Mechanisms of thyroid hormone receptor-specific nuclear and extra nuclear actions

Molecular and Cellular Endocrinology

Volumn 213, Issue 1, 2003, Pages 1-11

  Bassett, J H Duncan ^a   Harvey, Clare B ^a   Williams, Graham R ^a  

^a HAMMERSMITH HOSPITAL   (United Kingdom)

Author keywords

Mitochondria; Non genomic action; Thyroid hormone; Thyroid hormone receptor

Indexed keywords

ADENINE NUCLEOTIDE TRANSLOCASE; CALCIUM ION; CELL NUCLEUS RECEPTOR; CYCLIC AMP; DIIODOTHYRONINE; G PROTEIN COUPLED RECEPTOR; GESTAGEN; ION CHANNEL; LIOTHYRONINE; MEMBRANE RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN; PROTEIN KINASE; PROTEIN P28; PROTEIN P46; RAF PROTEIN; RETINOID X RECEPTOR; STAT PROTEIN; STEROID HORMONE; STEROID RECEPTOR COACTIVATOR 1; THYROID HORMONE; THYROID HORMONE RECEPTOR; THYROXINE; UNCLASSIFIED DRUG;

BROWN ADIPOSE TISSUE; CELL MEMBRANE; CELL TYPE; CONFERENCE PAPER; CYTOPLASM; GENE EXPRESSION; GENETIC TRANSCRIPTION; HEART; HORMONE ACTION; HUMAN; HYPOPHYSIS; MITOCHONDRIAL GENETICS; NONHUMAN; OXIDATIVE PHOSPHORYLATION; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; THYROID GLAND; TISSUE TYPES;

EID: 1242296273     PISSN: 03037207     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mce.2003.10.033     Document Type: Conference Paper

References (81)

