-
1
-
-
40849147041
-
EGFR antagonists in cancer treatment
-
Ciardiello, F.; Tortora, G., EGFR antagonists in cancer treatment. N Engl J Med, 2008, 358, 1160-1174.
-
(2008)
N Engl J Med
, vol.358
, pp. 1160-1174
-
-
Ciardiello, F.1
Tortora, G.2
-
2
-
-
25844460747
-
Development of strategies for the use of anti-growth factor treatments
-
Jones, H.E.; Gee, J.M.; Taylor, K.M.; Barrow, D.; Williams, H.D.; Rubini, M.; Nicholson, R.I., Development of strategies for the use of anti-growth factor treatments. Endocr Relat Cancer, 2005, 12 Suppl 1, S173-182.
-
(2005)
Endocr Relat Cancer
, vol.12
, Issue.SUPPL. 1
-
-
Jones, H.E.1
Gee, J.M.2
Taylor, K.M.3
Barrow, D.4
Williams, H.D.5
Rubini, M.6
Nicholson, R.I.7
-
3
-
-
75549083827
-
EGFR signaling and drug discovery
-
Lurje, G.; Lenz, H.J., EGFR signaling and drug discovery. Oncology, 2009, 77, 400-410.
-
(2009)
Oncology
, vol.77
, pp. 400-410
-
-
Lurje, G.1
Lenz, H.J.2
-
4
-
-
46849085176
-
Imaging and cancer: A review
-
Fass, L., Imaging and cancer: a review. Mol Oncol, 2008, 2, 115-152.
-
(2008)
Mol Oncol
, vol.2
, pp. 115-152
-
-
Fass, L.1
-
5
-
-
36849056542
-
Multimodality imaging of the HER-kinase axis in cancer
-
Cai, W.; Niu, G.; Chen, X., Multimodality imaging of the HER-kinase axis in cancer. Eur J Nucl Med Mol Imaging, 2008, 35, 186-208.
-
(2008)
Eur J Nucl Med Mol Imaging
, vol.35
, pp. 186-208
-
-
Cai, W.1
Niu, G.2
Chen, X.3
-
6
-
-
33745828702
-
EGF-ERBB signalling: Towards the systems level
-
Citri, A.; Yarden, Y., EGF-ERBB signalling: towards the systems level. Nat Rev Mol Cell Biol, 2006, 7, 505-516.
-
(2006)
Nat Rev Mol Cell Biol
, vol.7
, pp. 505-516
-
-
Citri, A.1
Yarden, Y.2
-
7
-
-
0035256698
-
Untangling the ErbB signalling network
-
Yarden, Y.; Sliwkowski, M.X., Untangling the ErbB signalling network. Nat Rev Mol Cell Biol, 2001, 2, 127-137.
-
(2001)
Nat Rev Mol Cell Biol
, vol.2
, pp. 127-137
-
-
Yarden, Y.1
Sliwkowski, M.X.2
-
8
-
-
33645795739
-
EGFR as a target: Rationale for therapy
-
Wujcik, D., EGFR as a target: rationale for therapy. Semin Oncol Nurs, 2006, 22, 5-9.
-
(2006)
Semin Oncol Nurs
, vol.22
, pp. 5-9
-
-
Wujcik, D.1
-
9
-
-
2342492317
-
Review of epidermal growth factor receptor biology
-
Herbst, R.S., Review of epidermal growth factor receptor biology. Int J Radiat Oncol Biol Phys, 2004, 59, 21-26.
-
(2004)
Int J Radiat Oncol Biol Phys
, vol.59
, pp. 21-26
-
-
Herbst, R.S.1
-
10
-
-
77956868654
-
Epidermal growth factor receptor in glioma: Signal transduction, neuropathology, imaging, and radioresistance
-
Hatanpaa, K.J.; Burma, S.; Zhao, D.W.; Habib, A.A., Epidermal Growth Factor Receptor in Glioma: Signal Transduction, Neuropathology, Imaging, and Radioresistance. Neoplasia, 2010, 12, 675-684.
-
(2010)
Neoplasia
, vol.12
, pp. 675-684
-
-
Hatanpaa, K.J.1
Burma, S.2
Zhao, D.W.3
Habib, A.A.4
-
11
-
-
0038449116
-
EGF receptor as a therapeutic target
-
Levitzki, A., EGF receptor as a therapeutic target. Lung Cancer, 2003, 41 Suppl 1, S9-14.
-
(2003)
Lung Cancer
, vol.41
, Issue.SUPPL. 1
-
-
Levitzki, A.1
-
12
-
-
33748134662
-
The role of the epidermal growth factor receptor in breast cancer
-
Chan, S.K.; Hill, M.E.; Gullick, W.J., The role of the epidermal growth factor receptor in breast cancer. J Mammary Gland Biol Neoplasia, 2006, 11, 3-11.
-
(2006)
J Mammary Gland Biol Neoplasia
, vol.11
, pp. 3-11
-
-
Chan, S.K.1
Hill, M.E.2
Gullick, W.J.3
-
13
-
-
77958484636
-
Molecular imaging of HER2-positive breast cancer: A step toward an individualized 'image and treat' strategy
-
Capala, J.; Bouchelouche, K., Molecular imaging of HER2-positive breast cancer: a step toward an individualized 'image and treat' strategy. Curr Opin Oncol, 2010, 22, 559-566.
