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Volumn 45, Issue 1, 2013, Pages 23-29

Anthocyanins block ischemia-induced apoptosis in the perfused heart and support mitochondrial respiration potentially by reducing cytosolic cytochrome c

Author keywords

Cardioprotection; Caspases; Cytochrome c; Heart ischemia; Mitochondria

Indexed keywords

ANTHOCYANIN; CASPASE; CYANIDIN 3 GLUCOSIDE; CYTOCHROME C; DELPHINIDIN 3 GLUCOSIDE; MALVINIDIN 3 GLUCOSIDE; UNCLASSIFIED DRUG;

EID: 84870688186     PISSN: 13572725     EISSN: 18785875     Source Type: Journal    
DOI: 10.1016/j.biocel.2012.07.022     Document Type: Article
Times cited : (54)

References (38)
  • 1
    • 59249086196 scopus 로고    scopus 로고
    • Mechanisms of flavonoid protection against myocardial ischemia-reperfusion injury
    • M. Akhlaghi, and B. Bandy Mechanisms of flavonoid protection against myocardial ischemia-reperfusion injury Journal of Molecular and Cellular Cardiology 46 2009 309 317
    • (2009) Journal of Molecular and Cellular Cardiology , vol.46 , pp. 309-317
    • Akhlaghi, M.1    Bandy, B.2
  • 2
    • 0037400114 scopus 로고    scopus 로고
    • Cyanidin-3-O-β-glucopyranoside protects myocardium and erythrocytes from oxygen radical-mediated damages
    • A.M. Amorini, G. Lazzarino, F. Galvano, G. Fazzina, B. Tavazzi, and G. Galvano Cyanidin-3-O-β-glucopyranoside protects myocardium and erythrocytes from oxygen radical-mediated damages Free Radical Research 37 2003 453 460
    • (2003) Free Radical Research , vol.37 , pp. 453-460
    • Amorini, A.M.1    Lazzarino, G.2    Galvano, F.3    Fazzina, G.4    Tavazzi, B.5    Galvano, G.6
  • 3
    • 79551500592 scopus 로고    scopus 로고
    • Tetramethylphenylenediamine protects the isolated heart against ischaemia-induced apoptosis and reperfusion-induced necrosis
    • J. Barauskaite, R. Grybauskiene, R. Morkuniene, V. Borutaite, and C.G. Brown Tetramethylphenylenediamine protects the isolated heart against ischaemia-induced apoptosis and reperfusion-induced necrosis British Journal of Pharmacology 162 2011 1136 1142
    • (2011) British Journal of Pharmacology , vol.162 , pp. 1136-1142
    • Barauskaite, J.1    Grybauskiene, R.2    Morkuniene, R.3    Borutaite, V.4    Brown, C.G.5
  • 4
    • 0033520463 scopus 로고    scopus 로고
    • The mitochondrial apoptotic pathway is activated by serum and glucose deprivation in cardiac myocytes
    • S. Bialik, V.L. Cryns, A. Drincic, S. Miyata, A.L. Wollowick, and A. Srinivasan The mitochondrial apoptotic pathway is activated by serum and glucose deprivation in cardiac myocytes Circulation Research 85 1999 403 414
    • (1999) Circulation Research , vol.85 , pp. 403-414
    • Bialik, S.1    Cryns, V.L.2    Drincic, A.3    Miyata, S.4    Wollowick, A.L.5    Srinivasan, A.6
  • 5
    • 0030777615 scopus 로고    scopus 로고
    • The protective effect of late preconditioning against myocardial stunning in conscious rabbits is mediated by nitric oxide synthase. Evidence that nitric oxide acts both as a trigger and as a mediator of the late phase of ischemic preconditioning
    • R. Bolli, S. Manchikalapudi, X.L. Tang, H. Takano, Y. Qiu, and Y. Guo The protective effect of late preconditioning against myocardial stunning in conscious rabbits is mediated by nitric oxide synthase. Evidence that nitric oxide acts both as a trigger and as a mediator of the late phase of ischemic preconditioning Circulation Research 81 1997 1094 1107
    • (1997) Circulation Research , vol.81 , pp. 1094-1107
    • Bolli, R.1    Manchikalapudi, S.2    Tang, X.L.3    Takano, H.4    Qiu, Y.5    Guo, Y.6
  • 6
    • 35748954935 scopus 로고    scopus 로고
    • Mitochondrial regulation of caspase activation by cytochrome oxidase and tetramethylphenylenediamine via cytosolic cytochrome c redox state
