DeltaPhage -A novel helper phage for high-valence pIX phagemid display

Nucleic Acids Research

Volumn 40, Issue 16, 2012, Pages

  Nilssen, Nicolay R ^a,b   Frigstad, Terje ^a,c,d   Pollmann, Sylvie ^d   Roos, Norbert ^b   Bogen, Bjarne ^a,c   Sandlie, Inger ^a,b,c   Loset, Geir A ^a,b,c,d  

^a OSLO UNIVERSITY HOSPITAL   (Norway)

^b UNIVERSITY OF OSLO   (Norway)

^c OSLO UNIVERSITY HOSPITAL   (Norway)

^d Nextera AS   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; COAT PROTEIN;

ARTICLE; BACTERIAL STRAIN; DELTAPHAGE; DISPLAY SYSTEM; ESCHERICHIA COLI; GENE MUTATION; MICROBIAL DIVERSITY; MUTAGENESIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PHAGE DISPLAY; PHAGEMID; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FOLDING; START CODON; WILD TYPE;

ANIMALS; ANTIGENS; BACTERIOPHAGES; CELL LINE; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENETIC VECTORS; HELPER VIRUSES; MICE; PEPTIDE LIBRARY; RECEPTORS, ANTIGEN, T-CELL;

EID: 84870496337     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gks341     Document Type: Article

References (55)

