-
1
-
-
33845886915
-
Abdominal obesity and metabolic syndrome
-
Despres JP, Lemieux I: Abdominal obesity and metabolic syndrome. Nature 2006, 444:881-887.
-
(2006)
Nature
, vol.444
, pp. 881-887
-
-
Despres, J.P.1
Lemieux, I.2
-
2
-
-
34247193564
-
Metabolic syndrome: Is it a syndrome? Does it matter?
-
Kahn R: Metabolic syndrome: is it a syndrome? Does it matter? Circulation 2007, 115:1806-1810.
-
(2007)
Circulation
, vol.115
, pp. 1806-1810
-
-
Kahn, R.1
-
3
-
-
0031851293
-
Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: Diagnosis and classification of diabetes mellitus provisional report of a WHO consultation
-
Alberti KG, Zimmet PZ: Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus provisional report of a WHO consultation. Diabet Med 1998, 15:539-553.
-
(1998)
Diabet Med
, vol.15
, pp. 539-553
-
-
Alberti, K.G.1
Zimmet, P.Z.2
-
4
-
-
0035897696
-
Executive Summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III)
-
Executive Summary of The Third Report of The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, And Treatment of High Blood Cholesterol In Adults (Adult Treatment Panel III). JAMA 2001, 285:2486-2497.
-
(2001)
JAMA
, vol.285
, pp. 2486-2497
-
-
-
5
-
-
25144459980
-
The metabolic syndrome - A new worldwide definition
-
DOI 10.1016/S0140-6736(05)67402-8, PII S0140673605674028
-
Alberti KG, Zimmet P, Shaw J: The metabolic syndrome - a new worldwide definition. Lancet 2005, 366:1059-1062. (Pubitemid 41338752)
-
(2005)
Lancet
, vol.366
, Issue.9491
, pp. 1059-1062
-
-
Alberti, K.G.M.M.1
Zimmet, P.2
Shaw, J.3
-
6
-
-
59049085845
-
Genetics of the cardiometabolic syndrome: New insights and therapeutic implications
-
Sookoian S, Pirola CJ: Genetics of the cardiometabolic syndrome: new insights and therapeutic implications. Ther Adv Cardiovasc Dis 2007, 1:37-47.
-
(2007)
Ther Adv Cardiovasc Dis
, vol.1
, pp. 37-47
-
-
Sookoian, S.1
Pirola, C.J.2
-
7
-
-
72449197565
-
Novel functions for small RNA molecules
-
Zhang C: Novel functions for small RNA molecules. Curr Opin Mol Ther 2009, 11:641-651.
-
(2009)
Curr Opin Mol Ther
, vol.11
, pp. 641-651
-
-
Zhang, C.1
-
8
-
-
34249700597
-
Epigenetic programming by maternal behavior and pharmacological intervention. Nature versus nurture: Let's call the whole thing off
-
Weaver IC: Epigenetic programming by maternal behavior and pharmacological intervention. Nature versus nurture: let's call the whole thing off. Epigenetics 2007, 2:22-28.
-
(2007)
Epigenetics
, vol.2
, pp. 22-28
-
-
Weaver, I.C.1
-
9
-
-
67849130563
-
ToppGene Suite for gene list enrichment analysis and candidate gene prioritization
-
This article demonstrates the bioinformatic tool for gene list functional enrichment, candidate gene prioritization, and identification and prioritization of novel disease candidate genes in the interactome
-
Chen J, Bardes EE, Aronow BJ, et al.: ToppGene Suite for gene list enrichment analysis and candidate gene prioritization. Nucleic Acids Res 2009, 37:W305-W311. This article demonstrates the bioinformatic tool for gene list functional enrichment, candidate gene prioritization, and identification and prioritization of novel disease candidate genes in the interactome.
-
(2009)
Nucleic Acids Res
, vol.37
-
-
Chen, J.1
Bardes, E.E.2
Aronow, B.J.3
-
10
-
-
67249147301
-
Gene prioritization based on biological plausibility over genome wide association studies renders new loci associated with type 2 diabetes
-
Sookoian S, Gianotti TF, Schuman M, et al.: Gene prioritization based on biological plausibility over genome wide association studies renders new loci associated with type 2 diabetes. Genet Med 2009, 11:338-343.