-
(2010)
Curr Opin Oncol
, vol.22
, pp. 559-566
-
-
Capala, J.1
Bouchelouche, K.2
-
14
-
-
0035037366
-
Molecular targets for breast cancer therapy and prevention
-
Bange, J.; Zwick, E.; Ullrich, A., Molecular targets for breast cancer therapy and prevention. Nat Med, 2001, 7, 548-552.
-
(2001)
Nat Med
, vol.7
, pp. 548-552
-
-
Bange, J.1
Zwick, E.2
Ullrich, A.3
-
15
-
-
5144226211
-
PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients
-
Nagata, Y.; Lan, K.H.; Zhou, X.; Tan, M.; Esteva, F.J.; Sahin, A.A.; Klos, K.S.; Li, P.; Monia, B.P.; Nguyen, N.T.; Hortobagyi, G.N.; Hung, M.C.; Yu, D., PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients. Cancer Cell, 2004, 6, 117-127.
-
(2004)
Cancer Cell
, vol.6
, pp. 117-127
-
-
Nagata, Y.1
Lan, K.H.2
Zhou, X.3
Tan, M.4
Esteva, F.J.5
Sahin, A.A.6
Klos, K.S.7
Li, P.8
Monia, B.P.9
Nguyen, N.T.10
Hortobagyi, G.N.11
Hung, M.C.12
Yu, D.13
-
16
-
-
0036467826
-
Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer
-
Vogel, C.L.; Cobleigh, M.A.; Tripathy, D.; Gutheil, J.C.; Harris, L.N.; Fehrenbacher, L.; Slamon, D.J.; Murphy, M.; Novotny, W.F.; Burchmore, M.; Shak, S.; Stewart, S.J.; Press, M., Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer. J Clin Oncol, 2002, 20, 719-726.
-
(2002)
J Clin Oncol
, vol.20
, pp. 719-726
-
-
Vogel, C.L.1
Cobleigh, M.A.2
Tripathy, D.3
Gutheil, J.C.4
Harris, L.N.5
Fehrenbacher, L.6
Slamon, D.J.7
Murphy, M.8
Novotny, W.F.9
Burchmore, M.10
Shak, S.11
Stewart, S.J.12
Press, M.13
-
17
-
-
26844536978
-
Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer
-
Romond, E.H.; Perez, E.A.; Bryant, J.; Suman, V.J.; Geyer, C.E., Jr.; Davidson, N.E.; Tan-Chiu, E.; Martino, S.; Paik, S.; Kaufman, P.A.; Swain, S.M.; Pisansky, T.M.; Fehrenbacher, L.; Kutteh, L.A.; Vogel, V.G.; Visscher, D.W.; Yothers, G.; Jenkins, R.B.; Brown, A.M.; Dakhil, S.R.; Mamounas, E.P.; Lingle, W.L.; Klein, P.M.; Ingle, J.N.; Wolmark, N., Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer. N Engl J Med, 2005, 353, 1673-1684.
-
(2005)
N Engl J Med
, vol.353
, pp. 1673-1684
-
-
Romond, E.H.1
Perez, E.A.2
Bryant, J.3
Suman, V.J.4
Geyer Jr., C.E.5
Davidson, N.E.6
Tan-Chiu, E.7
Martino, S.8
Paik, S.9
Kaufman, P.A.10
Swain, S.M.11
Pisansky, T.M.12
Fehrenbacher, L.13
Kutteh, L.A.14
Vogel, V.G.15
Visscher, D.W.16
Yothers, G.17
Jenkins, R.B.18
Brown, A.M.19
Dakhil, S.R.20
Mamounas, E.P.21
Lingle, W.L.22
Klein, P.M.23
Ingle, J.N.24
Wolmark, N.25
more..
-
18
-
-
58149237085
-
HER-2/neu expression in primary and metastatic breast cancer
-
Lower, E.E.; Glass, E.; Blau, R.; Harman, S., HER-2/neu expression in primary and metastatic breast cancer. Breast Cancer Res Treat, 2009, 113, 301-306.
-
(2009)
Breast Cancer Res Treat
, vol.113
, pp. 301-306
-
-
Lower, E.E.1
Glass, E.2
Blau, R.3
Harman, S.4
-
19
-
-
28644436100
-
Multivalent avimer proteins evolved by exon shuffling of a family of human receptor domains
-
Silverman, J.; Liu, Q.; Bakker, A.; To, W.; Duguay, A.; Alba, B.M.; Smith, R.; Rivas, A.; Li, P.; Le, H.; Whitehorn, E.; Moore, K.W.; Swimmer, C.; Perlroth, V.; Vogt, M.; Kolkman, J.; Stemmer, W.P., Multivalent avimer proteins evolved by exon shuffling of a family of human receptor domains. Nat Biotechnol, 2005, 23, 1556-1561.
-
(2005)
Nat Biotechnol
, vol.23
, pp. 1556-1561
-
-
Silverman, J.1
Liu, Q.2
Bakker, A.3
To, W.4
Duguay, A.5
Alba, B.M.6
Smith, R.7
Rivas, A.8
Le Li, P.H.9
Whitehorn, E.10
Moore, K.W.11
Swimmer, C.12
Perlroth, V.13
Vogt, M.14
Kolkman, J.15
Stemmer, W.P.16
-
20
-
-
33745108827
-
Tumor targeting by an aptamer
-
Hicke, B.J.; Stephens, A.W.; Gould, T.; Chang, Y.F.; Lynott, C.K.; Heil, J.; Borkowski, S.; Hilger, C.S.; Cook, G.; Warren, S.; Schmidt, P.G., Tumor targeting by an aptamer. J Nucl Med, 2006, 47, 668-678.
