Hypoadiponectinemia and its association with liver fibrosis in morbidly obese patients

Obesity Surgery

Volumn 20, Issue 10, 2010, Pages 1400-1407

  Nazal, Leyla ^a   Riquelme, Arnoldo ^a   Solís, Nancy ^a   Pizarro, Margarita ^a   Escalona, Alex ^a   Burotto, Mauricio ^a   Méndez, Juan Ignacio ^a   Saint Jean, Catalina ^a   Concha, María José ^a   Giovanni, Stefano ^a   Awruch, Diego ^a   Morales, Arturo ^a   Baudrand, Rene ^a   Carrasco, Gonzalo ^a   Domínguez, María Angélica ^a   Padilla, Oslando ^a   Espinoza, Manuel ^a   Miquel, Juan Francisco ^a   Nervi, Flavio ^a   Arrese, Marco ^a  

^a PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE   (Chile)

Author keywords

Adipokines; Fatty liver; Hepatic steatosis; Steatohepatitis

Indexed keywords

ADIPONECTIN; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; C REACTIVE PROTEIN; GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; LEPTIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL;

ADULT; AGED; ANTHROPOMETRY; ARTICLE; BARIATRIC SURGERY; BODY MASS; CASE CONTROL STUDY; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE SEVERITY; FEMALE; HISTOPATHOLOGY; HOMEOSTASIS; HUMAN; HUMAN TISSUE; HYPERTENSION; HYPOADIPONECTINEMIA; INSULIN RESISTANCE; LIVER BIOPSY; LIVER FIBROSIS; LIVER HISTOLOGY; MAJOR CLINICAL STUDY; MALE; MORBID OBESITY; NON INSULIN DEPENDENT DIABETES MELLITUS; NONALCOHOLIC FATTY LIVER; PRIORITY JOURNAL; PROSPECTIVE STUDY; PROTEIN BLOOD LEVEL; PROTEIN DEFECT; RECEIVER OPERATING CHARACTERISTIC; SEX DIFFERENCE;

ADIPONECTIN; ADOLESCENT; ADULT; AGED; CASE-CONTROL STUDIES; COMORBIDITY; FATTY LIVER; FEMALE; HUMANS; LIVER; LIVER CIRRHOSIS; MALE; MIDDLE AGED; OBESITY, MORBID; ROC CURVE; YOUNG ADULT;

EID: 77956958619     PISSN: 09608923     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11695-009-0051-0     Document Type: Article

References (50)

