Fibroblast growth factor 10 is critical for liver growth during embryogenesis and controls hepatoblast survival via β-catenin activation

Hepatology

Volumn 46, Issue 4, 2007, Pages 1187-1197

  Berg, Tove ^a   Rountree, C Bart ^a   Lee, Lily ^a   Estrada, Joaquin ^a   Sala, Frédéric G ^a   Choe, Andrea ^a   Veltmaat, Jacqueline M ^a,c   De Langhe, Stijn ^a   Lee, Rene ^a   Tsukamoto, Hide ^b   Crooks, Gay M ^a   Bellusci, Saverio ^a   Wang, Kasper S ^a,b,d  

^a CHILDREN S HOSPITAL LOS ANGELES   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^c INSTITUTE OF MOLECULAR AND CELL BIOLOGY   (Singapore)

^d UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; BETA GALACTOSIDASE; FIBROBLAST GROWTH FACTOR 10; FIBROBLAST GROWTH FACTOR RECEPTOR 2; FIBROBLAST GROWTH FACTOR RECEPTOR 2B; MATRIGEL; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; CYTOMETRY; EMBRYO; EMBRYO DEVELOPMENT; ENZYME ACTIVITY; GENE EXPRESSION; LIVER DEVELOPMENT; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ANIMALS; BETA CATENIN; BETA-GALACTOSIDASE; CELL PROLIFERATION; CELL SURVIVAL; CELLS, CULTURED; EMBRYONIC DEVELOPMENT; FIBROBLAST GROWTH FACTOR 10; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HEPATOCYTES; LIVER; MICE; MICE, INBRED C57BL; MICE, MUTANT STRAINS; RECEPTOR, FIBROBLAST GROWTH FACTOR, TYPE 2; SIGNAL TRANSDUCTION;

EID: 35348863841     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1002/hep.21814     Document Type: Article

References (28)

