Collecting arthropod and amphibian secretions for chemical analyses

Behavioral and Chemical Ecology

Volumn , Issue , 2013, Pages 1-44

  Clark, Valerie C ^a  

^a QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

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EID: 84870678890     PISSN: None     EISSN: None     Source Type: Book    
DOI: None     Document Type: Chapter

References (150)

1. Anastasi, A., Erspamer, V. & Bertaccini, G. (1965). Occurrence of bradykinin in the skin of Rana temporaria Comp. Biochem. Physiol., 14, 43-52.
2. Anastasi, A., Erspamer, V. & Bucci, M. (1972). Isolation and amino acid sequence of alytesin and bombesin, two analogous active tetradecapeptides from the skin of European discoglossid frogs Arch. Biochem. Biophys., 148, 443-446.
3. Anastasi, A., Erspamer, V. & Endean. R. (1938). Isolation and amino acid sequence of caerulein, the active peptide in the skin of Hyla (Litoria) caerulea Arch. Biochem. Biophys., 125, 57-68.
4. Anastasi, A. M., Angelucci, P., F., Erspamer, V. & Endean, R. (1977). Glu(OMe)2-litorin, the second bombesin-like peptide occurring in methanol extracts of the skin of the Australian frog Litoria aurea Experientia, 33, 1289.
5. Anderson, I. G., Briggs, T. Haslewood, G. A. D., Oldham, R. S. & L. Tokes. (1979). Comparison of the bile salts of frogs with those of their tadpoles Biochem. J., 183, 507-511.
6. Aneshansley, D. J., Eisner, T. Widom, J. M. & Widom, B. (1969). Biochemistry at 100 ° explosive secretory discharge of bombardier beetles (Brachionus) Science, 165, 61-63.
7. Arthur, C. L. & Pawliszyn. J. (1990). Solid phase microextraction with thermal desorption using fused silica optical fibers Anal. Chem., 62, 2145-2148.
8. Attygalle, A. B., Svatos, A. Wilcox, C. & Voerman, S. (1994). Gas-phase infrared spectroscopy for determination of double bond configuration of monounsaturated compounds Anal. Chem., 66, 1696-1703.
9. Augusto, F. & Valente, & A. L. P. (2002). Applications of solid-phase microextraction to chemical analysis of live biological samples TrAC, 21, 428-438.
10. Barra, D. M. G., Simmaco M., Pucci, P., Severini, C., Falconieri-Erspamer, G., Negri, L, & Erspamer, V. (1994). [D-Leu2]deltorphin, a 17 amino acid opioid peptide from the skin of the Brazilian hylid frog, Phyllomedusa burmeisteri Peptides, 15, 199-202.
11. Beneski, J. T., Jr. (1989). Adaptive significance of tail autotomy in the salamander, Ensatina J. Herp., 23, 322-324.
12. Bevins, C. L. & Zasloff, M. (1990). Peptides from Frog Skin Annual Review of Biochemistry, 59, 395-414.
13. Birkett, M. & Pickett, J. (2003). Aphid sex pheromones: from discovery to commercial production Phytochemistry, 62, 651-656.
14. Brodie, E. D., Hensel, J. L. & Johnson, J. A. (1974). Toxicity of the urodele amphibians Taricha, Notophthalmus, Cynops, and Paramesotriton (Salamandridae) Copeia, 2, 506-511.
15. Brodie, E. D., III. (1993). Differential avoidance of coral snake banded patterns by free-ranging avian predators in Costa Rica Evolution, 47, 227-235.
16. Brucker, R. M., Baylor, C. M. Walters, R. L. Lauer, A. Harris, R. N. & Minbiole, K. P. C. (2008a). The identification of 2.4-diacetylphloroglucinol as an antifungal metabolite produced by cutaneous bacteria of the salamander Plethodon cinereus J. Chem. Ecol., 34, 39-43.
17. Brucker, R. M., Harris, R. N. Schwantes, C. R. Gallaher, T. N. Flaherty, D. C. Lam, B. A. & K. P. C. Minbiole. (2008b). Amphibian chemical defense: antifungal metabolites of the microsymbiont Janthinobacterium lividum on the salamander Plethodon cinereus J. Chem. Ecol., 34, 1422-1429.
18. Cerovsky, V., Pohl, J. Yang, Z. Alam, N. & Attygalle, A. B. (2007). Identification of three novel peptides isolated from the venom of the Neotropical social wasp, Polistes major major J. Pept. Sci., 13, 445-450.
19. Chen, T., Bjourson, A. J., McClean, S., Orr, D. F., O'Kane, E. J., Rao, P. & Shaw, C. (2003). Cloning of maximakinin precursor cDNAs from the Chinese toad, Bombina maxima, venom Peptides, 24, 853-861.