1. P Angulo 2002 Nonalcoholic fatty liver disease N Engl J Med 346 1221 1231 1:CAS:528:DC%2BD38XivVOmsrY%3D 10.1056/NEJMra011775 11961152
2. P Angulo 2007 GI epidemiology: nonalcoholic fatty liver disease Aliment Pharmacol Ther 25 883 889 1:STN:280:DC%2BD2s3gtVyrtA%3D%3D 10.1111/j.1365-2036. 2007.03246.x 17402991
3. A Riquelme M Arrese A Soza, et al. 2009 Non-alcoholic fatty liver disease and its association with obesity, insulin resistance and increased serum levels of C-reactive protein in Hispanics Liver Int 29 82 88 1:CAS:528: DC%2BD1MXhvVGmtLs%3D 10.1111/j.1478-3231.2008.01823.x 18647235
4. EM Brunt 2007 Pathology of fatty liver disease Mod Pathol 20 Suppl 1 S40 S48 1:CAS:528:DC%2BD2sXkvFKit7k%3D 10.1038/modpathol.3800680 17486051
5. CA Matteoni ZM Younossi T Gramlich, et al. 1999 Nonalcoholic fatty liver disease: a spectrum of clinical and pathological severity Gastroenterology 116 1413 1419 1:STN:280:DyaK1M3nvVamtw%3D%3D 10.1016/S0016-5085(99)70506-8 10348825
6. MR Teli OF James AD Burt, et al. 1995 The natural history of nonalcoholic fatty liver: a follow-up study Hepatology 22 1714 1719 1:STN:280: DyaK28%2FovVyhtQ%3D%3D 10.1002/hep.1840220616 7489979
7. GP Aithal JA Thomas PV Kaye, et al. 2008 Randomized, placebo-controlled trial of pioglitazone in nondiabetic subjects with nonalcoholic steatohepatitis Gastroenterology 135 1176 1184 1:CAS:528:DC%2BD1cXht12lurrN 10.1053/j.gastro. 2008.06.047 18718471
8. NM de Alwis CP Day 2008 Non-alcoholic fatty liver disease: the mist gradually clears J Hepatol 48 Suppl 1 S104 S112 18304679
9. E Bugianesi N Leone E Vanni, et al. 2002 Expanding the natural history of nonalcoholic steatohepatitis: from cryptogenic cirrhosis to hepatocellular carcinoma Gastroenterology 123 134 140 10.1053/gast.2002.34168 12105842
10. GC Farrell CZ Larter 2006 Nonalcoholic fatty liver disease: from steatosis to cirrhosis Hepatology 43 S99 S112 1:CAS:528:DC%2BD28XhvVSktLo%3D 10.1002/hep.20973 16447287
11. JP Ong ZM Younossi 2007 Epidemiology and natural history of NAFLD and NASH Clin Liver Dis 11 1 16 10.1016/j.cld.2007.02.009 17544968 vii
12. F Marra A Gastaldelli G Svegliati Baroni 2008 Molecular basis and mechanisms of progression of non-alcoholic steatohepatitis Trends Mol Med 14 72 81 1:CAS:528:DC%2BD1cXitVGltL0%3D 10.1016/j.molmed.2007.12.003 18218340
13. M Arrese 2009 Burning hepatic fat: therapeutic potential for liver-specific thyromimetics in the treatment of nonalcoholic fatty liver disease Hepatology 49 348 351 10.1002/hep.22783 19177580
14. G Perlemuter A Bigorgne AM Cassard-Doulcier, et al. 2007 Nonalcoholic fatty liver disease: from pathogenesis to patient care Nat Clin Pract Endocrinol Metab 3 458 469 1:CAS:528:DC%2BD2sXlsFGrsrc%3D 10.1038/ncpendmet0505 17515890
15. P Arner 2005 Insulin resistance in type 2 diabetes-role of the adipokines Curr Mol Med 5 333 339 1:CAS:528:DC%2BD2MXkt1Cnt7w%3D 10.2174/1566524053766022 15892652
16. H Tilg GS Hotamisligil 2006 Nonalcoholic fatty liver disease: cytokine-adipokine interplay and regulation of insulin resistance Gastroenterology 131 934 945 1:CAS:528:DC%2BD28XhtVKrurbP 10.1053/j.gastro.2006. 05.054 16952562
17. C Carter-Kent NN Zein AE Feldstein 2008 Cytokines in the pathogenesis of fatty liver and disease progression to steatohepatitis: implications for treatment Am J Gastroenterol 103 1036 1042 1:CAS:528:DC%2BD1cXls1Cqtr4%3D 10.1111/j.1572-0241.2007.01709.x 18177455