1. Bratkovic, T. (2010) Progress in phage display: evolution of the technique and its applications. Cell. Mol. Life Sci., 67, 749-767.
2. Rakonjac, J., Bennett, N.J., Spagnuolo, J., Gagic, D. and Russel, M. (2011) Filamentous bacteriophage: biology, phage display and nanotechnology applications. Curr. Issues Mol. Biol., 13, 51-76.
3. Bradbury, A.R. and Marks, J.D. (2004) Antibodies from phage antibody libraries. J. Immunol. Methods, 290, 29-49.
4. Dubel, S., Stoevesandt, O., Taussig, M.J. and Hust, M. (2010) Generating recombinant antibodies to the complete human proteome. Trends Biotechnol., 28, 333-339.
5. Bradbury, A.R., Sidhu, S., Dubel, S. and McCafferty, J. (2011) Beyond natural antibodies: the power of in vitro display technologies. Nat. Biotechnol., 29, 245-254.
6. Kretzschmar, T. and Geiser, M. (1995) Evaluation of antibodies fused to minor coat protein III and major coat protein VIII of bacteriophage M13. Gene, 155, 61-65.
7. Pavoni, E., Monteriu, G., Cianfriglia, M. and Minenkova, O. (2007) New display vector reduces biological bias for expression of antibodies in E. coli. Gene, 391, 120-129.
8. O'Connell, D., Becerril, B., Roy-Burman, A., Daws, M. and Marks, J.D. (2002) Phage versus phagemid libraries for generation of human monoclonal antibodies. J. Mol. Biol., 321, 49-56.
9. Hust, M., Meysing, M., Schirrmann, T., Selke, M., Meens, J., Gerlach, G.F. and Dubel, S. (2006) Enrichment of open reading frames presented on bacteriophage M13 using hyperphage. BioTechniques, 41, 335-342.
10. Jespers, L., Schon, O., Famm, K. and Winter, G. (2004) Aggregation-resistant domain antibodies selected on phage by heat denaturation. Nat. Biotechnol., 22, 1161-1165.
11. Becerril, B., Poul, M.A. and Marks, J.D. (1999) Toward selection of internalizing antibodies from phage libraries. Biochem. Biophys. Res. Commun., 255, 386-393.
12. Rondot, S., Koch, J., Breitling, F. and Dubel, S. (2001) A helper phage to improve single-chain antibody presentation in phage display. Nat. Biotechnol., 19, 75-78.
13. Baek, H., Suk, K.H., Kim, Y.H. and Cha, S. (2002) An improved helper phage system for efficient isolation of specific antibody molecules in phage display. Nucleic Acids Res., 30, e18.
14. Soltes, G., Barker, H., Marmai, K., Pun, E., Yuen, A. and Wiersma, E.J. (2003) A new helper phage and phagemid vector system improves viral display of antibody Fab fragments and avoids propagation of insert-less virions. J. Immunol. Methods, 274, 233-244.
15. Løset, G.A., Kristinsson, S.G. and Sandlie, I. (2008) Reliable titration of filamentous bacteriophages independent of pIII fusion moiety and genome size by using trypsin to restore wild-type pIII phenotype. BioTechniques, 44, 551-554.
16. Shi, B., Wang, H., Guo, S., Xu, Y., Li, Z. and Gu, J. (2007) Protein III-based single-chain antibody phage display using bacterial cells bearing an additional genome of a gene-III-lacking helper phage. BioTechniques, 42, 760-765.
17. Zanconato, S., Minervini, G., Poli, I. and Lucrezia, D.D. (2011) Selection dynamic of Escherichia coli host in M13 combinatorial peptide phage display libraries. Biosci. Biotechnol. Biochem., 75, 812-815.
18. Cwirla, S.E., Peters, E.A., Barrett, R.W. and Dower, W.J. (1990) Peptides on phage: a vast library of peptides for identifying ligands. PNAS, 87, 6378-6382.
19. Lowman, H.B., Bass, S.H., Simpson, N. and Wells, J.A. (1991) Selecting high-affinity binding proteins by monovalent phage display. Biochemistry, 30, 10832-10838.
20. de Haard, H.J., van Neer, N., Reurs, A., Hufton, S.E., Roovers, R.C., Henderikx, P., de Bruine, A.P., Arends, J.W. and Hoogenboom, H.R. (1999) A large non-immunized human Fab fragment phage library that permits rapid isolation and kinetic analysis of high affinity antibodies. J. Biol. Chem., 274, 18218-18230.
21. Simons, G.F., Konings, R.N. and Schoenmakers, J.G. (1981) Genes VI, VII, and IX of phage M13 code for minor capsid proteins of the virion. PNAS, 78, 4194-4198.
22. Gao, C., Mao, S., Kaufmann, G., Wirsching, P., Lerner, R.A. and Janda, K.D. (2002) A method for the generation of combinatorial antibody libraries using pIX phage display. PNAS, 99, 12612-12616.
23. Shi, L., Wheeler, J.C., Sweet, R.W., Lu, J., Luo, J., Tornetta, M., Whitaker, B., Reddy, R., Brittingham, R., Borozdina, L. et al. (2010) De novo selection of high-affinity antibodies from synthetic fab libraries displayed on phage as pIX fusion proteins. J. Mol. Biol., 397, 385-396.
24. Tornetta, M., Baker, S., Whitaker, B., Lu, J., Chen, Q., Pisors, E., Shi, L., Luo, J., Sweet, R. and Tsui, P. (2010) Antibody Fab display and selection through fusion to the pIX coat protein of filamentous phage. J. Immunol. Methods, 360, 39-46.
25. Løset, G.A ., Roos, N., Bogen, B. and Sandlie, I. (2011) Expanding the versatility of phage display II: improved affinity selection of folded domains on protein VII and IX of the filamentous phage. PLoS One, 6, e17433.
26. Endemann, H. and Model, P. (1995) Location of filamentous phage minor coat proteins in phage and in infected cells. J. Mol. Biol., 250, 496-506.
27. Gao, C., Mao, S., Lo, C.H., Wirsching, P., Lerner, R.A. and Janda, K.D. (1999) Making artificial antibodies: a format for phage display of combinatorial heterodimeric arrays. PNAS, 96, 6025-6030.
28. Ploss, M. and Kuhn, A. (2011) Membrane insertion and assembly of epitope-tagged gp9 at the tip of the M13 phage. BMC Microbiol., 11, 211.