-
(2009)
Genet Med
, vol.11
, pp. 338-343
-
-
Sookoian, S.1
Gianotti, T.F.2
Schuman, M.3
-
11
-
-
71649108660
-
Influence of hepatocyte nuclear factor 4α (HNF4α) gene variants on the risk of type 2 diabetes: A meta-analysis in 49,577 individuals
-
Sookoian S, Gemma C, Pirola CJ: Influence of hepatocyte nuclear factor 4α (HNF4α) gene variants on the risk of type 2 diabetes: a meta-analysis in 49,577 individuals. Mol Genet Metab 2010, 99:80-89.
-
(2010)
Mol Genet Metab
, vol.99
, pp. 80-89
-
-
Sookoian, S.1
Gemma, C.2
Pirola, C.J.3
-
12
-
-
77952469210
-
Role of genetic variation in insulin-like growth factor 1 receptor on insulin resistance and arterial hypertension
-
Sookoian S, Gianotti TF, Gemma C, et al.: Role of genetic variation in insulin-like growth factor 1 receptor on insulin resistance and arterial hypertension. J Hypertens 2010, 28:1194-1202.
-
(2010)
J Hypertens
, vol.28
, pp. 1194-1202
-
-
Sookoian, S.1
Gianotti, T.F.2
Gemma, C.3
-
13
-
-
67249117049
-
Potential etiologic and functional implications of genome-wide association loci for human diseases and traits
-
Hindorff LA, Sethupathy P, Junkins HA, et al.: Potential etiologic and functional implications of genome-wide association loci for human diseases and traits. Proc Natl Acad Sci U S A 2009, 106:9362-9367.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 9362-9367
-
-
Hindorff, L.A.1
Sethupathy, P.2
Junkins, H.A.3
-
14
-
-
33947121582
-
Short allele of serotonin transporter gene promoter is a risk factor for obesity in adolescents
-
Sookoian S, Gemma C, Garcia SI, et al.: Short allele of serotonin transporter gene promoter is a risk factor for obesity in adolescents. Obesity (Silver Spring) 2007, 15:271-276. (Pubitemid 46407306)
-
(2007)
Obesity
, vol.15
, Issue.2
, pp. 271-276
-
-
Sookoian, S.1
Gemma, C.2
Garcia, S.I.3
Gianotti, T.F.4
Dieuzeide, G.5
Roussos, A.6
Tonietti, M.7
Trifone, L.8
Kanevsky, D.9
Gonzalez, C.D.10
Pirola, C.J.11
-
15
-
-
39449137183
-
Contribution of the functional 5-HTTLPR variant of the SLC6A4 gene to obesity risk in male adults
-
DOI 10.1038/oby.2007.64, PII OBY200764
-
Sookoian S, Gianotti TF, Gemma C, et al.: Contribution of the functional 5-HTTLPR variant of the SLC6A4 gene to obesity risk in male adults. Obesity (Silver Spring) 2008, 16:488-491. (Pubitemid 351271937)
-
(2008)
Obesity
, vol.16
, Issue.2
, pp. 488-491
-
-
Sookoian, S.1
Gianotti, T.F.2
Gemma, C.3
Burgueo, A.4
Pirola, C.J.5
-
16
-
-
77955152755
-
Nuclear receptors linking circadian rhythms and cardiometabolic control
-
Duez H, Staels B: Nuclear receptors linking circadian rhythms and cardiometabolic control. Arterioscler Thromb Vasc Biol 2010, 30:1529-1534.
-
(2010)
Arterioscler Thromb Vasc Biol
, vol.30
, pp. 1529-1534
-
-
Duez, H.1
Staels, B.2
-
17
-
-
45749158901
-
Genetic variants of Clock transcription factor are associated with individual susceptibility to obesity
-
Sookoian S, Gemma C, Gianotti TF, et al.: Genetic variants of Clock transcription factor are associated with individual susceptibility to obesity. Am J Clin Nutr 2008, 87:1606-1615. (Pubitemid 351872621)
-
(2008)
American Journal of Clinical Nutrition
, vol.87
, Issue.6
, pp. 1606-1615
-
-
Sookoian, S.1
Gemma, C.2
Gianotti, T.F.3
Burgueno, A.4
Castano, G.5
Pirola, C.J.6
-
18
-
-
34548480183
-
Common genetic variation in CLOCK transcription factor are associated with nonalcoholic fatty liver disease
-
Sookoian S, Castano G, Gemma C, et al.: Common genetic variations in CLOCK transcription factor are associated with nonalcoholic fatty liver disease. World J Gastroenterol 2007, 13:4242-4248. (Pubitemid 47377164)
-
(2007)
World Journal of Gastroenterology
, vol.13
, Issue.31
, pp. 4242-4248
-
-
Sookoian, S.1
Castano, G.2
Gemma, C.3
Gianotti, T.F.4
Pirola, C.J.5
-
19
-
-
74049138315
-
Cumulative effects and predictive value of common obesity-susceptibility variants identified by genomewide association studies
-
Li S, Zhao JH, Luan J, et al.: Cumulative effects and predictive value of common obesity-susceptibility variants identified by genomewide association studies. Am J Clin Nutr 2010, 91:184-190.
