-
1
-
-
0030858044
-
Cholesterol biosynthesis from lanosterol: Development of a novel assay method and characterization of rat liver microsomal lanosterol Δ24-reductase
-
Bae S-H and Paik Y-K (1997) Cholesterol biosynthesis from lanosterol: development of a novel assay method and characterization of rat liver microsomal lanosterol Δ24-reductase. Biochem J 326:609-616.
-
(1997)
Biochem J
, vol.326
, pp. 609-616
-
-
Bae, S.-H.1
Paik, Y.-K.2
-
3
-
-
0017184389
-
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
-
Bradford MM (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254.
-
(1976)
Anal Biochem
, vol.72
, pp. 248-254
-
-
Bradford, M.M.1
-
4
-
-
3543097750
-
Butyrophenones as inhibitors of cholesterol biosynthesis
-
Braun GA (1969) Butyrophenones as inhibitors of cholesterol biosynthesis. Adv Exp Med Biol 4:473-482.
-
(1969)
Adv Exp Med Biol
, vol.4
, pp. 473-482
-
-
Braun, G.A.1
-
5
-
-
0030970833
-
L-type calcium channels: Binding domains for dihydropyridines and benzothiazepines are located in close proximity to each other
-
Brauns T, Prinz H, Kimball SD, Haugland RP, Striessnig J, and Glossmann H (1997) L-type calcium channels: binding domains for dihydropyridines and benzothiazepines are located in close proximity to each other. Biochemistry 36:3625-3631.
-
(1997)
Biochemistry
, vol.36
, pp. 3625-3631
-
-
Brauns, T.1
Prinz, H.2
Kimball, S.D.3
Haugland, R.P.4
Striessnig, J.5
Glossmann, H.6
-
6
-
-
0026721018
-
Spiropiperidines as high-affinity, selective sigma ligands
-
Chambers MS, Baker R, Billington DC, Knight AK, Middlemiss DN, and Wong EHF (1992) Spiropiperidines as high-affinity, selective sigma ligands. J Med Chem 35:2033-2039.
-
(1992)
J Med Chem
, vol.35
, pp. 2033-2039
-
-
Chambers, M.S.1
Baker, R.2
Billington, D.C.3
Knight, A.K.4
Middlemiss, D.N.5
Wong, E.H.F.6
-
7
-
-
0023239318
-
Triphenylethylene antiestrogen binding sites (TABS) specificity
-
Clark JH, Mitchell WC, and Guthrie SC (1987) Triphenylethylene antiestrogen binding sites (TABS) specificity. J Steroid Biochem 26:433-437.
-
(1987)
J Steroid Biochem
, vol.26
, pp. 433-437
-
-
Clark, J.H.1
Mitchell, W.C.2
Guthrie, S.C.3
-
8
-
-
0031895371
-
Disorders of cholesterol biosynthesis
-
Clayton PT (1998) Disorders of cholesterol biosynthesis. Arch Dis Child 73:185-189.
-
(1998)
Arch Dis Child
, vol.73
, pp. 185-189
-
-
Clayton, P.T.1
-
9
-
-
0018001339
-
Simultaneous analysis of families of sigmoid curves: Application to bioassays, radioligand assay and physiological dose-response curves
-
DeLean A, Munson PJ, and Rodbard D (1978) Simultaneous analysis of families of sigmoid curves: application to bioassays, radioligand assay and physiological dose-response curves. Am J Physiol 4:E97-E102.
-
(1978)
Am J Physiol
, vol.4
-
-
DeLean, A.1
Munson, P.J.2
Rodbard, D.3
-
10
-
-
0023257528
-
Calmodulin antagonists suppress cholesterol biosynthesis by inhibiting sterol Δ24 reductase
-
Filipovic I and Buddecke E (1987) Calmodulin antagonists suppress cholesterol biosynthesis by inhibiting sterol Δ24 reductase. Lipids 22:261-265.