20. Chen, T., Orr, D. F., Bjourson, A. J., McClean, S., O'Rourke, M., Hirst, D. G., Rao, P. & Shaw. C. (2002). Bradykinins and their precursor cDNAs from the skin of the fire-bellied toad, Bombina orientalis Peptides, 23, 1547-1555.
21. Chen, T., Orr, D. F., O'Rourke, M., McGlynn, C., Bjourson, A. J., McClean, S., Hirst, D. G., Rao, P. & Shaw, C. (2004). Pachymedusa dacnicolor tryptophyllin-1 (PdT-1): structural characterization, pharmacological activity and cloning of precursor cDNA Regul. Peptides, 117, 25-32.
22. Chen, T. & Shaw, C. (2003). Cloning of the (Thr6)-phyllokinin precursor from Phyllomedusa sauvagei skin confirms a non-consensus tyrosine 0-sulfation motif Peptides, 24, 1123-1130.
23. Chen, T., Tang, L. & Shaw, C. (2003). Identification of three novel Phyllomedusa sauvagei dermaseptins (sVI-sVIII) by cloning from a skin secretion-derived cDNA library Regul. Peptides, 116, 139-146.
24. Chen, T., Walker, B., Zhou, M. & Shaw, C. (2005). Dermatoxin and phylloxin from the waxy monkey frog, Phyllomedusa sauvagei: cloning of precursor cDNAs and structural characterization from lyophilized skin secretion Regul. Pept., 129, 103-108.
25. Chen, T., Zhou, M., Rao, P., Walker, B. & Shaw, C. (2006). The Chinese bamboo leaf odorous frog (Odorrana versabilis) and North American Rana frogs share the same families of skin antimicrobial peptides Peptides, 27, 1738-1744.
26. Chen, T., Zhou, M., Gagliardo, R., Walker, B. & Shaw, C. (2006b). Elements of the granular gland peptidome and transcriptome persist in air-dried skin of the South American orange-legged leaf frog, Phyllomedusa hypocondrialis Peptides, 27, 2129-2136.
27. Clardy, J. & Walsh, C. (2004). Lessons from natural molecules Nature, 432, 829-837.
28. Clark, B. R., Engene, N., Teasdale, M. E., Rowley, D. C., Matainaho, T., Valeriote, F. A. & Gerwick, W. H. (2008). Natural products chemistry and taxonomy of the marine cyanobacterium Blennothrix cantharidosmum J. Nat. Prod., 71, 1530-1537.
29. Clark, V. C., Rakotomalala, V. Ramilijoana, O. Abrell, L. & Fisher, B. L. (2006). Individual variation in alkaloid content of poison frogs of Madagascar (Mantella; Mantellidae) Journal of Chemical Ecology, 32, 2219-2233.
30. Clark, V. C., Raxworthy, C. J., Rakotomalala, V., Sierwald, P. & Fisher, B. L. (2005). Convergent evolution of chemical defense in poison frogs and arthropod prey between Madagascar and the Neotropics Proceedings of the National Academy of Sciences, USA, 102, 11617-11622.
31. Cragg, G. M., Grosthaus, P. G. & Newman, D. J. (2009). Impact of natural products on developing new anti-cancer agents Chem. Rev., 109, 3012-3043.
32. Dalisay, D. S., Rogers, E. W. Edison, A. S. & Molinski, T. F. (2009). Structure Elucidation at the Nanomole Scale 1. Trisoxazole Macrolides and Thiazole-Containing Cyclic Peptides from the Nudibranch Hexabranchus sanguineus. J. Nat. Prod., 72, 732-738.
33. Daly, J. W. (2004). Marine Toxins and Nonmarine Toxins: Convergence or Symbiotic Organisms? J Nat. Prod., 67, 1211-1215.
34. Daly, J. W., Andriamaharavo, N. R., Andriantsiferana, M. & Myers, C. W. (1996). Madagascan poison frogs (Mantella) and their skin alkaloids Amer. Mus. Novitates, 3177, 1-34.
35. Daly, J. W., Garraffo, H. M., Hall, G. S. & Cover Jr., J. F. (1997). Absence of skin alkaloids in captive-raised madagascan mantelline frogs (Mantella) and sequestration of dietary alkaloids Toxicon, 35, 1131-5.
36. Daly, J. W., Garraffo, H. M. & Spande, T. F. (1999). Alkaloids from Amphibian Skins. Alkaloids: Chemical and Biological Perspectives. S. W. Pelletier. New York, Pergamon. 13, 1-161.
37. Daly, J. W., Garraffo, H. M., Spande, T. F., Clark, V. C., Ma, J., Ziffer, H. & Cover Jr., J. F. (2003). Evidence for an enantioselective pumiliotoxin 7-hydroxylase in dendrobatid poison frogs of the genus Dendrobates Proc. Natl. Acad. Sci. USA, 100, 11092-11097.