-
(2010)
Am J Clin Nutr
, vol.91
, pp. 184-190
-
-
Li, S.1
Zhao, J.H.2
Luan, J.3
-
20
-
-
7244232606
-
2-adrenergic receptor and neuropeptide Y genes influences LDL-cholesterol in hypertension
-
DOI 10.1161/01.HYP.0000143844.81979.61
-
Tomaszewski M, Charchar FJ, Lacka B, et al.: Epistatic interaction between β2-adrenergic receptor and neuropeptide Y genes influences LDL-cholesterol in hypertension. Hypertension 2004, 44:689-694. (Pubitemid 39435240)
-
(2004)
Hypertension
, vol.44
, Issue.5
, pp. 689-694
-
-
Tomaszewski, M.1
Charchar, F.J.2
Lacka, B.3
Pesonen, U.4
Wang, W.Y.S.5
Zukowska-Szczechowska, E.6
Grzeszczak, W.7
Dominiczak, A.F.8
-
21
-
-
34447298876
-
Epistatic interaction between haplotypes of the ghrelin ligand and receptor genes influence susceptibility to myocardial infarction and coronary artery disease
-
DOI 10.1093/hmg/ddm033
-
Baessler A, Fischer M, Mayer B, et al.: Epistatic interaction between haplotypes of the ghrelin ligand and receptor genes influence susceptibility to myocardial infarction and coronary artery disease. Hum Mol Genet 2007, 16:887-899. (Pubitemid 47062734)
-
(2007)
Human Molecular Genetics
, vol.16
, Issue.8
, pp. 887-899
-
-
Baessler, A.1
Fischer, M.2
Mayer, B.3
Koehler, M.4
Wiedmann, S.5
Stark, K.6
Doering, A.7
Erdmann, J.8
Riegger, G.9
Schunkert, H.10
Kwitek, A.E.11
Hengstenberg, C.12
-
22
-
-
34447133527
-
Epistatic effect of cholesteryl ester transfer protein and hepatic lipase on serum high-density lipoprotein cholesterol levels
-
DOI 10.1210/jc.2007-0269
-
Isaacs A, Aulchenko YS, Hofman A, et al.: Epistatic effect of cholesteryl ester transfer protein and hepatic lipase on serum highdensity lipoprotein cholesterol levels. J Clin Endocrinol Metab 2007, 92:2680-2687. (Pubitemid 47037376)
-
(2007)
Journal of Clinical Endocrinology and Metabolism
, vol.92
, Issue.7
, pp. 2680-2687
-
-
Isaacs, A.1
Aulchenko, Y.S.2
Hofman, A.3
Sijbrands, E.J.G.4
Sayed-Tabatabaei, F.A.5
Klungel, O.H.6
Maitland-Van, D.Z.A.-H.7
Stricker, B.H.Ch.8
Oostra, B.A.9
Witteman, J.C.M.10
Van Duijn, C.M.11
-
23
-
-
34547415510
-
Genetic epistasis in the VLDL catabolic pathway is associated with deleterious variations on triglyceridemia in obese subjects
-
DOI 10.1038/sj.ijo.0803586, PII 0803586
-
Brisson D, St-Pierre J, Santure M, et al.: Genetic epistasis in the VLDL catabolic pathway is associated with deleterious variations on triglyceridemia in obese subjects. Int J Obes (Lond) 2007, 31:1325-1333. (Pubitemid 47172622)
-
(2007)
International Journal of Obesity
, vol.31
, Issue.8
, pp. 1325-1333
-
-
Brisson, D.1
St-Pierre, J.2
Santure, M.3
Hudson, T.J.4
Despres, J.P.5
Vohl, M.C.6
Gaudet, D.7
-
24
-
-
77954978940
-
Gene-gene interaction between serotonin transporter (SLC6A4) and CLOCK modulates the risk of metabolic syndrome in rotating shiftworkers
-
Sookoian S, Gianotti TF, Burgueño A, Pirola CJ: Gene-gene interaction between serotonin transporter (SLC6A4) and CLOCK modulates the risk of metabolic syndrome in rotating shiftworkers. Chronobiol Int 2010, 27:1202-1218.
