CD4+CD28null T lymphocyte frequency, a new marker of cardiovascular risk: Relationship with polycystic ovary syndrome phenotypes

Fertility and Sterility

Volumn 98, Issue 6, 2012, Pages 1609-1615

  Moro, Francesca ^a   Morciano, Andrea ^a   Tropea, Anna ^a   Sagnella, Francesca ^a   Palla, Carola ^a   Scarinci, Elisa ^a   Cosentino, Nicola ^a   Niccoli, Giampaolo ^a   Liuzzo, Giovanna ^a   Crea, Filippo ^a   Lanzone, Antonio ^b   Apa, Rosanna ^a  

^a CATHOLIC UNIVERSITY   (Italy)

^b OASI RESEARCH INSTITUTE IRCCS   (Italy)

Author keywords

cardiovascular risk; CD4+CD28null; phenotypes; Polycystic ovary syndrome; Rotterdam criteria

Indexed keywords

ANDROGEN; C REACTIVE PROTEIN; CHOLESTEROL; GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PRASTERONE SULFATE; SEX HORMONE BINDING GLOBULIN; TESTOSTERONE; TRIACYLGLYCEROL;

ADULT; AGE; AMENORRHEA; ANDROGEN BLOOD LEVEL; ANOVULATION; ARTICLE; BODY MASS; CARDIOVASCULAR RISK; CD4 LYMPHOCYTE COUNT; CD4+ CD28 NULL T LYMPHOCYTE; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; CORRELATIONAL STUDY; DYSLIPIDEMIA; FAMILY HISTORY; FEMALE; GLUCOSE BLOOD LEVEL; HUMAN; HYPERANDROGENISM; HYPERTENSION; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; MAJOR CLINICAL STUDY; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; OBSERVATIONAL STUDY; OVARY; OVARY POLYCYSTIC DISEASE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RETROSPECTIVE STUDY; RISK ASSESSMENT; SMOKING; T LYMPHOCYTE; TESTOSTERONE BLOOD LEVEL; TRIACYLGLYCEROL BLOOD LEVEL; WAIST HIP RATIO;

ADOLESCENT; ADULT; BIOLOGICAL MARKERS; CD4 LYMPHOCYTE COUNT; CD8-POSITIVE T-LYMPHOCYTES; COHORT STUDIES; COMORBIDITY; CORONARY ARTERY DISEASE; DIABETES MELLITUS, TYPE 2; FEMALE; HUMANS; ITALY; POLYCYSTIC OVARY SYNDROME; PREVALENCE; RISK ASSESSMENT; YOUNG ADULT;

EID: 84870340449     PISSN: 00150282     EISSN: 15565653     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2012.08.015     Document Type: Article

References (43)