38. Daly, J. W., Garraffo, H. M., Pannell, L. K. & Spande, T. F. (1990). Alkaloids from Australian frogs (Myobatrachidae): Pseudophrynamines and pumiliotoxins J. Nat. Prod., 53, 407-421.
39. Daly, J. W., Garraffo, H. M., Spande, T. F., Giddings, L. A., Saporito, R. A., Vieites, D. R., & Vences, M. (2008). Geographic variation of skin alkaloids among individuals of three species of Madagascan poison frogs (Mantella) J. Chem. Ecol., 34, 252-279.
40. Daly, J. W., Kaneko, T., Wilham, J., Garraffo, H. M., Spande, T. F., Espinosa, A. & Donnelly, M. A. (2002). Bioactive alkaloids of frog skin: Combinatorial bioprospecting reveals that pumiliotoxins have an arthropod source Proc. Natl. Acad. Sci. USA, 99, 13996-14001.
41. Daly, J. W., Myers, C. W., Warnick, J. E. & Albuquerque, E. X. (1980). Levels of batrachotoxin and lack of sensitivity to its action in poison-dart frogs (Phyllobates) Science, 208, 1383-5.
42. Daly, J. W., Noimai, N., Kongkathip, B., Kongkathip, N., Wilham, J. M., Garraffo, H. M., Kaneko, T. Spande, T. F. Nimit, Y. Nabhitabhata, J. & Chan-Ard, T. (2004b). Biologically active substances from amphibians: preliminary studies on anurans from twenty-one genera of Thailand Toxicon, 44, 805-815.
43. Daly, J. W., Secunda, S. I., Garraffo, H. M., Spande, T. F., Wisneiski, A., Nishihira, C. & Cover, J. F. (1992). Variability in alkaloid profiles in Neotropical poison frogs (Dendrobatidae): genetic versus environmental determinants Toxicon, 30, 887-98.
44. Daly, J. W., Secunda, S. I. Garraffo, H. M. Spande, T. F. Wisnieski, A. & Cover, J. F. Jr. (1994). An uptake system for dietary alkaloids in poison frogs (Dendrobatidae) Toxicon, 32, 657-63.
45. Daly, J. W., Spande, T. F. & Garraffo, H. M. (2005). Alkaloids from Amphibian Skin: A Tabulation of Over Eight-Hundred Compounds J. Nat. Prod., 68, 1556-1575.
46. Daly, J. W., Tokuyama, T., Fujiwara, T., Highet, R. J. & Karle, I. L. (1980). A new class of indolizidine alkaloids from the poison frog, Dendrobates (Epipedobates) tricolor X-ray analysis of 8-hydroxy-8-methyl-6-(2'-methylhexylidene)-1-azabicyclo[4.3.0]nonane. J. Am. Chem. Soc., 102, 830-836.
47. De Lima, M. E., Figueiredo, S. G., Pimenta, A. M. C., Santos, D. M., Borges, M. H., Cordeiro, M. N., Richardson, M., Oliveira, L. C., Stankiewicz, M. & Pelhate, M. (2007). Peptides of arachnid venoms with insecticidal activity targeting sodium channels Comparative biochemistry and physiology. Toxicology & pharmacology, 146, 264-279.
48. Dettner, K. (1987). Chemosystematics and evolution of beetle chemical defenses Ann. Rev. Entomol., 32, 17-48.
49. Dossey, A. T., Walse, S. S., Conle, O. V. & Edison, A. S. (2007). Parectadial, a Monoterpenoid from the Defensive Spray of Parectatosoma mocquerysi Journal of Natural Products, 70, 1335-1338.
50. Dossey, A. T., Walse, S. S. & Edison, A. S. (2008). Developmental and geographical variation in the chemical defense of the walkingstick insect Anisomorpha buprestoides J. Chem. Ecol., 34, 584-590.
51. Dossey, A. T., Walse, S. S., Rocca, J. R. & Edison, A. S. (2006). Single Insect NMR: A New Tool to Probe Chemical Biodiversity ACS Chem. Biol., 1, 512-514.
52. du Plessis, J. L. (2005). Collection of venom from southern African scorpions Toxicon, 45, 681-682.
53. du Plessis, L. H., Elgar, D. & du Plessis, J. L. (2008). Southern African scorpion toxins: an overview Toxicon, 51, 1-9.
54. Dumbacher, J. P., Beehler, B. M. Spande, T. F. Garraffo, H. M. & Daly, J. W. (1992). Homobatrachotoxin in the genus Pitohui: chemical defense in birds? Science, 258, 799-801.
55. Dumbacher, J. P., Spande, T. F. & Daly, J. W. (2000). Batrachotoxin alkaloids from passerine birds: a second toxic bird genus (Ifrita kowaldi) from New Guinea Proc. Natl. Acad. Sci. USA, 97, 12970-75.