29. Bossi, L. (1983) Context effects: translation of UAG codon by suppressor tRNA is affected by the sequence following UAG in the message. J. Mol. Biol., 164, 73-87.
30. Soltes, G., Hust, M., Ng, K.K., Bansal, A., Field, J., Stewart, D.I., Dubel, S., Cha, S. and Wiersma, E.J. (2007) On the influence of vector design on antibody phage display. J. Biotechnol., 127, 626-637.
31. Løset, G.A., Lunde, E., Bogen, B., Brekke, O.H. and Sandlie, I. (2007) Functional phage display of two murine a/b T-cell receptors is strongly dependent on fusion format, mode and periplasmic folding assistance. Protein Eng. Des, Sel., 20461-472.
32. Bogen, B., Snodgrass, R., Briand, J.P. and Hannestad, K. (1986) Synthetic peptides and beta-chain gene rearrangements reveal a diversified T cell repertoire for a lambda light chain third hypervariable region. Eur. J. Immunol., 16, 1379-1384.
33. Bogen, B., Lauritzsen, G.F. and Weiss, S. (1990) A stimulatory monoclonal antibody detecting T cell receptor diversity among idiotype-specific, major histocompatibility complex-restricted T cell clones. Eur. J. Immunol., 20, 2359-2362.
34. Michaelsen, T.E., Aase, A., Westby, C. and Sandlie, I. (1990) Enhancement of complement activation and cytolysis of human IgG3 by deletion of hinge exons. Scand. J. Immunol., 32, 517-528.
35. Nakela, O., Kaartinen, M., Pelkonen, J.L. and Karjalainen, K. (1978) Inheritance of antibody specificity V. Anti-2-phenyloxazolone in the mouse. J. Exp. Med., 148, 1644-1660.
36. Sambrook, J. and Russell, D.W. (2001) Molecular Cloning: A Laboratory Manual, 3 edn. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
37. Marks, J.D., Hoogenboom, H.R., Bonnert, T.P., McCafferty, J., Griffiths, A.D. and Winter, G. (1991) By-passing immunization. Human antibodies from V-gene libraries displayed on phage. J. Mol. Biol., 222, 581-597.
38. Mount, J.D., Samoylova, T.I., Morrison, N.E., Cox, N.R., Baker, H.J. and Petrenko, V.A. (2004) Cell targeted phagemid rescued by preselected landscape phage. Gene, 341, 59-65.
39. Welschof, M., Terness, P., Kipriyanov, S.M., Stanescu, D., Breitling, F., Dorsam, H., Dubel, S., Little, M. and Opelz, G. (1997) The antigen-binding domain of a human IgG-anti-F(ab')2 autoantibody. PNAS, 94, 1902-1907.
40. Koch, J., Breitling, F. and Dubel, S. (2000) Rapid titration of multiple samples of filamentous bacteriophage (M13) on nitrocellulose filters. BioTechniques, 29, 1196-1198.
41. Løset, G.A., Kristinsson, S.G. and Sandlie, I. (2008) Reliable titration of filamentous bacteriophages independent of pIII fusion moiety and genome size by using trypsin to restore wild-type pIII phenotype. Biotechniques, 44, 551-552, 554.
42. Weibel, E.R. (1979) Practical Methods for Biological Morphometry. Academic Press, London.
43. Vieira, J. and Messing, J. (1987) Production of single-stranded plasmid DNA. Methods Enzymol., 153, 3-11.
44. Lopez, J. and Webster, R.E. (1983) Morphogenesis of filamentous bacteriophage f1: orientation of extrusion and production of polyphage. Virology, 127, 177-193.
45. Barbas, C.F. (2001) Phage display: A Laboratory Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
46. Marks, J.D., Griffiths, A.D., Malmqvist, M., Clackson, T.P., Bye, J.M. and Winter, G. (1992) By-passing immunization: building high affinity human antibodies by chain shuffling. Biotechnology, 10, 779-783.
47. Løset, G.A., Roux, K.H., Zhu, P., Michaelsen, T.E. and Sandlie, I. (2004) Differential segmental flexibility and reach dictate the antigen binding mode of chimeric IgD and IgM: implications for the function of the B cell receptor. J. Immunol., 172, 2925-2934.
48. Kramer, R.A., Cox, F., van der Horst, M., van der Oudenrijn, S., Res, P.C., Bia, J., Logtenberg, T. and de Kruif, J. (2003) A novel helper phage that improves phage display selection efficiency by preventing the amplification of phages without recombinant protein. Nucleic Acids Res., 31, e59.
49. Soltes, G., Hust, M., Ng, K.K.Y., Bansal, A., Field, J., Stewart, D.I.H., Dubel, S., Cha, S. and Wiersma, E.J. (2007) On the influence of vector design on antibody phage display. J. Biotechol., 127, 626-637.
50. Rheinnecker, M., Hardt, C., Ilag, L.L., Kufer, P., Gruber, R., Hoess, A., Lupas, A., Rottenberger, C., Pluckthun, A. and Pack, P. (1996) Multivalent antibody fragments with high functional affinity for a tumor-associated carbohydrate antigen. J. Immunol., 157, 2989-2997.
51. Pack, P., Muller, K., Zahn, R. and Pluckthun, A. (1995) Tetravalent miniantibodies with high avidity assembling in Escherichia coli. J. Mol. Biol., 246, 28-34.
52. Kwasnikowski, P., Kristensen, P. and Markiewicz, W.T. (2005) Multivalent display system on filamentous bacteriophage pVII minor coat protein. J. Immunol. Methods, 307, 135-143.
53. Huovinen, T., Sanmark, H., Yla-Pelto, J., Vehniainen, M. and Lamminmaki, U. (2010) Oligovalent Fab display on M13 phage improved by directed evolution. Mol. Biotechnol., 44, 221-231.
54. Kuba, H. and Furukawa, K. (2009) An optimized procedure for efficient phage display of antibody fragments with a low folding efficiency. Protein Expr. Purif., 65, 148-153.
55. Rothe, C., Urlinger, S., Lohning, C., Prassler, J., Stark, Y., Jager, U., Hubner, B., Bardroff, M., Pradel, I., Boss, M. et al. (2008) The human combinatorial antibody library HuCAL GOLD combines diversification of all six CDRs according to the natural immune system with a novel display method for efficient selection of high-affinity antibodies. J. Mol. Biol., 376, 1182-1200.