-
(2010)
Chronobiol Int
, vol.27
, pp. 1202-1218
-
-
Sookoian, S.1
Gianotti, T.F.2
Burgueño, A.3
Pirola, C.J.4
-
25
-
-
41149172495
-
Epigenetic regulation of PPARGC1A in human type 2 diabetic islets and effect on insulin secretion
-
Ling C, Del Guerra S, Lupi R, et al.: Epigenetic regulation of PPARGC1A in human type 2 diabetic islets and effect on insulin secretion. Diabetologia 2008, 51:615-622.
-
(2008)
Diabetologia
, vol.51
, pp. 615-622
-
-
Ling, C.1
Del Guerra, S.2
Lupi, R.3
-
26
-
-
67349133607
-
Maternal pregestational BMI is associated with methylation of the PPARGC1A promoter in newborns
-
Silver Spring
-
Gemma C, Sookoian S, Alvarinas J, et al.: Maternal pregestational BMI is associated with methylation of the PPARGC1A promoter in newborns. Obesity (Silver Spring) 2009, 17:1032-1039.
-
(2009)
Obesity
, vol.17
, pp. 1032-1039
-
-
Gemma, C.1
Sookoian, S.2
Alvarinas, J.3
-
27
-
-
77950627693
-
Methylation of TFAM gene promoter in peripheral white blood cells is associated with insulin resistance in adolescents
-
Gemma C, Sookoian S, Dieuzeide G, et al.: Methylation of TFAM gene promoter in peripheral white blood cells is associated with insulin resistance in adolescents. Mol Genet Metab 2010, 100:83-87.
-
(2010)
Mol Genet Metab
, vol.100
, pp. 83-87
-
-
Gemma, C.1
Sookoian, S.2
Dieuzeide, G.3
-
28
-
-
33846312172
-
Mitochondrial DNA depletion in small- and large-for-gestational-age newborns
-
Gemma C, Sookoian S, Alvarinas J, et al.: Mitochondrial DNA depletion in small- and large-for-gestational-age newborns. Obesity (Silver Spring) 2006, 14:2193-2199. (Pubitemid 46121975)
-
(2006)
Obesity
, vol.14
, Issue.12
, pp. 2193-2199
-
-
Gemma, C.1
Sookoian, S.2
Alvarinas, J.3
Garcia, S.I.4
Quintana, L.5
Kanevsky, D.6
Gonzalez, C.D.7
Pirola, C.J.8
-
29
-
-
46249096857
-
A decreased mitochondrial DNA content is related to insulin resistance in adolescents
-
DOI 10.1038/oby.2008.253, PII OBY2008253
-
Gianotti TF, Sookoian S, Dieuzeide G, et al.: A decreased mitochondrial DNA content is related to insulin resistance in adolescents. Obesity 2008, 16:1591-1595. (Pubitemid 351915123)
-
(2008)
Obesity
, vol.16
, Issue.7
, pp. 1591-1595
-
-
Gianotti, T.F.1
Sookoian, S.2
Dieuzeide, G.3
Garcia, S.I.4
Gemma, C.5
Gonzalez, C.D.6
Pirola, C.J.7
-
30
-
-
73249133400
-
Epigenetics: A molecular link between environmental factors and type 2 diabetes
-
Ling C, Groop L: Epigenetics: a molecular link between environmental factors and type 2 diabetes. Diabetes 2009, 58:2718-2725.
