131     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.01958-12     Document Type: Article
Times cited : (158)

References (39)
  • 1
    • 33947396044 scopus 로고    scopus 로고
    • Novel beta-barrel fold in the nuclear magnetic resonance structure of the replicase nonstructural protein 1 from the severe acute respiratory syndrome coronavirus
    • Almeida MS, Johnson MA, Herrmann T, Geralt M, Wuthrich K. 2007. Novel beta-barrel fold in the nuclear magnetic resonance structure of the replicase nonstructural protein 1 from the severe acute respiratory syndrome coronavirus. J. Virol. 81:3151-3161.
    • (2007) J.Virol. , vol.81 , pp. 3151-3161
    • Almeida, M.S.1    Johnson, M.A.2    Herrmann, T.3    Geralt, M.4    Wuthrich, K.5
  • 2
    • 39949085583 scopus 로고    scopus 로고
    • Stress granules: the Tao of RNA triage
    • Anderson P, Kedersha N. 2008. Stress granules: the Tao of RNA triage. Trends Biochem. Sci. 33:141-150.
    • (2008) Trends Biochem.Sci. , vol.33 , pp. 141-150
    • Anderson, P.1    Kedersha, N.2
  • 3
    • 33646353201 scopus 로고    scopus 로고
    • Functional characterization of IRESes by an inhibitor of the RNA helicase eIF4A
    • Bordeleau ME, et al. 2006. Functional characterization of IRESes by an inhibitor of the RNA helicase eIF4A. Nat. Chem. Biol. 2:213-220.
    • (2006) Nat.Chem.Biol. , vol.2 , pp. 213-220
    • Bordeleau, M.E.1
  • 4
    • 33845950751 scopus 로고    scopus 로고
    • Eukaryotic initiation factor 2∞-independent pathway of stress granule induction by the natural product pateamine A
    • Dang Y, et al. 2006. Eukaryotic initiation factor 2∞-independent pathway of stress granule induction by the natural product pateamine A. J. Biol. Chem. 281:32870 -32878.
    • (2006) J.Biol.Chem. , vol.281 , pp. 32870-32878
    • Dang, Y.1
  • 5
    • 0037413818 scopus 로고    scopus 로고
    • Conversion of 48S translation preinitiation complexes into 80S initiation complexes as revealed by toeprinting
    • Dmitriev SE, Pisarev AV, Rubtsova MP, Dunaevsky YE, Shatsky IN. 2003. Conversion of 48S translation preinitiation complexes into 80S initiation complexes as revealed by toeprinting. FEBS Lett. 533:99 -104.
    • (2003) FEBS Lett , vol.533 , pp. 99-104
    • Dmitriev, S.E.1    Pisarev, A.V.2    Rubtsova, M.P.3    Dunaevsky, Y.E.4    Shatsky, I.N.5
  • 6
    • 0038523806 scopus 로고    scopus 로고
    • Identification of a novel coronavirus in patients with severe acute respiratory syndrome
    • Drosten C, et al. 2003. Identification of a novel coronavirus in patients with severe acute respiratory syndrome. N. Engl. J. Med. 348:1967-1976.
    • (2003) N.Engl.J.Med. , vol.348 , pp. 1967-1976
    • Drosten, C.1
  • 7
    • 33845623845 scopus 로고    scopus 로고
    • Structural and mechanistic insights into hepatitis C viral translation initiation
    • Fraser CS, Doudna JA. 2007. Structural and mechanistic insights into hepatitis C viral translation initiation. Nat. Rev. Microbiol. 5:29 -38.
    • (2007) Nat.Rev.Microbiol. , vol.5 , pp. 29-38
    • Fraser, C.S.1    Doudna, J.A.2
  • 8
    • 64049105338 scopus 로고    scopus 로고
    • The pathway of hepatitis C virus mRNA recruitment to the human ribosome
    • Fraser CS, Hershey JW, Doudna JA. 2009. The pathway of hepatitis C virus mRNA recruitment to the human ribosome. Nat. Struct. Mol. Biol. 16:397- 404.
    • (2009) Nat.Struct.Mol.Biol. , vol.16 , pp. 397-404
    • Fraser, C.S.1    Hershey, J.W.2    Doudna, J.A.3
  • 9
    • 84866149031 scopus 로고    scopus 로고
    • A common strategy for host RNA degradation by divergent viruses
    • Gaglia MM, Covarrubias S, Wong W, Glaunsinger BA. 2012. A common strategy for host RNA degradation by divergent viruses. J. Virol. 86:9527-9530.
