Quinoline ring derivatives protect against aminoglycoside-induced hair cell death in the zebrafish lateral line

JARO - Journal of the Association for Research in Otolaryngology

Volumn 13, Issue 6, 2012, Pages 759-770

  Ou, Henry C ^a,b   Keating, Sarah ^a   Wu, Patricia ^a   Simon, Julian A ^c   Raible, David W ^a   Rubel, Edwin W ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b SEATTLE CHILDREN S HOSPITAL   (United States)

^c USA   (United States)

Author keywords

Hair cell protection; Quinoline ring; Zebrafish

Indexed keywords

AMODIAQUINE; AMSACRINE; CHLOROQUINE; CINCHONIDINE; CINCHONINE; GENTAMICIN; HISTAMINE; INDOLE; ISOQUINOLINE; MEFLOQUINE; NAPHTHALENE; NEOMYCIN; QUININE; QUINOLINE; QUINOLINE DERIVATIVE; TACRINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BACTERICIDAL ACTIVITY; CELL DEATH; CELL SURVIVAL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG STRUCTURE; DRUG UPTAKE; HAIR CELL; LATERAL LINE SYSTEM; LONG TERM EXPOSURE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; ZEBRA FISH;

AMINOGLYCOSIDES; ANIMALS; ANTI-BACTERIAL AGENTS; BACTERIA; CELL DEATH; DOSE-RESPONSE RELATIONSHIP, DRUG; GENTAMICINS; HAIR CELLS, AUDITORY; NEOMYCIN; QUINOLINES; ZEBRAFISH;

EID: 84870430202     PISSN: 15253961     EISSN: 14387573     Source Type: Journal    
DOI: 10.1007/s10162-012-0353-0     Document Type: Article

References (27)

