Selective killing of cancer cells by iron oxide nanoparticles mediated through reactive oxygen species via p53 pathway

Journal of Nanoparticle Research

Volumn 15, Issue 1, 2013, Pages

  Ahamed, Maqusood ^a   Alhadlaq, Hisham A ^a   Khan, M A Majeed ^a   Akhtar, Mohd Javed ^b  

^a KING SAUD UNIVERSITY   (Saudi Arabia)

^b UNIVERSITY OF LUCKNOW   (India)

Author keywords

Anticancer activity; Apoptosis; Oxidative stress; p53

Indexed keywords

ASCORBIC ACID; BIOLOGICAL ORGANS; CELL CULTURE; CELL DEATH; DISEASES; DRUG DELIVERY; DRUG PRODUCTS; GENES; MAGNETIC NANOPARTICLES; MAGNETITE; MEDICAL APPLICATIONS; OXIDATIVE STRESS; OXYGEN; REACTIVE OXYGEN SPECIES; RESPIRATORY SYSTEM; TOXICITY;

ANTICANCER ACTIVITIES; BIOMEDICAL APPLICATIONS; HEPATOCELLULAR CARCINOMA; HUMAN LUNG FIBROBLASTS; IRON OXIDE NANOPARTICLE; NANOPARTICLE (NPS); POSSIBLE MECHANISMS; TUMOR SUPPRESSOR GENES;

IRON OXIDES;

ASCORBIC ACID; CASPASE 3; CASPASE 9; GLUCOSE; GLUTATHIONE; MAGNETITE NANOPARTICLE; MESSENGER RNA; PROTEIN P53; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CARCINOMA CELL; CELL KILLING; CELL STRAIN HEPG2; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DRUG SYNTHESIS; ENZYME ACTIVITY; HUMAN; HUMAN CELL; LIVER CELL; LUNG ADENOCARCINOMA; LUNG FIBROBLAST; NONHUMAN; OXIDATIVE STRESS; PARTICLE SIZE; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; SURFACE PROPERTY; UPREGULATION;

EID: 84870413165     PISSN: 13880764     EISSN: 1572896X     Source Type: Journal    
DOI: 10.1007/s11051-012-1225-6     Document Type: Article

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