1. Zaret KS. Hepatocyte differentiation: from the endoderm and beyond. Curr Opin Genet Dev 2001;11:568-574.
2. Walkup MH, Gerber DA. Hepatic stem cells: in search of. Stem Cells 2006;24:1833-1840.
3. Kolterud A, Wandzioch E, Carlsson L. Lhx2 is expressed in the septum transversum mesenchyme that becomes an integral part of the liver and the formation of these cells is independent of functional Lhx2. Gene Expr Patterns 2004;4:521-528.
4. Miura K, Nagai H, Ueno Y, Goto T, Mikami K, Nakane K, et al. Epimorphin is involved in differentiation of rat hepatic stem-like cells through cell-cell contact. Biochem Biophys Res Commun 2003;311:415-423.
5. Asahina K, Sato H, Yamasaki C, Kataoka M, Shiokawa M, Katayama S, et al. Pleiotrophin/heparin-binding growth-associated molecule as a mitogen of rat hepatocytes and its role in regeneration and development of liver. Am J Pathol 2002;160:2191-2205.
6. Jung J, Zheng M, Goldfarb M, Zaret KS. Initiation of mammalian liver development from endoderm by fibroblast growth factors. Science 1999;284:1998-2003.
7. Sala FG, Curtis JL, Veltmaat JM, Del Moral PM, Le LT, Fairbanks TJ, et al. Fibroblast growth factor 10 is required for survival and proliferation but not differentiation of intestinal epithelial progenitor cells during murine colon development. Dev Biol 2006;299:373-385.
8. Nyeng P, Norgaard GA, Kobberup S, Jensen J. FGF10 signaling controls stomach morphogenesis. Dev Biol 2007;303:295-310.
9. Norgaard GA, Jensen JN, Jensen J. FGF10 signaling maintains the pancreatic progenitor cell state revealing a novel role of Notch in organ development. Dev Biol 2003;264:323-338.
10. Itoh N, Ornitz DM. Evolution of the Fgf and Fgfr gene families. Trends Genet 2004;20:563-569.
11. Sekine K, Ohuchi H, Fujiwara M, Yamasaki M, Yoshizawa T, Sato T, et al. Fgf10 is essential for limb and lung formation. Nat Genet 1999;21:138-141.
12. Steiling H, Wustefeld T, Bugnon P, Brauchle M, Fassler R, Teupser D, et al. Fibroblast growth factor receptor signalling is crucial for liver homeostasis and regeneration. Oncogene 2003;22:4380-4388.
13. Mimeault M, Batra SK. Concise review: recent advances on the significance of stem cells in tissue regeneration and cancer therapies. Stem Cells 2006;24:2319-2345.
14. Monga SP, Mars WM, Pediaditakis P, Bell A, Mule K, Bowen WC, et al. Hepatocyte growth factor induces Wnt-independent nuclear translocation of beta-catenin after Met-beta-catenin dissociation in hepatocytes. Cancer Res 2002;62:2064-2071.
15. Nusse R. WNT targets. Repression and activation. Trends Genet 1999;15:1-3.
16. Mailleux AA, Spencer-Dene B, Dillon C, Ndiaye D, Savona-Baron C, Itoh N, et al. Role of FGF10/FGFR2b signaling during mammary gland development in the mouse embryo. Development 2002;129:53-60.
17. DasGupta R, Fuchs E. Multiple roles for activated LEF/TCF transcription complexes during hair follicle development and differentiation. Development 1999;126:4557-4568.
18. Kelly RG, Brown NA, Buckingham ME. The arterial pole of the mouse heart forms from Fgf10-expressing cells in pharyngeal mesoderm. Dev Cell 2001;1:435-440.
19. Rountree CB, Wang X, Ge S, Barsky L, Zhu J, Gonzales I, et al. Bone marrow fails to differentiate into liver epithelium during murine development and regeneration. HEPATOLOGY 2007;45:1250-1260.
20. Knittel T, Kobold D, Saile B, Grundmann A, Neubauer K, Piscaglia F, et al. Rat liver myofibroblasrs and hepatic stellate cells: different cell populations of the fibroblast lineage with fibrogenic potential. Gastroenterology 1999;117:1205-1221.
21. De ML, Spencer-Dene B, Revest J, Hajihosseini M, Rosewell I, Dickson C. An important role for the IIIb isoform of fibroblast growth factor receptor 2 (FGFR2) in mesenchymal-epithelial signalling during mouse organogenesis. Development 2000;127:483-492.
22. Veltmaat JM, Relaix F, Le LT, Krarochwil K, Sala FG, van VW, et al. Gli3-mediated somitic Fgf10 expression gradients are required for the induction and patterning of mammary epithelium along the embryonic axes. Development 2006;133:2325-2335.
23. Micsenyi A, Tan X, Sneddon T, Luo JH, Michalopoulos GK, Monga SP. Beta-catenin is temporally regulated during normal liver development. Gastroenterology 2004;126:1134-1146.
24. Sekhon SS, Tan X, Micsenyi A, Bowen WC, Monga SP. Fibroblast growth factor enriches the embryonic liver cultures for hepatic progenitors. Am J Pathol 2004;164:2229-2240.
25. Suksaweang S, Lin CM, Jiang TX, Hughes MW, Widelitz RB, Chuong CM. Morphogenesis of chicken liver: identification of localized growth zones and the role of beta-catenin/Wnt in size regulation. Dev Biol 2004;266:109-122.
26. Reddy S, Andl T, Bagasra A, Lu MM, Epstein DJ, Morrisey EE, et al. Characterization of Wnt gene expression in developing and postnatal hair follicles and identification of Wnt5a as a target of Sonic hedgehog in hair follicle morphogenesis. Mech Dev 2001;107:69-82.
27. He XC, Yin T, Grindley JC, Tian Q, Saro T, Tao WA, et al. PTEN-deficient intestinal stem cells initiate intestinal polyposis. Nat Genet 2007;39:189-198.
28. Jiang F, Parsons CJ, Stefanovic B. Gene expression profile of quiescent and activated tat hepatic stellate cells implicates Wnt signaling pathway in activation. J Hepatol 2006;45:401-409.