-
(2006)
J Nucl Med
, vol.47
, pp. 668-678
-
-
Hicke, B.J.1
Stephens, A.W.2
Gould, T.3
Chang, Y.F.4
Lynott, C.K.5
Heil, J.6
Borkowski, S.7
Hilger, C.S.8
Cook, G.9
Warren, S.10
Schmidt, P.G.11
-
21
-
-
0030835822
-
Binding proteins selected from combinatorial libraries of an alpha-helical bacterial receptor domain
-
Nord, K.; Gunneriusson, E.; Ringdahl, J.; Stahl, S.; Uhlen, M.; Nygren, P.A., Binding proteins selected from combinatorial libraries of an alpha-helical bacterial receptor domain. Nat Biotechnol, 1997, 15, 772-777.
-
(1997)
Nat Biotechnol
, vol.15
, pp. 772-777
-
-
Nord, K.1
Gunneriusson, E.2
Ringdahl, J.3
Stahl, S.4
Uhlen, M.5
Nygren, P.A.6
-
22
-
-
33947318463
-
Affibody molecules: New protein domains for molecular imaging and targeted tumor therapy
-
Nilsson, F.Y.; Tolmachev, V., Affibody molecules: new protein domains for molecular imaging and targeted tumor therapy. Curr Opin Drug Discov Devel, 2007, 10, 167-175.
-
(2007)
Curr Opin Drug Discov Devel
, vol.10
, pp. 167-175
-
-
Nilsson, F.Y.1
Tolmachev, V.2
-
23
-
-
34047155118
-
Affibody molecules: Potential for in vivo imaging of molecular targets for cancer therapy
-
Tolmachev, V.; Orlova, A.; Nilsson, F.Y.; Feldwisch, J.; Wennborg, A.; Abrahmsen, L., Affibody molecules: potential for in vivo imaging of molecular targets for cancer therapy. Expert Opin Biol Ther, 2007, 7, 555-568.
-
(2007)
Expert Opin Biol Ther
, vol.7
, pp. 555-568
-
-
Tolmachev, V.1
Orlova, A.2
Nilsson, F.Y.3
Feldwisch, J.4
Wennborg, A.5
Abrahmsen, L.6
-
24
-
-
79952118497
-
Radionuclide molecular imaging using Affibody molecules
-
Ahlgren, S.; Tolmachev, V., Radionuclide molecular imaging using Affibody molecules. Curr Pharm Biotechnol, 2010, 11, 581-589.
-
(2010)
Curr Pharm Biotechnol
, vol.11
, pp. 581-589
-
-
Ahlgren, S.1
Tolmachev, V.2
-
25
-
-
34249055896
-
Quantitative PET of EGFR expression in xenograft-bearing mice using 64Cu-labeled cetuximab, a chimeric anti-EGFR monoclonal antibody
-
Cai, W.; Chen, K.; He, L.; Cao, Q.; Koong, A.; Chen, X., Quantitative PET of EGFR expression in xenograft-bearing mice using 64Cu-labeled cetuximab, a chimeric anti-EGFR monoclonal antibody. Eur J Nucl Med Mol Imaging, 2007, 34, 850-858.
-
(2007)
Eur J Nucl Med Mol Imaging
, vol.34
, pp. 850-858
-
-
Cai, W.1
Chen, K.2
He, L.3
Cao, Q.4
Koong, A.5
Chen, X.6
-
26
-
-
0027929973
-
Strategy for boron neutron capture therapy against tumor cells with over-expression of the epidermal growth factor-receptor
-
Carlsson, J.; Gedda, L.; Gronvik, C.; Hartman, T.; Lindstrom, A.; Lindstrom, P.; Lundqvist, H.; Lovqvist, A.; Malmqvist, J.; Olsson, P.; et al., Strategy for boron neutron capture therapy against tumor cells with over-expression of the epidermal growth factor-receptor. Int J Radiat Oncol Biol Phys, 1994, 30, 105-115.
-
(1994)
Int J Radiat Oncol Biol Phys
, vol.30
, pp. 105-115
-
-
Carlsson, J.1
Gedda, L.2
Gronvik, C.3
Hartman, T.4
Lindstrom, A.5
Lindstrom, P.6
Lundqvist, H.7
Lovqvist, A.8
Malmqvist, J.9
Olsson, P.10
-
27
-
-
0034102191
-
A comparison of EGF and MAb 528 labeled with 111In for imaging human breast cancer
-
Reilly, R.M.; Kiarash, R.; Sandhu, J.; Lee, Y.W.; Cameron, R.G.; Hendler, A.; Vallis, K.; Gariepy, J., A comparison of EGF and MAb 528 labeled with 111In for imaging human breast cancer. J Nucl Med, 2000, 41, 903-911.
-
(2000)
J Nucl Med
, vol.41
, pp. 903-911
-
-
Reilly, R.M.1
Kiarash, R.2
Sandhu, J.3
Lee, Y.W.4
Cameron, R.G.5
Hendler, A.6
Vallis, K.7
Gariepy, J.8
-
28
-
-
33644818017
-
Preparation and evaluation of (68)Ga-DOTA-hEGF for visualization of EGFR expression in malignant tumors
-
Velikyan, I.; Sundberg, A.L.; Lindhe, O.; Hoglund, A.U.; Eriksson, O.; Werner, E.; Carlsson, J.; Bergstrom, M.; Langstrom, B.; Tolmachev, V., Preparation and evaluation of (68)Ga-DOTA-hEGF for visualization of EGFR expression in malignant tumors. J Nucl Med, 2005, 46, 1881-1888.