1. Almeida A., Orfao A., Lopez-Mediavilla C., Medina J.M. Hypothyroidism prevents postnatal changes in rat liver mitochondrial populations defined by rhodamine-123 staining. Endocrinology. 136:1995;4448-4453.
2. Aranda A., Pascual A. Nuclear hormone receptors and gene expression. Physiol. Rev. 81:2001;1269-1304.
3. Arnold S., Goglia F., Kadenbach B. 3,5-Diiodothyronine binds to subunit Va of cytochrome-c oxidase and abolishes the allosteric inhibition of respiration by ATP. Eur. J. Biochem. 252:1998;325-330.
4. Bagowski C.P., Myers J.W., Ferrell J.E. Jr. The classical progesterone receptor associates with p42 MAPK and is involved in phosphatidylinositol 3-kinase signaling in Xenopus oocytes. J. Biol. Chem. 276:2001;37708-37714.
5. Baqui M., Botero D., Gereben B., Curcio C., Harney J.W., Salvatore D., Sorimachi K., Larsen P.R., Bianco A.C. Human type 3 iodothyronine selenodeiodinase is located in the plasma membrane and undergoes rapid internalization to endosomes. J. Biol. Chem. 278:2003;1206-1211.
6. Baumann C.T., Maruvada P., Hager G.L., Yen P.M. Nuclear cytoplasmic shuttling by thyroid hormone receptors. multiple protein interactions are required for nuclear retention. J. Biol. Chem. 276:2001;11237-11245.
7. Bianco A.C., Salvatore D., Gereben B., Berry M.J., Larsen P.R. Biochemistry, cellular and molecular biology, and physiological roles of the iodothyronine selenodeiodinases. Endocr. Rev. 23:2002;38-89.
8. Casas F., Rochard P., Rodier A., Cassar-Malek I., Marchal-Victorion S., Wiesner R.J., Cabello G., Wrutniak C. A variant form of the nuclear triiodothyronine receptor c-ErbAalpha1 plays a direct role in regulation of mitochondrial RNA synthesis. Mol. Cell. Biol. 19:1999;7913-7924.
9. Casas F., Domenjoud L., Rochard P., Hatier R., Rodier A., Daury L., Bianchi A., Kremarik-Bouillaud P., Becuwe P., Keller J., Schohn H., Wrutniak-Cabello C., Cabello G., Dauca M. A 45. kDa protein related to PPARgamma2, induced by peroxisome proliferators, is located in the mitochondrial matrix FEBS Lett. 478:2000;4-8.
10. Casas F., Daury L., Grandemange S., Busson M., Seyer P., Hatier R., Carazo A., Cabello G., Wrutniak-Cabello C. Endocrine regulation of mitochondrial activity: involvement of truncated RXRalpha and c-Erb Aalpha1 proteins. FASEB J. 17:2003;426-436.
11. Castoria G., Barone M.V., Di Domenico M., Bilancio A., Ametrano D., Migliaccio A., Auricchio F. Non-transcriptional action of oestradiol and progestin triggers DNA synthesis. EMBO J. 18:1999;2500-2510.
12. Davis P.J., Davis F.B. Nongenomic actions of thyroid hormone on the heart. Thyroid. 12:2002;459-466.
13. 2(+)-ATPase activity. Endocr. Res. 15:1989;651-682.
14. Davis P.J., Shih A., Lin H.Y., Martino L.J., Davis F.B. Thyroxine promotes association of mitogen-activated protein kinase and nuclear thyroid hormone receptor (TR) and causes serine phosphorylation of TR. J. Biol. Chem. 275:2000;38032-38039.
15. de Jesus L.A., Carvalho S.D., Ribeiro M.O., Schneider M., Kim S.W., Harney J.W., Larsen P.R., Bianco A.C. The type 2 iodothyronine deiodinase is essential for adaptive thermogenesis in brown adipose tissue. J. Clin. Invest. 108:2001;1379-1385.
16. Enriquez J.A., Fernandez-Silva P., Garrido-Perez N., Lopez-Perez M.J., Perez-Martos A., Montoya J. Direct regulation of mitochondrial RNA synthesis by thyroid hormone. Mol. Cell. Biol. 19:1999;657-660.
17. 2+-fluxes in sperm. Endocrinology. 140:1999;5999-6002.
18. Feng X., Jiang Y., Meltzer P., Yen P.M. Thyroid hormone regulation of hepatic genes in vivo detected by complementary DNA microarray. Mol. Endocrinol. 14:2000;947-955.
19. Garstka H.L., Facke M., Escribano J.R., Wiesner R.J. Stoichiometry of mitochondrial transcripts and regulation of gene expression by mitochondrial transcription factor A. Biochem. Biophys. Res. Commun. 200:1994;619-626.
