Insulin solubility transitions by pH-dependent interactions with proinsulin C-peptide

FEBS Journal

Volumn 279, Issue 24, 2012, Pages 4589-4597

  Landreh, Michael ^a   Alvelius, Gunvor ^a   Willander, Hanna ^a   Stukenborg, Jan Bernd ^b   Söder, Olle ^b   Johansson, Jan ^a   Jörnvall, Hans ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

C peptide; diabetes; insulin; mass spectrometry; protein aggregation

Indexed keywords

C PEPTIDE; GLUTAMIC ACID; PROINSULIN; RECOMBINANT HUMAN INSULIN;

ARTICLE; ELECTRON MICROSCOPY; ELECTROSPRAY MASS SPECTROMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HORMONE STRUCTURE; INSULIN RELEASE; LIGHT SCATTERING; NUCLEAR MAGNETIC RESONANCE; PH; PRECIPITATION; PRIORITY JOURNAL; PROTEIN INTERACTION; SOLUBILITY; TURBIDIMETRY;

C-PEPTIDE; HUMANS; HYDROGEN-ION CONCENTRATION; INSULIN; SOLUBILITY;

EID: 84870539009     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/febs.12045     Document Type: Article

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