    • V. Borutaite, and G.C. Brown Mitochondrial regulation of caspase activation by cytochrome oxidase and tetramethylphenylenediamine via cytosolic cytochrome c redox state Journal of Biological Chemistry 282 2007 31124 31130
    • (2007) Journal of Biological Chemistry , vol.282 , pp. 31124-31130
    • Borutaite, V.1    Brown, G.C.2
  • 8
    • 39549102405 scopus 로고    scopus 로고
    • Ischemic defects in the electron transport chain increase the production of reactive oxygen species from isolated rat heart mitochondria
    • Q. Chen, S. Moghaddas, C.L. Hoppel, and E.J. Lesnefsky Ischemic defects in the electron transport chain increase the production of reactive oxygen species from isolated rat heart mitochondria American Journal of Physiology. Cell Physiology 294 2008 C460 C466
    • (2008) American Journal of Physiology. Cell Physiology , vol.294
    • Chen, Q.1    Moghaddas, S.2    Hoppel, C.L.3    Lesnefsky, E.J.4
  • 13
    • 0035451525 scopus 로고    scopus 로고
    • Does the redox status of cytochrome c act as a fail-safe mechanism in the regulation of programmed cell death
    • J.T. Hancock, R. Desikan, and S.J. Neill Does the redox status of cytochrome c act as a fail-safe mechanism in the regulation of programmed cell death Free Radical Biology and Medicine 31 2001 697 703
    • (2001) Free Radical Biology and Medicine , vol.31 , pp. 697-703
    • Hancock, J.T.1    Desikan, R.2    Neill, S.J.3
  • 15
    • 81155128482 scopus 로고    scopus 로고
    • Complex i and cytochrome c are molecular targets of flavonoids that inhibit hydrogen peroxide production by mitochondria
    • R. Lagoa, I. Graziani, C. Lopez-Sanchez, V. Garcia-Martinez, and C. Gutierrez-Merino Complex I and cytochrome c are molecular targets of flavonoids that inhibit hydrogen peroxide production by mitochondria Biochimica et Biophysica Acta 1807 2011 1562 1572
    • (2011) Biochimica et Biophysica Acta , vol.1807 , pp. 1562-1572
    • Lagoa, R.1    Graziani, I.2    Lopez-Sanchez, C.3    Garcia-Martinez, V.4    Gutierrez-Merino, C.5
  • 16
    • 50949108782 scopus 로고    scopus 로고
    • Cardiolipin as an oxidative target in cardiac mitochondria in the aged rat
    • E.J. Lesnefsky, and C.L. Hoppel Cardiolipin as an oxidative target in cardiac mitochondria in the aged rat Biochimica et Biophysica Acta 1777 2008 1020 1027
    • (2008) Biochimica et Biophysica Acta , vol.1777 , pp. 1020-1027
    • Lesnefsky, E.J.1    Hoppel, C.L.2
  • 17
    • 0030715323 scopus 로고    scopus 로고
    • Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
    • P. Li, D. Nijhawan, I. Budihardjo, S.M. Srinivasula, M. Ahmad, and E.S. Alnemri Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade Cell 91 1997 479 499
    • (1997) Cell , vol.91 , pp. 479-499
    • Li, P.1    Nijhawan, D.2    Budihardjo, I.3    Srinivasula, S.M.4    Ahmad, M.5    Alnemri, E.S.6
  • 18
    • 77950816050 scopus 로고    scopus 로고
    • Purple sweet potato color alleviates d-galactose-induced brain aging in old mice by promoting survival of neurons via PI3K pathway and inhibiting cytochrome c-mediated apoptosis
    • J. Lu, D.M. Wu, Y.L.u.B. heng, and Z.F. hang Purple sweet potato color alleviates d-galactose-induced brain aging in old mice by promoting survival of neurons via PI3K pathway and inhibiting cytochrome c-mediated apoptosis Brain Pathology 20 2010 598 612
    • (2010) Brain Pathology , vol.20 , pp. 598-612
    • Lu, J.1    Wu, D.M.2    Heng, U.L.Y.B.3    Hang, Z.F.4
  • 19
    • 79960638507 scopus 로고    scopus 로고
    • Neuroprotective effect of cyaniding-3-O-glucoside anthocyanin in mice with focal cerebral ischemia
    • J. Min, S.W. Yu, S.H. Baek, K.M. Nair, O.N. Bae, and A. Bhatt Neuroprotective effect of cyaniding-3-O-glucoside anthocyanin in mice with focal cerebral ischemia Neuroscience Letters 500 2011 157 161