20. Goglia F., Lanni A., Barth J., Kadenbach B. Interaction of diiodothyronines with isolated cytochrome c oxidase. FEBS Lett. 346:1994;295-298.
21. Goglia F., Moreno M., Lanni A. Action of thyroid hormones at the cellular level: the mitochondrial target. FEBS Lett. 452:1999;115-120.
22. Gouveia C.H., Schultz J.J., Jackson D.J., Williams G.R., Brent G.A. Thyroid hormone gene targets in ROS 17/2.8 osteoblast-like cells identified by differential display analysis. Thyroid. 12:2002;663-671.
23. Hafezi-Moghadam A., Simoncini T., Yang E., Limbourg F.P., Plumier J.C., Rebsamen M.C., Hsieh C.M., Chui D.S., Thomas K.L., Prorock A.J., Laubach V.E., Moskowitz M.A., French B.A., Ley K., Liao J.K. Acute cardiovascular protective effects of corticosteroids are mediated by non-transcriptional activation of endothelial nitric oxide synthase. Nat. Med. 8:2002;473-479.
24. Haynes M.P., Sinha D., Russell K.S., Collinge M., Fulton D., Morales-Ruiz M., Sessa W.C., Bender J.R. Membrane estrogen receptor engagement activates endothelial nitric oxide synthase via the PI3-kinase-Akt pathway in human endothelial cells. Circ. Res. 87:2000;677-682.
25. Hennemann G., Docter R., Friesema E.C., de Jong M., Krenning E.P., Visser T.J. Plasma membrane transport of thyroid hormones and its role in thyroid hormone metabolism and bioavailability. Endocr. Rev. 22:2001;451-476.
26. Hu X., Lazar M.A. The CoRNR motif controls the recruitment of corepressors by nuclear hormone receptors. Nature. 402:1999;93-96.
27. Iglesias T., Caubin J., Zaballos A., Bernal J., Munoz A. Identification of the mitochondrial NADH dehydrogenase subunit 3 (ND3) as a thyroid hormone regulated gene by whole genome PCR analysis. Biochem. Biophys. Res. Commun. 210:1995;995-1000.
28. Jones K.E., Brubaker J.H., Chin W.W. Evidence that phosphorylation events participate in thyroid hormone action. Endocrinology. 134:1994;543-548.
29. Kato S., Endoh H., Masuhiro Y., Kitamoto T., Uchiyama S., Sasaki H., Masushige S., Gotoh Y., Nishida E., Kawashima H., Metzger D., Chambon P. Activation of the estrogen receptor through phosphorylation by mitogen-activated protein kinase. Science. 270:1995;1491-1494.
30. Katz D., Reginato M.J., Lazar M.A. Functional regulation of thyroid hormone receptor variant TR alpha 2 by phosphorylation. Mol. Cell. Biol. 15:1995;2341-2348.
31. Kavok N.S., Krasilnikova O.A., Babenko N.A. Thyroxine signal transduction in liver cells involves phospholipase C and phospholipase D activation. genomic independent action of thyroid hormone. BMC Cell. Biol. 2:2001;5.
32. Krstic M.D., Rogatsky I., Yamamoto K.R., Garabedian M.J. Mitogen-activated and cyclin-dependent protein kinases selectively and differentially modulate transcriptional enhancement by the glucocorticoid receptor. Mol. Cell. Biol. 17:1997;3947-3954.
33. Lakatos P., Stern P.H. Evidence for direct non-genomic effects of triiodothyronine on bone rudiments in rats: stimulation of the inositol phosphate second messenger system. Acta Endocrinol. (Copenhagen). 125:1991;603-608.
34. Leitman D.C., Costa C.H., Graf H., Baxter J.D., Ribeiro R.C. Thyroid hormone activation of transcription is potentiated by activators of cAMP-dependent protein kinase. J. Biol. Chem. 271:1996;21950-21955.
35. Li L., Haynes M.P., Bender J.R. Plasma membrane localization and function of the estrogen receptor alpha variant (ER46) in human endothelial cells. Proc. Natl. Acad. Sci. U.S.A. 100:2003;4807-4812.
36. Lin H.Y., Yen P.M., Davis F.B., Davis P.J. Protein synthesis-dependent potentiation by thyroxine of antiviral activity of interferon-gamma. Am. J. Physiol. 273:1997;C1225-C1232.
37. Lin H.Y., Davis F.B., Gordinier J.K., Martino L.J., Davis P.J. Thyroid hormone induces activation of mitogen-activated protein kinase in cultured cells. Am. J. Physiol. 276:1999;C1014-C1024.
