-
1
-
-
80054031545
-
Overcoming anoikis-pathways to anchorage-independent growth in cancer
-
Guadamillas, M.C. et a.l (2011) Overcoming anoikis-pathways to anchorage-independent growth in cancer. J. Cell Sci., 124, 3189-3197.
-
(2011)
J. Cell Sci.
, vol.124
, pp. 3189-3197
-
-
Guadamillas, M.C.1
-
2
-
-
0034678411
-
Activated Ras prevents downregulation of Bcl-X(L) triggered by detachment from the extracellular matrix A mechanism of Ras-induced resistance to anoikis in intestinal epithelial cells
-
Rosen, K. et al. (2000) Activated Ras prevents downregulation of Bcl-X(L) triggered by detachment from the extracellular matrix. A mechanism of Ras-induced resistance to anoikis in intestinal epithelial cells. J. Cell Biol., 149, 447-456.
-
(2000)
Cell Biol
, vol.149
, pp. 447-456
-
-
Rosen, K.1
-
3
-
-
1442308345
-
EphA2: a determinant of malignant cellular behavior and a potential therapeutic target in pancreatic adenocarcinoma
-
Duxbury, M.S. et al. (2004) EphA2: a determinant of malignant cellular behavior and a potential therapeutic target in pancreatic adenocarcinoma. Oncogene, 23, 1448-1456.
-
(2004)
Oncogene
, vol.23
, pp. 1448-1456
-
-
Duxbury, M.S.1
-
4
-
-
84861647455
-
Tumor suppressor protein kinase Chk2 is a mediator of anoikis of intestinal epithelial cells
-
Yoo, B.H. et al (2012) Tumor suppressor protein kinase Chk2 is a mediator of anoikis of intestinal epithelial cells. Int. J. Cancer, 131, 357-366.
-
(2012)
Int. J. Cancer
, vol.131
, pp. 357-366
-
-
Yoo, B.H.1
-
5
-
-
22144499164
-
Claudin-1 regulates cellular transformation and metastatic behavior in colon cancer
-
Dhawan, P. et al. (2005) Claudin-1 regulates cellular transformation and metastatic behavior in colon cancer. J. Clin. Invest., 115, 1765-1776.
-
(2005)
J. Clin. Invest.
, vol.115
, pp. 1765-1776
-
-
Dhawan, P.1
-
6
-
-
58149379295
-
Claudin 1 overexpression increases invasion and is associated with aggressive histological features in oral squamous cell carcinoma
-
Dos Reis, P.P. et al. (2008) Claudin 1 overexpression increases invasion and is associated with aggressive histological features in oral squamous cell carcinoma. Cancer, 113, 3169-3180.
-
(2008)
Cancer
, vol.113
, pp. 3169-3180
-
-
Dos Reis, P.P.1
-
7
-
-
15544385589
-
Increased expressions of claudin-1 and claudin-7 during the progression of cervical neoplasia
-
Lee, J.W. et al. (2005) Increased expressions of claudin-1 and claudin-7 during the progression of cervical neoplasia. Gynecol. Oncol., 97, 53-59.
-
(2005)
Gynecol. Oncol.
, vol.97
, pp. 53-59
-
-
Lee, J.W.1
-
8
-
-
44949181869
-
Is Src the key to understanding metastasis and developing new treatments for colon cancer? Nat
-
Chen, J. (2008) Is Src the key to understanding metastasis and developing new treatments for colon cancer? Nat. Clin. Pract. Gastroenterol. Hepatol., 5, 306-307.
-
(2008)
Clin. Pract. Gastroenterol. Hepatol.
, vol.5
, pp. 306-307
-
-
Chen, J.1
-
9
-
-
71749089459
-
Migfilin interacts with Src and contributes to cellmatrix adhesion-mediated survival signaling
-
Zhao, J. et al. (2009) Migfilin interacts with Src and contributes to cellmatrix adhesion-mediated survival signaling. J. Biol. Chem., 284, 34308-34320.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 34308-34320
-
-
Zhao, J.1
-
10
-
-
0036048217
-
Src-induced de-regulation of E-cadherin in colon cancer cells requires integrin signalling
-
Avizienyte, E. et al. (2002) Src-induced de-regulation of E-cadherin in colon cancer cells requires integrin signalling. Nat. Cell Biol., 4, 632-638.
-
(2002)
Nat. Cell Biol.
, vol.4
, pp. 632-638
-
-
Avizienyte, E.1
-
11
-
-
0037038686
-
Src activation regulates anoikis in human colon tumor cell lines
-
Windham, C. et al (2002) Src activation regulates anoikis in human colon tumor cell lines. Oncogene, 21, 7797-7807.