    • (2012) J.Virol. , vol.86 , pp. 9527-9530
    • Gaglia, M.M.1    Covarrubias, S.2    Wong, W.3    Glaunsinger, B.A.4
  • 11
    • 78650074159 scopus 로고    scopus 로고
    • Alphacoronavirus transmissible gastroenteritis virus nsp1 protein suppresses protein translation in mammalian cells and in cell-free HeLa cell extracts but not in rabbit reticulocyte lysate
    • Huang C, et al. 2011. Alphacoronavirus transmissible gastroenteritis virus nsp1 protein suppresses protein translation in mammalian cells and in cell-free HeLa cell extracts but not in rabbit reticulocyte lysate. J. Virol.85:638-643.
    • (2011) J.Virol. , vol.85 , pp. 638-643
    • Huang, C.1
  • 12
    • 84855288589 scopus 로고    scopus 로고
    • SARS coronavirus nsp1 protein induces templatedependent endonucleolytic cleavage of mRNAs: viral mRNAs are resistant to nsp1-induced RNA cleavage
    • doi:10.1371/journal.ppat.1002433
    • Huang C, et al. 2011. SARS coronavirus nsp1 protein induces templatedependent endonucleolytic cleavage of mRNAs: viral mRNAs are resistant to nsp1-induced RNA cleavage. PLoS Pathog. 7:e1002433. doi:10.1371/journal.ppat.1002433.
    • (2011) PLoS Pathog. , vol.7
    • Huang, C.1
  • 13
    • 0037073485 scopus 로고    scopus 로고
    • Factorless ribosome assembly on the internal ribosome entry site of cricket paralysis virus
    • Jan E, Sarnow P. 2002. Factorless ribosome assembly on the internal ribosome entry site of cricket paralysis virus. J. Mol. Biol. 324:889 -902.
    • (2002) J.Mol.Biol. , vol.324 , pp. 889-902
    • Jan, E.1    Sarnow, P.2
  • 14
    • 0025145263 scopus 로고
    • Initiation of encephalomyocarditis virus RNA translation: the authentic initiation site is not selected by a scanning mechanism
    • Kaminski A, Howell MT, Jackson RJ. 1990. Initiation of encephalomyocarditis virus RNA translation: the authentic initiation site is not selected by a scanning mechanism. EMBO J. 9:3753-3759.
    • (1990) EMBO J , vol.9 , pp. 3753-3759
    • Kaminski, A.1    Howell, M.T.2    Jackson, R.J.3
  • 15
    • 70350768988 scopus 로고    scopus 로고
    • A two-pronged strategy to suppress host protein synthesis by SARS coronavirus Nsp1 protein
    • Kamitani W, Huang C, Narayanan K, Lokugamage KG, Makino S. 2009. A two-pronged strategy to suppress host protein synthesis by SARS coronavirus Nsp1 protein. Nat. Struct. Mol. Biol. 16:1134 -1140.
    • (2009) Nat.Struct.Mol.Biol. , vol.16 , pp. 1134-1140
    • Kamitani, W.1    Huang, C.2    Narayanan, K.3    Lokugamage, K.G.4    Makino, S.5
  • 16
    • 33748046163 scopus 로고    scopus 로고
    • Severe acute respiratory syndrome coronavirus nsp1 protein suppresses host gene expression by promoting host mRNA degradation
    • Kamitani W, et al. 2006. Severe acute respiratory syndrome coronavirus nsp1 protein suppresses host gene expression by promoting host mRNA degradation. Proc. Natl. Acad. Sci. U. S. A. 103:12885-12890.
    • (2006) Proc.Natl.Acad.Sci.U.S.A. , vol.103 , pp. 12885-12890
    • Kamitani, W.1
  • 17
    • 0032212132 scopus 로고    scopus 로고
    • Primer extension analysis of eukaryotic ribosome-mRNA complexes
    • Kozak M. 1998. Primer extension analysis of eukaryotic ribosome-mRNA complexes. Nucleic Acids Res. 26:4853- 4859.
    • (1998) Nucleic Acids Res. , vol.26 , pp. 4853-4859
    • Kozak, M.1
  • 18
    • 0038076030 scopus 로고    scopus 로고
    • A novel coronavirus associated with severe acute respiratory syndrome
    • Ksiazek TG, et al. 2003. A novel coronavirus associated with severe acute respiratory syndrome. N. Engl. J. Med. 348:1953-1966.
    • (2003) N.Engl.J.Med. , vol.348 , pp. 1953-1966
    • Ksiazek, T.G.1
  • 19
    • 0042198682 scopus 로고    scopus 로고
    • Newly discovered coronavirus as the primary cause of severe acute respiratory syndrome
    • Kuiken T, et al. 2003. Newly discovered coronavirus as the primary cause of severe acute respiratory syndrome. Lancet 362:263-270.
    • (2003) Lancet , vol.362 , pp. 263-270
    • Kuiken, T.1
  • 20
    • 0038823524 scopus 로고    scopus 로고
    • The genome sequence of the SARS-associated coronavirus
    • Marra MA, et al. 2003. The genome sequence of the SARS-associated coronavirus. Science 300:1399 -1404.
