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Volumn 11, Issue , 2012, Pages

Constitutive over expression of IL-1β, IL-6, NF-κB, and Stat3 is a potential cause of lung tumorgenesis in urethane (ethyl carbamate) induced Balb/c mice

Author keywords

Adenocarcinoma; NF B; proinflammatory cytokines; Stat3; urethane

Indexed keywords

CYTOKINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; PHOSPHATE BUFFERED SALINE; STAT3 PROTEIN; URETHAN;

EID: 84870352761     PISSN: 09746773     EISSN: 14773163     Source Type: Journal    
DOI: 10.4103/1477-3163.98965     Document Type: Article
Times cited : (44)

References (40)
  • 2
    • 57349095906 scopus 로고    scopus 로고
    • The international epidemiology of lung cancer: Geographical distribution and secular trends
    • Youlden DR, Cramb SM, Baade PD. The International Epidemiology of Lung Cancer: geographical distribution and secular trends. J Thorac Oncol 2008;3:819-31.
    • (2008) J Thorac Oncol , vol.3 , pp. 819-831
    • Youlden, D.R.1    Cramb, S.M.2    Baade, P.D.3
  • 3
    • 0036463481 scopus 로고    scopus 로고
    • Focus on lung cancer
    • DOI 10.1016/S1535-6108(02)00027-2
    • Minna JD, Roth JA, Gazadar AF. Focus on lung cancer. Cancer Cell 2002;1:49-52. (Pubitemid 41039175)
    • (2002) Cancer Cell , vol.1 , Issue.1 , pp. 49-52
    • Minna, J.D.1    Roth, J.A.2    Gazdar, A.F.3
  • 4
    • 33244466256 scopus 로고    scopus 로고
    • Quantitative nuclear texture features analysis confirms WHO classification 2004 for lung carcinomas
    • DOI 10.1038/modpathol.3800541, PII 3800541
    • Schmid K, Angestein N, Geleff S, Gschwandtner A. Quantitative texture features analysis confirms WHO classification 2004 for lung carcinomas. Mod Pathol 2006;19:453-9. (Pubitemid 43277000)
    • (2006) Modern Pathology , vol.19 , Issue.3 , pp. 453-459
    • Schmid, K.1    Angerstein, N.2    Geleff, S.3    Gschwendtner, A.4
  • 5
    • 0023909902 scopus 로고
    • The pathology of lung cancer-changing concepts and newer diagnostic techniques
    • Gazdar AF, Linnoila RI. The pathology of lung cancer-changing concepts and newer diagnostic techniques. Semin Oncol 1988;15: 215-25.
    • (1988) Semin Oncol , vol.15 , pp. 215-225
    • Gazdar, A.F.1    Linnoila, R.I.2
  • 6
    • 5444256371 scopus 로고    scopus 로고
    • Inflammation as a tumor promoter in cancer induction
    • DOI 10.1016/j.semcancer.2004.06.006, PII S1044579X04000495
    • Philip M, Rowley DA, Schreiber H. Inflammation as a tumor promoter in cancer induction. Semin Cancer Biol 2004;14:433-9. (Pubitemid 39360991)
    • (2004) Seminars in Cancer Biology , vol.14 , Issue.6 , pp. 433-439
    • Philip, M.1    Rowley, D.A.2    Schreiber, H.3
  • 8
    • 0018131777 scopus 로고
    • Formation and determination of ethyl carbamate in tobacco and tobacco smoke
    • Schmetiz I, Chiong KG, Hoffmann DJ. Formation and dtermination of ethyl carbamate in tobacco and tobacco smoke. Anal Toxicol 1978;2:265-8. (Pubitemid 9076497)
    • (1978) Journal of Analytical Toxicology , vol.2 , Issue.6 , pp. 265-268
    • Schmeltz, I.1    Chiong, K.G.2    Hoffmann, D.3
  • 9
    • 0016927250 scopus 로고
    • Ethylcarbamate in fermented beverages and foods. I. Naturally occurring ethylcarbamate
    • Ough CS. Ethylcarbamate in fermented beverages and foods. I. Naturally occurring ethylcarbamate. J Agric Food Chem 1976;24:323-8.
    • (1976) J Agric Food Chem , vol.24 , pp. 323-328
    • Ough, C.S.1
  • 10
    • 0035560834 scopus 로고    scopus 로고
    • Development in the production and application of dimethylcarbonate
    • Delledonne D, Rivetti F, Romano U. Development in the production and application of dimethylcarbonate. Applied catalysis A: General 2001;221:241-51.