-
(2002)
Oncogene
, vol.21
, pp. 7797-7807
-
-
Windham, C.1
-
12
-
-
67650021249
-
Intestinal epithelial cancer cell anoikis resistance: EGFR-mediated sustained activation of Src overrides Fak-dependent signaling to MEK/Erk and/or PI3-K/Akt-1
-
Demers, M.J. et al. (2009) Intestinal epithelial cancer cell anoikis resistance: EGFR-mediated sustained activation of Src overrides Fak-dependent signaling to MEK/Erk and/or PI3-K/Akt-1. J. Cell. Biochem., 107, 639-654.
-
(2009)
J. Cell. Biochem.
, vol.107
, pp. 639-654
-
-
Demers, M.J.1
-
13
-
-
41149176839
-
B1 integrin/Fak/Src signaling in intestinal epithelial crypt cell survival: integration of complex regulatory mechanisms
-
Bouchard, V. et al. (2008) B1 integrin/Fak/Src signaling in intestinal epithelial crypt cell survival: integration of complex regulatory mechanisms. Apoptosis, 13, 531-542.
-
(2008)
Apoptosis
, vol.13
, pp. 531-542
-
-
Bouchard, V.1
-
14
-
-
79958807321
-
Ephexin4 and EphA2 mediate resistance to anoikis through RhoG and phosphatidylinositol 3-kinase
-
Harada, K. et al. (2011) Ephexin4 and EphA2 mediate resistance to anoikis through RhoG and phosphatidylinositol 3-kinase. Exp. Cell Res., 317, 1701-1713.
-
(2011)
Exp. Cell Res.
, vol.317
, pp. 1701-1713
-
-
Harada, K.1
-
15
-
-
78650622904
-
The sensors and regulators of cellmatrix surveillance in anoikis resistance of tumors
-
Nagaprashantha, L.D. et al. (2011) The sensors and regulators of cellmatrix surveillance in anoikis resistance of tumors. Int. J. Cancer, 128, 743-752.
-
(2011)
Int. J. Cancer
, vol.128
, pp. 743-752
-
-
Nagaprashantha, L.D.1
-
16
-
-
10944223361
-
Altered regulation of Src upon cell detachment protects human lung adenocarcinoma cells from anoikis
-
Wei, L. et al. (2004) Altered regulation of Src upon cell detachment protects human lung adenocarcinoma cells from anoikis. Oncogene, 23, 9052-9061.
-
(2004)
Oncogene
, vol.23
, pp. 9052-9061
-
-
Wei, L.1
-
17
-
-
18944395927
-
Bim regulation of lumen formation in cultured mammary epithelial acini is targeted by oncogenes
-
Reginato, M.J. et al. (2005) Bim regulation of lumen formation in cultured mammary epithelial acini is targeted by oncogenes. Mol. Cell. Biol., 25, 4591-4601.
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 4591-4601
-
-
Reginato, M.J.1
-
18
-
-
49649109588
-
SRC directly phosphorylates Bif-1 and prevents its interaction with Bax and the initiation of anoikis
-
Yamaguchi, H. et al. (2008) SRC directly phosphorylates Bif-1 and prevents its interaction with Bax and the initiation of anoikis. J. Biol. Chem., 283, 19112-19118.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 19112-19118
-
-
Yamaguchi, H.1
-
19
-
-
65249089049
-
FAK engages multiple pathways to maintain survival of fibroblasts and epithelia: differential roles for paxillin and p130Cas
-
Zouq, N.K. et al. (2009) FAK engages multiple pathways to maintain survival of fibroblasts and epithelia: differential roles for paxillin and p130Cas. J. Cell. Sci., 122(Pt 3), 357-367.
-
(2009)
J. Cell. Sci.
, vol.122
, Issue.PART 3
, pp. 357-367
-
-
Zouq, N.K.1
-
20
-
-
62149084526
-
Paxillin-Y118 phosphorylation contributes to the control of Src-induced anchorage-independent growth by FAK and adhesion
-
Sachdev, S. et al. (2009) Paxillin-Y118 phosphorylation contributes to the control of Src-induced anchorage-independent growth by FAK and adhesion. BMC Cancer, 9, 12.
-
(2009)
BMC Cancer
, vol.9
, pp. 12
-
-
Sachdev, S.1
-
21
-
-
33644776869
-
PI3K and ERK 1-2 regulate early stages during head regeneration in hydra
-
Manuel, G.C. et al. (2006) PI3K and ERK 1-2 regulate early stages during head regeneration in hydra. Dev. Growth Differ., 48, 129-138.