    • (2003) Science , vol.300 , pp. 1399-1404
    • Marra, M.A.1
  • 21
    • 33749493493 scopus 로고    scopus 로고
    • Inhibition of ribosome recruitment induces stress granule formation independently of eukaryotic initiation factor 2∞ phosphorylation
    • Mazroui R, et al. 2006. Inhibition of ribosome recruitment induces stress granule formation independently of eukaryotic initiation factor 2∞ phosphorylation. Mol. Biol. Cell 17:4212- 4219.
    • (2006) Mol.Biol.Cell , vol.17 , pp. 4212-4219
    • Mazroui, R.1
  • 22
    • 42449102158 scopus 로고    scopus 로고
    • Severe acute respiratory syndrome coronavirus nsp1 suppresses host gene expression, including that of type I interferon,in infected cells
    • Narayanan K, et al. 2008. Severe acute respiratory syndrome coronavirus nsp1 suppresses host gene expression, including that of type I interferon,in infected cells. J. Virol. 82:4471- 4479.
    • (2008) J.Virol. , vol.82 , pp. 4471-4479
    • Narayanan, K.1
  • 23
    • 2342614116 scopus 로고    scopus 로고
    • Inhibitors of protein synthesis identified by a high throughput multiplexed translation screen
    • Novac O, Guenier AS, Pelletier J. 2004. Inhibitors of protein synthesis identified by a high throughput multiplexed translation screen. Nucleic Acids Res. 32:902-915.
    • (2004) Nucleic Acids Res , vol.32 , pp. 902-915
    • Novac, O.1    Guenier, A.S.2    Pelletier, J.3
  • 24
    • 0035951373 scopus 로고    scopus 로고
    • Lipoxygenase mRNA silencing in erythroid differentiation: the 3=UTR regulatory complex controls 60S ribosomal subunit joining
    • Ostareck DH, Ostareck-Lederer A, Shatsky IN, Hentze MW. 2001. Lipoxygenase mRNA silencing in erythroid differentiation: the 3=UTR regulatory complex controls 60S ribosomal subunit joining. Cell 104:281-290.
    • (2001) Cell , vol.104 , pp. 281-290
    • Ostareck, D.H.1    Ostareck-lederer, A.2    Shatsky, I.N.3    Hentze, M.W.4
  • 25
    • 33847417585 scopus 로고    scopus 로고
    • P bodies and the control of mRNA translation and degradation
    • Parker R, Sheth U. 2007. P bodies and the control of mRNA translation and degradation. Mol. Cell 25:635- 646.
    • (2007) Mol.Cell , vol.25 , pp. 635-646
    • Parker, R.1    Sheth, U.2
  • 26
    • 0242717589 scopus 로고    scopus 로고
    • Coronavirus as a possible cause of severe acute respiratory syndrome
    • Peiris JS, et al. 2003. Coronavirus as a possible cause of severe acute respiratory syndrome. Lancet 361:1319 -1325.
    • (2003) Lancet , vol.361 , pp. 1319-1325
    • Peiris, J.S.1
  • 27
    • 0037439060 scopus 로고    scopus 로고
    • Translation elongation after assembly of ribosomes on the Cricket paralysis virus internal ribosomal entry site without initiation factors or initiator tRNA
    • Pestova TV, Hellen CU. 2003. Translation elongation after assembly of ribosomes on the Cricket paralysis virus internal ribosomal entry site without initiation factors or initiator tRNA. Genes Dev. 17:181-186.
    • (2003) Genes Dev. , vol.17 , pp. 181-186
    • Pestova, T.V.1    Hellen, C.U.2
  • 28
    • 0035912725 scopus 로고    scopus 로고
    • Molecular mechanisms of translation initiation in eukaryotes
    • Pestova TV, et al. 2001. Molecular mechanisms of translation initiation in eukaryotes. Proc. Natl. Acad. Sci. U. S. A. 98:7029 -7036.
    • (2001) Proc.Natl.Acad.Sci.U.S.A. , vol.98 , pp. 7029-7036
    • Pestova, T.V.1
  • 29
    • 38449123748 scopus 로고    scopus 로고
    • Assembly and analysis of eukaryotic translation initiation complexes
    • Pisarev AV, Unbehaun A, Hellen CU, Pestova TV. 2007. Assembly and analysis of eukaryotic translation initiation complexes. Methods Enzymol.430:147-177.
    • (2007) Methods Enzymol. , vol.430 , pp. 147-177
    • Pisarev, A.V.1    Unbehaun, A.2    Hellen, C.U.3    Pestova, T.V.4
  • 30
    • 0037561920 scopus 로고    scopus 로고
    • Characterization of a novel coronavirus associated with severe acute respiratory syndrome
    • Rota PA, et al. 2003. Characterization of a novel coronavirus associated with severe acute respiratory syndrome. Science 300:1394-1399.
