Waterborne exposure to microcystin-LR alters thyroid hormone levels and gene transcription in the hypothalamic-pituitary-thyroid axis in zebrafish larvae

Chemosphere

Volumn 87, Issue 11, 2012, Pages 1301-1307

  Yan, Wei ^a   Zhou, Youxiang ^a   Yang, Jie ^a   Li, Shuqian ^a   Hu, Dingjin ^a   Wang, Jianghua ^b   Chen, Jun ^c   Li, Guangyu ^b  

^a INSTITUTE OF PLANT PROTECTION   (China)

^b HUAZHONG AGRICULTURAL UNIVERSITY   (China)

^c INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

Author keywords

Gene expression; Hypothalamic pituitary thyroid axis; MCLR; Zebrafish

Indexed keywords

AMINO ACIDS; GENE EXPRESSION; HORMONES; POLYMERASE CHAIN REACTION; SODIUM COMPOUNDS;

CONCENTRATION-DEPENDENT MANNERS; CORTICOTROPIN-RELEASING FACTORS; GENE EXPRESSION LEVELS; HYPOTHALAMIC-PITUITARY-THYROID AXIS; MCLR; QUANTITATIVE REAL TIME PCR; THYROID STIMULATING HORMONES; ZEBRAFISH;

TRANSCRIPTION;

CORTICOTROPIN RELEASING FACTOR; IODOTHYRONINE; IODOTHYRONINE DEIODINASE; LIOTHYRONINE; MICROCYSTIN LR; SODIUM IODIDE SYMPORTER; THYROGLOBULIN; THYROID HORMONE; THYROTROPIN; UNCLASSIFIED DRUG;

CONCENTRATION (COMPOSITION); CYPRINID; ENDOCRINE DISRUPTOR; FRESHWATER ENVIRONMENT; GENE EXPRESSION; GENOTOXICITY; GROWTH RATE; HOMEOSTASIS; HORMONE; LARVAL DEVELOPMENT; MOLECULAR ANALYSIS; PEPTIDE; POLLUTION EFFECT; POLLUTION EXPOSURE; POLYMERASE CHAIN REACTION; TOXIC SUBSTANCE;

ARTICLE; DOWN REGULATION; EMBRYO; GENE EXPRESSION; GENETIC TRANSCRIPTION; GROWTH RETARDATION; HYPOTHALAMUS HYPOPHYSIS THYROID SYSTEM; LARVA; NONHUMAN; NUCLEOTIDE SEQUENCE; REAL TIME POLYMERASE CHAIN REACTION; UPREGULATION; ZEBRA FISH;

DANIO RERIO;

EID: 84862829100     PISSN: 00456535     EISSN: 18791298     Source Type: Journal    
DOI: 10.1016/j.chemosphere.2012.01.041     Document Type: Article

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