-
(2006)
Dev. Growth Differ.
, vol.48
, pp. 129-138
-
-
Manuel, G.C.1
-
22
-
-
80055105655
-
Src kinase integrates PI3K/Akt and MAPK/ERK1/2 pathways in T3-induced Na-K-ATPase activity in adult rat alveolar cells
-
Lei, J. et al. (2011) Src kinase integrates PI3K/Akt and MAPK/ERK1/2 pathways in T3-induced Na-K-ATPase activity in adult rat alveolar cells. Am. J. Physiol. Lung Cell Mol. Physiol., 301, L765-L771.
-
(2011)
Am. J. Physiol. Lung Cell Mol. Physiol.
, vol.301
-
-
Lei, J.1
-
23
-
-
77951169413
-
ErbB2 requires integrin α5 for anoikis resistance via Src regulation of receptor activity in human mammary epithelial cells
-
Haenssen, K.K. et al (2010) ErbB2 requires integrin α5 for anoikis resistance via Src regulation of receptor activity in human mammary epithelial cells. J. Cell Sci., 123, 1373-1382.
-
(2010)
J. Cell Sci.
, vol.123
, pp. 1373-1382
-
-
Haenssen, K.K.1
-
24
-
-
67650599486
-
Connexin 43 gap junction plaque endocytosis implies molecular remodelling of ZO-1 and c-Src partners
-
Gilleron, J. et al. (2009) Connexin 43 gap junction plaque endocytosis implies molecular remodelling of ZO-1 and c-Src partners. Commun. Integr. Biol., 2, 104-106.
-
(2009)
Commun. Integr. Biol.
, vol.2
, pp. 104-106
-
-
Gilleron, J.1
-
25
-
-
83355174042
-
The Src homology 3 domain is required for junctional adhesion molecule binding to the third PDZ domain of the scaffolding protein ZO-1
-
Nomme, J. et al. (2011) The Src homology 3 domain is required for junctional adhesion molecule binding to the third PDZ domain of the scaffolding protein ZO-1. J. Biol. Chem., 286, 43352-43360.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 43352-43360
-
-
Nomme, J.1
-
26
-
-
0033552629
-
Direct binding of three tight junction-associated MAGUKs, ZO-1, ZO-2, and ZO-3, with the COOH termini of claudins
-
Itoh, M. et al. (1999) Direct binding of three tight junction-associated MAGUKs, ZO-1, ZO-2, and ZO-3, with the COOH termini of claudins. J. Cell Biol., 147, 1351-1363.
-
(1999)
J. Cell Biol.
, vol.147
, pp. 1351-1363
-
-
Itoh, M.1
-
27
-
-
67649891795
-
Current management of colorectal hepatic metastasis
-
Mayo, S.C. et al. (2009) Current management of colorectal hepatic metastasis. Expert Rev. Gastroenterol. Hepatol., 3, 131-144.
-
(2009)
Expert Rev. Gastroenterol. Hepatol.
, vol.3
, pp. 131-144
-
-
Mayo, S.C.1
-
28
-
-
34249989451
-
Claudin-1 overexpression in melanoma is regulated by PKC and contributes to melanoma cell motility
-
Leotlela, P.D. et al. (2007) Claudin-1 overexpression in melanoma is regulated by PKC and contributes to melanoma cell motility. Oncogene, 26, 3846-3856.
-
(2007)
Oncogene
, vol.26
, pp. 3846-3856
-
-
Leotlela, P.D.1
-
29
-
-
0037038686
-
Src activation regulates anoikis in human colon tumor cell lines
-
Windham, T.C. et al. (2002) Src activation regulates anoikis in human colon tumor cell lines. Oncogene, 21, 7797-7807.
-
(2002)
Oncogene
, vol.21
, pp. 7797-7807
-
-
Windham, T.C.1
-
31
-
-
0037171468
-
Increased Bcl-xL expression mediates v-Srcinduced resistance to anoikis in intestinal epithelial cells
-
Coll, M.L. et al. (2002) Increased Bcl-xL expression mediates v-Srcinduced resistance to anoikis in intestinal epithelial cells. Oncogene, 21, 2908-2913.