56. Dumbacher, J. P., Wako, A., Derrickson, S. R., Samuelson, A., Spande, T. F. & Daly, J. W. (2004). Melyrid beetles (Choresine): A putative source for the batrachotoxin alkaloids found in poison-dart frogs and toxic passerine birds Proc. Nat. Acad. Sci. USA., 101, 15857-15860.
57. Eisner, T. (2003). For Love of Insects. Cambridge, MA.Harvard University Press.
58. Eisner, T., Alsop, D. Hicks, K. & Meinwald, J. (1978). Defensive secretions of millipeds Handbuch der Experimentellen Pharmakologie, 48, 41-72.
59. Eisner, T., Eisner, M. & Siegler, M. (2007). Secret Weapons: Defenses of Insects, Spiders, Scorpions, and Other Many-Legged Creatures Cambridge, MA.Belknap Press of Harvard University Press.
60. Eisner, T. & Meinwald, J. (1995). Chemical Ecology: The Chemistry of Biotic Interaction Washington, D.C.National Academy of Sciences.
61. Eisner, T., Meinwald, Y. C. A. & Carrel, J. E. (1968). Defense mechanisms of arthropods XXI. Formic acid and n-nonyl acetate in the defensive spray of two species of Helluomorphoides. Annals of the Entomological Society of America, 61, 610-613.
62. Eisner, T., Morgan, R. C., Attygalle, A. B., Smedley, S. R., Herath, K. B. & Meinwald, J. (1997). Defensive production of quinoline by a phasmid insect (Oreophoetes peruana). J. Exp. Biol., 200.
63. Erspamer, V. (1994). Bioactive secretions of the amphibian integument. Amphibian Biology, Vol. 1, The Integument. G. Heatwole, T. Barthalmus and A. T. Heatwole, Surrey Beatty and Sons, Chipping Norton: 178-350.
64. Erspamer V., Anastasi, A., Bertacinni, G. & Cei, J. M. (1964). Structure and pharmacological actions of physalaemin, the main active polypeptide of the skin of Physalaemus fuscomaculatus Experientia, 20, 489-490.
65. Fenn, J. B., Mann, M., Meng, C. K., Wong, S. F. & Whitehouse, C. M. (1989). Electrospray ionization for mass spectrometry of large biomolecules Science, 246, 64-71.
66. Frost, D. R. (2009). Amphibian Species of the World: an Online Reference, Electronic Database accessible at http://research.amnh.org/herpetology/amphibia/American Museum of Natural History, New York, USA.
67. Gaertner, L. S., Murray, C. L. & Morris, C. E. (1998). Transepithelial transport of nicotine and vinblastine in isolated Malpighian tubules of the tobacco hornworm (Manduca sexta) suggests a P-glycoprotein-like mechanism J. Exp. Biol., 201, 2637-45.
68. Garraffo, H. M., Spande, T. F., Daly, J. W., Baldessari, A. & Gros, E. G. (1993). Alkaloids from bufonid toads (Melanophryniscus): Decahydroquinolines, pumiliotoxins and homopumiliotoxins, indolizidines, pyrrolizidines, and quinolizidines J. Nat. Prod., 56, 357-373.
69. Gibson, B. W., Poulter, L., Williams, D. H. & Maggio, J. E. (1986). Novel peptide fragments originating from PGLa and the caerulein and xenopsin precursors from Xenopus laevis J. Biol. Chem., 261, 5341-5349.
70. Goncalves, V. F. & de Brito-Gitirana, L. (2008). Structure of the sexually dimorphic gland of Cycloramphus fuliginosus (Amphibia, Anura, Cycloramphidae) Micron, 39, 32-39.
71. Graham, L. D., Glattauer, V., Huson, M. G., Maxwell, J. M., Knott, R. B., White, J. W., Vaughan, P. R., Peng, Y., Tyler, M. J., Werkmeister, J. A. & Ramshaw J. A. (2005). Characterization of a protein-based adhesive elastomer secreted by the Australian frog Notaden bennetti Biomacromolecules, 6, 3300-3312.
72. Grant, J. B. & Land, B. (2002). Transcutaneous Amphibian Stimulator (TAS): A device for the collection of amphibian skin secretions Herp. Rev., 33, 38-41.
73. Grant, T., Frost, D. R., Caldwell, J. P., Gagliardo, R., Haddad, C. F. B., Kok, P. J. R., Means, D. B., Noonan, B. P., Schargel, W. E. & Wheeler, W. C. (2006). Phylogenetic systematics of dart-poison frogs and their relatives (Amphibia: Athesphatanura: Dendrobatidae) Bull. Amer. Mus. Novitates, 299, 1-262.