18. M Guerre-Millo 2008 Adiponectin: an update Diabetes Metab 34 12 18 1:CAS:528:DC%2BD1cXkslOksr0%3D 18069030
19. J Wang J Brymora J George 2008 Roles of adipokines in liver injury and fibrosis Expert Rev Gastroenterol Hepatol 2 47 57 10.1586/17474124.2.1.47 19072370
20. JM Hui A Hodge GC Farrell, et al. 2004 Beyond insulin resistance in NASH: TNF-alpha or adiponectin? Hepatology 40 46 54 1:CAS:528:DC%2BD2cXmtlSgtLY%3D 10.1002/hep.20280 15239085
21. A Lopez-Bermejo P Botas T Funahashi, et al. 2004 Adiponectin, hepatocellular dysfunction and insulin sensitivity Clin Endocrinol (Oxf) 60 256 263 1:CAS:528:DC%2BD2cXhvF2lurg%3D 10.1046/j.1365-2265.2004.01977.x
22. S Kaser A Moschen A Cayon, et al. 2005 Adiponectin and its receptors in non-alcoholic steatohepatitis Gut 54 117 121 1:CAS:528:DC%2BD2MXntFOqtQ%3D%3D 10.1136/gut.2003.037010 15591515
23. KV Kowdley DS Pratt 2005 Adiponectin-tipping the scales from NAFLD to NASH? Gastroenterology 128 511 513 10.1053/j.gastro.2004.10.047 15685567 (author reply 513)
24. M Lemoine V Ratziu M Kim, et al. 2009 Serum adipokine levels predictive of liver injury in non-alcoholic fatty liver disease Liver Int 29 1431 1438 1:CAS:528:DC%2BD1MXht1GntL3E 10.1111/j.1478-3231.2009.02022.x 19422483
25. M Arrese A Riquelme 2009 The value of serum adipokine measurement in non-alcoholic fatty liver disease Liver Int 29 9 1291 1293 10.1111/j.1478-3231. 2009.02119.x 19744070
26. E Bugianesi U Pagotto R Manini, et al. 2005 Plasma adiponectin in nonalcoholic fatty liver is related to hepatic insulin resistance and hepatic fat content, not to liver disease severity J Clin Endocrinol Metab 90 3498 3504 1:CAS:528:DC%2BD2MXkvFCltLs%3D 10.1210/jc.2004-2240 15797948
27. NA Palekar R Naus SP Larson, et al. 2006 Clinical model for distinguishing nonalcoholic steatohepatitis from simple steatosis in patients with nonalcoholic fatty liver disease Liver Int 26 151 156 10.1111/j.1478-3231. 2005.01209.x 16448452
28. C Boza A Riquelme L Ibanez, et al. 2005 Predictors of nonalcoholic steatohepatitis (NASH) in obese patients undergoing gastric bypass Obes Surg 15 1148 1153 10.1381/0960892055002347 16197788
29. M Machado P Marques-Vidal H Cortez-Pinto 2006 Hepatic histology in obese patients undergoing bariatric surgery J Hepatol 45 600 606 10.1016/j.jhep.2006. 06.013 16899321
30. JF Miquel C Covarrubias L Villaroel, et al. 1998 Genetic epidemiology of cholesterol cholelithiasis among Chilean Hispanics, Amerindians, and Maoris Gastroenterology 115 937 946 1:STN:280:DyaK1cvis1egtw%3D%3D 10.1016/S0016- 5085(98)70266-5 9753497
31. CE Ruhl JE Everhart 2004 Epidemiology of nonalcoholic fatty liver Clin Liver Dis 8 501 519 10.1016/j.cld.2004.04.008 15331060 vii
32. P Charatcharoenwitthaya KD Lindor 2007 Role of radiologic modalities in the management of non-alcoholic steatohepatitis Clin Liver Dis 11 37 54 10.1016/j.cld.2007.02.014 17544971 viii
33. P Mishra ZM Younossi 2007 Abdominal ultrasound for diagnosis of nonalcoholic fatty liver disease (NAFLD) Am J Gastroenterol 102 2716 2717 10.1111/j.1572-0241.2007.01520.x 18042105
34. E Bonora G Targher M Alberiche, et al. 2000 Homeostasis model assessment closely mirrors the glucose clamp technique in the assessment of insulin sensitivity: studies in subjects with various degrees of glucose tolerance and insulin sensitivity Diabetes Care 23 57 63 1:STN:280:DC%2BD3czpsVyisA%3D%3D 10.2337/diacare.23.1.57 10857969