-
(2002)
Oncogene
, vol.21
, pp. 2908-2913
-
-
Coll, M.L.1
-
32
-
-
63049092454
-
ERK/BCL-2 pathway in the resistance of pancreatic cancer to anoikis
-
Galante, J.M. et al. (2009) ERK/BCL-2 pathway in the resistance of pancreatic cancer to anoikis. J. Surg. Res., 152, 18-25.
-
(2009)
J. Surg. Res.
, vol.152
, pp. 18-25
-
-
Galante, J.M.1
-
33
-
-
37549048249
-
The BCL-2 protein family: opposing activities that mediate cell death
-
Youle, R.J. et al. (2008) The BCL-2 protein family: opposing activities that mediate cell death. Nat. Rev. Mol. Cell Biol., 9, 47-59.
-
(2008)
Nat. Rev. Mol. Cell Biol.
, vol.9
, pp. 47-59
-
-
Youle, R.J.1
-
34
-
-
84862494616
-
Integrin/Fak/Src-mediated regulation of cell survival and anoikis in human intestinal epithelial crypt cells: selective engagement and roles of PI3-K isoform complexes
-
Beauséjour, M. et al. (2012) Integrin/Fak/Src-mediated regulation of cell survival and anoikis in human intestinal epithelial crypt cells: selective engagement and roles of PI3-K isoform complexes. Apoptosis, 17, 566-578.
-
(2012)
Apoptosis
, vol.17
, pp. 566-578
-
-
Beauséjour, M.1
-
35
-
-
84862103119
-
PI3K-independent AKT activation in cancers: a treasure trove for novel therapeutics
-
Mahajan, K. et al. (2012) PI3K-independent AKT activation in cancers: a treasure trove for novel therapeutics. J. Cell. Physiol., 227, 3178-3184.
-
(2012)
J. Cell. Physiol.
, vol.227
, pp. 3178-3184
-
-
Mahajan, K.1
-
36
-
-
81855228088
-
Claudin-1 up-regulates the repressor ZEB-1 to inhibit E-cadherin expression in colon cancer cells
-
Singh, A.B. et al. (2011) Claudin-1 up-regulates the repressor ZEB-1 to inhibit E-cadherin expression in colon cancer cells. Gastroenterology, 141, 2140-2153.
-
(2011)
Gastroenterology
, vol.141
, pp. 2140-2153
-
-
Singh, A.B.1
-
37
-
-
84862323792
-
Cooperate concept of metastasis: site-specific requirement of activated differentiation and dynamic deterioration
-
Wilmanns, C. et al. (2012) Cooperate concept of metastasis: site-specific requirement of activated differentiation and dynamic deterioration. Cancer Metastasis Rev., 31, 269-276.
-
(2012)
Cancer Metastasis Rev
, vol.31
, pp. 269-276
-
-
Wilmanns, C.1
-
38
-
-
65549123466
-
Molecular mechanisms controlling E-cadherin expression in breast cancer
-
Baranwal, S. et al. (2009) Molecular mechanisms controlling E-cadherin expression in breast cancer. Biochem. Biophys. Res. Commun., 384, 6-11.
-
(2009)
Biochem. Biophys. Res. Commun.
, vol.384
, pp. 6-11
-
-
Baranwal, S.1
-
39
-
-
47549098263
-
E-cadherin as an indicator of mesenchymal to epithelial reverting transitions during the metastatic seeding of disseminated carcinomas
-
Wells, A. et al. (2008) E-cadherin as an indicator of mesenchymal to epithelial reverting transitions during the metastatic seeding of disseminated carcinomas. Clin. Exp. Metastasis, 25, 621-628.
-
(2008)
Clin. Exp. Metastasis
, vol.25
, pp. 621-628
-
-
Wells, A.1
-
40
-
-
77957174099
-
Purvalanol A, a CDK inhibitor, effectively suppresses Src-mediated transformation by inhibiting both CDKs and c-Src
-
Hikita, T. et al. (2010) Purvalanol A, a CDK inhibitor, effectively suppresses Src-mediated transformation by inhibiting both CDKs and c-Src. Genes Cells, 15, 1051-1062.
-
(2010)
Genes Cells
, vol.15
, pp. 1051-1062
-
-
Hikita, T.1
-
41
-
-
33947547489
-
Dysregulation of claudin-7 leads to loss of E-cadherin expression and the increased invasion of esophageal squamous cell carcinoma cells
-
Lioni, M. et al. (2007) Dysregulation of claudin-7 leads to loss of E-cadherin expression and the increased invasion of esophageal squamous cell carcinoma cells. Am. J. Pathol., 170, 709-721.
-
(2007)
Am. J. Pathol.