-
(2009)
Diabetes
, vol.58
, pp. 2718-2725
-
-
Ling, C.1
Groop, L.2
-
31
-
-
34547727263
-
Human microRNA-155 on chromosome 21 differentially interacts with its polymorphic target in the AGTR1 3′ untranslated region: A mechanism for functional single-nucleotide polymorphisms related to phenotypes
-
DOI 10.1086/519979
-
Sethupathy P, Borel C, Gagnebin M, et al.: Human microRNA-155 on chromosome 21 differentially interacts with its polymorphic target in the AGTR1 3′ untranslated region: a mechanism for functional single-nucleotide polymorphisms related to phenotypes. Am J Hum Genet 2007, 81:405-413. (Pubitemid 47236088)
-
(2007)
American Journal of Human Genetics
, vol.81
, Issue.2
, pp. 405-413
-
-
Sethupathy, P.1
Borel, C.2
Gagnebin, M.3
Grant, G.R.4
Deutsch, S.5
Elton, T.S.6
Hatzigeorgiou, A.G.7
Antonarakis, S.E.8
-
32
-
-
16844374196
-
A1166C angiotensin II type 1 receptor gene polymorphism may predict hemodynamic response to losartan in patients with cirrhosis and portal hypertension
-
DOI 10.1111/j.1572-0241.2005.41168.x
-
Sookoian S, Castano G, Garcia SI, et al.: A1166C angiotensin II type 1 receptor gene polymorphism may predict hemodynamic response to losartan in patients with cirrhosis and portal hypertension. Am J Gastroenterol 2005, 100:636-642. (Pubitemid 40487564)
-
(2005)
American Journal of Gastroenterology
, vol.100
, Issue.3
, pp. 636-642
-
-
Sookoian, S.1
Castano, G.2
Garcia, S.I.3
Viudez, P.4
Gonzalez, C.5
Pirola, C.J.6
-
33
-
-
61649092260
-
Mechanistic insights into the link between a polymorphism of the 3?UTR of the SLC7A1 gene and hypertension
-
Yang Z, Kaye DM: Mechanistic insights into the link between a polymorphism of the 3?UTR of the SLC7A1 gene and hypertension. Hum Mutat 2009, 30:328-333.
-
(2009)
Hum Mutat
, vol.30
, pp. 328-333
-
-
Yang, Z.1
Kaye, D.M.2
-
34
-
-
33947712377
-
Identification of a novel polymorphism in the 3′UTR of the L-arginine transporter gene SLC7A1: Contribution to hypertension and endothelial dysfunction
-
DOI 10.1161/CIRCULATIONAHA.106.665836
-
Yang Z, Venardos K, Jones E, et al.: Identification of a novel polymorphism in the 3′UTR of the L-arginine transporter gene SLC7A1: contribution to hypertension and endothelial dysfunction. Circulation 2007, 115:1269-1274. (Pubitemid 46594771)
-
(2007)
Circulation
, vol.115
, Issue.10
, pp. 1269-1274
-
-
Yang, Z.1
Venardos, K.2
Jones, E.3
Morris, B.J.4
Chin-Dusting, J.5
Kaye, D.M.6
-
35
-
-
77953787211
-
MiR-33 contributes to the regulation of cholesterol homeostasis
-
The authors demonstrated that miR-33 appears to regulate both HDL biogenesis in the liver and cellular cholesterol efflux
-
Rayner KJ, Suarez Y, Davalos A, et al.: MiR-33 contributes to the regulation of cholesterol homeostasis. Science 2010, 328:1570-1573. The authors demonstrated that miR-33 appears to regulate both HDL biogenesis in the liver and cellular cholesterol efflux.
-
(2010)
Science
, vol.328
, pp. 1570-1573
-
-
Rayner, K.J.1
Suarez, Y.2
Davalos, A.3
-
36
-
-
77951092180
-
Targeting of mRNAs by multiple miRNAs: The next step
-
Peter ME: Targeting of mRNAs by multiple miRNAs: the next step. Oncogene 2010, 29:2161-2164.
-
(2010)
Oncogene
, vol.29
, pp. 2161-2164
-
-
Peter, M.E.1
-
37
-
-
77954269901
-
The GeneMANIA prediction server: Biological network integration for gene prioritization and predicting gene function
-
Warde-Farley D, Donaldson SL, Comes O, et al: The GeneMANIA prediction server: biological network integration for gene prioritization and predicting gene function. Nucleic Acids Res. 2010:W214-220.
-
(2010)
Nucleic Acids Res
-
-
Warde-Farley, D.1
Donaldson, S.L.2
Comes, O.3
|