    • (2003) Science , vol.300 , pp. 1394-1399
    • Rota, P.A.1
  • 31
    • 77249087063 scopus 로고    scopus 로고
    • Inhibition of eukaryotic translation elongation by cycloheximide and lactimidomycin
    • Schneider-Poetsch T, et al. 2010. Inhibition of eukaryotic translation elongation by cycloheximide and lactimidomycin. Nat. Chem. Biol. 6:209-217.
    • (2010) Nat. Chem. Biol. , vol.6 , pp. 209-217
    • Schneider-poetsch, T.1
  • 32
    • 60149091189 scopus 로고    scopus 로고
    • Regulation of translation initiation in eukaryotes: mechanisms and biological targets
    • Sonenberg N, Hinnebusch AG. 2009. Regulation of translation initiation in eukaryotes: mechanisms and biological targets. Cell 136:731-745.
    • (2009) Cell , vol.136 , pp. 731-745
    • Sonenberg, N.1    Hinnebusch, A.G.2
  • 33
    • 4644247805 scopus 로고    scopus 로고
    • Cryo-EM visualization of a viral internal ribosome entry site bound to human ribosomes: the IRES functions as an RNAbased translation factor
    • Spahn CM, et al. 2004. Cryo-EM visualization of a viral internal ribosome entry site bound to human ribosomes: the IRES functions as an RNAbased translation factor. Cell 118:465-475.
    • (2004) Cell , vol.118 , pp. 465-475
    • Spahn, C.M.1
  • 34
    • 0035831269 scopus 로고    scopus 로고
    • Hepatitis C virus IRES RNA-induced changes in the conformation of the 40s ribosomal subunit
    • Spahn CM, et al. 2001. Hepatitis C virus IRES RNA-induced changes in the conformation of the 40s ribosomal subunit. Science 291:1959-1962.
    • (2001) Science , vol.291 , pp. 1959-1962
    • Spahn, C.M.1
  • 35
    • 84869037184 scopus 로고    scopus 로고
    • Severe acute respiratory syndrome coronavirus nsp1 facilitates efficient propagation in cells through a specific translational shutoff of hostmRNA
    • Tanaka T, Kamitani W, Dediego ML, Enjuanes L, Matsuura Y. 2012. Severe acute respiratory syndrome coronavirus nsp1 facilitates efficient propagation in cells through a specific translational shutoff of hostmRNA. J. Virol. 86:11128-11137.
    • (2012) J. Virol. , vol.86 , pp. 11128-11137
    • Tanaka, T.1    Kamitani, W.2    Dediego, M.L.3    Enjuanes, L.4    Matsuura, Y.5
  • 36
    • 65349112441 scopus 로고    scopus 로고
    • Suppression of host gene expression by nsp1 proteins of group 2 bat coronaviruses
    • Tohya Y, et al. 2009. Suppression of host gene expression by nsp1 proteins of group 2 bat coronaviruses. J. Virol. 83:5282-5288.
    • (2009) J. Virol. , vol.83 , pp. 5282-5288
    • Tohya, Y.1
  • 37
    • 35448939321 scopus 로고    scopus 로고
    • Severe acute respiratory syndrome coronavirus evades antiviral signaling: role of nsp1 and rational design of an attenuated strain
    • Wathelet MG, Orr M, Frieman MB, Baric RS. 2007. Severe acute respiratory syndrome coronavirus evades antiviral signaling: role of nsp1 and rational design of an attenuated strain. J. Virol. 81:11620-11633.
    • (2007) J. Virol. , vol.81 , pp. 11620-11633
    • Wathelet, M.G.1    Orr, M.2    Frieman, M.B.3    Baric, R.S.4
  • 38
    • 0034682720 scopus 로고    scopus 로고
    • Initiation of protein synthesis from the A site of the ribosome
    • Wilson JE, Pestova TV, Hellen CU, Sarnow P. 2000. Initiation of protein synthesis from the A site of the ribosome. Cell 102:511-520.
    • (2000) Cell , vol.102 , pp. 511-520
    • Wilson, J.E.1    Pestova, T.V.2    Hellen, C.U.3    Sarnow, P.4
  • 39
    • 34548425017 scopus 로고    scopus 로고
    • Coronavirus non-structural protein 1 is a major pathogenicity factor: implications for the rational design of coronavirus vaccines
    • doi:10.1371/journal. ppat.0030109
    • Zust R, et al. 2007. Coronavirus non-structural protein 1 is a major pathogenicity factor: implications for the rational design of coronavirus vaccines. PLoS Pathog. 3:e109. doi:10.1371/journal. ppat.0030109
    • (2007) PLoS Pathog. , vol.3
    • Zust, R.1


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