Fluorophore-quencher based activatable targeted optical probes for detecting in vivo cancer metastases

Molecular Pharmaceutics

Volumn 6, Issue 2, 2009, Pages 386-395

  Ogawa, Mikako ^a   Kosaka, Nobuyuki ^a   Longmire, Michelle R ^a   Urano, Yasuteru ^b   Choyke, Peter L ^a   Kobayashi, Hisataka ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

Activatable; Cancer; FRET; Molecular imaging; Photoquencher

Indexed keywords

AVIDIN; AVIDIN TETRAMETHYL 6 CARBOXYRHODAMINE QSY 7 CONJUGATE; DYE; FLUORESCENT DYE; FLUOROPHORE; QSY 7; TETRAMETHYL 6 CARBOXYRHODAMINE; TETRAMETHYLRHODAMINE; TRASTUZUMAB; TRASTUZUMAB TETRAMETHYL 6 CARBOXYRHODAMINE QSY 7 CONJUGATE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CELL CULTURE; CANCER DIAGNOSIS; CANCER MODEL; CONTROLLED STUDY; DRUG CONJUGATION; DRUG FORMULATION; DRUG SYNTHESIS; DRUG TARGETING; FEMALE; FLUORESCENCE IMAGING; FLUORESCENCE RESONANCE ENERGY TRANSFER; FLUOROPHORE QUENCHER SYSTEM; IN VIVO STUDY; INTERNALIZATION; METASTASIS; MOLECULAR IMAGING; MOLECULAR PROBE; MOUSE; NONHUMAN; PHOTOCHEMICAL QUENCHING; PRIORITY JOURNAL;

ANIMALS; ANTIBODIES, MONOCLONAL; AVIDIN; BALB 3T3 CELLS; FEMALE; FLUORESCENT DYES; GREEN FLUORESCENT PROTEINS; HUMANS; LUNG NEOPLASMS; MICE; MICE, NUDE; MICROSCOPY, FLUORESCENCE; NIH 3T3 CELLS; RECEPTOR, ERBB-2; RECEPTORS, CELL SURFACE; RHODAMINES; TRANSFECTION;

EID: 64649090835     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp800115t     Document Type: Article

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