Cholesterol and breast cancer development

Current Opinion in Pharmacology

Volumn 12, Issue 6, 2012, Pages 677-682

  Danilo, Christiane ^a   Frank, Philippe G ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL; EZETIMIBE; HIGH DENSITY LIPOPROTEIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL;

ARTICLE; BREAST CANCER; CANCER CELL; CANCER RISK; CELL PROLIFERATION; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL INTAKE; CHOLESTEROL METABOLISM; DIABETES MELLITUS; HUMAN; METASTASIS; NONHUMAN; PRIORITY JOURNAL; PROSTATE CANCER; PROSTATE TUMOR; RISK ASSESSMENT; RISK FACTOR;

EID: 84870563295     PISSN: 14714892     EISSN: 14714973     Source Type: Journal    
DOI: 10.1016/j.coph.2012.07.009     Document Type: Review

References (58)

1. R. Siegel, D. Naishadham, and A. Jemal Cancer statistics, 2012 CA Cancer J Clin 62 2012 10 29
2. A. Jemal, F. Bray, M.M. Center, J. Ferlay, E. Ward, and D. Forman Global cancer statistics CA Cancer J Clin 61 2011 69 90
3. K. McPherson, C.M. Steel, and J.M. Dixon ABC of breast diseases. Breast cancer-epidemiology, risk factors, and genetics BMJ 321 2000 624 628
4. M. Lof, and E. Weiderpass Impact of diet on breast cancer risk Curr Opin Obstet Gynecol 21 2009 80 85
5. D.C. McMillan, N. Sattar, and C.S. McArdle ABC of obesity. Obesity and cancer BMJ 333 2006 1109 1111
6. Y. Kim, S.K. Park, W. Han, D.H. Kim, Y.C. Hong, E.H. Ha, S.H. Ahn, D.Y. Noh, D. Kang, and K.Y. Yoo Serum high-density lipoprotein cholesterol and breast cancer risk by menopausal status, body mass index, and hormonal receptor in Korea Cancer Epidemiol Biomarkers Prev 18 2009 508 515
7. A.S. Furberg, M.B. Veierod, T. Wilsgaard, L. Bernstein, and I. Thune Serum high-density lipoprotein cholesterol, metabolic profile, and breast cancer risk J Natl Cancer Inst 96 2004 1152 1160
8. N. Potischman, C.E. McCulloch, T. Byers, L. Houghton, T. Nemoto, S. Graham, and T.C. Campbell Associations between breast cancer, plasma triglycerides, and cholesterol Nutr Cancer 15 1991 205 215
9. G. Ray, and S.A. Husain Role of lipids, lipoproteins and vitamins in women with breast cancer Clin Biochem 34 2001 71 76
10. S.B. Kritchevsky, and D. Kritchevsky Serum cholesterol and cancer risk: an epidemiologic perspective Annu Rev Nutr 12 1992 391 416
11. N.F. Boyd, and V. McGuire Evidence of association between plasma high-density lipoprotein cholesterol and risk factors for breast cancer J Natl Cancer Inst 82 1990 460 468
12. M. Ferraroni, M. Gerber, A. Decarli, S. Richardson, E. Marubini, P. Crastes de Paulet, A. Crastes de Paulet, and H. Pujol HDL-cholesterol and breast cancer: a joint study in northern Italy and southern France Int J Epidemiol 22 1993 772 780
13. S.S. Martin, R.S. Blumenthal, and M. Miller LDL cholesterol: the lower the better Med Clin North Am 96 2012 13 26
14. M. Gaard, S. Tretli, and P. Urdal Risk of breast cancer in relation to blood lipids: a prospective study of 31,209 Norwegian women Cancer Causes Control 5 1994 501 509
15. E.A. Mady Association between estradiol, estrogen receptors, total lipids, triglycerides, and cholesterol in patients with benign and malignant breast tumors J Steroid Biochem Mol Biol 75 2000 323 328
16. P.G. Moorman, B.S. Hulka, R.A. Hiatt, N. Krieger, B. Newman, J.H. Vogelman, and N. Orentreich Association between high-density lipoprotein cholesterol and breast cancer varies by menopausal status Cancer Epidemiol Biomarkers Prev 7 1998 483 488
17. L.J. Vatten, and O.P. Foss Total serum cholesterol and triglycerides and risk of breast cancer: a prospective study of 24,329 Norwegian women Cancer Res 50 1990 2341 2346
18. M. Ha, J. Sung, and Y.M. Song Serum total cholesterol and the risk of breast cancer in postmenopausal Korean women Cancer Causes Control 20 2009 1055 1060
19. T. Bjorge, A. Lukanova, H. Jonsson, S. Tretli, H. Ulmer, J. Manjer, T. Stocks, R. Selmer, G. Nagel, and M. Almquist Metabolic syndrome and breast cancer in the me-can (metabolic syndrome and cancer) project Cancer Epidemiol Biomarkers Prev 19 2010 1737 1745