74. Gusovsky, F., Hollingsworth, E. B. & Daly, J. W. (1986). Regulation of phosphatidylinositol turnover in brain synaptoneurosomes: stimulatory effects of agents that enhance influx of sodium ions Proc. Nat. Acad. Sci. USA., 83, 3003-3007.
75. Hartmann, T. & Ober, D. (2000). Biosynthesis and metabolism of pyrrolizidine alkaloids in plants and specialized insect herbivores Topics in Curr. Chem., 209, 207-43.
76. Hartmann, T. & Ober, D. (2008). Defense by pyrrolizidine alkaloids: developed by plants and recruited by insects. Induced Plant Resistance to Herbivory. A. Schaller, Springer: 213-231.
77. Haynes, K. F. & Yeargan. K. V. (1999). Exploitation of intraspecific communication systems: Illicit signalers and receivers Annals of the Entommological Society of America, 92, 960-970.
78. Houck, L. D. (2009). Pheromone Communication in Amphibians and Reptiles Annual Review of Physiology, 71, 161-176.
79. Hutchinson, D. A., Mori, A., Savitzky, A. H., Burghardt, G. M. X. Wu, G. M., Meinwald, J. & Schroeder, F. (2007). The Dietary Sequestration of Defensive Steroids in Nuchal Glands of the Asian Snake Rhabdophis tigrinus Proc. Nat. Acad. Sci. USA., 104, 2265-2270.
80. Jilek, A., Mollay, C., Tippelt, C., Grassi, J., Mignogna, G., Muellegger, J., Sander, V. Fehrer, C., Barra, D. & Kreil, G. (2005). Biosynthesis of a D-amino acid in peptide linkage by an enzyme from frog skin secretions Proc. Nat. Acad. Sci. USA, 102, 4235-4239.
81. Kikuyama, S., Toyoda, F., Ohmiya, Y., Matsuda, K., Tanaka, S. & Hayashi, H. (1995). Sodefrin: a female attracting peptide pheromone in newt cloacal glands Science, 267, 1643-1645.
82. King, A. G. & Meinwald, J. (1996). Review of the defensive chemistry of Coccinellids Chem. Rev., 96, 1105-22.
83. Krenn, L. & Kopp, B. (1998). Bufadienolides from animal and plant sources Phytochemistry, 48, 1-29.
84. Kuchta, S. R. (2005). Experimental support for aposematic coloration in the salamander Ensatina eshcshcoltzii xanthoptica: implications for mimicry of pacific newts Copeia, 2005, 265-271.
85. Kuchta, S. R., Krakauer, A. H. & Sinervo, B. (2008). Why does the yellow-eyed Ensatina have yellow eyes? Batesian mimicry of pacific newts (genus Taricha) by the salamander Ensatina eschscholtzii xanthoptica Evolution, 62, 984-990.
86. Kuramoto, T., Kikuchi, H., Sanemori, H. & Hoshita, T. (1973). Bile salts of anura Chem. Pharm. Bull., 21, 952-959.
87. Laurent, P., Braekman, J. C. & Daloze, D. (2005). Insect Chemical Defense Topics Curr. Chem., 240, 167-229.
88. Leclercq, S., Braekman, J. C., Daloze, D. & Pasteels, J. M. (2000). The defensive chemistry of ants Progress in the Chemistry of Organic Natural Products, 79, 115-229.
89. Lips, K. R., Brem, F., Brenes, R., Reeve, J. D., Alford, R. A., Voyles, J., Cynthia Carey, C., Livo, L. Pessier, A. P. & Collins, J. P. (2006). Emerging infectious disease and the loss of biodiversity in a Neotropical amphibian community Proc. Nat. Acad. Sci. USA., 103, 3165-3170.
90. Marenah, L., Shaw, C., Orr, D. F., McClean, S., Flatt, P. R. & Abdel-Wahab, Y. H. A. (2004). Isolation and characterisation of an unexpected class of insulinotropic peptides from the skin of the frog, Agalychnis litodryas Regul. Peptides, 120, 33-38.
91. Marshall, A. G., Hendrickson, C. L. & Jackson, G. S. (1998). Fourier Transform Ion Cyclotron Mass Spectrometry: A Primer Mass Spectrom Rev, 17, 1-35.
92. Means, D. B., Duellman, W. E. & Clark, V. C. (2008). Ovipositing behavior of the egg-brooding frog Stefania ayangannae (Anura, Hemiphractidae) Phyllomedusa, 7, 143-148.
93. Mebs, D., Pogoda, W., Maneyro, R. & Kwet, A. (2005). Studies on the poisonous skin secretion of individual red bellied toads, Melanophyrniscus montevidensis (Anura, Bufonidae), from Uruguay Toxicon, 46, 641-650.
94. Meinwald, J. & Eisner, T. (2008). Chemical ecology in retrospect and prospect Proc. Nat. Acad. Sci. USA., 105, 4539-4540.