    • (2001) Applied Catalysis A: General , vol.221 , pp. 241-251
    • Delledonne, D.1    Rivetti, F.2    Romano, U.3
  • 11
    • 34250169397 scopus 로고    scopus 로고
    • Synthesis of diethyl carbonate by catalytic alcoholysis of urea
    • DOI 10.1016/j.fuproc.2007.04.003, PII S0378382007000768
    • Wang D, Yang B, Zhai X, Zhou L. Synthesis of diethyl carbonate by catalytic alcoholysis of urea. Fuel Processing Technol 2007;88:807-12. (Pubitemid 46898734)
    • (2007) Fuel Processing Technology , vol.88 , Issue.8 , pp. 807-812
    • Wang, D.1    Yang, B.2    Zhai, X.3    Zhou, L.4
  • 13
    • 85039458650 scopus 로고    scopus 로고
    • Ethyl carbamate and hydrocyanic acid in food and beverages. Scientific opinion of the panel on contaminants
    • Alexander J, Auounsson GA, Benford D, Cockburn A, Cravedi J, Doglitti E, et al. Ethyl carbamate and hydrocyanic acid in food and beverages. Scientific opinion of the panel on contaminants. EFSA Journal 2007;551:1-44.
    • (2007) EFSA Journal , vol.551 , pp. 1-44
    • Alexander, J.1    Auounsson, G.A.2    Benford, D.3    Cockburn, A.4    Cravedi, J.5    Doglitti, E.6
  • 14
    • 33846597544 scopus 로고    scopus 로고
    • Analysis of ethyl carbamate in Korean soy sauce using high-performance liquid chromatography with fluorescence detection or tandem mass spectrometry and gas chromatography with mass spectrometry
    • DOI 10.1016/j.foodcont.2006.05.013, PII S0956713506001393
    • Park SK, Kim CT, Lee JW, Jhee OH, Om AS, Kang JS, et al. Analysis of ethyl carbamate in Korean soy sauce using high-performance liquid chromatography with fluorescence detection or tandem mass spectrometry and gas spectrometry with mass spectrometry. Food Control 2007;18:975-82. (Pubitemid 46172852)
    • (2007) Food Control , vol.18 , Issue.8 , pp. 975-982
    • Park, S.-K.1    Kim, C.T.2    Lee, J.-W.3    Jhee, O.H.4    Om, A.S.5    Kang, J.S.6    Moon, T.W.7
  • 15
    • 0031804606 scopus 로고    scopus 로고
    • Molecular comparison of human and mouse pulmonary adenocarcinomas
    • Malkinson AM. Molecular comparison of human and mouse pulmonary adenocarcinomas. Exp Lung Res 1998;24:541-55. (Pubitemid 28308950)
    • (1998) Experimental Lung Research , vol.24 , Issue.4 , pp. 541-555
    • Malkinson, A.M.1
  • 16
    • 0034997385 scopus 로고    scopus 로고
    • Primary lung tumors in mice as an aid for understanding, preventing, and treating human adenocarcinoma of the lung
    • Malikinson AM. Primary lung tumors in mice as an aid for understanding, preventing, and treating human adenocarcinoma of the lung. Lung Cancer 2001;32:265-79.
    • (2001) Lung Cancer , vol.32 , pp. 265-279
    • Malikinson, A.M.1
  • 17
    • 0020531450 scopus 로고
    • Major effect on susceptibility to urethan-induced pulmonary adenoma by a single gene in BALB/cBy mice
    • Malkinson AM, Beer DS. Major effect on susceptibility to urethan-induced pulmonary adenoma by a single gene in BALB/cBy mice. J Natl Cancer Inst 1983;70:931-6. (Pubitemid 13101493)
    • (1983) Journal of the National Cancer Institute , vol.70 , Issue.5 , pp. 931-936
    • Malkinson, A.M.1    Beer, D.S.2
  • 18
    • 0026652576 scopus 로고
    • Primary lung tumors in mice: An experimentally manipulable model of human adenocarcinoma
    • Malkinson AM. Primary lung tumors in mice: an experimentally manipulable model of human adenocarcinoma. Cancer Res 1992;52(9 Suppl):2670s-76s.
    • (1992) Cancer Res , vol.52 , Issue.9 SUPPL.
    • Malkinson, A.M.1
  • 20
    • 0035104892 scopus 로고    scopus 로고
    • Atypical adenomatous hyperplasia of the lung: A probable forerunner in the development of adenocarcinoma of the lung
    • DOI 10.1038/modpathol.3880259
