Cryo-EM visualization of a viral internal ribosome entry site bound to human ribosomes: The IRES functions as an RNA-based translation factor

Cell

Volumn 118, Issue 4, 2004, Pages 465-475

  Spahn, Christian M T ^a,b,d   Jan, Eric ^e   Mulder, Anke ^a,b,f   Grassucci, Robert A ^a,b   Sarnow, Peter ^e   Frank, Joachim ^a,b,c  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b WADSWORTH CENTER   (United States)

^c STATE UNIVERSITY OF NEW YORK   (United States)

^d CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^e STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f PURDUE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN SUBUNIT; RNA; MESSENGER RNA; TRANSFER RNA; VIRUS RNA;

ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRICKET PARALYSIS VIRUS; DEVICE; GENE MAPPING; HUMAN; HUMAN CELL; INTERNAL RIBOSOME ENTRY SITE; NONHUMAN; PRIORITY JOURNAL; PROTEIN STRUCTURE; RIBOSOME; RNA TRANSLATION; VIRUS; CHEMICAL STRUCTURE; CHEMISTRY; CRYOELECTRON MICROSCOPY; ESCHERICHIA COLI; HELA CELL; METABOLISM; METHODOLOGY; NUCLEOTIDE SEQUENCE; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN SYNTHESIS;

CRICKET PARALYSIS VIRUS; EUKARYOTA; RNA VIRUSES;

CONSERVED SEQUENCE; CRYOELECTRON MICROSCOPY; ESCHERICHIA COLI; HELA CELLS; HUMANS; MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN BIOSYNTHESIS; PROTEIN CONFORMATION; RIBOSOMES; RNA, MESSENGER; RNA, TRANSFER; RNA, VIRAL;

EID: 4644247805     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cell.2004.08.001     Document Type: Article

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