20. G.C. Kabat, M. Kim, R.T. Chlebowski, J. Khandekar, M.G. Ko, A. McTiernan, M.L. Neuhouser, D.R. Parker, J.M. Shikany, and M.L. Stefanick A longitudinal study of the metabolic syndrome and risk of postmenopausal breast cancer Cancer Epidemiol Biomarkers Prev 18 2009 2046 2053
21. V. Rosato, C. Bosetti, R. Talamini, F. Levi, M. Montella, A. Giacosa, E. Negri, and C. La Vecchia Metabolic syndrome and the risk of breast cancer in postmenopausal women Ann Oncol 22 2011 2687 2692
22. A.M. Kucharska-Newton, W.D. Rosamond, P.J. Mink, A.J. Alberg, E. Shahar, and A.R. Folsom HDL-cholesterol and incidence of breast cancer in the ARIC cohort study Ann Epidemiol 18 2008 671 677
23. C.M. Kitahara, A. Berrington de Gonzalez, N.D. Freedman, R. Huxley, Y. Mok, S.H. Jee, and J.M. Samet Total cholesterol and cancer risk in a large prospective study in Korea J Clin Oncol 29 2011 1592 1598
24. J. Hu, C. La Vecchia, M. de Groh, E. Negri, H. Morrison, and L. Mery Dietary cholesterol intake and cancer Ann Oncol 23 2011 491 500
25. A.L. Ronco, E. De Stefani, and M. Stoll Hormonal and metabolic modulation through nutrition: towards a primary prevention of breast cancer Breast 19 2010 322 332
26. M. Rotheneder, and G.M. Kostner Effects of low- and high-density lipoproteins on the proliferation of human breast cancer cells in vitro: differences between hormone-dependent and hormone-independent cell lines Int J Cancer 43 1989 875 879
27. D. Gospodarowicz, G.M. Lui, and R. Gonzalez High-density lipoproteins and the proliferation of human tumor cells maintained on extracellular matrix-coated dishes and exposed to defined medium Cancer Res 42 1982 3704 3713
28. P.J. Pussinen, B. Karten, A. Wintersperger, H. Reicher, M. McLean, E. Malle, and W. Sattler The human breast carcinoma cell line HBL-100 acquires exogenous cholesterol from high-density lipoprotein via CLA-1 (CD-36 and LIMPII analogous 1)-mediated selective cholesteryl ester uptake Biochem J 349 2000 559 566
29. C.J. Antalis, T. Arnold, T. Rasool, B. Lee, K.K. Buhman, and R.A. Siddiqui High ACAT1 expression in estrogen receptor negative basal-like breast cancer cells is associated with LDL-induced proliferation Breast Cancer Res Treat 122 2010 661 670
30. G.J. Warner, G. Stoudt, M. Bamberger, W.J. Johnson, and G.H. Rothblat Cell toxicity induced by inhibition of acyl coenzyme A:cholesterol acyltransferase and accumulation of unesterified cholesterol J Biol Chem 270 1995 5772 5778
31. C.J. Antalis, A. Uchida, K.K. Buhman, and R.A. Siddiqui Migration of MDA-MB-231 breast cancer cells depends on the availability of exogenous lipids and cholesterol esterification Clin Exp Metastasis 28 2010 733 741
32. M.R. Paillasse, P. de Medina, G. Amouroux, L. Mhamdi, M. Poirot, and S. Silvente-Poirot Signaling through cholesterol esterification: a new pathway for the cholecystokinin 2 receptor involved in cell growth and invasion J Lipid Res 50 2009 2203 2211
33. P. de Medina, S. Genovese, M.R. Paillasse, M. Mazaheri, S. Caze-Subra, K. Bystricky, M. Curini, S. Silvente-Poirot, F. Epifano, and M. Poirot Auraptene is an inhibitor of cholesterol esterification and a modulator of estrogen receptors Mol Pharmacol 78 2010 827 836
34. D.P. Edwards Regulation of signal transduction pathways by estrogen and progesterone Annu Rev Physiol 67 2005 335 376
35. B. Lindenthal, A.L. Holleran, T.A. Aldaghlas, B. Ruan, G.J. Schroepfer Jr., W.K. Wilson, and J.K. Kelleher Progestins block cholesterol synthesis to produce meiosis-activating sterols FASEB J 15 2001 775 784
36. R.C. Sexton, S.R. Panini, F. Azran, and H. Rudney Effects of 3 beta-[2-(diethylamino)ethoxy]androst-5-en-17-one on the synthesis of cholesterol and ubiquinone in rat intestinal epithelial cell cultures Biochemistry 22 1983 5687 5692
37. M.C. Battista, M.O. Guimond, C. Roberge, A.A. Doueik, L. Fazli, M. Gleave, R. Sabbagh, and N. Gallo-Payet Inhibition of DHCR24/seladin-1 impairs cellular homeostasis in prostate cancer Prostate 70 2010 921 933
38. F.F. Moebius, R.J. Reiter, K. Bermoser, H. Glossmann, S.Y. Cho, and Y.K. Paik Pharmacological analysis of sterol delta8-delta7 isomerase proteins with [3H]ifenprodil Mol Pharmacol 54 1998 591 598