    • (2011) Neuroscience Letters , vol.500 , pp. 157-161
    • Min, J.1    Yu, S.W.2    Baek, S.H.3    Nair, K.M.4    Bae, O.N.5    Bhatt, A.6
  • 21
    • 0032793203 scopus 로고    scopus 로고
    • Analysis of redox regulation of cytochrome c-induced apoptosis in a cell-free system
    • Z. Pan, D.W. Voehringer, and R.E. Meyn Analysis of redox regulation of cytochrome c-induced apoptosis in a cell-free system Cell Death and Differentiation 6 1999 683 688
    • (1999) Cell Death and Differentiation , vol.6 , pp. 683-688
    • Pan, Z.1    Voehringer, D.W.2    Meyn, R.E.3
  • 22
    • 79956030668 scopus 로고    scopus 로고
    • The role of oxidized cytochrome c in regulating mitochondrial reactive oxygen species production and its perturbation in ischaemia
    • P. Pasdois, J.E. Parker, E.J. Griffiths, and A.P. Halestrap The role of oxidized cytochrome c in regulating mitochondrial reactive oxygen species production and its perturbation in ischaemia Biochemical Journal 436 2011 493 505
    • (2011) Biochemical Journal , vol.436 , pp. 493-505
    • Pasdois, P.1    Parker, J.E.2    Griffiths, E.J.3    Halestrap, A.P.4
  • 23
    • 33749241899 scopus 로고    scopus 로고
    • Anthocyanins: Structural characteristics that result in unique metabolic patterns and biological activities
    • R.L. Prior, and X. Wu Anthocyanins: structural characteristics that result in unique metabolic patterns and biological activities Free Radical Research 40 2006 1014 1028
    • (2006) Free Radical Research , vol.40 , pp. 1014-1028
    • Prior, R.L.1    Wu, X.2
  • 25
    • 0000168750 scopus 로고
    • Mitochondrial complexes I, II, III, IV and v in myocardial ischemia and autolysis
    • W. Rouslin Mitochondrial complexes I, II, III, IV and V in myocardial ischemia and autolysis American Journal of Physiology 244 1983 H743 H748
    • (1983) American Journal of Physiology , vol.244
    • Rouslin, W.1
  • 26
    • 0020110270 scopus 로고
    • Kinetic studies on the reduction of cytochrome c
    • M.M.M. Saleem, and M.T. Wilson Kinetic studies on the reduction of cytochrome c Biochemical Journal 201 1982 433 444
    • (1982) Biochemical Journal , vol.201 , pp. 433-444
    • Saleem, M.M.M.1    Wilson, M.T.2
  • 27
    • 58649117965 scopus 로고    scopus 로고
    • Targeting STAT1 by myricetin and delphinidin provides effcicient protection of the heart from ischemia/reperfusion-induced injury
    • T.M. Scarabelli, S. Marotto, S. Abdel-Azeim, K. Shoji, E. Darra, and A. Stephanou Targeting STAT1 by myricetin and delphinidin provides effcicient protection of the heart from ischemia/reperfusion-induced injury FEBS Letters 583 2009 531 541
    • (2009) FEBS Letters , vol.583 , pp. 531-541
    • Scarabelli, T.M.1    Marotto, S.2    Abdel-Azeim, S.3    Shoji, K.4    Darra, E.5    Stephanou, A.6
  • 28
    • 1142285456 scopus 로고    scopus 로고
    • Nitric oxide in myocardial ischemia/reperfusion injury
    • R. Schulz, M. Kelm, and G. Heusch Nitric oxide in myocardial ischemia/reperfusion injury Cardiovascular Research 61 2004 402 413
    • (2004) Cardiovascular Research , vol.61 , pp. 402-413
    • Schulz, R.1    Kelm, M.2    Heusch, G.3
  • 29
    • 33646711480 scopus 로고    scopus 로고
    • Protective effect of anthocyanins in middle cerebral artery occlusion and reperfusion model of cerebral ischemia in rats
    • W.H. Shin, S.J. Park, and E.J. Kim Protective effect of anthocyanins in middle cerebral artery occlusion and reperfusion model of cerebral ischemia in rats Life Sciences 79 2006 130 137
    • (2006) Life Sciences , vol.79 , pp. 130-137
    • Shin, W.H.1    Park, S.J.2    Kim, E.J.3
  • 30
    • 29144432723 scopus 로고    scopus 로고
