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Volumn 103, Issue 12, 2012, Pages 2082-2091

REG4 contributes to the invasiveness of pancreatic cancer by upregulating MMP-7 and MMP-9

Author keywords

[No Author keywords available]

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; GELATINASE B; MATRILYSIN; ONCOPROTEIN; REGENERATING GENE FAMILY MEMBER 4; UNCLASSIFIED DRUG;

EID: 84870660245     PISSN: 13479032     EISSN: 13497006     Source Type: Journal    
DOI: 10.1111/cas.12018     Document Type: Article
Times cited : (40)

References (32)
  • 1
    • 77951755278 scopus 로고    scopus 로고
    • Pancreatic cancer
    • Hidalgo M. Pancreatic cancer. N Engl J Med 2010; 362: 1605-17.
    • (2010) N Engl J Med , vol.362 , pp. 1605-1617
    • Hidalgo, M.1
  • 3
    • 0035897122 scopus 로고    scopus 로고
    • Isolation and characterization of a cDNA encoding a novel member of the human regenerating protein family: Reg IV
    • Hartupee JC, Zhang H, Bonaldo MF, Soares MB, Dieckgraefe BK. Isolation and characterization of a cDNA encoding a novel member of the human regenerating protein family: Reg IV. Biochim Biophys Acta 2001; 1518: 287-93.
    • (2001) Biochim Biophys Acta , vol.1518 , pp. 287-293
    • Hartupee, J.C.1    Zhang, H.2    Bonaldo, M.F.3    Soares, M.B.4    Dieckgraefe, B.K.5
  • 4
    • 61449325195 scopus 로고    scopus 로고
    • Immunohistochemical analysis of Reg IV in urogenital organs: Frequent expression of Reg IV in prostate cancer and potential utility as serum tumor marker
    • Hayashi T, Matsubara A, Ohara S et al. Immunohistochemical analysis of Reg IV in urogenital organs: Frequent expression of Reg IV in prostate cancer and potential utility as serum tumor marker. Oncol Rep 2009; 21: 95-100.
    • (2009) Oncol Rep , vol.21 , pp. 95-100
    • Hayashi, T.1    Matsubara, A.2    Ohara, S.3
  • 5
    • 1942474530 scopus 로고    scopus 로고
    • Gene expression profile of gastric carcinoma: identification of genes and tags potentially involved in invasion, metastasis, and carcinogenesis by serial analysis of gene expression
    • Oue N, Hamai Y, Mitani Y et al. Gene expression profile of gastric carcinoma: identification of genes and tags potentially involved in invasion, metastasis, and carcinogenesis by serial analysis of gene expression. Cancer Res 2004; 64: 2397-405.
    • (2004) Cancer Res , vol.64 , pp. 2397-2405
    • Oue, N.1    Hamai, Y.2    Mitani, Y.3
  • 6
    • 26044463766 scopus 로고    scopus 로고
    • Expression and localization of Reg IV in human neoplastic and non-neoplastic tissues: Reg IV expression is associated with intestinal and neuroendocrine differentiation in gastric adenocarcinoma
    • Oue N, Mitani Y, Aung PP et al. Expression and localization of Reg IV in human neoplastic and non-neoplastic tissues: Reg IV expression is associated with intestinal and neuroendocrine differentiation in gastric adenocarcinoma. J Pathol 2005; 207: 185-98.
    • (2005) J Pathol , vol.207 , pp. 185-198
    • Oue, N.1    Mitani, Y.2    Aung, P.P.3
  • 7
    • 77949262349 scopus 로고    scopus 로고
    • Serum tumor antigen REG4 as a diagnostic biomarker in pancreatic ductal adenocarcinoma
    • Takayama R, Nakagawa H, Sawaki A et al. Serum tumor antigen REG4 as a diagnostic biomarker in pancreatic ductal adenocarcinoma. J Gastroenterol 45:52-9.
    • J Gastroenterol , vol.45 , pp. 52-59
    • Takayama, R.1    Nakagawa, H.2    Sawaki, A.3
  • 8
    • 70449106220 scopus 로고    scopus 로고
    • Reg IV expression and clinicopathologic features of gallbladder carcinoma
    • Tamura H, Ohtsuka M, Washiro M et al. Reg IV expression and clinicopathologic features of gallbladder carcinoma. Hum Pathol 2009; 40: 1686-92.