-
(1987)
Lipids
, vol.22
, pp. 261-265
-
-
Filipovic, I.1
Buddecke, E.2
-
11
-
-
0032493196
-
Mutations in the Δ7-sterol reductase gene in patients with the Smith-Lemli-Opitz syndrome
-
Fitzky BU, Witsch-Baumgartner M, Erdel M, Lee JN, Paik YK, Glossmann H, Utermann G, and Moebius FA (1998) Mutations in the Δ7-sterol reductase gene in patients with the Smith-Lemli-Opitz syndrome. Proc Natl Acad Sci USA 95:8181-8186.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 8181-8186
-
-
Fitzky, B.U.1
Witsch-Baumgartner, M.2
Erdel, M.3
Lee, J.N.4
Paik, Y.K.5
Glossmann, H.6
Utermann, G.7
Moebius, F.A.8
-
12
-
-
0029871365
-
Interactions between ifenprodil and the NR2B subunit of the N-methyl-D-aspartate receptor
-
Gallagher MJ, Huang H, Pritchett DB, and Lynch DR (1996) Interactions between ifenprodil and the NR2B subunit of the N-methyl-D-aspartate receptor. J Biol Chem 271:9603-9611.
-
(1996)
J Biol Chem
, vol.271
, pp. 9603-9611
-
-
Gallagher, M.J.1
Huang, H.2
Pritchett, D.B.3
Lynch, D.R.4
-
13
-
-
0028835120
-
Tamoxifen and toremifene lower serum cholesterol by inhibition of Δ8-cholestenol conversion to lathosterol in women with breast cancer
-
Gylling H, Pyrhönen S, Mäntylä E, Mäenpää H, Kangas L, and Miettinen TA. Tamoxifen and toremifene lower serum cholesterol by inhibition of Δ8-cholestenol conversion to lathosterol in women with breast cancer. J Clin Oncol 13:2900-2905, (1995).
-
(1995)
J Clin Oncol
, vol.13
, pp. 2900-2905
-
-
Gylling, H.1
Pyrhönen, S.2
Mäntylä, E.3
Mäenpää, H.4
Kangas, L.5
Miettinen, T.A.6
-
14
-
-
0028987135
-
2+ antagonist binding protein: Molecular cloning, tissue distribution, and heterologous expression
-
2+ antagonist binding protein: molecular cloning, tissue distribution, and heterologous expression. J Biol Chem 270:7551-7557.
-
(1995)
J Biol Chem
, vol.270
, pp. 7551-7557
-
-
Hanner, M.1
Moebius, F.F.2
Weber, F.3
Grabner, M.4
Striessnig, J.5
Glossmann, H.6
-
16
-
-
0027335978
-
3H]ifenprodil binding to sigma receptors in rat brain
-
3H]ifenprodil binding to sigma receptors in rat brain. Eur J Pharmacol 236:159-163.
-
(1993)
Eur J Pharmacol
, vol.236
, pp. 159-163
-
-
Hashimoto, K.1
London, E.D.2
-
17
-
-
0025098896
-
High-affinity binding sites for oxygenated sterols in rat liver microsomes: Possible identity with antiestrogen binding sites
-
Hwang PLH (1990) High-affinity binding sites for oxygenated sterols in rat liver microsomes: possible identity with antiestrogen binding sites. Biochem Biophys Acta 1033:154-161.
-
(1990)
Biochem Biophys Acta
, vol.1033
, pp. 154-161
-
-
Hwang, P.L.H.1
-
18
-
-
0028920880
-
Cholesterol biosynthesis from lanosterol: Regulation and purification of rat hepatic sterol 8-isomerase
-
Kang M, Kim C, Johng T, and Paik Y (1995) Cholesterol biosynthesis from lanosterol: regulation and purification of rat hepatic sterol 8-isomerase. J Biochem 117:819-823.
-
(1995)
J Biochem
, vol.117
, pp. 819-823
-
-
Kang, M.1
Kim, C.2
Johng, T.3
Paik, Y.4
-
19
-
-
0029945013
-
An aspartate residue in the extracellular loop of the N-methyl-D-aspartate receptor controls sensitivity to spermine and protons
-
Kasiwagi K, Fukuchi J, Igarashi K, and Williams K (1996) An aspartate residue in the extracellular loop of the N-methyl-D-aspartate receptor controls sensitivity to spermine and protons. Mol Pharmacol 49:1131-1141.