    • Suppression of the pro-apoptotic function of cytochrome c by singlet oxygen via a heme redox state-independent mechanism
    • D. Suto, K. Sato, Y. Ohba, T. Yoshimura, and J. Fuji Suppression of the pro-apoptotic function of cytochrome c by singlet oxygen via a heme redox state-independent mechanism Biochemical Journal 392 2005 399 406
    • (2005) Biochemical Journal , vol.392 , pp. 399-406
    • Suto, D.1    Sato, K.2    Ohba, Y.3    Yoshimura, T.4    Fuji, J.5
  • 32
    • 41549105054 scopus 로고    scopus 로고
    • Chronic dietary intake of plant-derived anthocyanins protect the rat heart against ischemia-reperfusion injury
    • M.C. Toufektsian, M. de Lorgeril, N. Nagy, P. Salen, M.B. Donati, and L. Giordano Chronic dietary intake of plant-derived anthocyanins protect the rat heart against ischemia-reperfusion injury Journal of Nutrition 138 2008 747 752
    • (2008) Journal of Nutrition , vol.138 , pp. 747-752
    • Toufektsian, M.C.1    De Lorgeril, M.2    Nagy, N.3    Salen, P.4    Donati, M.B.5    Giordano, L.6
  • 33
    • 0032930287 scopus 로고    scopus 로고
    • Absorption and metabolism of cyaniding 3-O-beta-d-glucoside in rats
    • T. Tsuda, F. Horio, and T. Osawa Absorption and metabolism of cyaniding 3-O-beta-d-glucoside in rats FEBS Letters 449 1999 179 182
    • (1999) FEBS Letters , vol.449 , pp. 179-182
    • Tsuda, T.1    Horio, F.2    Osawa, T.3
  • 34
    • 57049132739 scopus 로고    scopus 로고
    • Glucose metabolism inhibits apoptosis in neurons and cancer cells by redox inactivation of cytochrome c
    • A.E. Vaughn, and M. Deshmukh Glucose metabolism inhibits apoptosis in neurons and cancer cells by redox inactivation of cytochrome c Nature Cell Biology 10 2008 1477 1483
    • (2008) Nature Cell Biology , vol.10 , pp. 1477-1483
    • Vaughn, A.E.1    Deshmukh, M.2
  • 35
    • 3543034002 scopus 로고    scopus 로고
    • Upregulation of endothelial nitric oxide synthase by cyanidin-3- glucoside, a typical anthocyanin pigment
    • J.W. Xu, K. Ikeda, and Y. Yamori Upregulation of endothelial nitric oxide synthase by cyanidin-3-glucoside, a typical anthocyanin pigment Hypertension 44 2004 217 222
    • (2004) Hypertension , vol.44 , pp. 217-222
    • Xu, J.W.1    Ikeda, K.2    Yamori, Y.3
  • 36
    • 0031036872 scopus 로고    scopus 로고
    • Prevention of apoptosis by Bcl-2: Release of cytochrome c from mitochondria blocked
    • J. Yang, X. Liu, K. Bhalla, C.N. Kim, A.M. Ibrado, and J. Cai Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked Science 275 1997 1129 1132
    • (1997) Science , vol.275 , pp. 1129-1132
    • Yang, J.1    Liu, X.2    Bhalla, K.3    Kim, C.N.4    Ibrado, A.M.5    Cai, J.6
  • 37
    • 33846808961 scopus 로고    scopus 로고
    • Protective activities of Vaccinium antioxidants with potential relevance to mitochondrial dysfunction and neurotoxicity
    • Y. Yao, and A. Vieira Protective activities of Vaccinium antioxidants with potential relevance to mitochondrial dysfunction and neurotoxicity Neurotoxicology 28 2007 93 100
    • (2007) Neurotoxicology , vol.28 , pp. 93-100
    • Yao, Y.1    Vieira, A.2
  • 38
    • 78649906350 scopus 로고    scopus 로고
    • Acute cardioprotective and cardiotoxic effect of bilberry anthocyanins in ischemia-reperfusion injury: Beyond concentration-dependent antioxidant activity
    • L. Ziberna, M. Lunder, S. Moze, A. Vanzo, F. Tramer, and S. Passasmonti Acute cardioprotective and cardiotoxic effect of bilberry anthocyanins in ischemia-reperfusion injury: beyond concentration-dependent antioxidant activity Cardiovascular Toxicology 10 2010 283 294
    • (2010) Cardiovascular Toxicology , vol.10 , pp. 283-294
    • Ziberna, L.1    Lunder, M.2    Moze, S.3    Vanzo, A.4    Tramer, F.5    Passasmonti, S.6


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