    • (2009) Hum Pathol , vol.40 , pp. 1686-1692
    • Tamura, H.1    Ohtsuka, M.2    Washiro, M.3
  • 9
    • 0037427784 scopus 로고    scopus 로고
    • Reg IV, a new member of the regenerating gene family, is overexpressed in colorectal carcinomas
    • Violette S, Festor E, Pandrea-Vasile I et al. Reg IV, a new member of the regenerating gene family, is overexpressed in colorectal carcinomas. Int J Cancer 2003; 103: 185-93.
    • (2003) Int J Cancer , vol.103 , pp. 185-193
    • Violette, S.1    Festor, E.2    Pandrea-Vasile, I.3
  • 10
    • 39049171987 scopus 로고    scopus 로고
    • Serum concentration of Reg IV in patients with colorectal cancer: overexpression and high serum levels of Reg IV are associated with liver metastasis
    • Oue N, Kuniyasu H, Noguchi T et al. Serum concentration of Reg IV in patients with colorectal cancer: overexpression and high serum levels of Reg IV are associated with liver metastasis. Oncology 2007; 72: 371-80.
    • (2007) Oncology , vol.72 , pp. 371-380
    • Oue, N.1    Kuniyasu, H.2    Noguchi, T.3
  • 11
    • 70349880528 scopus 로고    scopus 로고
    • Serum olfactomedin 4 (GW112, hGC-1) in combination with Reg IV is a highly sensitive biomarker for gastric cancer patients
    • Oue N, Sentani K, Noguchi T et al. Serum olfactomedin 4 (GW112, hGC-1) in combination with Reg IV is a highly sensitive biomarker for gastric cancer patients. Int J Cancer 2009; 125: 2383-92.
    • (2009) Int J Cancer , vol.125 , pp. 2383-2392
    • Oue, N.1    Sentani, K.2    Noguchi, T.3
  • 12
    • 84870678736 scopus 로고    scopus 로고
    • Significance of serum REG4 upregulation in the diagnosis and treatment of pancreatic adenocarinoma
    • Tao HQ, He XJ, Jiang XT, Ma YY, Wang HJ, Xia YJ. Significance of serum REG4 upregulation in the diagnosis and treatment of pancreatic adenocarinoma. J Surg Concepts Pract 2010;15: 522-5.
    • (2010) J Surg Concepts Pract , vol.15 , pp. 522-525
    • Tao, H.Q.1    He, X.J.2    Jiang, X.T.3    Ma, Y.Y.4    Wang, H.J.5    Xia, Y.J.6
  • 13
    • 77149158125 scopus 로고    scopus 로고
    • REG4 acts as a mitogenic, motility and pro-invasive factor for colon cancer cells
    • Rafa L, Dessein AF, Devisme L et al. REG4 acts as a mitogenic, motility and pro-invasive factor for colon cancer cells. Int J Oncol 2010; 36: 689-98.
    • (2010) Int J Oncol , vol.36 , pp. 689-698
    • Rafa, L.1    Dessein, A.F.2    Devisme, L.3
  • 14
    • 0141638742 scopus 로고    scopus 로고
    • Overexpression of Reg IV in colorectal adenoma
    • Zhang Y, Lai M, Lv B et al. Overexpression of Reg IV in colorectal adenoma. Cancer Lett 2003; 200: 69-76.
    • (2003) Cancer Lett , vol.200 , pp. 69-76
    • Zhang, Y.1    Lai, M.2    Lv, B.3
  • 15
    • 75149140907 scopus 로고    scopus 로고
    • Reg IV regulates normal intestinal and colorectal cancer cell susceptibility to radiation-induced apoptosis
    • Bishnupuri KS, Luo Q, Sainathan SK et al. Reg IV regulates normal intestinal and colorectal cancer cell susceptibility to radiation-induced apoptosis. Gastroenterology 2010; 138: 616-26.
    • (2010) Gastroenterology , vol.138 , pp. 616-626
    • Bishnupuri, K.S.1    Luo, Q.2    Sainathan, S.K.3
  • 16
    • 79955837437 scopus 로고    scopus 로고
    • Reg4 protects against acinar cell necrosis in experimental pancreatitis
    • Hu G, Shen J, Cheng L et al. Reg4 protects against acinar cell necrosis in experimental pancreatitis. Gut 2011; 60: 820-8.