    • Mori M, Rao SK, Popper HH, Cagle PT, Fraire AE. Atypical adenomatous hyperplasia of the lung: a probable forerunner in the development of adenocarcinoma of the lung. Mod Pathol 2001;14:72-84. (Pubitemid 32173389)
    • (2001) Modern Pathology , vol.14 , Issue.2 , pp. 72-84
    • Mori, M.1    Rao, S.K.2    Popper, H.H.3    Cagle, P.T.4    Fraire, A.E.5
  • 21
    • 33947515407 scopus 로고    scopus 로고
    • Tumor signaling to the bone marrow changes the phenotype of monocytes and pulmonary macrophages during urethane-induced primary lung tumorigenesis in A/J mice
    • DOI 10.2353/ajpath.2007.060566
    • Redente EF, Orliky DJ, Bouchard RJ, Malkinson AM. Tumor signaling to the bone marrow changes the phenotype of monocytes and pulmonary macrophages during urethane-induced primary lung tumorigenesis in A/J mice. Am J Pathol 2007;170:693-708. (Pubitemid 47339405)
    • (2007) American Journal of Pathology , vol.170 , Issue.2 , pp. 693-708
    • Redente, E.F.1    Orlicky, D.J.2    Bouchard, R.J.3    Malkinson, A.M.4
  • 23
  • 25
    • 0031593664 scopus 로고    scopus 로고
    • Role of NF-κB in immune and inflammatory responses in the gut
    • Neurath MF, Becker C, Barbulescu K. Role of NF-kappaB in immune and inflammatory responses in the gut. Gut 1998;43:856-60. (Pubitemid 28539668)
    • (1998) Gut , vol.43 , Issue.6 , pp. 856-860
    • Neurath, M.F.1    Becker, C.2    Barbulescu, K.3
  • 26
    • 0028349735 scopus 로고
    • Stat3: A STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6
    • Zhong Z, Wen Z, Darnell JE Jr. Stat3: a SATA family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6. Science 1994;264:95-8. (Pubitemid 24144493)
    • (1994) Science , vol.264 , Issue.5155 , pp. 95-98
    • Zhong, Z.1    Wen, Z.2    Darnell Jr., J.E.3
  • 27
    • 33744548730 scopus 로고    scopus 로고
    • Signal transduction of inflammatory cytokines and tumor development
    • DOI 10.1111/j.1349-7006.2006.00197.x
    • Yoshimura A. Signal transduction of inflammatory cytokines and tumor development. Cancer Sci 2006;97:439-47. (Pubitemid 43811583)
    • (2006) Cancer Science , vol.97 , Issue.6 , pp. 439-447
    • Yoshimura, A.1
  • 28
    • 33947500486 scopus 로고    scopus 로고
    • Cytokines are a therapeutic target for the prevention of inflammation-induced cancers
    • Rose-John S, Schooltink H. Cytokines are a therapeutic target for the prevention of inflammation-induced cancers. Recent Results Cancer Res 2007;174:57-66.
    • (2007) Recent Results Cancer Res , vol.174 , pp. 57-66
    • Rose-John, S.1    Schooltink, H.2
  • 29
    • 34848903024 scopus 로고    scopus 로고
    • Role of IL-1-mediated inflammation in tumor angiogenesis
    • Voronov E, Carmi Y, Apte RN. Role of IL-1-mediated inflammation in tumor angiogenesis. Adv Exp Med Biol 2007;601:265-70.
    • (2007) Adv Exp Med Biol , vol.601 , pp. 265-270
    • Voronov, E.1    Carmi, Y.2    Apte, R.N.3
  • 30
    • 33750135226 scopus 로고    scopus 로고
    • Receptor-mediated tobacco toxicity: Cooperation of the Ras/Raf-1/MEK1/ERK and JAK-2/STAT-3 pathways downstream of alpha7 nicotinic receptor in oral keratinocytes
    • DOI 10.1096/fj.06-6191com
    • Arredono J, Chernyavsky AI, Jolkovsky DL, Pinkerton KE, Grando SA. Receptor-mediated tobacco toxicity: cooperation of the Ras/Raf-1/MEK1/ERK and JAK-2/STAT-3 pathways downstream of alpha7 nicotinic receptor in oral keratinocytes. FASEB J 2006;20:2093-101. (Pubitemid 44953908)
    • (2006) FASEB Journal , vol.20 , Issue.12 , pp. 2093-2101
    • Arredondo, J.1    Chernyavsky, A.I.2    Jolkovsky, D.L.3    Pinkerton, K.E.4    Grando, S.A.5
  • 31
    • 4043088499 scopus 로고    scopus 로고
    • IKKβ links inflammation and tumorigenesis in a mouse model of colitis-associated cancer
    • DOI 10.1016/j.cell.2004.07.013, PII S0092867404006713