, vol.170
, pp. 709-721
-
-
Lioni, M.1
-
42
-
-
79951669627
-
Hepatitis C virus entry into hepatocytes: molecular mechanisms and targets for antiviral therapies
-
Zeisel, M.B. et al. (2011) Hepatitis C virus entry into hepatocytes: molecular mechanisms and targets for antiviral therapies. J. Hepatol., 54, 566-576.
-
(2011)
J. Hepatol.
, vol.54
, pp. 566-576
-
-
Zeisel, M.B.1
-
43
-
-
84856210973
-
Inflammation and disruption of the mucosal architecture in claudin-7-deficient mice
-
Ding, L. et al. (2012) Inflammation and disruption of the mucosal architecture in claudin-7-deficient mice. Gastroenterology, 142, 305-315.
-
(2012)
Gastroenterology
, vol.142
, pp. 305-315
-
-
Ding, L.1
-
44
-
-
33748286819
-
Integrin-regulated FAK-Src signaling in normal and cancer cells
-
Mitra, S.K. et al. (2006) Integrin-regulated FAK-Src signaling in normal and cancer cells. Curr. Opin. Cell Biol., 18, 516-523.
-
(2006)
Curr. Opin. Cell Biol.
, vol.18
, pp. 516-523
-
-
Mitra, S.K.1
-
45
-
-
80051726684
-
Src/FAK-mediated regulation of E-cadherin as a mechanism for controlling collective cell movement: insights from in vivo imaging
-
Serrels, A. et al. (2011) Src/FAK-mediated regulation of E-cadherin as a mechanism for controlling collective cell movement: insights from in vivo imaging. Cell Adh. Migr., 5, 360-365.
-
(2011)
Cell Adh. Migr.
, vol.5
, pp. 360-365
-
-
Serrels, A.1
-
46
-
-
77449143786
-
Integrin signaling and lung cancer
-
Caccavari, F. et al. (2010) Integrin signaling and lung cancer. Cell Adh. Migr., 4, 124-129.
-
(2010)
Cell Adh. Migr.
, vol.4
, pp. 124-129
-
-
Caccavari, F.1
-
47
-
-
69849101598
-
PKCepsilon regulation of an alpha5 integrin-ZO-1 complex controls lamellae formation in migrating cancer cells
-
Tuomi, S. et al. (2009) PKCepsilon regulation of an alpha5 integrin-ZO-1 complex controls lamellae formation in migrating cancer cells. Sci. Signal., 2, ra32.
-
(2009)
Sci. Signal.
, vol.2
-
-
Tuomi, S.1
-
48
-
-
0037067660
-
Zonula occludens-1 is a scaffolding protein for signaling molecules Galpha(12) directly binds to the Src homology 3 domain and regulates paracellular permeability in epithelial cells
-
Meyer, T.N. et al. (2002) Zonula occludens-1 is a scaffolding protein for signaling molecules. Galpha(12) directly binds to the Src homology 3 domain and regulates paracellular permeability in epithelial cells. J. Biol. Chem., 277, 24855-24858.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 24855-24858
-
-
Meyer, T.N.1
-
49
-
-
77953764845
-
Crosstalk between desmoglein-2/desmocollin-2/Src kinase and coxsackie and adenovirus receptor/ZO-1 protein complexes, regulates blood-testis barrier dynamics
-
Lie, P.P. et al. (2010) Crosstalk between desmoglein-2/desmocollin-2/Src kinase and coxsackie and adenovirus receptor/ZO-1 protein complexes, regulates blood-testis barrier dynamics. Int. J. Biochem. Cell Biol., 42, 975-986.
-
(2010)
Int. J. Biochem. Cell Biol.
, vol.42
, pp. 975-986
-
-
Lie, P.P.1
-
50
-
-
0037009005
-
Protein phosphatase 2A associates with and regulates atypical PKC and the epithelial tight junction complex
-
Nunbhakdi-Craig, V. et al. (2002) Protein phosphatase 2A associates with and regulates atypical PKC and the epithelial tight junction complex. J. Cell Biol., 158, 967-978.
-
(2002)
J. Cell Biol.
, vol.158
, pp. 967-978
-
-
Nunbhakdi-Craig, V.1
-
51
-
-
79952800345
-
Claudin-2 forms homodimers and is a component of a high molecular weight protein complex
-
Van Itallie, C.M. et al. (2011) Claudin-2 forms homodimers and is a component of a high molecular weight protein complex. J. Biol. Chem., 286, 3442-3450.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 3442-3450
-
-
Van Itallie, C.M.1
|