    • (2011) Gut , vol.60 , pp. 820-828
    • Hu, G.1    Shen, J.2    Cheng, L.3
  • 17
    • 16844362558 scopus 로고    scopus 로고
    • Reg IV: a promising marker of hormone refractory metastatic prostate cancer
    • Gu Z, Rubin MA, Yang Y et al. Reg IV: a promising marker of hormone refractory metastatic prostate cancer. Clin Cancer Res 2005; 11: 2237-43.
    • (2005) Clin Cancer Res , vol.11 , pp. 2237-2243
    • Gu, Z.1    Rubin, M.A.2    Yang, Y.3
  • 18
    • 80053214423 scopus 로고    scopus 로고
    • Evaluation of REG4 for early diagnosis and prognosis of gastric cancer
    • Tao HQ, He XJ, Ma YY et al. Evaluation of REG4 for early diagnosis and prognosis of gastric cancer. Hum Pathol 2011; 42: 1401-9.
    • (2011) Hum Pathol , vol.42 , pp. 1401-1409
    • Tao, H.Q.1    He, X.J.2    Ma, Y.Y.3
  • 19
    • 58449092403 scopus 로고    scopus 로고
    • Reg IV enhances peritoneal metastasis in gastric carcinomas
    • Kuniyasu H, Oue N, Sasahira T et al. Reg IV enhances peritoneal metastasis in gastric carcinomas. Cell Prolif 2009; 42: 110-21.
    • (2009) Cell Prolif , vol.42 , pp. 110-121
    • Kuniyasu, H.1    Oue, N.2    Sasahira, T.3
  • 20
    • 42549162728 scopus 로고    scopus 로고
    • Overexpression of RegIV in peritoneal dissemination of gastric cancer and its potential as A novel marker for the detection of peritoneal micrometastasis
    • Miyagawa K, Sakakura C, Nakashima S et al. Overexpression of RegIV in peritoneal dissemination of gastric cancer and its potential as A novel marker for the detection of peritoneal micrometastasis. Anticancer Res 2008; 28: 1169-79.
    • (2008) Anticancer Res , vol.28 , pp. 1169-1179
    • Miyagawa, K.1    Sakakura, C.2    Nakashima, S.3
  • 21
    • 77955717754 scopus 로고    scopus 로고
    • MicroRNA-101 is down-regulated in gastric cancer and involved in cell migration and invasion
    • Wang HJ, Ruan HJ, He XJ et al. MicroRNA-101 is down-regulated in gastric cancer and involved in cell migration and invasion. Eur J Cancer 2010; 46: 2295-303.
    • (2010) Eur J Cancer , vol.46 , pp. 2295-2303
    • Wang, H.J.1    Ruan, H.J.2    He, X.J.3
  • 22
    • 33748932541 scopus 로고    scopus 로고
    • Novel tumor marker REG4 detected in serum of patients with resectable pancreatic cancer and feasibility for antibody therapy targeting REG4
    • Takehara A, Eguchi H, Ohigashi H et al. Novel tumor marker REG4 detected in serum of patients with resectable pancreatic cancer and feasibility for antibody therapy targeting REG4. Cancer Sci 2006; 97: 1191-7.
    • (2006) Cancer Sci , vol.97 , pp. 1191-1197
    • Takehara, A.1    Eguchi, H.2    Ohigashi, H.3
  • 23
    • 70449360277 scopus 로고    scopus 로고
    • The reg4 gene, amplified in the early stages of pancreatic cancer development, is a promising therapeutic target
    • Legoffic A, Calvo E, Cano C et al. The reg4 gene, amplified in the early stages of pancreatic cancer development, is a promising therapeutic target. PLoS ONE 2009; 4: e7495.
    • (2009) PLoS ONE , vol.4
    • Legoffic, A.1    Calvo, E.2    Cano, C.3
  • 24
    • 57049118967 scopus 로고    scopus 로고
    • Reg IV expression is associated with cell growth and prognosis of adenoid cystic carcinoma in the salivary gland
    • Sasahira T, Oue N, Kirita T et al. Reg IV expression is associated with cell growth and prognosis of adenoid cystic carcinoma in the salivary gland. Histopathology 2008; 53: 667-75.
