Antileishmanial and antitrypanosomal activity of bufadienolides isolated from the toad Rhinella jimi parotoid macrogland secretion

Toxicon

Volumn 52, Issue 1, 2008, Pages 13-21

  Tempone, André Gustavo ^a,b,c   Pimenta, Daniel Carvalho ^c   Lebrun, Ivo ^c   Sartorelli, Patrícia ^b   Taniwaki, Noemi N ^a   de Andrade Jr , Heitor Franco ^d   Antoniazzi, Marta Maria ^c   Jared, Carlos ^c  

^a INSTITUTO ADOLFO LUTZ   (Brazil)

^b FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^c INSTITUTO BUTANTAN   (Brazil)

^d UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Bufadienolides; Hellebrigenin; Leishmania; Rhinella jimi; Telocinobufagin; Trypanosoma cruzi

Indexed keywords

BUFADIENOLIDE DERIVATIVE; HELLEBRIGENIN; NITRIC OXIDE; TELOCINOBUFAGIN;

ANIMAL EXPERIMENT; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CONTROLLED STUDY; CYTOTOXICITY; DRUG ACTIVITY; DRUG INHIBITION; DRUG ISOLATION; DRUG MECHANISM; HEMOLYSIS; LEISHMANIA CHAGASI; MACROPHAGE; MOUSE; NONHUMAN; PAROTID GLAND; PRIORITY JOURNAL; PROMASTIGOTE; PROTON NUCLEAR MAGNETIC RESONANCE; TOAD; TRYPANOSOMA CRUZI;

ANIMALS; BUFANOLIDES; BUFONIDAE; CRICETINAE; LEISHMANIA INFANTUM; MACROPHAGES; MAGNETIC RESONANCE SPECTROSCOPY; MESOCRICETUS; MICE; MICE, INBRED BALB C; NITRIC OXIDE; PAROTID GLAND; TRYPANOCIDAL AGENTS; TRYPANOSOMA CRUZI;

AMPHIBIA; ANIMALIA; ANURA; LEISHMANIA DONOVANI CHAGASI; TRYPANOSOMA CRUZI;

EID: 48049119692     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxicon.2008.05.008     Document Type: Article

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