Gravity-sensitive signaling drives 3-dimensional formation of multicellular thyroid cancer spheroids

FASEB Journal

Volumn 26, Issue 12, 2012, Pages 5124-5140

  Grosse, Jirka ^a   Wehland, Markus ^b   Pietsch, Jessica ^b   Schulz, Herbert ^c   Saar, Katrin ^c   Hübner, Norbert ^c   Eilles, Christoph ^a   Bauer, Johann ^d   Abou El Ardat, Khalil ^e,f   Baatout, Sarah ^e,f   Ma, Xiao ^g   Infanger, Manfred ^b   Hemmersbach, Ruth ^h   Grimm, Daniela ^b,g  

^a UNIVERSITY OF REGENSBURG   (Germany)

^b OTTO VON GUERICKE UNIVERSITY   (Germany)

^c MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^d MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

^e BELGIAN NUCLEAR RESEARCH CENTRE   (Belgium)

^f GHENT UNIVERSITY   (Belgium)

^g AARHUS UNIVERSITY   (Denmark)

^h GERMAN AEROSPACE CENTER DLR   (Germany)

Author keywords

Cytokines; Gene expression; Neoangiogenesis; Simulated microgravity

Indexed keywords

CONNECTIVE TISSUE GROWTH FACTOR; INTERLEUKIN 6; INTERLEUKIN 8; MITOGEN ACTIVATED PROTEIN KINASE 1; PROPIDIUM IODIDE; TRANSCRIPTION FACTOR RELA;

APOPTOSIS; ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; DOWN REGULATION; ENDOTHELIUM CELL; FLOW CYTOMETRY; GENE EXPRESSION; HUMAN; HUMAN CELL; MICROARRAY ANALYSIS; MICROGRAVITY; MULTICELLULAR THYROID CANCER SPHEROID; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; RNA ISOLATION; SIGNAL TRANSDUCTION; THYROID CANCER; WESTERN BLOTTING;

ANTIGENS, CD44; APOPTOSIS; BLOTTING, WESTERN; CELL CULTURE TECHNIQUES; CELL LINE, TUMOR; CLUSTER ANALYSIS; CONNECTIVE TISSUE GROWTH FACTOR; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; GRAVITATION; HUMANS; INTERLEUKIN-6; INTERLEUKIN-8; MALE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OSTEOPONTIN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SPHEROIDS, CELLULAR; TALIN; THYROID NEOPLASMS; TRANSCRIPTION FACTOR RELA;

EID: 84870356631     PISSN: None     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.12-215749     Document Type: Article

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