38. Losel R., Wehling M. Nongenomic actions of steroid hormones. Nat. Rev. Mol. Cell. Biol. 4:2003;46-56.
39. Losel R., Feuring M., Wehling M. Non-genomic aldosterone action: from the cell membrane to human physiology. J. Steroid Biochem. Mol. Biol. 83:2002;167-171.
40. Lynch M.A., Andrews J.F., Moore R.E. Low doses of T3 induce a rapid metabolic response in young lambs. Horm. Metab. Res. 17:1985;63-66.
41. Maller J.L. Signal transduction. fishing at the cell surface. Science. 300:2003;594-595.
42. Morel G., Ricard-Blum S., Ardail D. Kinetics of internalization and subcellular binding sites for T3 in mouse liver. Biol. Cell. 86:1996;167-174.
43. Moreno M., Lanni A., Lombardi A., Goglia F. How the thyroid controls metabolism in the rat: different roles for triiodothyronine and diiodothyronines. J. Physiol. 505(Pt 2):1997;529-538.
44. Mutvei A., Husman B., Andersson G., Nelson B.D. Thyroid hormone and not growth hormone is the principle regulator of mammalian mitochondrial biogenesis. Acta Endocrinol. (Copenhagen). 121:1989a;223-228.
45. Mutvei A., Kuzela S., Nelson B.D. Control of mitochondrial transcription by thyroid hormone. Eur. J. Biochem. 180:1989b;235-240.
46. Nemere I., Yoshimoto Y., Norman A.W. Calcium transport in perfused duodena from normal chicks: enhancement within fourteen minutes of exposure to 1,25-dihydroxyvitamin D3. Endocrinology. 115:1984;1476-1483.
47. Osman R.A., Andria M.L., Jones A.D., Meizel S. Steroid induced exocytosis: the human sperm acrosome reaction. Biochem. Biophys. Res. Commun. 160:1989;828-833.
48. Pietras R.J., Szego C.M. Endometrial cell calcium and oestrogen action. Nature. 253:1975;357-359.
49. Pietras R.J., Szego C.M. Specific binding sites for oestrogen at the outer surfaces of isolated endometrial cells. Nature. 265:1977;69-72.
50. Pillar T.M., Seitz H.J. Thyroid hormone and gene expression in the regulation of mitochondrial respiratory function. Eur. J. Endocrinol. 136:1997;231-239.
51. Razandi M., Oh P., Pedram A., Schnitzer J., Levin E.R. ERs associate with and regulate the production of caveolin: implications for signaling and cellular actions. Mol. Endocrinol. 16:2002;100-115.
52. Razandi M., Alton G., Pedram A., Ghonshani S., Webb P., Levin E.R. Identification of a structural determinant necessary for the localization and function of estrogen receptor alpha at the plasma membrane. Mol. Cell. Biol. 23:2003;1633-1646.
53. Ritchie J.W., Shi Y.B., Hayashi Y., Baird F.E., Muchekehu R.W., Christie G.R., Taylor P.M. A role for thyroid hormone transporters in transcriptional regulation by thyroid hormone receptors. Mol. Endocrinol. 17:2003;653-661.
54. 2+ from rat heart and liver mitochondria following the interaction of thyroid hormone with the adenine nucleotide translocase. Thyroid. 6:1996;513-519.
55. Rosenfeld M.G., Glass C.K. Coregulator codes of transcriptional regulation by nuclear receptors. J. Biol. Chem. 276:2001;36865-36868.
56. Russell K.S., Haynes M.P., Sinha D., Clerisme E., Bender J.R. Human vascular endothelial cells contain membrane binding sites for estradiol, which mediate rapid intracellular signaling. Proc. Natl. Acad. Sci. U.S.A. 97:2000;5930-5935.
57. Scheller K., Sekeris C.E., Krohne G., Hock R., Hansen I.A., Scheer U. Localization of glucocorticoid hormone receptors in mitochondria of human cells. Eur. J. Cell. Biol. 79:2000;299-307.
58. Schmitt A., Nebreda A.R. Inhibition of Xenopus oocyte meiotic maturation by catalytically inactive protein kinase A. Proc. Natl. Acad. Sci. U.S.A. 99:2002;4361-4366.
59. Schmidt B.M., Martin N., Georgens A.C., Tillmann H.C., Feuring M., Christ M., Wehling M. Nongenomic cardiovascular effects of triiodothyronine in euthyroid male volunteers. J. Clin. Endocrinol. Metab. 87:2002;1681-1686.
60. Segal J. Action of the thyroid hormone at the level of the plasma membrane. Endocr. Res. 15:1989;619-649.