1. ALHARAZNEH A, LUK L, HUTH M, MONFARED A, STEYGER PS, CHENG AG, RICCI AJ (2011) Functional hair cell mechanotransducer channels are required for aminoglycoside ototoxicity. PLoS One 6(7): e22347
2. CAMPBELL KC, MEECH RP, KLEMENS JJ, GERBERI MT, DYRSTAD SS, LARSEN DL, MITCHELL DL, EL-AZIZI M, VERHULST SJ, HUGHES LF (2007) Prevention of noise- and drug-induced hearing loss with Dmethionine. Hear Res 226:92-103
3. CUMMING P, REINER PB, VINCENT SR (1990) Inhibition of rat brain histamine-N-methyltransferase by 9-amino-1,2,3,4-tetrahydroacridine (THA). Biochem Pharmacol 40:1345-1350
4. DETSI A, BOULOUMBASI D, PROUSIS KC, KOUFAKI M, ATHANASELLIS G, MELAGRAKI G, AFANTITIS A, IGGLESSI-MARKOPOULOU O, KONTOGIORGIS C, HADJIPAVLOU-LITINA DJ (2007) Design and synthesis of novel quinolinone-3-aminoamides and their alpha-lipoic acid adducts as antioxidant and anti-inflammatory agents. J Med Chem 50 (10):2450-2458
5. DRUKARCH B, KITS KS, VAN DER MEER EG, LODDER JC, STOOF JC (1987) 9-Amino-1,2,3,4-tetrahydroacridine (THA), an alleged drug for the treatment of Alzheimer's disease, inhibits acetylcholinesterase activity and slow outward K+ current. Eur J Pharmacol 141:153-157
6. FARRIS HE, LEBLANC CL, GOSWAMI J, RICCI AJ (2004) Probing the pore of the auditory hair cell mechanotransducer channel in turtle. J Physiol 558:769-792
7. GHINET A, FARCE A, OUDIR S, POMMERY J, VAMECQ J, HENICHART JP, RIGO B, GAUTRET P (2012) Antioxidant activity of new benzo[de] quinolines and lactams: 2D-quantitative structure-activity relationships. Med Chem 8(5):942-946
8. HARLE DG, BALDO BA (1988) Structural features of potent inhibitors of rat kidney histamine N-methyltransferase. Biochem Pharmacol 37:385-388
9. HORTON JR, SAWADA K, NISHIBORI M, CHENG X (2005) Structural basis for inhibition of histamine N-methyltransferase by diverse drugs. J Mol Biol 353:334-344
10. LIN Y, DEVIN A, RODRIGUEZ Y, LIU ZG (1999) Cleavage of the death domain kinase RIP by caspase-8 prompts TNF-induced apoptosis. Genes Dev 13:2514-2526
11. MATSUI JI, OGILVIE JM, WARCHOL ME (2002) Inhibition of caspases prevents ototoxic and ongoing hair cell death. J Neurosci 22:1218-1227
12. NAIK HR, NAIK HS, NAIK TR, NAIKA HR, GOUTHAMCHANDRA K, MAHMOOD R, AHAMED BM (2009) Synthesis of novel benzo[h] quinolines: wound healing, antibacterial, DNA binding and in vitro antioxidant activity. Eur J Med Chem 44(3):981-989
13. OU HC, CUNNINGHAM LL, FRANCIS SP, BRANDON CS, SIMON JA, RAIBLE DW, RUBEL EW (2009) Identification of FDA-approved drugs and bioactives that protect hair cells in the zebrafish (Danio rerio) lateral line and mouse (Mus musculus) utricle. J Assoc Res Otolaryngol 10:191-203
14. OWENS KN, SANTOS F, ROBERTS B, LINBO T, COFFIN AB, KNISELY AJ, SIMON JA, RUBEL EW, RAIBLE DW (2008) Identification of genetic and chemical modulators of zebrafish mechanosensory hair cell death. PLoS Genet 4:e1000020
15. OWENS KN, COFFIN AB, HONG LS, BENNETT KO, RUBEL EW, RAIBLE DW (2009) Response of mechanosensory hair cells of the zebrafish lateral line to aminoglycosides reveals distinct death pathways. Hear Res 253(1-2):32-41
16. PEARCE BD, POTTER LT (1988) Effects of tetrahydroaminoacridine on M1 and M2 muscarine receptors. Neurosci Lett 88:281-285
17. RAIBLE DW, KRUSE GJ (2000) Organization of the lateral line system in embryonic zebrafish. J Comp Neurol 421:189-198
18. ROLAND PS, STEWART MG, HANNLEY M, FRIEDMAN R, MANOLIDIS S, MATZ G, RYBAK L, WEBER P, OWENS F (2004) Consensus panel on role of potentially ototoxic antibiotics for topical middle ear use: Introduction, methodology, and recommendations. Otolaryngol Head Neck Surg 130:S51-S56
19. SCHMITT NC, RUBEL EW, NATHANSON NM (2009) Cisplatin-induced hair cell death requires STAT1 and is attenuated by epigallocatechine gallate. J Neurosci 29(12):3843-3851
20. SHA SH, QIU JH, SCHACHT J (2006) Aspirin to prevent gentamicininduced hearing loss. N Engl J Med 354:1856-1857
21. STEYGER PS, PETERS SL, REHLING J, HORDICHOK A, DAI CF (2003) Uptake of gentamicin by bullfrog saccular hair cells in vitro. J Assoc Res Otolaryngol 4(4):565-578
22. VANDENABEELE P, VANDEN BERGHE T, FESTJENS N (2006) Caspase inhibitors promote alternative cell death pathways. Sci STKE 2006:pe44
23. WANG J, VAN DE WATER TR, BONNY C, DE RIBAUPIERRE F, PUEL JL, ZINE A (2003) A peptide inhibitor of c-Jun N-terminal kinase protects against both aminoglycoside and acoustic trauma-induced auditory hair cell death and hearing loss. J Neurosci 23:8596-8607
24. WANG J, LADRECH S, PUJOL R, BRABET P, VAN DE WATER TR, PUEL JL (2004) Caspase inhibitors, but not c-Jun NH2-terminal kinase inhibitor treatment, prevent cisplatin-induced hearing loss. Cancer Res 64:9217-9224
25. WIKLER M (2006) Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically. Clinical and Laboratory Standards Institute, Wayne, pp 1-64
26. WIKLER M (2007) Performance standards for antimicrobial susceptibility testing. Clinical and Laboratory Standards Institute, Wayne, pp 1-182
27. YU L, ALVA A, SU H, DUTT P, FREUNDT E, WELSH S, BAEHRECKE EH, LENARDO MJ (2004) Regulation of an ATG7-beclin 1 program of autophagic cell death by caspase-8. Science 304:1500-1502