    • Greten FR, Eckmann L, Greten TF, Park JM, Li ZW, Egan LJ, et al. I beta links inflammation and tumorigenesis in a mouse model of colitis associated cancer. Cell 2004;118:285-96. (Pubitemid 39061110)
    • (2004) Cell , vol.118 , Issue.3 , pp. 285-296
    • Greten, F.R.1    Eckmann, L.2    Greten, T.F.3    Park, J.M.4    Li, Z.-W.5    Egan, L.J.6    Kagnoff, M.F.7    Karin, M.8
  • 32
    • 69149098253 scopus 로고    scopus 로고
    • Signal transducer and activator of transcription-3, inflammation, and cancer: How intimate is the relationship?
    • Aggarawal BB, Kunnumakkara AB, Harikumar KB, Gupta SR, Tharakan ST, Koca C, et al. Signal transducer and activator of transcription-3, inflammation, and cancer: how intimate is the relationship? Ann N Y Acad Sci 2009;1171:59-76.
    • (2009) Ann N y Acad Sci , vol.1171 , pp. 59-76
    • Aggarawal, B.B.1    Kunnumakkara, A.B.2    Harikumar, K.B.3    Gupta, S.R.4    Tharakan, S.T.5    Koca, C.6
  • 33
    • 0346505340 scopus 로고    scopus 로고
    • The IKK NF-κB system: A treasure trove for drug development
    • Karin M, Yamamoto Y, Wang QM. The I NF-kappa B: system a treasure trove for drug development. Nat Rev Drug Discov 2004;3:17-26. (Pubitemid 38088695)
    • (2004) Nature Reviews Drug Discovery , vol.3 , Issue.1 , pp. 17-26
    • Karin, M.1    Yamamoto, Y.2    Wang, Q.M.3
  • 34
    • 0030840464 scopus 로고    scopus 로고
    • STATs and gene regulation
    • DOI 10.1126/science.277.5332.1630
    • Darnell JE Jr . STATs and gene regulation. Science 1997;277:1630-5. (Pubitemid 27446219)
    • (1997) Science , vol.277 , Issue.5332 , pp. 1630-1635
    • Darnell Jr., J.E.1
  • 35
    • 0442323562 scopus 로고    scopus 로고
    • NF-kappaB: Tumor promoter or suppressor?
    • Perkins ND. NF-kappaB: tumor promoter or suppressor? Trends Cell Biol 2004;14:64-9.
    • (2004) Trends Cell Biol , vol.14 , pp. 64-69
    • Perkins, N.D.1
  • 36
    • 33947417336 scopus 로고    scopus 로고
    • Regulation of metastases by signal transducer and activator of transcription 3 signaling pathway: Clinical implications
    • DOI 10.1158/1078-0432.CCR-06-2313
    • Huang S. Regulation of metastases by signal transducer and activator of transcription 3 signaling pathway: clinical implications. Clin Cancer Res 2007;13:1362-6. (Pubitemid 46450423)
    • (2007) Clinical Cancer Research , vol.13 , Issue.5 , pp. 1362-1366
    • Huang, S.1
  • 38
    • 2442685645 scopus 로고    scopus 로고
    • Stat3 activation regulates the expression of matrix metalloproteinase-2 and tumor invasion and metastasis
    • DOI 10.1038/sj.onc.1207383
    • Xie TX, Wei D, Liu M, Gao AC, Ali-Osman F, Sawaya R, et al. Stat3 activation regulates the expression of matrix metalloproteinase-2 and tumor invasion and metastasis. Oncogene 2004;23:3550-60. (Pubitemid 38658421)
    • (2004) Oncogene , vol.23 , Issue.20 , pp. 3550-3560
    • Xie, T.-X.1    Wei, D.2    Liu, M.3    Gao, A.C.4    Ali-Osman, F.5    Sawaya, R.6    Huang, S.7
  • 39
    • 0034885358 scopus 로고    scopus 로고
    • New insights into the role of nuclear factor-κB in cell growth regulation
    • Chen F, Castranova V, Shi X. New insights into the role of nuclear factor-B in cell growth regulation. Am J Pathol 2001;159:387-97. (Pubitemid 32751067)
    • (2001) American Journal of Pathology , vol.159 , Issue.2 , pp. 387-397
    • Chen, F.1    Castranova, V.2    Shi, X.3
  • 40
    • 33646160623 scopus 로고    scopus 로고
    • Inflammation, a key event in cancer development
    • Lu H, Ouyang W, Huang C. Inflammation, a key event in cancer development. Mol Cancer Res 2006;4:221-33.
    • (2006) Mol Cancer Res , vol.4 , pp. 221-233
    • Lu, H.1    Ouyang, W.2    Huang, C.3


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