61. Shaul P.W. Rapid activation of endothelial nitric oxide synthase by estrogen. Steroids. 64:1999;28-34.
62. Shih A., Lin H.Y., Davis F.B., Davis P.J. Thyroid hormone promotes serine phosphorylation of p53 by mitogen-activated protein kinase. Biochemistry. 40:2001;2870-2878.
63. Soboll S., Horst C., Hummerich H., Schumacher J.P., Seitz H.J. Mitochondrial metabolism in different thyroid states. Biochem. J. 281(Part 1):1992;171-173.
64. Sterling K., Brenner M.A. Thyroid hormone action: effect of triiodothyronine on mitochondrial adenine nucleotide translocase in vivo and in vitro. Metabolism. 44:1995;193-199.
65. Sterling K., Campbell G.A., Brenner M.A. Purification of the mitochondrial triiodothyronine (T3) receptor from rat liver. Acta Endocrinol. (Copenhagen). 105:1984;391-397.
66. Sterling K., Milch P.O., Brenner M.A., Lazarus J.H. Thyroid hormone action: the mitochondrial pathway. Science. 197:1977;996-999.
67. Storey N.M., O'Bryan J.P., Armstrong D.L. Rac and Rho mediate opposing hormonal regulation of the ether-a-go-go-related potassium channel. Curr. Biol. 12:2002;27-33.
68. Thomas W.E., Crespo-Armas A., Mowbray J. The influence of nanomolar calcium ions and physiological levels of thyroid hormone on oxidative phosphorylation in rat liver mitochondria. a possible signal amplification control mechanism. Biochem. J. 247:1987;315-320.
69. Ting Y.T., Bhat M.K., Wong R., Cheng S. Tissue-specific stabilization of the thyroid hormone beta1 nuclear receptor by phosphorylation. J. Biol. Chem. 272:1997;4129-4134.
70. 2+ in cat atrial myocytes. J. Physiol. 546:2003;491-499.
71. Watters J.J., Campbell J.S., Cunningham M.J., Krebs E.G., Dorsa D.M. Rapid membrane effects of steroids in neuroblastoma cells: effects of estrogen on mitogen activated protein kinase signalling cascade and c-fos immediate early gene transcription. Endocrinology. 138:1997;4030-4033.
72. Wiesner R.J., Kurowski T.T., Zak R. Regulation by thyroid hormone of nuclear and mitochondrial genes encoding subunits of cytochrome-c oxidase in rat liver and skeletal muscle. Mol. Endocrinol. 6:1992;1458-1467.
73. Wrutniak C., Cabello G. Influence of hypothyroidism on the lipolytic activity of norepinephrine in the newborn lamb. J. Endocrinol. 108:1986;451-454.
74. Wrutniak C., Cabello G. Influence of tri-iodothyronine or lipid administration on the response of the pituitary-thyroid axis to exposure to cold in the newborn lamb. J. Endocrinol. 121:1989;361-365.
75. Wrutniak C., Cassar-Malek I., Marchal S., Rascle A., Heusser S., Keller J.M., Flechon J., Dauca M., Samarut J., Ghysdael J., Cabello G. A 43-kDa protein related to c-Erb a alpha 1 is located in the mitochondrial matrix of rat liver. J. Biol. Chem. 270:1995;16347-16354.
76. Wrutniak C., Rochard P., Casas F., Fraysse A., Charrier J., Cabello G. Physiological importance of the T3 mitochondrial pathway. Ann. N.Y. Acad. Sci. 839:1998;93-100.
77. Wrutniak-Cabello C., Casas F., Cabello G. Thyroid hormone action in mitochondria. J. Mol. Endocrinol. 26:2001;67-77.
78. Wyckoff M.H., Chambliss K.L., Mineo C., Yuhanna I.S., Mendelsohn M.E., Mumby S.M., Shaul P.W. Plasma membrane estrogen receptors are coupled to endothelial nitric-oxide synthase through Galpha(i). J. Biol. Chem. 276:2001;27071-27076.
79. Yen P.M. Physiological and molecular basis of thyroid hormone action. Physiol. Rev. 81:2001;1097-1142.
80. Zhu Y., Bond J., Thomas P. Identification, classification, and partial characterization of genes in humans and other vertebrates homologous to a fish membrane progestin receptor. Proc. Natl. Acad. Sci. U.S.A. 100:2003a;2237-2242.
81. Zhu Y., Rice C.D., Pang Y., Pace M., Thomas P. Cloning, expression, and characterization of a membrane progestin receptor and evidence it is an intermediary in meiotic maturation of fish oocytes. Proc. Natl. Acad. Sci. U.S.A. 100:2003b;2231-2236.