Administration of rosmarinic acid reduces cardiopathology and blood pressure through inhibition of p22phox NADPH oxidase in fructose-fed hypertensive rats

Journal of Cardiovascular Pharmacology

Volumn 58, Issue 5, 2011, Pages 514-521

  Karthik, Dhanapalan ^a   Viswanathan, Periyasami ^a   Anuradha, Carani Venkatraman ^a  

^a ANNAMALAI UNIVERSITY   (India)

Author keywords

blood pressure; heart; insulin resistance; nicotinamide adenine dinucleotide phosphate reduced oxidase; rosmarinic acid

Indexed keywords

ANTIOXIDANT; ASPARTATE AMINOTRANSFERASE; CATALASE; CHOLESTEROL; CREATINE KINASE MB; DIPEPTIDYL CARBOXYPEPTIDASE; ENDOTHELIN 1; FATTY ACID; FRUCTOSE; GLUTATHIONE; GLUTATHIONE DISULFIDE; GLUTATHIONE PEROXIDASE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; KALLIKREIN; LACTATE DEHYDROGENASE; LIPID; LOW DENSITY LIPOPROTEIN CHOLESTEROL; NITRIC OXIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE P22PHOX; ROSMARINIC ACID; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; TRIACYLGLYCEROL; TROPONIN T; UNCLASSIFIED DRUG; VERY LOW DENSITY LIPOPROTEIN CHOLESTEROL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BLOOD PRESSURE REGULATION; BODY WEIGHT; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; CREATINE KINASE BLOOD LEVEL; DIET SUPPLEMENTATION; ENZYME ACTIVITY; FATTY ACID BLOOD LEVEL; HEART MUSCLE INJURY; HEART PROTECTION; HEART VENTRICLE HYPERTROPHY; HISTOPATHOLOGY; HYPERTENSION; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; INSULIN SENSITIVITY; LACTATE DEHYDROGENASE BLOOD LEVEL; LIPID BLOOD LEVEL; LIPID PEROXIDATION; MALE; METABOLIC DISORDER; NONHUMAN; OXIDATION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN METABOLISM; RAT; RISK REDUCTION; SYSTOLIC BLOOD PRESSURE; TRIACYLGLYCEROL BLOOD LEVEL;

ANIMALS; ANTIOXIDANTS; ASPARTATE AMINOTRANSFERASES; BLOOD GLUCOSE; BLOOD PRESSURE; BODY WEIGHT; CINNAMATES; CREATINE KINASE, MB FORM; DEPSIDES; DIETARY CARBOHYDRATES; ENDOTHELIN-1; FRUCTOSE; GENE EXPRESSION; HEART; HYPERINSULINISM; HYPERTENSION; INSULIN; INSULIN RESISTANCE; KALLIKREINS; L-LACTATE DEHYDROGENASE; LIPID METABOLISM; LIPIDS; MALE; MYOCARDIUM; NADPH OXIDASE; NITRATES; NITRIC OXIDE SYNTHASE TYPE III; ORGAN SIZE; OXIDATIVE STRESS; PEPTIDYL-DIPEPTIDASE A; RATS; RATS, WISTAR; TROPONIN C;

EID: 80955135026     PISSN: 01602446     EISSN: 15334023     Source Type: Journal    
DOI: 10.1097/FJC.0b013e31822c265d     Document Type: Article

References (41)