-
(1996)
Mol Pharmacol
, vol.49
, pp. 1131-1141
-
-
Kasiwagi, K.1
Fukuchi, J.2
Igarashi, K.3
Williams, K.4
-
20
-
-
2642695321
-
Inhibition of the conversion of 7-dehydrocholesterol to cholesterol by AY-9944
-
Kraml M, Bagli JF, and Dvornik D (1964) Inhibition of the conversion of 7-dehydrocholesterol to cholesterol by AY-9944. Biochem Biophys Res Commun 15:455-457.
-
(1964)
Biochem Biophys Res Commun
, vol.15
, pp. 455-457
-
-
Kraml, M.1
Bagli, J.F.2
Dvornik, D.3
-
21
-
-
0029100192
-
Enzyme inhibition during the conversion of squalene to cholesterol
-
Lewis D, Galczenski H, Needle S, Tang S-Y, Amin D, Gleason M, Bilder G, Perrone M, Merkel L, and Rojas C (1995) Enzyme inhibition during the conversion of squalene to cholesterol. Steroids 60:475-483.
-
(1995)
Steroids
, vol.60
, pp. 475-483
-
-
Lewis, D.1
Galczenski, H.2
Needle, S.3
Tang, S.-Y.4
Amin, D.5
Gleason, M.6
Bilder, G.7
Perrone, M.8
Merkel, L.9
Rojas, C.10
-
22
-
-
0020446693
-
Calculating the dissociation constant of an unlabeled compound from the concentration required to displace radioactive binding by 50%
-
Linden J (1982) Calculating the dissociation constant of an unlabeled compound from the concentration required to displace radioactive binding by 50%. J Cycl Nucleotide Res 8:163-172.
-
(1982)
J Cycl Nucleotide Res
, vol.8
, pp. 163-172
-
-
Linden, J.1
-
23
-
-
0021280874
-
An embryotoxicity study of the fungicide tridemorph and its commercial formulation calixin
-
Merkle J, Schulz V, and Gelbke HP (1984) An embryotoxicity study of the fungicide tridemorph and its commercial formulation calixin. Teratology 29:259-269.
-
(1984)
Teratology
, vol.29
, pp. 259-269
-
-
Merkle, J.1
Schulz, V.2
Gelbke, H.P.3
-
24
-
-
0030022955
-
Role of multidrug resistance P-glycoprotein in cholesterol biosynthesis
-
Metherall JE and Huijan L (1996) Role of multidrug resistance P-glycoprotein in cholesterol biosynthesis. J Biol Chem 271:2634-2640.
-
(1996)
J Biol Chem
, vol.271
, pp. 2634-2640
-
-
Metherall, J.E.1
Huijan, L.2
-
26
-
-
0027463541
-
Biochemical characterization of a 22-kDa high affinity anti-ischemic drug-binding polypeptide in the endoplasmic reticulum of guinea pig liver: Potential common target for anti-ischemic drug action
-
Moebius FF, Burrows GG, Striessnig J, and Glossmann H (1993) Biochemical characterization of a 22-kDa high affinity anti-ischemic drug-binding polypeptide in the endoplasmic reticulum of guinea pig liver: potential common target for anti-ischemic drug action. Mol Pharmacol 43:139-148.
-
(1993)
Mol Pharmacol
, vol.43
, pp. 139-148
-
-
Moebius, F.F.1
Burrows, G.G.2
Striessnig, J.3
Glossmann, H.4
-
27
-
-
0032539605
-
Molecular cloning and expression of the human Δ7-sterol reductase
-
Moebius FF, Fitzky BU, Lee JN, Paik Y-K, and Glossmann H (1998) Molecular cloning and expression of the human Δ7-sterol reductase. Proc Natl Acad Sci USA 95:1899-1902.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 1899-1902
-
-
Moebius, F.F.1
Fitzky, B.U.2
Lee, J.N.3
Paik, Y.-K.4
Glossmann, H.5
-
29
-
-
0030949390
-
The mysteries of sigma receptors: New family members reveal a role in cholesterol synthesis
-
Moebius FF, Striessnig J, and Glossmann H (1997b) The mysteries of sigma receptors: new family members reveal a role in cholesterol synthesis. Trends Pharmacol Sci 18:67-70.