-
(2005)
J Nucl Med
, vol.46
, pp. 1881-1888
-
-
Velikyan, I.1
Sundberg, A.L.2
Lindhe, O.3
Hoglund, A.U.4
Eriksson, O.5
Werner, E.6
Carlsson, J.7
Bergstrom, M.8
Langstrom, B.9
Tolmachev, V.10
-
29
-
-
43849098417
-
In vivo and in vitro uptake of 111In, delivered with the affibody molecule (ZEGFR:955)2, in EGFR expressing tumour cells
-
Nordberg, E.; Orlova, A.; Friedman, M.; Tolmachev, V.; Stahl, S.; Nilsson, F.Y.; Glimelius, B.; Carlsson, J., In vivo and in vitro uptake of 111In, delivered with the affibody molecule (ZEGFR:955)2, in EGFR expressing tumour cells. Oncol Rep, 2008, 19, 853-857.
-
(2008)
Oncol Rep
, vol.19
, pp. 853-857
-
-
Nordberg, E.1
Orlova, A.2
Friedman, M.3
Tolmachev, V.4
Stahl, S.5
Nilsson, F.Y.6
Glimelius, B.7
Carlsson, J.8
-
30
-
-
77952565937
-
Small-animal PET imaging of human epidermal growth factor receptor positive tumor with a 64Cu labeled affibody protein
-
Miao, Z.; Ren, G.; Liu, H.; Jiang, L.; Cheng, Z., Small-animal PET imaging of human epidermal growth factor receptor positive tumor with a 64Cu labeled affibody protein. Bioconjug Chem, 2010, 21, 947-954.
-
(2010)
Bioconjug Chem
, vol.21
, pp. 947-954
-
-
Miao, Z.1
Ren, G.2
Liu, H.3
Jiang, L.4
Cheng, Z.5
-
31
-
-
43749125020
-
Evaluation of [(18)F]gefitinib as a molecular imaging probe for the assessment of the epidermal growth factor receptor status in malignant tumors
-
Su, H.; Seimbille, Y.; Ferl, G.Z.; Bodenstein, C.; Fueger, B.; Kim, K.J.; Hsu, Y.T.; Dubinett, S.M.; Phelps, M.E.; Czernin, J.; Weber, W.A., Evaluation of [(18)F]gefitinib as a molecular imaging probe for the assessment of the epidermal growth factor receptor status in malignant tumors. Eur J Nucl Med Mol Imaging, 2008, 35, 1089-1099.
-
(2008)
Eur J Nucl Med Mol Imaging
, vol.35
, pp. 1089-1099
-
-
Su, H.1
Seimbille, Y.2
Ferl, G.Z.3
Bodenstein, C.4
Fueger, B.5
Kim, K.J.6
Hsu, Y.T.7
Dubinett, S.M.8
Phelps, M.E.9
Czernin, J.10
Weber, W.A.11
-
32
-
-
66649121433
-
Development and characterization of clinical-grade 89Zr-trastuzumab for HER2/neu immunoPET imaging
-
Dijkers, E.C.; Kosterink, J.G.; Rademaker, A.P.; Perk, L.R.; van Dongen, G.A.; Bart, J.; de Jong, J.R.; de Vries, E.G.; Lub-de Hooge, M.N., Development and characterization of clinical-grade 89Zr-trastuzumab for HER2/neu immunoPET imaging. J Nucl Med, 2009, 50, 974-981.
-
(2009)
J Nucl Med
, vol.50
, pp. 974-981
-
-
Dijkers, E.C.1
Kosterink, J.G.2
Rademaker, A.P.3
Perk, L.R.4
Van Dongen, G.A.5
Bart, J.6
De Jong, J.R.7
De Vries, E.G.8
Lub-De Hooge, M.N.9
-
33
-
-
77951474500
-
Biodistribution of 89Zr-trastuzumab and PET imaging of HER2-positive lesions in patients with metastatic breast cancer
-
Dijkers, E.C.; Oude Munnink, T.H.; Kosterink, J.G.; Brouwers, A.H.; Jager, P.L.; de Jong, J.R.; van Dongen, G.A.; Schroder, C.P.; Lub-de Hooge, M.N.; de Vries, E.G., Biodistribution of 89Zr-trastuzumab and PET imaging of HER2-positive lesions in patients with metastatic breast cancer. Clin Pharmacol Ther, 2010, 87, 586-592.
-
(2010)
Clin Pharmacol Ther
, vol.87
, pp. 586-592
-
-
Dijkers, E.C.1
Oude Munnink, T.H.2
Kosterink, J.G.3
Brouwers, A.H.4
Jager, P.L.5
De Jong, J.R.6
Van Dongen, G.A.7
Schroder, C.P.8
Lub-De Hooge, M.N.9
De Vries, E.G.10
-
34
-
-
2542643923
-
Imaging the pharmacodynamics of HER2 degradation in response to Hsp90 inhibitors
-
Smith-Jones, P.M.; Solit, D.B.; Akhurst, T.; Afroze, F.; Rosen, N.; Larson, S.M., Imaging the pharmacodynamics of HER2 degradation in response to Hsp90 inhibitors. Nat Biotechnol, 2004, 22, 701-706.