1. Witteles RM, Fowler MB. Insulin-resistant cardiomyopathy clinical evidence, mechanisms, and treatment options. J Am Coll Cardiol. 2008; 51:93-102.
2. Wylie-Rosett J, Segal-Isaacson CJ, Segal-Isaacson A. Carbohydrates and increases in obesity: does the type of carbohydrate make a difference? Obes Res. 2004;12:S124-S129.
3. Tran LT, Yuen VG, McNeill JH. The fructose-fed rat: a review on the mechanisms of fructose-induced insulin resistance and hypertension. Mol Cell Biochem. 2009;332:145-159.
4. Patel J, Iyer A, Brown L. Evaluation of the chronic complications of diabetes in a high fructose diet in rats. Indian J Biochem Biophys. 2009; 46:66-72.
5. Delbosc S, Paizanis E, Magous R, et al. Involvement of oxidative stress and NADPH oxidase activation in the development of cardiovascular complications in a model of insulin resistance, the fructose-fed rat. Atherosclerosis. 2005;179:43-49.
6. Poudyal H, Panchal S, Brown L. Comparison of purple carrot juice and b-carotene in a high-carbohydrate, high-fat diet-fed rat model of the metabolic syndrome. Br J Nutr. 2010;104:1322-1332.
7. Qiao S, Li W, Tsubouchi R, et al. Rosmarinic acid inhibits the formation of reactive oxygen and nitrogen species in RAW264.7 macrophages. Free Radic Res. 2005;39:995-1003.
8. Sá CM, Ramos AA, Azevedo MF, et al. Sage tea drinking improves lipid profile and antioxidant defences in humans. Int J Mol Sci. 2009;10: 3937-3950.
9. Vanithadevi B, Anuradha CV. Effect of rosmarinic acid on insulin sensitivity, glyoxalase system and oxidative events in liver of fructose-fed mice. Int J Diabetes Metab. 2008;16:35-44.
10. Ersoy S, Orhan I, Turan NN, et al. Endothelium-dependent induction of vasorelaxation by Melissa officinalis L. ssp. officinalis in rat isolated thoracic aorta. Phytomedicine. 2008;15:1087-1092.
11. Gutt M, Davis CL, Spitzer SB, et al. Validation of the insulin sensitivity index (ISI 0, 120): comparison with other measures. Diabetes Res Clin Pract. 2000;47:177-184.
12. Cacho J, Sevillano J, de Castro J, et al. Validation of simple indexes to assess insulin sensitivity during pregnancy inWistar and Sprague-Dawley rats. Am J Physiol Endocrinol Metab. 2008;295:E1269-E1276.
13. Katz A, Nambi SS, Mather K, et al. Quantitative insulin sensitivity check index: a simple, accurate method for assessing insulin sensitivity in humans. J Clin Endocrinol Metab. 2000;85:2402-2410.
14. Wroblewski F, La Due JS. Lactic dehydrogenase activity in blood. Proc Soc Exp Biol Med. 1955;90:210-213.
15. Trautschold I, Werle E, Schweitzer G. Kallikrein. In: Bregmeyer HU, ed. Methods in Enzymatic Analysis. Vol 2. Weinheim, Germany: Verlag Chemie; 1974:1031-1034.
16. Holmquist B, Bunning P, Riordan JF. A continuous spectrophotometric assay for angiotensin converting enzyme. Anal Biochem. 1979;95: 540-548.
17. Rock E, Astier C, Lab C, et al. Magnesium deficiency in rats induces a rise in plasma nitric oxide. Magnes Res. 1995;8:237-242.
18. Thirunavukkarasu V, Anitha Nandhini AT, Anuradha CV. Cardiac lipids and antioxidant status in high fructose rats and the effect of alpha-lipoic acid. Nutr Metab Cardiovasc Dis. 2004;14:351-357.
19. Witko-Sarsat V, Friedlander M, Capeillère-Blandin C, et al. Advanced oxidation protein products as a novel marker of oxidative stress in uremia. Kidney Int. 1996;49:1304-1313.
20. Benzie IFF, Strain JJ. The ferric reducing ability of plasma (FRAP) as a measure of ''antioxidant power'': the FRAP assay. Anal Biochem. 1996; 239:70-76.
21. Lowry OH, Rosebrough NJ, Farr AL, et al. Protein measurement with the Folin phenol reagent. J Biol Chem. 1951;193:265-275.
22. Mellor KM, Ritchie RH, Delbridge LMD. Reactive oxygen species and insulin resistant cardiomyopathy. Proc Aust Physiol Soc. 2009;40:27-35.