35. AM Acosta M Escalona A Maiz, et al. 2002 Determination of the insulin resistance index by the homeostasis model assessment in a population of Metropolitan Region in Chile Rev Med Chil 130 1227 1231 1:CAS:528: DC%2BD3sXnvVaqsg%3D%3D 12587504
36. SM Grundy JI Cleeman SR Daniels, et al. 2005 Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement Circulation 112 2735 2752 10.1161/CIRCULATIONAHA.105.169404 16157765
37. CE Ruhl JE Everhart 2003 Determinants of the association of overweight with elevated serum alanine aminotransferase activity in the United States Gastroenterology 124 71 79 1:CAS:528:DC%2BD3sXot1antw%3D%3D 10.1053/gast.2003. 50004 12512031
38. American Diabetes Association 2007 Standards of medical care in diabetes-2007 Diabetes Care 30 Suppl 1 S4 S41 10.2337/dc07-S004
39. Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults 2001 Executive Summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) JAMA 285 2486 2497 10.1001/jama.285.19.2486
40. Gastrointestinal surgery for severe obesity: National Institutes of Health Consensus Development Conference Statement. Am J Clin Nutr 1992;55:615S-9S
41. DE Kleiner EM Brunt M Van Natta, et al. 2005 Design and validation of a histological scoring system for nonalcoholic fatty liver disease Hepatology 41 1313 1321 10.1002/hep.20701 15915461
42. A Xu Y Wang H Keshaw, et al. 2003 The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice J Clin Invest 112 91 100 1:CAS:528:DC%2BD3sXlt1Krt7c%3D 12840063
43. MH Jarrar A Baranova R Collantes, et al. 2008 Adipokines and cytokines in non-alcoholic fatty liver disease Aliment Pharmacol Ther 27 412 421 1:CAS:528:DC%2BD1cXjt1Wntb8%3D 10.1111/j.1365-2036.2007.03586.x 18081738
44. R Vuppalanchi S Marri D Kolwankar, et al. 2005 Is adiponectin involved in the pathogenesis of nonalcoholic steatohepatitis? A preliminary human study J Clin Gastroenterol 39 237 242 10.1097/01.mcg.0000152747.79773.2f 15718867
45. S Savvidou P Hytiroglou H Orfanou-Koumerkeridou 2009 Low serum adiponectin levels are predictive of advanced hepatic fibrosis in patients with NAFLD J Clin Gastroenterol 43 765 772 1:CAS:528:DC%2BD1MXhtVWkur%2FO 10.1097/MCG.0b013e31819e9048 19525862
46. ZM Younossi M Jarrar C Nugent, et al. 2008 A novel diagnostic biomarker panel for obesity-related nonalcoholic steatohepatitis (NASH) Obes Surg 18 1430 1437 10.1007/s11695-008-9506-y 18500507
47. LE Munoz P Cordero L Torres, et al. 2009 Adipokines in a group of Mexican patients with nonalcoholic steatohepatitis Ann Hepatol 8 123 128 19502655
48. G Targher L Bertolini S Rodella, et al. 2006 Associations between liver histology and cortisol secretion in subjects with nonalcoholic fatty liver disease Clin Endocrinol (Oxf) 64 337 341 1:CAS:528:DC%2BD28XjsFejs78%3D 10.1111/j.1365-2265.2006.02466.x
49. JF Carroll AL Chiapa M Rodriquez, et al. 2008 Visceral fat, waist circumference, and BMI: impact of race/ethnicity Obesity (Silver Spring) 16 600 607 10.1038/oby.2007.92
50. DK Richardson J Schneider MJ Fourcaudot, et al. 2006 Association between variants in the genes for adiponectin and its receptors with insulin resistance syndrome (IRS)-related phenotypes in Mexican Americans Diabetologia 49 2317 2328 1:CAS:528:DC%2BD28XptF2kurY%3D 10.1007/s00125-006-0384-3