95. Meinwald, J., Chadha, M. S., Hurst, J. J. & Eisner, T. (1962). Defense mechanisms of arthropods-IX anisomorphal, the secretion of a phasmid insect Tet. Lett., 3, 29-33.
96. Mignogna, G., Simmaco, M., Kreil, G. & Barra, D. (1993). Antibacterial and haemolytic peptides containing D-alloisoleucine from the skin of Bombina variegata EMBO J., 12, 4829-4832.
97. Mollay, C., Wichta, J. & Kreil, G. (1986). Detection and partial characterization of an amidating enzyme in skin secretion of Xenopus laevis FEBS Letters, 202, 251-254.
98. Montecucchi, P. C., de Castiglione, R. & Erspamer, V. (1981). Identification of dermorphin and Hyp-6-dermorphin in skin extracts of the Brazilian frog "Phyllomedusa rhodei" Int. J. Peptide Protein Research, 17, 316-321.
99. Montecucchi, P. C., De Castiglione, R., Piani, S., Gozzini, L. & Erspamer, V. (1981). Amino acid composition and sequence of dermorphin, a novel opiate-like peptide from the skin of Phyllomedusa sauvagei Int. J. Peptide Protein Res., 17, 275-283.
100. Myers, C. W. & Daly, J. W. (1980). Taxonomy and ecology of Dendrobates (Minyobates) bombetes, a new Andean poison frog with new skin toxins American Museum. Novitates, 2692, 1-23.
101. Myers, C. W. & Daly, J. W. (1993). Tropical poison frogs Science, 262, 1193.
102. Myers, C. W., Daly, J. W. & Malkin, B. (1978). A dangerously toxic new frog (Phyllobates) used by Emberá Indians of Western Colombia, with a discussion of blowgun fabrication and dart poisoning Bulletin of the American Museum of Natural History, 161, 309-365.
103. Nakada, T., Toyoda, F., Iwata, T., Yamamoto, K, Conlon, J. M., Kato, T. & Kikuyama, S. (2007). Isolation, characterization and bioactivity of a region-specific pheromone, [Val8]sodefrin from the newt Cynops pyrrhogaster Peptides, 28, 774-780.
104. Neuwirth, M., Daly, J. W., Myers, C. W. & Tice, L. W. (1979). Morphology of the granular secretory glands in skin of poison-dart frogs (Dendrobatidae) Tissue & Cell, 11, 755-71.
105. Noma, Y., Kihira, K., Kuramoto, T. & Hoshita, T. (1998). Metabolism of bile alcohols in the bullfrog, Rana catesbeiana Steroids, 51, 385-394.
106. O'Rourke, M., Chen, T., Hirst, D. G., Rao, P. & C. Shaw. (2004). The smooth muscle pharmacology of maximakinin, a receptor-selective, bradykinin-related nonadecapeptide from the venom of the Chinese toad, Bombina maxima Regul. Pept., 121, 65-72.
107. Palma, M. S. (2006). Insect venom peptides. Handbook of Biologically Active Peptides. A. J. Kastin. Rio Claro, Brazil: 389-396.
108. Patto, C. E. (1998). A simple stomach flushing method for small frogs Herp. Rev., 29, 156-7.
109. Perry, R. H., Cooks, R. G. & Noll, R. J. (2008). Orbitrap mass spectrometry: instrumentation, ion motion and applications Mass Spectrom. Rev., 27, 661-699.
110. Pickett, J. A., Wadhams, L. J. & Woodcock, C. M. (1997). Developing sustainable pest control from chemical ecology Agriculture, Ecosystems & Environment, 64, 149-156.
111. Piek, T. (1990). Neurotoxins from venoms of the hymenoptera-twenty-five years of research in Amsterdam. Comparative Biochemistry and Physiology, Part C: Pharmacology, Toxicology & Endocrinology (1990), 96C(2), 223-33.
112. Pimenta, A. M. C. & De Lima, M. E. (2005). Small peptides, big world: biotechnological potential in neglected bioactive peptides from arthropod venoms J. Peptide Sci., 11, 670-676.
113. Pisani, D., Poling, L. L., Lyons-Weiler, M. & Hedges, S. B. (2004). The colonization of land by animals: molecular phylogeny and divergence times among arthropods. BMC Biol., 2.
114. Pounds, J. A., Bustamante, M. R., Coloma, L. A., Consuegra, J. A., Fogden, M. P., Foster, P. N., La Marca, E., Masters, K. L., Merino-Viteri, A., Puschendorf, R., Santiago, R., Sánchez-Azofeifa, G. A., Still, C. J. & Young, B. E. (2006). Widespread amphibian extinctions from epidemic disease driven by global warming Nature, 439, 162-167.