23. Holland JA, Pritchard KA, Pappolla MA, et al. Bradykinin induces superoxide anion release from human endothelial cells. J Cell Physiol. 1990;143:21-25.
24. Basciano H, Federico L, Adeli K. Fructose, insulin resistance, and metabolic dyslipidemia. Nutr Metab (Lond). 2005;2:5.
25. Qin B, Polansky MM, Harry D, et al. Green tea polyphenols improve cardiac muscle mRNA and protein levels of signal pathways related to insulin and lipid metabolism and inflammation in insulin-resistant rats. Mol Nutr Food Res. 2010;54:S14-S23.
26. Iyer A, Brown L. Lipid mediators and inflammation in glucose intolerance and insulin resistance. Drug Discov Today. 2010;7:e191-e197.
27. Liu SX, Hou FF, Guo ZJ, et al. Advanced oxidation protein products accelerate atherosclerosis through promoting oxidative stress and inflammation. Arterioscler Thromb Vasc Biol. 2006;26:1156-1162.
28. Mathew S, Menon RVG, Kurup PA. Effect of administration of vitamin A, ascorbic acid and nicotinamide adenine dinucleotide + flavin adenine nucleotide on severity of myocardial infarction induced by isoproterenol in rats. Indian J Exp Biol. 1985;23:500-504.
29. Van Der Laarse A. Hypothesis: troponin degradation is one of the factors responsible for deterioration of left ventricular function in heart failure. Cardiovasc Res. 2002;56:8-14.
30. Inoguchi T, Li P, Umeda F, et al. High glucose level and free fatty acid stimulate reactive oxygen species production through protein kinase Cdependent activation of NAD(P)H oxidase in cultured vascular cells. Diabetes. 2000;49:1939-1945.
31. Cuvelier M, Richard H, Berset C. Comparison of the antioxidative activity of some acid-phenols: structure-activity relationship. Biosci Biotech Biochem. 1992;26:324-325.
32. Lodovici M, Giovannelli L, Pitozzi V, et al. Oxidative DNA damage and plasma antioxidant capacity in type 2 diabetic patients with good and poor glycaemic control. Mutat Res. 2008;638:98-102.
33. Kim DS, Kim HR, Woo ER, et al. Inhibitory effects of rosmarinic acid on adriamycin-induced apoptosis in H9c2 cardiac muscle cells by inhibiting reactive oxygen species and the activations of c-Jun N-terminal kinase and extracellular signal-regulated kinase. Biochem Pharmacol. 2005;70: 1066-1078.
34. Li L, Tiana J, Lianga X. Regression of atherosclerosis by rosmarinic acid via regulating lipid metabolism and anti-inflammatory actions. J Mol Cell Cardiol. 2008;44:719.
35. Gamaro GD, Suyenaga E, Borsoi M, et al. Effect of rosmarinic and caffeic acids on inflammatory and nociception process in rats. ISRN Pharmacology. 2011;2011:1-6.
36. Sanbongi C, Takano H, Osakabe N et al. Rosmarinic acid inhibits lung injury induced by diesel exhaust particles. Free Radic Biol Med. 2003;34: 1060-1069.
37. Wang HD, Johns DG, Xu S, et al. Role of superoxide anion in regulating pressor and vascular hypertrophic response to angiotensin II. Am J Physiol. 2002;282:H1697-H1702.
38. Bohm F, Pernow J. The importance of endothelin-1 for vascular dysfunction in cardiovascular disease. Cardiovasc Res. 2007;76:8-18.
39. Ying CJ, Xu JW, Ikeda K, et al. Tea polyphenols regulate nicotinamide adenine dinucleotide phosphate oxidase subunit expression and ameliorate angiotensin II-induced hyperpermeability in endothelial cells. Hypertens Res. 2003;26:823-828.
40. Delbosc S, Morena M, Djouad F, et al. Statins, 3-hydroxy-3- methylglutaryl coenzyme A reductase inhibitors, are able to reduce superoxide anion production by NADPH oxidase in THP-1-erived monocytes. J Cardiovasc Pharmacol. 2002;40:611-617.
41. Dobrian AD, Schriver SD, Khraibi AA, et al. Pioglitazone prevents hypertension and reduces oxidative stress in diet-induced obesity. Hypertension. 2004;43:48-56.