Mechanism of uptake and retention of F-18 BMS-747158-02 in cardiomyocytes: A novel PET myocardial imaging agent

Journal of Nuclear Cardiology

Volumn 14, Issue 6, 2007, Pages 782-788

  Yalamanchili, Padmaja ^a   Wexler, Eric ^a   Hayes, Megan ^a   Yu, Ming ^a   Bozek, Jody ^a   Kagan, Mikhail ^a   Radeke, Heike S ^a   Azure, Michael ^a   Purohit, Ajay ^a   Casebier, David S ^a   Robinson, Simon P ^a  

^a BRISTOL MYERS SQUIBB   (United States)

Author keywords

BMS 747158 02; mitochondrial complex I; myocardial perfusion imaging; positron emission tomography

Indexed keywords

2 TERT BUTYL 4 CHLORO 5 [4 (2 FLUROETHOXYMETHYL)BENZYLOXY] 2H PYRIDAZIN 3 ONE F 18; BMS 747158 02; DEGUELIN; ROTENONE; TRACER; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; COW; DRUG BINDING; DRUG DISTRIBUTION; DRUG HALF LIFE; DRUG RETENTION; DRUG STRUCTURE; DRUG UPTAKE; HEART; HEART MUSCLE CELL; IC 50; IN VITRO STUDY; IN VIVO STUDY; INHIBITION KINETICS; LUNG PARENCHYMA; MALE; MITOCHONDRION; MOUSE; NEWBORN; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; RAT;

ANIMALS; CATTLE; CELLS, CULTURED; IMAGE ENHANCEMENT; MALE; METABOLIC CLEARANCE RATE; MICE; MICE, INBRED BALB C; MYOCYTES, CARDIAC; ORGAN SPECIFICITY; POSITRON-EMISSION TOMOGRAPHY; PYRIDAZINES; RADIOPHARMACEUTICALS; TISSUE DISTRIBUTION;

EID: 36048952709     PISSN: 10713581     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nuclcard.2007.07.009     Document Type: Article

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