115. Pukala, T. L., Bowie, J. H., Maselli, V. M., Musgrave, I. F. & Tyler, M. J. (2006). Host-defence peptides from the glandular secretions of amphibians: structure and activity Nat. Prod. Rep., 23, 368-393.
116. Quan, Z., Zhou, M., Chen, W., Chen, T., Walker, B. & Shaw, C. (2008). Novel brevinins from Chinese piebald odorous frog (Huia schmackeri) skin deduced from cloned biosynthetic precursors Peptides, 29, 1456-1460.
117. Richter, K., Egger, R. & Kreil, G. (1987). D-alanine in the frog skin peptide dermorphin is derived from L-alanine in the precursor Science, 238, 200-202.
118. Rollins-Smith, L. A. & Conlon, J. M. (2005). Antimicrobial peptide defenses against chytridiomycosis, an emerging infectious disease of amphibian populations Developmental & Comparative Immunology, 29, 589-598.
119. Rollins-Smith, L. A., Woodhams, D. C., Reinerta, L. K., Vredenburg, V. T., Briggs, C. J., Nielsend, P. F. & Conlon, J. M. (2006). Antimicrobial peptide defenses of the mountain yellow-legged frog (Rana muscosa) Developmental and Comparative Immunology, 30, 831-842.
120. Rollmann, S. M., Houck, L. D. & Feldhoff, R. C. (1999). Proteinaceous pheromone affecting female receptivity in a terrestrial salamander Science, 285, 1907-1909.
121. Roseghini, M., Erspamer, G. F. & Severini, C. (1988). Biogenic amines and active peptides in the skin of fifty-two African amphibian species other than bufonids Comp. Biochem. Physiol., 91 C, 281-286.
122. Saiki, R. K., Gelfand, D. H., Stoffel, S., Scharf, S. J., Higuchi, R., Horn, G. T., Mullis, K. B. & Erlich, H. A. (1988). Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase Science, 239, 487-491.
123. Santa Coloma, T. A., Garraffo, H. M., Pignataro, O. P., Charreau, E. H. & Gros, E. G. (1984). Biosynthesis of bufadienolides in toads V. The origin of the cholesterol used by toad parotoid glands for biosynthesis of bufadienolides. Steroids, 4, 11-22.
124. Saporito, R. A., Donnelly, M. A., Garraffo, H. M., Spande, T. F. & Daly, J. W. (2006). Geographic and seasonal variation in alkaloid-based chemical defenses of Dendrobates pumilio from Bocas del Toro, Panama J. Chem. Ecol., 32, 795-814.
125. Saporito, R. A., Donnelly, M. A., Hoffman, R. L., Garraffo, H. M. & Daly, J. W. (2003). A siphonotid millipede (Rhinotus) as the source of spiropyrrolizidine oximes of dendrobatid frogs J. Chem. Ecol., 29, 2781-6.
126. Saporito, R. A., Donnelly, M. A., Norton, R. A., Garraffo, H. M., Spande, T. F. & Daly, J. W. (2007b). Oribatid mites as a major dietary source for alkaloids in poison frogs Proc. Nat. Acad. Sci. USA., 104, 8885-8890.
127. Saporito, R. A., Garraffo, H. M., Donnelly, M. A., Edwards, A. L., Longino, J. T. & Daly, J. W. (2004). Formicine ants: an arthropod source for the pumiliotoxin alkaloids of dendrobatid poison frogs Proc. Natl. Acad. Sci. USA, 101, 8045-50.
128. Saporito, R. A., Zuercher, R., Roberts, M., Gerrow, K. G. & Donnelly, M. A. (2007). Experimental evidence for aposematism in the poison frog Oophaga pumilio Copeia, 4, 1006-1011.
129. Schopf, C. & Bayerle, H. (1934). Liebigs Ann Chem., 513, 190-202.
130. Schroder, F. C., Farmer, J. J. A. Athula, B., Smedley Scott, R.; Eisner, Thomas, & Meinwald, J. (1998). Combinatorial chemistry in insects: a library of defensive macrocyclic polyamines Science, 281, 428-431.
131. Schroeder, F. C., Taggi, A. E. G., Matthew; Malik, Rabia U., Grant, Jacqualine, B., Eisner, T. & Meinwald, J. (2008). NMR-spectroscopic screening of spider venom reveals sulfated nucleosides as major components for the brown recluse and related species Proc. Nat. Acad. Sci. USA, 105, 14283-14287.
132. Shaw, C. & Chen, T. (2008). Analysis of the peptidomes of amphibian skin granular gland secretions-an integrated functional genomic strategy. Peptidomics: methods and applications. M. Soloviev, C. Shaw and P. Andren. Hoboken, New Jersey, John Wiley & Sons, Inc.: 3-19.
133. Sin, Y., Zhou, M., Chen, W., Wang, L., Chen, T., Walker, B. & Shaw, C. (2008). Skin bradykinin-related peptides (BRPs) and their biosynthetic precursors (kininogens): comparisons between various taxa of Chinese and North American ranid frogs Peptides, 29, 393-403.