-
(1997)
Trends Pharmacol Sci
, vol.18
, pp. 67-70
-
-
Moebius, F.F.1
Striessnig, J.2
Glossmann, H.3
-
30
-
-
0023031854
-
Microsomal enzymes of cholesterol biosynthesis: Solubilization and purification of steroid 8-isomerase
-
Paik Y-K, Billheimer JT, Magolda RL, and Gaylor JL (1986) Microsomal enzymes of cholesterol biosynthesis: solubilization and purification of steroid 8-isomerase. J Biol Chem 261:6470-6477.
-
(1986)
J Biol Chem
, vol.261
, pp. 6470-6477
-
-
Paik, Y.-K.1
Billheimer, J.T.2
Magolda, R.L.3
Gaylor, J.L.4
-
31
-
-
0024512892
-
Inhibition of cholesterol synthesis and cell growth by 24(R,S),25-iminolanosterol and triparanol in cultured rat hepatoma cells
-
Popják G, Meenan A, Parish EJ, and Nes WD (1989) Inhibition of cholesterol synthesis and cell growth by 24(R,S),25-iminolanosterol and triparanol in cultured rat hepatoma cells. J Biol Chem 264:6230-6238.
-
(1989)
J Biol Chem
, vol.264
, pp. 6230-6238
-
-
Popják, G.1
Meenan, A.2
Parish, E.J.3
Nes, W.D.4
-
32
-
-
0028823737
-
Pharmacological properties of recombinant human N-methyl-D-aspartate receptors comprising NR1a/NR2A and NR1a/NR2B subunit assemblies expressed in permanently transfected mouse fibroblast cells
-
Priestley T, Laughton P, Myers J, Le Bourdelle B, Kerby J, and Whiting PJ (1995) Pharmacological properties of recombinant human N-methyl-D-aspartate receptors comprising NR1a/NR2A and NR1a/NR2B subunit assemblies expressed in permanently transfected mouse fibroblast cells. Mol Pharmacol 48:841-848.
-
(1995)
Mol Pharmacol
, vol.48
, pp. 841-848
-
-
Priestley, T.1
Laughton, P.2
Myers, J.3
Le Bourdelle, B.4
Kerby, J.5
Whiting, P.J.6
-
33
-
-
0029939653
-
Sterol biosynthesis: Strong inhibition of maize Δ5,7-sterol Δ7-reductase by novel 6-aza-B-homosteroids and other analogues of a presumptive carbocationic intermediate of the reduction reaction
-
Rahier A and Taton M (1996) Sterol biosynthesis: strong inhibition of maize Δ5,7-sterol Δ7-reductase by novel 6-aza-B-homosteroids and other analogues of a presumptive carbocationic intermediate of the reduction reaction. Biochemistry 35: 7069-7076.
-
(1996)
Biochemistry
, vol.35
, pp. 7069-7076
-
-
Rahier, A.1
Taton, M.2
-
34
-
-
0017725114
-
Effect of zuclomiphene on cholesterol formation in the developing central nervous system of the rat
-
Ramsey RB, Fredericks M, and Fischer VW (1977) Effect of zuclomiphene on cholesterol formation in the developing central nervous system of the rat. J Neurochem 28:1317-1321.
-
(1977)
J Neurochem
, vol.28
, pp. 1317-1321
-
-
Ramsey, R.B.1
Fredericks, M.2
Fischer, V.W.3
-
35
-
-
3543050868
-
Inhibition by triparanol of cholesterol formation in the brain of the newborn mouse
-
Scallen TJ, Condie RM, and Schroepfer GJ (1961) Inhibition by triparanol of cholesterol formation in the brain of the newborn mouse. J Neurochem 9:99-103.