    • (2008) Histopathology , vol.53 , pp. 667-675
    • Sasahira, T.1    Oue, N.2    Kirita, T.3
  • 26
    • 0036266409 scopus 로고    scopus 로고
    • Matrix metalloproteinase-7 is expressed by pancreatic cancer precursors and regulates acinar-to-ductal metaplasia in exocrine pancreas
    • Crawford HC, Scoggins CR, Washington MK, Matrisian LM, Leach SD. Matrix metalloproteinase-7 is expressed by pancreatic cancer precursors and regulates acinar-to-ductal metaplasia in exocrine pancreas. J Clin Invest 2002; 109: 1437-44.
    • (2002) J Clin Invest , vol.109 , pp. 1437-1444
    • Crawford, H.C.1    Scoggins, C.R.2    Washington, M.K.3    Matrisian, L.M.4    Leach, S.D.5
  • 27
    • 18544413108 scopus 로고    scopus 로고
    • Association of matrilysin expression with progression and poor prognosis in human pancreatic adenocarcinoma
    • Nakamura H, Horita S, Senmaru N et al. Association of matrilysin expression with progression and poor prognosis in human pancreatic adenocarcinoma. Oncol Rep 2002; 9: 751-5.
    • (2002) Oncol Rep , vol.9 , pp. 751-755
    • Nakamura, H.1    Horita, S.2    Senmaru, N.3
  • 28
    • 0035865438 scopus 로고    scopus 로고
    • Expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in human pancreatic adenocarcinomas: clinicopathologic and prognostic significance of matrilysin expression
    • Yamamoto H, Itoh F, Iku S et al. Expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in human pancreatic adenocarcinomas: clinicopathologic and prognostic significance of matrilysin expression. J Clin Oncol 2001; 19: 1118-27.
    • (2001) J Clin Oncol , vol.19 , pp. 1118-1127
    • Yamamoto, H.1    Itoh, F.2    Iku, S.3
  • 29
    • 21444444445 scopus 로고    scopus 로고
    • Involvement of matrix metalloproteinase-7 in invasion-metastasis through induction of cell dissociation in pancreatic cancer
    • Tan X, Egami H, Ishikawa S et al. Involvement of matrix metalloproteinase-7 in invasion-metastasis through induction of cell dissociation in pancreatic cancer. Int J Oncol 2005; 26: 1283-9.
    • (2005) Int J Oncol , vol.26 , pp. 1283-1289
    • Tan, X.1    Egami, H.2    Ishikawa, S.3
  • 30
    • 0036267895 scopus 로고    scopus 로고
    • Comparison of matrix metalloproteinase expression between primary tumors with or without liver metastasis in pancreatic and colorectal carcinomas
    • Matsuyama Y, Takao S, Aikou T. Comparison of matrix metalloproteinase expression between primary tumors with or without liver metastasis in pancreatic and colorectal carcinomas. J Surg Oncol 2002; 80: 105-10.
    • (2002) J Surg Oncol , vol.80 , pp. 105-110
    • Matsuyama, Y.1    Takao, S.2    Aikou, T.3
  • 31
    • 0036177290 scopus 로고    scopus 로고
    • Histologic features of venous invasion, expression of vascular endothelial growth factor and matrix metalloproteinase-2 and matrix metalloproteinase-9, and the relation with liver metastasis in pancreatic cancer
    • Nagakawa Y, Aoki T, Kasuya K, Tsuchida A, Koyanagi Y. Histologic features of venous invasion, expression of vascular endothelial growth factor and matrix metalloproteinase-2 and matrix metalloproteinase-9, and the relation with liver metastasis in pancreatic cancer. Pancreas 2002; 24: 169-78.
    • (2002) Pancreas , vol.24 , pp. 169-178
    • Nagakawa, Y.1    Aoki, T.2    Kasuya, K.3    Tsuchida, A.4    Koyanagi, Y.5
  • 32
    • 30044442435 scopus 로고    scopus 로고
    • Reg IV activates the epidermal growth factor receptor/Akt/AP-1 signaling pathway in colon adenocarcinomas
    • Bishnupuri KS, Luo Q, Murmu N, Houchen CW, Anant S, Dieckgraefe BK. Reg IV activates the epidermal growth factor receptor/Akt/AP-1 signaling pathway in colon adenocarcinomas. Gastroenterology 2006; 130: 137-49.
    • (2006) Gastroenterology , vol.130 , pp. 137-149
    • Bishnupuri, K.S.1    Luo, Q.2    Murmu, N.3    Houchen, C.W.4    Anant, S.5    Dieckgraefe, B.K.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.