39. P. de Medina, M.R. Paillasse, G. Segala, M. Poirot, and S. Silvente-Poirot Identification and pharmacological characterization of cholesterol-5,6-epoxide hydrolase as a target for tamoxifen and AEBS ligands Proc Natl Acad Sci USA 107 2010 13520 13525
40. B. Pan, H. Ren, X. Lv, Y. Zhao, B. Yu, Y. He, Y. Ma, C. Niu, J. Kong, and F. Yu Hypochlorite-induced oxidative stress elevates the capability of HDL in promoting breast cancer metastasis J Transl Med 10 2012 65
41. B. Pan, H. Ren, Y. Ma, D. Liu, B. Yu, L. Ji, L. Pan, J. Li, L. Yang, and X. Lv High-density lipoprotein of patients with type 2 diabetes mellitus elevates the capability of promoting migration and invasion of breast cancer cells Int J Cancer 131 2011 70 82
42. B. Pan, H. Ren, Y. He, X. Lv, Y. Ma, J. Li, L. Huang, B. Yu, J. Kong, and C. Niu HDL of patients with type 2 diabetes mellitus elevates the capability of promoting breast cancer metastasis Clin Cancer Res 18 2012 1246 1256
43. W.M. Cao, K. Murao, H. Imachi, X. Yu, H. Abe, A. Yamauchi, M. Niimi, A. Miyauchi, N.C. Wong, and T. Ishida A mutant high-density lipoprotein receptor inhibits proliferation of human breast cancer cells Cancer Res 64 2004 1515 1521
44. G. Llaverias, C. Danilo, I. Mercier, K. Daumer, F. Capozza, T.M. Williams, F. Sotgia, M.P. Lisanti, and P.G. Frank Role of cholesterol in the development and progression of breast cancer Am J Pathol 178 2011 402 412
45. Alikhani N, Ferguson RD, Novosyadlyy R, Gallagher EJ, Scheinman EJ, Yakar S, Leroith D: Mammary tumor growth and pulmonary metastasis are enhanced in a hyperlipidemic mouse model. Oncogene 2012, in press, http://dx.doi.org/10.1038/ onc.2012.113.
46. L. Zhuang, J. Kim, R.M. Adam, K.R. Solomon, and M.R. Freeman Cholesterol targeting alters lipid raft composition and cell survival in prostate cancer cells and xenografts J Clin Invest 115 2005 959 968
47. K.R. Solomon, K. Pelton, K. Boucher, J. Joo, C. Tully, D. Zurakowski, C.P. Schaffner, J. Kim, and M.R. Freeman Ezetimibe is an inhibitor of tumor angiogenesis Am J Pathol 174 2009 1017 1026
48. G. Llaverias, C. Danilo, Y. Wang, A.K. Witkiewicz, K. Daumer, M.P. Lisanti, and P.G. Frank A Western-type diet accelerates tumor progression in an autochthonous mouse model of prostate cancer Am J Pathol 177 2010 3180 3191
49. Y. Sekine, S.J. Demosky, J.A. Stonik, Y. Furuya, H. Koike, K. Suzuki, and A.T. Remaley High-density lipoprotein induces proliferation and migration of human prostate androgen-independent cancer cells by an ABCA1-dependent mechanism Mol Cancer Res 8 2010 1284 1294
50. Y. Sekine, K. Suzuki, and A.T. Remaley HDL and sphingosine-1-phosphate activate stat3 in prostate cancer DU145 cells via ERK1/2 and S1P receptors, and promote cell migration and invasion Prostate 71 2011 690 699
51. N. Bulat, G. Waeber, and C. Widmann LDLs stimulate p38 MAPKs and wound healing through SR-BI independently of Ras and PI3 kinase J Lipid Res 50 2009 81 89
52. T. Grewal, I. de Diego, M.F. Kirchhoff, F. Tebar, J. Heeren, F. Rinninger, and C. Enrich High density lipoprotein-induced signaling of the MAPK pathway involves scavenger receptor type BI-mediated activation of Ras J Biol Chem 278 2003 16478 16481
53. C. Mineo, I.S. Yuhanna, M.J. Quon, and P.W. Shaul High density lipoprotein-induced endothelial nitric-oxide synthase activation is mediated by Akt and MAP kinases J Biol Chem 278 2003 9142 9149
54. D. Seetharam, C. Mineo, A.K. Gormley, L.L. Gibson, W. Vongpatanasin, K.L. Chambliss, L.D. Hahner, M.L. Cummings, R.L. Kitchens, and Y.L. Marcel High-density lipoprotein promotes endothelial cell migration and reendothelialization via scavenger receptor-B type I Circ Res 98 2006 63 72
55. K.S. George, and S. Wu Lipid raft: a floating island of death or survival Toxicol Appl Pharmacol 259 2012 311 319
56. T. Murai The role of lipid rafts in cancer cell adhesion and migration Int J Cell Biol 2012 2011 763283
57. K. Simons, and D. Toomre Lipid rafts and signal transduction Nat Rev Mol Cell Biol 1 2000 31 39
58. J.D. Yager, and N.E. Davidson Estrogen carcinogenesis in breast cancer N Engl J Med 354 2006 270 282