Protocatechuic acid alkyl esters: Hydrophobicity as a determinant factor for inhibition of NADPH oxidase

Current Medicinal Chemistry

Volumn 19, Issue 28, 2012, Pages 4885-4893

  De Faria, C M Q G ^a   Nazare A C ^a   Petronio M S ^a   Paracatu, L C ^a   Zeraik, M L ^a   Regasini, L O ^a   Silva, D H S ^a   Da Fonseca, L M ^a   Ximenes, V F ^a  

^a SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

Author keywords

Hydrogen peroxide; Hypochlorous acid; Myeloperoxidase; NADPH oxidase; Neutrophils; Oxidative burst; Peripheral blood mononuclear cells; Protocatechuic acid; Protocatechuic acid alkyl esters; Superoxide anion

Indexed keywords

1,1 DIPHENYL 2 PICRYLHYDRAZYL; BUTYL PROTOCATECHUATE; CARBON; DECYL PROTOCATECHUATE; HEPTYL PROTOCATECHUATE; HYPOCHLOROUS ACID; MYELOPEROXIDASE; OXYGEN; PEROXY RADICAL; PROTOCATECHUIC ACID; PROTOCATECHUIC ACID ALKYL ESTER; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE INHIBITOR; SUPEROXIDE; UNCLASSIFIED DRUG;

ANTIOXIDANT ACTIVITY; ANTIRADICAL ACTIVITY; ARTICLE; CHLORINATION; CHRONIC INFLAMMATION; CONTROLLED STUDY; DRUG ACTIVITY; DRUG DESIGN; DRUG POTENCY; ENZYME ACTIVITY; ENZYME INHIBITION; ESTERIFICATION; HUMAN; HUMAN CELL; HYDROPHOBICITY; LEUKOCYTE; OXIDATION REDUCTION POTENTIAL; PERIPHERAL BLOOD MONONUCLEAR CELL; SCAVENGING SYSTEM; SYNTHESIS;

ELECTROCHEMICAL TECHNIQUES; ESTERS; FREE RADICAL SCAVENGERS; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; HYDROXYBENZOATES; HYPOCHLOROUS ACID; KINETICS; LEUKOCYTES, MONONUCLEAR; NADPH OXIDASE; NEUTROPHILS; PEROXIDASE; SUPEROXIDES;

EID: 84870423567     PISSN: 09298673     EISSN: 1875533X     Source Type: Journal    
DOI: 10.2174/092986712803341557     Document Type: Article

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