-
(2004)
Nat Biotechnol
, vol.22
, pp. 701-706
-
-
Smith-Jones, P.M.1
Solit, D.B.2
Akhurst, T.3
Afroze, F.4
Rosen, N.5
Larson, S.M.6
-
35
-
-
79952721597
-
Evaluation of the anti-HER2 C6.5 diabody as a PET radiotracer to monitor HER2 status and predict response to trastuzumab treatment
-
Reddy, S.; Shaller, C.C.; Doss, M.; Shchaveleva, I.; Marks, J.D.; Yu, J.Q.; Robinson, M.K., Evaluation of the anti-HER2 C6.5 diabody as a PET radiotracer to monitor HER2 status and predict response to trastuzumab treatment. Clin Cancer Res, 2011, 17, 1509-1520.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 1509-1520
-
-
Reddy, S.1
Shaller, C.C.2
Doss, M.3
Shchaveleva, I.4
Marks, J.D.5
Yu, J.Q.6
Robinson, M.K.7
-
36
-
-
77953927395
-
Molecular imaging of HER2-expressing malignant tumors in breast cancer patients using synthetic 111In- or 68Galabeled affibody molecules
-
Baum, R.P.; Prasad, V.; Muller, D.; Schuchardt, C.; Orlova, A.; Wennborg, A.; Tolmachev, V.; Feldwisch, J., Molecular imaging of HER2-expressing malignant tumors in breast cancer patients using synthetic 111In- or 68Galabeled affibody molecules. J Nucl Med, 2010, 51, 892-897.
-
(2010)
J Nucl Med
, vol.51
, pp. 892-897
-
-
Baum, R.P.1
Prasad, V.2
Muller, D.3
Schuchardt, C.4
Orlova, A.5
Wennborg, A.6
Tolmachev, V.7
Feldwisch, J.8
-
37
-
-
67649882899
-
Establishment of multiple color in vivo molecular fluorescence imaging guided real-time surgery for the removal HER2 specific micrometastasis
-
Longmire M, K.N., Ogawa M, Choyke PL, Kobayashi H., Establishment of multiple color in vivo molecular fluorescence imaging guided real-time surgery for the removal HER2 specific micrometastasis. Cancer Science, 2009, 100(6), 1099-1104.
-
(2009)
Cancer Science
, vol.100
, Issue.6
, pp. 1099-1104
-
-
Longmire, M.K.N.1
Ogawa, M.2
Choyke, P.L.3
Kobayashi, H.4
-
38
-
-
65349110396
-
Multi-targeted multi-color in vivo optical imaging in a model of disseminated peritoneal ovarian cancer
-
Kosaka, N.; Ogawa, M.; Longmire, M.R.; Choyke, P.L.; Kobayashi, H., Multi-targeted multi-color in vivo optical imaging in a model of disseminated peritoneal ovarian cancer. J Biomed Opt, 2009, 14.
-
(2009)
J Biomed Opt
, pp. 14
-
-
Kosaka, N.1
Ogawa, M.2
Longmire, M.R.3
Choyke, P.L.4
Kobayashi, H.5
-
39
-
-
84856096764
-
Cancer cell-selective in vivo near infrared photoimmunotherapy targeting specific membrane molecules
-
in press
-
Mitsunaga M, O.M., Kosaka N, Rosenburm LT, Choyke PL, Kobayashi H., Cancer Cell-Selective In Vivo Near Infrared Photoimmunotherapy Targeting Specific Membrane Molecules. Nature Medicine; in press, 2011.
-
(2011)
Nature Medicine
-
-
Mitsunaga, M.O.M.1
Kosaka, N.2
Rosenburm, L.T.3
Choyke, P.L.4
Kobayashi, H.5
-
40
-
-
79958123433
-
Clinicopathological and prognostic significance of EGFR over-expression in esophageal squamous cell carcinoma: A meta-analysis
-
Yu, W.W.; Guo, Y.M.; Zhu, M.; Cai, X.W.; Zhu, Z.F.; Zhao, W.X.; Fu, X.L., Clinicopathological and prognostic significance of EGFR over-expression in esophageal squamous cell carcinoma: a meta-analysis. Hepatogastroenterology, 2011, 58, 426-431.
-
(2011)
Hepatogastroenterology
, vol.58
, pp. 426-431
-
-
Yu, W.W.1
Guo, Y.M.2
Zhu, M.3
Cai, X.W.4
Zhu, Z.F.5
Zhao, W.X.6
Fu, X.L.7
-
41
-
-
34249821046
-
Spectral fluorescence molecular imaging of lung metastases targeting HER2/neu
-
Koyama, Y.; Hama, Y.; Urano, Y.; Nguyen, D.M.; Choyke, P.L.; Kobayashi, H., Spectral fluorescence molecular imaging of lung metastases targeting HER2/neu. Clin Cancer Res, 2007, 13, 2936-2945.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 2936-2945
-
-
Koyama, Y.1
Hama, Y.2
Urano, Y.3
Nguyen, D.M.4
Choyke, P.L.5
Kobayashi, H.6
-
42
-
-
37149038059
-
In vivo molecular imaging to diagnose and subtype tumors through receptor-targeted optically labeled monoclonal antibodies
-
Koyama, Y.; Barrett, T.; Hama, Y.; Ravizzini, G.; Choyke, P.L.; Kobayashi, H., In vivo molecular imaging to diagnose and subtype tumors through receptor-targeted optically labeled monoclonal antibodies. Neoplasia, 2007, 9, 1021-1029.
-
(2007)
Neoplasia
, vol.9
, pp. 1021-1029
-
-
Koyama, Y.1
Barrett, T.2
Hama, Y.3
Ravizzini, G.4
Choyke, P.L.5
Kobayashi, H.6
-
43
-
-
60549118187
-
In vivo molecular imaging of cancer with a quenching near-infrared fluorescent probe using conjugates of monoclonal antibodies and indocyanine green
-
Ogawa, M.; Kosaka, N.; Choyke, P.L.; Kobayashi, H., In vivo molecular imaging of cancer with a quenching near-infrared fluorescent probe using conjugates of monoclonal antibodies and indocyanine green. Cancer Res, 2009, 69, 1268-1272.
