Homocysteine-induced cardiomyocyte apoptosis and plasma membrane flip-flop are independent of S-adenosylhomocysteine: A crucial role for nuclear p47 phox

Molecular and Cellular Biochemistry

Volumn 358, Issue 1-2, 2011, Pages 229-239

  Sipkens, Jessica A ^a   Krijnen, Paul A J ^a   Hahn, Nynke E ^a   Wassink, Melissa ^a   Meischl, Christof ^a   Smith, Desirée E C ^a   Musters, René J P ^a   Stehouwer, Coen D A ^b   Rauwerda, Jan A ^a   Van Hinsbergh, Victor W M ^a   Niessen, Hans W M ^a  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^b MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Cardiomyocyte apoptosis; Homocysteine; Membrane flip flop; S adenosylhomocysteine

Indexed keywords

3 NITROTYROSINE; 3-NITROTYROSINE; ADENOSINE; ADENOSINE TRIPHOSPHATE; CASPASE 3; CYBB PROTEIN, RAT; DRUG DERIVATIVE; HOMOCYSTEINE; MEMBRANE PROTEIN; NEUTROPHIL CYTOSOLIC FACTOR 1; PERIODATE OXIDIZED ADENOSINE; PERIODATE-OXIDIZED ADENOSINE; PHOSPHOLIPID TRANSFER PROTEIN; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; S ADENOSYLHOMOCYSTEINE; S ADENOSYLMETHIONINE; TYROSINE;

ANIMAL; APOPTOSIS; ARTICLE; CELL MEMBRANE; CELL NUCLEUS; CELL SURVIVAL; CYTOLOGY; DRUG EFFECT; ENZYMOLOGY; EXTRACELLULAR SPACE; HEART MUSCLE CELL; INTRACELLULAR SPACE; METABOLISM; RAT;

ADENOSINE; ADENOSINE TRIPHOSPHATE; ANIMALS; APOPTOSIS; CASPASE 3; CELL MEMBRANE; CELL NUCLEUS; CELL SURVIVAL; EXTRACELLULAR SPACE; HOMOCYSTEINE; INTRACELLULAR SPACE; MEMBRANE GLYCOPROTEINS; MYOCYTES, CARDIAC; NADPH OXIDASE; PHOSPHOLIPID TRANSFER PROTEINS; RATS; REACTIVE OXYGEN SPECIES; S-ADENOSYLHOMOCYSTEINE; S-ADENOSYLMETHIONINE; TYROSINE;

EID: 84870569166     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-011-0973-4     Document Type: Article

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