Structure-activity relationship and preclinical evaluation of carbon-11-labeled ammonium salts as PET-myocardial perfusion imaging agents

Molecular Imaging and Biology

Volumn 14, Issue 5, 2012, Pages 625-636

  Ilovich, Ohad ^a   Abourbeh, Galith ^a   Bocher, Moshe ^a   Freedman, Nanette ^a   Billauer, Hana ^a   Dotan, Sharon ^a   Danenberg, Haim D ^a   Mishani, Eyal ^a  

^a HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

Author keywords

Ammonium salts; CAD; Carbon 11; MPI; PET

Indexed keywords

AMMONIUM DERIVATIVE; AMMONIUM SALT; CARBON METHYL DIMETHYL 1 NAPHTYLAMMONIUM TRIFLUOROMETHANESULFONATE C 11; CARBON METHYL DIMETHYL 3 TOLYL AMMONIUM IODIDE C 11; CARBON METHYL DIMETHYL DIPHENYL AMMONIUM TRIFLUOROMETHANESULFONATE C 11; DIAGNOSTIC AGENT; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARDIAC IMAGING; COMPUTER ASSISTED EMISSION TOMOGRAPHY; CONTROLLED STUDY; DIAGNOSTIC IMAGING; DRUG SCREENING; DRUG STABILITY; DRUG STRUCTURE; HEART INFARCTION; HEART MUSCLE ISCHEMIA; HEART MUSCLE PERFUSION; IN VITRO STUDY; ISOTOPE LABELING; LIPOPHILICITY; MALE; MICRO-COMPUTED TOMOGRAPHY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROCESS DEVELOPMENT; RADIOCHEMISTRY; RADIOISOTOPE DISTRIBUTION; RAT; STRUCTURE ACTIVITY RELATION; SWINE;

ANIMALS; CARBON RADIOISOTOPES; ISOTOPE LABELING; MALE; MICE; MICE, INBRED BALB C; MYOCARDIAL INFARCTION; MYOCARDIAL ISCHEMIA; MYOCARDIAL PERFUSION IMAGING; POSITRON-EMISSION TOMOGRAPHY; QUATERNARY AMMONIUM COMPOUNDS; RATS; SALTS; STRUCTURE-ACTIVITY RELATIONSHIP; SUS SCROFA; TIME FACTORS; TISSUE DISTRIBUTION;

MUS; RATTUS; SUIDAE;

EID: 84870409266     PISSN: 15361632     EISSN: 18602002     Source Type: Journal    
DOI: 10.1007/s11307-011-0539-6     Document Type: Article

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