-
(2009)
Cancer Res
, vol.69
, pp. 1268-1272
-
-
Ogawa, M.1
Kosaka, N.2
Choyke, P.L.3
Kobayashi, H.4
-
44
-
-
0028225314
-
Antibody-indocyanin conjugates for immunophotodetection of human squamous cell carcinoma in nude mice
-
Folli, S.; Westermann, P.; Braichotte, D.; Pelegrin, A.; Wagnieres, G.; van den Bergh, H.; Mach, J.P., Antibody-indocyanin conjugates for immunophotodetection of human squamous cell carcinoma in nude mice. Cancer Res, 1994, 54, 2643-2649.
-
(1994)
Cancer Res
, vol.54
, pp. 2643-2649
-
-
Folli, S.1
Westermann, P.2
Braichotte, D.3
Pelegrin, A.4
Wagnieres, G.5
Van Den Bergh, H.6
MacH, J.P.7
-
45
-
-
0028824432
-
Tumor labeling in-vivo using cyanine-conjugated monoclonal-antibodies
-
Ballou, B.; Fisher, G.W.; Waggoner, A.S.; Farkas, D.L.; Reiland, J.M.; Jaffe, R.; Mujumdar, R.B.; Mujumdar, S.R.; Hakala, T.R., Tumor Labeling in-Vivo Using Cyanine-Conjugated Monoclonal-Antibodies. Cancer Immunol Immun, 1995, 41, 257-263.
-
(1995)
Cancer Immunol Immun
, vol.41
, pp. 257-263
-
-
Ballou, B.1
Fisher, G.W.2
Waggoner, A.S.3
Farkas, D.L.4
Reiland, J.M.5
Jaffe, R.6
Mujumdar, R.B.7
Mujumdar, S.R.8
Hakala, T.R.9
-
46
-
-
78651462095
-
Cy5.5-labeled Affibody molecule for near-infrared fluorescent optical imaging of epidermal growth factor receptor positive tumors
-
Miao, Z.; Ren, G.; Liu, H.; Jiang, L.; Cheng, Z., Cy5.5-labeled Affibody molecule for near-infrared fluorescent optical imaging of epidermal growth factor receptor positive tumors. J Biomed Opt, 2010, 15, 036007.
-
(2010)
J Biomed Opt
, vol.15
, pp. 036007
-
-
Miao, Z.1
Ren, G.2
Liu, H.3
Jiang, L.4
Cheng, Z.5
-
47
-
-
76749085636
-
In vivo imaging of xenograft tumors using an epidermal growth factor receptor-specific affibody molecule labeled with a near-infrared fluorophore
-
Gong, H.; Kovar, J.; Little, G.; Chen, H.; Olive, D.M., In vivo imaging of xenograft tumors using an epidermal growth factor receptor-specific affibody molecule labeled with a near-infrared fluorophore. Neoplasia, 2010, 12, 139-149.
-
(2010)
Neoplasia
, vol.12
, pp. 139-149
-
-
Gong, H.1
Kovar, J.2
Little, G.3
Chen, H.4
Olive, D.M.5
-
48
-
-
77956492439
-
Quantitative analysis of Her2 receptor expression in vivo by nearinfrared optical imaging
-
Chernomordik, V.; Hassan, M.; Lee, S.B.; Zielinski, R.; Gandjbakhche, A.; Capala, J., Quantitative analysis of Her2 receptor expression in vivo by nearinfrared optical imaging. Mol Imaging, 2010, 9, 192-200.
-
(2010)
Mol Imaging
, vol.9
, pp. 192-200
-
-
Chernomordik, V.1
Hassan, M.2
Lee, S.B.3
Zielinski, R.4
Gandjbakhche, A.5
Capala, J.6
-
49
-
-
34548567115
-
Dual-labeled trastuzumab-based imaging agent for the detection of human epidermal growth factor receptor 2 overexpression in breast cancer
-
Sampath, L.; Kwon, S.; Ke, S.; Wang, W.; Schiff, R.; Mawad, M.E.; Sevick-Muraca, E.M., Dual-labeled trastuzumab-based imaging agent for the detection of human epidermal growth factor receptor 2 overexpression in breast cancer. J Nucl Med, 2007, 48, 1501-1510.
-
(2007)
J Nucl Med
, vol.48
, pp. 1501-1510
-
-
Sampath, L.1
Kwon, S.2
Ke, S.3
Wang, W.4
Schiff, R.5
Mawad, M.E.6
Sevick-Muraca, E.M.7
-
50
-
-
61849160330
-
Tumor-specific detection of an optically targeted antibody combined with a quencherconjugated neutravidin "quencher-chaser" a dual "quench and chase" strategy to improve target to nontarget ratios for molecular imaging of cancer
-
Ogawa, M.; Kosaka, N.; Choyke, P.L.; Kobayashi, H., Tumor-specific detection of an optically targeted antibody combined with a quencherconjugated neutravidin "quencher-chaser": a dual "quench and chase" strategy to improve target to nontarget ratios for molecular imaging of cancer. Bioconjug Chem, 2009, 20, 147-154.