-
(1961)
J Neurochem
, vol.9
, pp. 99-103
-
-
Scallen, T.J.1
Condie, R.M.2
Schroepfer, G.J.3
-
36
-
-
33845280171
-
Significance of slow-binding enzyme inhibition and its relationship to reaction-intermediate analogues
-
Schloss JV (1988) Significance of slow-binding enzyme inhibition and its relationship to reaction-intermediate analogues. Accounts Chem Res 21:348-353.
-
(1988)
Accounts Chem Res
, vol.21
, pp. 348-353
-
-
Schloss, J.V.1
-
37
-
-
0022621281
-
The effects of enclomiphene and zuclomiphene citrates on mouse embryos fertilized in vitro and in vivo
-
Schmidt GE, Moon HK, Mansour R, Torello L, and Friedman CI (1986) The effects of enclomiphene and zuclomiphene citrates on mouse embryos fertilized in vitro and in vivo. Am J Obstet Gynecol 154:727-736.
-
(1986)
Am J Obstet Gynecol
, vol.154
, pp. 727-736
-
-
Schmidt, G.E.1
Moon, H.K.2
Mansour, R.3
Torello, L.4
Friedman, C.I.5
-
38
-
-
9544223310
-
Emopamil-binding protein, a mammalian protein that binds a series of structurally diverse neuroprotective agents, exhibits Δ8-Δ7 isomerase activity in yeast
-
Silve S, Dupuy PH, Labit-Lebouteiller C, Kaghad M, Chalon P, Rahier A, Taton M, Lupker J, Shire D, and Loison G (1996) Emopamil-binding protein, a mammalian protein that binds a series of structurally diverse neuroprotective agents, exhibits Δ8-Δ7 isomerase activity in yeast. J Biol Chem 271:22434-22440.
-
(1996)
J Biol Chem
, vol.271
, pp. 22434-22440
-
-
Silve, S.1
Dupuy, P.H.2
Labit-Lebouteiller, C.3
Kaghad, M.4
Chalon, P.5
Rahier, A.6
Taton, M.7
Lupker, J.8
Shire, D.9
Loison, G.10
-
39
-
-
0026355311
-
Identification of Δ5,7-sterol Δ7-reductase in higher plant microsomes
-
Taton M and Rahier A (1991) Identification of Δ5,7-sterol Δ7-reductase in higher plant microsomes. Biochem Biophys Res Commun 181:465-473.
-
(1991)
Biochem Biophys Res Commun
, vol.181
, pp. 465-473
-
-
Taton, M.1
Rahier, A.2
-
40
-
-
0027724310
-
An alternative mechanism for the inhibition of cholesterol biosynthesis in hepG2 cells by n-[(1,5,9)-trimethyldecyl]-4α,10-dimethyl-8-aza-trans-decal-3β-ol (MDL 28,815)
-
van Sickle WA, Wilson PK, Wannamaker MW, Cooper JR, Flanagan MA, McCarthy JR, Bey P and Jackson RL (1993) An alternative mechanism for the inhibition of cholesterol biosynthesis in hepG2 cells by n-[(1,5,9)-trimethyldecyl]-4α,10-dimethyl-8-aza-trans-decal-3β-ol (MDL 28,815). J Pharmacol Exp Ther 267:1243-1249.
-
(1993)
J Pharmacol Exp Ther
, vol.267
, pp. 1243-1249
-
-
Van Sickle, W.A.1
Wilson, P.K.2
Wannamaker, M.W.3
Cooper, J.R.4
Flanagan, M.A.5
McCarthy, J.R.6
Bey, P.7
Jackson, R.L.8
-
41
-
-
0021320348
-
High affinity specific antiestrogen binding sites are concentrated in rough microsomal membranes of rat liver
-
Watts CKW and Sutherland RL (1984) High affinity specific antiestrogen binding sites are concentrated in rough microsomal membranes of rat liver. Biochem Biophys Res Commun 120:109-115.
-
(1984)
Biochem Biophys Res Commun
, vol.120
, pp. 109-115
-
-
Watts, C.K.W.1
Sutherland, R.L.2
|