134. Smith, B. P., Tyler, M. J., Kaneko, T., Garraffo, H. M., Spande, T. F. & Daly, J. W. (2002). Evidence for biosynthesis of pseudophrynamine alkaloids by an Australian Myobatrachid frog (Pseudophryne) and for the sequestration of dietary pumiliotoxins Journal of Natural Products, 65, 439-447.
135. Stuart, S. N., Chanson, J. S., Cox, N. A., Young, B. E., Rodrigues, A. S. L., Fischman, D. L. & Waller, R. W. (2004). Status and trends of amphibian declines and extinctions worldwide Science, 306, 1783-1786.
136. Takada, W., T., Sakata, S., Shimano, Y., Enami, N., Mori, Nishida, R. & Kuwahara, Y. (2005). Scheloribatid mites as the source of pumiliotoxins in dendrobatid frogs J. Chem. Ecol., 31, 2403-2415.
137. Tempone, A. G., Pimenta, D. C., Lebrun, I., Sartorelli, P., Taniwaki, N. N., de Andrade, H. F., Jr., Antoniazzi, M. M. & Jared, C. (2008). Antileishmanial and antitrypanosomal activity of bufadienolides isolated from the toad Rhinella jimi parotoid macrogland secretion Toxicon, 52, 13-21.
138. Thompson, A. H., Bjourson, A. J., Orr, D. F., Shaw, C. & McClean, S. (2007). Amphibian skin secretomics: application of parallel quadrupole time-of-flight mass spectrometry and peptide precursor cDNA cloning to rapidly characterize the skin secretory peptidome of Phyllomedusa hypochondrialis azurea: discovery of a novel peptide family, the hyposins J. Proteome Res, 6, 3604-3613.
139. Toki, T., Yasuhara, T. & Nakajima, T. (1988). Isolation and sequential analysis of peptides on the venom sac of Parapolybia indica Eisei Dobutsu, 39, 105-111.
140. Tyler, M. J., Stone, D. J. M. & Bowie, J. H. (1992). A novel method for the release and collection of dermal, glandular secretions from the skin of frogs J. Pharm. Toxicol. Methods, 28, 199-200.
141. Wabnitz, P. A., Bowie, J. H. Tyler, M. J. Wallace, J. C. & Smith, B. P. (1999). Animal behaviour: Aquatic sex pheromone from a male tree frog Nature, 40, 444-445.
142. Wake, D. B. & Dresner, I. G. (1967). Functional morphology and evolution of tail autotomy in salamanders J. Morph., 122, 265-306.
143. Ward, J. L., Baker, J. M. & Beale, M. H. (2007). Recent applications of NMR spectroscopy in plant metabolomics FEBS Journal, 274, 1126-1131.
144. Wolfe, S., Bernhard Schlegel, H,, Whangbo, M. & Bernardi, F. (1974). On the origin of Bohlmann bands Can. J. Chem., 52, 3787-3792.
145. Yotsu-Yamashita, M., Kim, Y. H., Dudley, Jr., S. C., Choudhary, G., Pfahnl, A., Oshima, Y. & Daly, J. W. (2004). The structure of zetekitoxin AB, a saxitoxin analog from the Panamanian golden frog Atelopus zeteki: A potent sodium-channel blocker Proc. Nat. Acad. Sci. USA., 101, 4346-4351.
146. Yotsu-Yamashita, M. & Mebs, D. (2003). Occurrence of 11-oxotetrodotoxin in the red-spotted newt, Notophthalmus viridescens, and further studies on the levels of tetrodotoxin and its analogues in the newt's efts Toxicon, 41, 893-897.
147. Zasloff, M. (2002). Antimicrobial peptides of multicellular organisms Nature, 415, 389-395.
148. Zhou, M., Chen, T., Walker, B. & Shaw, C. (2006a). Pelophylaxins: novel antimicrobial peptide homologs from the skin secretion of the Fukien gold-striped pond frog, Pelophylax plancyi fukienensis: identification by-shotgun cDNA cloning and sequence analysis Peptides, 27, 36-41.
149. Zhou, M., Chen, T., Walker, B. & Shaw, C. (2006b). Lividins: novel antimicrobial peptide homologs from the skin secretion of the Chinese Large Odorous frog, Rana (Odorrana) livida: identification by-shotgun cDNA cloning and sequence analysis Peptides, 27, 2118-2123.
150. Zhou, M., Liu, Y., Chen, T., Fang, X., Walker, B. & Shaw, C. (2006c). Components of the peptidome and transcriptome persist in lin wa pi: the dried skin of the Heilongjiang Brown frog (Rana amurensis) as used in Traditional Chinese medicine Peptides, 27, 2688-2694.