-
(2009)
Bioconjug Chem
, vol.20
, pp. 147-154
-
-
Ogawa, M.1
Kosaka, N.2
Choyke, P.L.3
Kobayashi, H.4
-
51
-
-
36749036711
-
In vivo diagnosis of epidermal growth factor receptor expression using molecular imaging with a cocktail of optically labeled monoclonal antibodies
-
Barrett, T.; Koyama, Y.; Hama, Y.; Ravizzini, G.; Shin, I.S.; Jang, B.S.; Paik, C.H.; Urano, Y.; Choyke, P.L.; Kobayashi, H., In vivo diagnosis of epidermal growth factor receptor expression using molecular imaging with a cocktail of optically labeled monoclonal antibodies. Clin Cancer Res, 2007, 13, 6639-6648.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 6639-6648
-
-
Barrett, T.1
Koyama, Y.2
Hama, Y.3
Ravizzini, G.4
Shin, I.S.5
Jang, B.S.6
Paik, C.H.7
Urano, Y.8
Choyke, P.L.9
Kobayashi, H.10
-
52
-
-
79951590463
-
Target-cancer-cell-specific activatable fluorescence imaging probes: Rational design and in vivo applications
-
Kobayashi, H.; Choyke, P.L., Target-cancer-cell-specific activatable fluorescence imaging probes: rational design and in vivo applications. Acc Chem Res, 2011, 44, 83-90.
-
(2011)
Acc Chem Res
, vol.44
, pp. 83-90
-
-
Kobayashi, H.1
Choyke, P.L.2
-
53
-
-
67650787319
-
H-type dimer formation of fluorophores: A mechanism for activatable, in vivo optical molecular imaging
-
Ogawa, M.; Kosaka, N.; Choyke, P.L.; Kobayashi, H., H-type dimer formation of fluorophores: a mechanism for activatable, in vivo optical molecular imaging. ACS Chem Biol, 2009, 4, 535-546.
-
(2009)
ACS Chem Biol
, vol.4
, pp. 535-546
-
-
Ogawa, M.1
Kosaka, N.2
Choyke, P.L.3
Kobayashi, H.4
-
54
-
-
34248575488
-
Activatable fluorescent molecular imaging of peritoneal metastases following pretargeting with a biotinylated monoclonal antibody
-
Hama, Y.; Urano, Y.; Koyama, Y.; Choyke, P.L.; Kobayashi, H., Activatable fluorescent molecular imaging of peritoneal metastases following pretargeting with a biotinylated monoclonal antibody. Cancer Res, 2007, 67, 3809-3817.
-
(2007)
Cancer Res
, vol.67
, pp. 3809-3817
-
-
Hama, Y.1
Urano, Y.2
Koyama, Y.3
Choyke, P.L.4
Kobayashi, H.5
-
55
-
-
58149357048
-
Selective molecular imaging of viable cancer cells with pH-activatable fluorescence probes
-
Urano, Y.; Asanuma, D.; Hama, Y.; Koyama, Y.; Barrett, T.; Kamiya, M.; Nagano, T.; Watanabe, T.; Hasegawa, A.; Choyke, P.L.; Kobayashi, H., Selective molecular imaging of viable cancer cells with pH-activatable fluorescence probes. Nat Med, 2009, 15, 104-109.
-
(2009)
Nat Med
, vol.15
, pp. 104-109
-
-
Urano, Y.1
Asanuma, D.2
Hama, Y.3
Koyama, Y.4
Barrett, T.5
Kamiya, M.6
Nagano, T.7
Watanabe, T.8
Hasegawa, A.9
Choyke, P.L.10
Kobayashi, H.11
-
56
-
-
77952415077
-
High sensitivity detection of cancer in vivo using a dualcontrolled activation fluorescent imaging probe based on H-dimer formation and pH activation
-
Ogawa, M.; Kosaka, N.; Regino, C.A.; Mitsunaga, M.; Choyke, P.L.; Kobayashi, H., High sensitivity detection of cancer in vivo using a dualcontrolled activation fluorescent imaging probe based on H-dimer formation and pH activation. Mol Biosyst, 2010, 6, 888-893.
-
(2010)
Mol Biosyst
, vol.6
, pp. 888-893
-
-
Ogawa, M.1
Kosaka, N.2
Regino, C.A.3
Mitsunaga, M.4
Choyke, P.L.5
Kobayashi, H.6
-
57
-
-
58149518584
-
In vivo targetspecific activatable near-infrared optical labeling of humanized monoclonal antibodies
-
Ogawa, M.; Regino, C.A.; Choyke, P.L.; Kobayashi, H., In vivo targetspecific activatable near-infrared optical labeling of humanized monoclonal antibodies. Mol Cancer Ther, 2009, 8, 232-239.
-
(2009)
Mol Cancer Ther
, vol.8
, pp. 232-239
-
-
Ogawa, M.1
Regino, C.A.2
Choyke, P.L.3
Kobayashi, H.4
-
58
-
-
77949583101
-
Semiquantitative assessment of the microdistribution of fluorescencelabeled monoclonal antibody in small peritoneal disseminations of ovarian cancer
-
Kosaka, N.; Ogawa, M.; Paik, D.S.; Paik, C.H.; Choyke, P.L.; Kobayashi, H., Semiquantitative assessment of the microdistribution of fluorescencelabeled monoclonal antibody in small peritoneal disseminations of ovarian cancer. Cancer Sci, 2010, 101, 820-825.
-
(2010)
Cancer Sci
, vol.101
, pp. 820-825
-
-
Kosaka, N.1
Ogawa, M.2
Paik, D.S.3
Paik, C.H.4
Choyke, P.L.5
Kobayashi, H.6
-
59
-
-
71249087175
-
Dual-modality molecular imaging using antibodies labeled with activatable fluorescence and a radionuclide for specific and quantitative targeted cancer detection
-
Ogawa, M.; Regino, C.A.; Seidel, J.; Green, M.V.; Xi, W.; Williams, M.; Kosaka, N.; Choyke, P.L.; Kobayashi, H., Dual-modality molecular imaging using antibodies labeled with activatable fluorescence and a radionuclide for specific and quantitative targeted cancer detection. Bioconjug Chem, 2009, 20, 2177-2184.
-
(2009)
Bioconjug Chem
, vol.20
, pp. 2177-2184
-
-
Ogawa, M.1
Regino, C.A.2
Seidel, J.3
Green, M.V.4
Xi, W.5
Williams, M.6
Kosaka, N.7
Choyke, P.L.8
Kobayashi, H.9
-
60
-
-
51549094831
-
Human breast cancer tumor models: Molecular imaging of drug susceptibility and dosing during HER2/neu-targeted therapy
-
Gee, M.S.; Upadhyay, R.; Bergquist, H.; Alencar, H.; Reynolds, F.; Maricevich, M.; Weissleder, R.; Josephson, L.; Mahmood, U., Human breast cancer tumor models: molecular imaging of drug susceptibility and dosing during HER2/neu-targeted therapy. Radiology, 2008, 248, 925-935.
-
(2008)
Radiology
, vol.248
, pp. 925-935
-
-
Gee, M.S.1
Upadhyay, R.2
Bergquist, H.3
Alencar, H.4
Reynolds, F.5
Maricevich, M.6
Weissleder, R.7
Josephson, L.8
Mahmood, U.9
-
61
-
-
46249109580
-
Fluorescent labeled anti-EGFR antibody for identification of regional and distant metastasis in a preclinical xenograft model
-
Gleysteen, J.P.; Newman, J.R.; Chhieng, D.; Frost, A.; Zinn, K.R.; Rosenthal, E.L., Fluorescent labeled anti-EGFR antibody for identification of regional and distant metastasis in a preclinical xenograft model. Head Neck, 2008, 30, 782-789.
-
(2008)
Head Neck
, vol.30
, pp. 782-789
-
-
Gleysteen, J.P.1
Newman, J.R.2
Chhieng, D.3
Frost, A.4
Zinn, K.R.5
Rosenthal, E.L.6
-
62
-
-
65349110396
-
Multi-targeted multi-color in vivo optical imaging in a model of disseminated peritoneal ovarian cancer
-
Kosaka, N.; Ogawa, M.; Longmire, M.R.; Choyke, P.L.; Kobayashi, H., Multi-targeted multi-color in vivo optical imaging in a model of disseminated peritoneal ovarian cancer. J Biomed Opt, 2009, 14, 014023.
-
(2009)
J Biomed Opt
, vol.14
, pp. 014023
-
-
Kosaka, N.1
Ogawa, M.2
Longmire, M.R.3
Choyke, P.L.4
Kobayashi, H.5
-
63
-
-
64649090835
-
Fluorophore-quencher based activatable targeted optical probes for detecting in vivo cancer metastases
-
Ogawa, M.; Kosaka, N.; Longmire, M.R.; Urano, Y.; Choyke, P.L.; Kobayashi, H., Fluorophore-quencher based activatable targeted optical probes for detecting in vivo cancer metastases. Mol Pharm, 2009, 6, 386-395.
-
(2009)
Mol Pharm
, vol.6
, pp. 386-395
-
-
Ogawa, M.1
Kosaka, N.2
Longmire, M.R.3
Urano, Y.4
Choyke, P.L.5
Kobayashi, H.6
-
64
-
-
0242268462
-
The homodimer of prostatespecific membrane antigen is a functional target for cancer therapy
-
Schulke, N.; Varlamova, O.A.; Donovan, G.P.; Ma, D.; Gardner, J.P.; Morrissey, D.M.; Arrigale, R.R.; Zhan, C.; Chodera, A.J.; Surowitz, K.G.; Maddon, P.J.; Heston, W.D.; Olson, W.C., The homodimer of prostatespecific membrane antigen is a functional target for cancer therapy. Proc Natl Acad Sci U S A, 2003, 100, 12590-12595.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 12590-12595
-
-
Schulke, N.1
Varlamova, O.A.2
Donovan, G.P.3
Ma, D.4
Gardner, J.P.5
Morrissey, D.M.6
Arrigale, R.R.7
Zhan, C.8
Chodera, A.J.9
Surowitz, K.G.10
Maddon, P.J.11
Heston, W.D.12
Olson, W.C.13
-
65
-
-
80051777429
-
Targeted activatable, in vivo fluorescence imaging of prostate-specific membrane antigen (PSMA) positive tumors using the quenched humanized J591 antibody-indocyanine green (ICG) conjugate
-
Nakajima, T.; Mitsunaga, M.; Bander, N.H.; Heston, W.D.; Choyke, P.L.; Kobayashi, H., Targeted, Activatable, In Vivo Fluorescence Imaging of Prostate-Specific Membrane Antigen (PSMA) Positive Tumors Using the Quenched Humanized J591 Antibody-Indocyanine Green (ICG) Conjugate. Bioconjug Chem, 2011.
-
(2011)
Bioconjug Chem
-
-
Nakajima, T.1
Mitsunaga, M.2
Bander, N.H.3
Heston, W.D.4
Choyke, P.L.5
Kobayashi, H.6
|