1. E. Diamanti-Kandarakis, C.R. Kouli, A.T. Bergiele, F.A. Filandra, T.C. Tsianateli, and G.G. Spina A survey of the polycystic ovary syndrome in the Greek island of Lesbos: hormonal and metabolic profile J Clin Endocrinol Metab 84 1999 4006 4011 (Pubitemid 30644187)
2. R. Homburg Polycystic ovary syndrome - from gynaecological curiosity to multisystem endocrinopathy Hum Reprod 11 1996 29 39 (Pubitemid 26047668)
3. L.J. Rajashekar, D. Krishna, and M. Patil Polycystic ovaries and infertility: our experience J Hum Reprod Sci 1 2008 65 72
4. L.J. Moran, J.D. Cameron, B.J. Strauss, and H.J. Teede Vascular function in the diagnostic categories of polycystic ovary syndrome Hum Reprod 26 2011 2192 2199
5. J. Zawdaki, and A. Dunaif Diagnostic criteria for polycystic ovary syndrome: toward a rational approach A. Dunaif, J. Givens, F. Haseltine, G. Marrian, Polycystic ovary syndrome. Current issues in endocrinology and metabolism vol. 4 1992 Blackwell Scientific Boston 377 384
6. E.S. Knochenhauer, T.J. Key, M. Kahsar-Miller, W. Waggoner, L.R. Boots, and R. Azziz Prevalence of the polycystic ovary syndrome in unselected black and white women of the southeastern United States: a prospective study J Clin Endocrinol Metab 83 1998 3078 3082 (Pubitemid 28500937)
7. M. Asuncion, R.M. Calvo, J.L. San Millan, J. Sancho, S. Avila, and H.F. Escobar-Morreale A prospective study of the prevalence of the polycystic ovary syndrome in unselected Caucasian women from Spain J Clin Endocrinol Metab 85 2000 2434 2438 (Pubitemid 32269197)
8. R. Azziz, K.S. Woods, R. Reyna, T.J. Key, E.S. Knochenhauer, and B.O. Yildiz The prevalence and features of the polycystic ovary syndrome in an unselected population J Clin Endocrinol Metab 89 2004 2745 2749 (Pubitemid 38766360)
9. Rotterdam ESHRE/ASRM-Sponsored PCOS Consensus Workshop Group Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome Fertil Steril 81 2004 19 25
10. W.A. March, V.M. Moore, K.J. Willson, D.I. Phillips, R.J. Norman, and M.J. Davies The prevalence of polycystic ovary syndrome in a community sample assessed under contrasting diagnostic criteria Hum Reprod 25 2010 544 551
11. L. Moran, and H. Teede Metabolic features of the reproductive phenotypes of polycystic ovary syndrome Hum Reprod Update 15 2009 477 488
12. R.A. Wild, E. Carmina, E. Diamanti-Kandarakis, A. Dokras, H.F. Escobar- Morreale, and W. Futterweit Assessment of cardiovascular risk and prevention of cardiovascular disease in women with the polycystic ovary syndrome: a consensus statement by the Androgen Excess and Polycystic Ovary Syndrome (AE-PCOS) Society J Clin Endocrinol Metab 95 2010 2038 2049
13. null T lymphocytes are expanded in young women with polycystic ovary syndrome Fertil Steril 95 2011 2651 2654
14. null T cells in coronary artery disease: when helpers become killers Cardiovasc Res 81 2009 11 19
15. null T cells in autoimmune disease: pathogenic features and decreased susceptibility to immunoregulation J Immunol 179 2007 6514 6523
16. + T cells in severe rheumatoid arthritis Arthritis Rheum 40 1997 1060 1114
17. A.N. Vallejo, C.M. Weyand, and J.J. Goronzy T-cell senescence: a culprit of immune abnormalities in chronic inflammation and persistent infection Trends Mol Med 10 2004 119 124 (Pubitemid 38293347)
18. - T lymphocytes contribute to early atherosclerotic damage in rheumatoid arthritis patients Circulation 109 2004 2744 2748 (Pubitemid 38737922)
19. null T cells are independently associated with cardiovascular disease in ESRD patients Nephrol Dial Transplant 25 2010 3640 3646
20. - lymphocytes and the extent and severity of coronary artery disease Int J Cardiol 135 2009 27 35
21. null T-lymphocytes in diabetic patients: exploring new pathogenetic mechanisms of increased cardiovascular risk in diabetes mellitus Eur Heart J 32 2011 1214 1226
22. G. Liuzzo, S.L. Kopecky, R.L. Frye, W.M. O'Fallon, A. Maseri, and J.J. Goronzy Perturbation of the T-cell repertoire in patients with unstable angina Circulation 100 1999 2135 2139
23. G. Liuzzo, J.J. Goronzy, H. Yang, S.L. Kopecky, D.R. Holmes, and R.L. Frye Monoclonal T-cell proliferation and plaque instability in acute coronary syndromes Circulation 101 2000 2883 2888 (Pubitemid 30415876)
24. null T lymphocytes and recurrence of acute coronary events J Am Coll Cardiol 50 2007 1450 1458 (Pubitemid 47494592)
25. D. Ferriman, and J.D. Gallwey Clinical assessment of body hair growth in women J Clin Endocrinol Metab 21 1961 1440 1447
26. M. Cappel, D. Mauger, and D. Thiboutot Correlation between serum levels of insulin-like growth factor 1, dehydroepiandrosterone sulfate, and dihydrotestosterone and acne lesion counts in adult women Arch Dermatol 141 2005 333 338 (Pubitemid 40365449)
27. M. Ciampelli, F. Leoni, F. Cucinelli, S. Mancuso, S. Panunzi, and A. de Gaetano Assessment of insulin sensitivity from measurements in the fasting state and during an oral glucose tolerance test in polycystic ovary syndrome and menopausal patients J Clin Endocrinol Metab 90 2005 1398 1406 (Pubitemid 40463995)
28. G. Liuzzo, A.N. Vallejo, S.L. Kopecky, R.L. Frye, D.R. Holmes, J.J. Goronzy, and C.M. Weyand Molecular fingerprint of interferon-gamma signaling in unstable angina Circulation 103 2001 1509 1514 (Pubitemid 32226257)
29. T. Nakajima, S. Schulte, K.J. Warrington, S.L. Kopecky, R.L. Frye, and J.J. Goronzy T-cell-mediated lysis of endothelial cells in acute coronary syndromes Circulation 105 2002 570 575 (Pubitemid 34123430)
30. S. Pryshchep, K. Sato, J.J. Goronzy, and C.M. Weyand T Cell recognition and killing of vascular smooth muscle cells in acute coronary syndrome Circ Res 98 2006 1168 1176 (Pubitemid 43948103)
31. null T cells in patients with acute coronary syndromes Circulation 109 2004 1230 1235 (Pubitemid 38372781)
32. - T cell proinflammatory and effector responses in patients with coronary artery disease J Immunol 181 2008 5233 5241
33. T.M. Barber, J.A. Wass, M.I. McCarthy, and S. Franks Metabolic characteristics of women with polycystic ovaries and oligo-amenorrhoea but normal androgen levels: implications for the management of polycystic ovary syndrome Clin Endocrinol (Oxf) 66 2007 513 517 (Pubitemid 46434931)
34. I. Lambrinoudaki Cardiovascular risk in postmenopausal women with the polycystic ovary syndrome Maturitas 68 2011 13 16
35. F. Mehrabian, B. Khani, R. Kelishadi, and N. Kermani The prevalence of metabolic syndrome and insulin resistance according to the phenotypic subgroups of polycystic ovary syndrome in a representative sample of Iranian females J Res Med Sci 16 2011 763 769
36. E. Koiou, K. Tziomalos, I. Katsikis, E. Kalaitzakis, E.A. Kandaraki, and E.A. Tsourdi Circulating platelet-derived microparticles are elevated in women with polycystic ovary syndrome diagnosed with the 1990 criteria and correlate with serum testosterone levels Eur J Endocrinol 165 2011 63 68
37. R. Shroff, C.H. Syrop, W. Davis, B.J. van Voorhis, and A. Dokras Risk of metabolic complications in the new PCOS phenotypes based on the Rotterdam criteria Fertil Steril 88 2007 1389 1395 (Pubitemid 350030974)
38. D. Wiltgen, and P.M. Spritzer Variations in metabolic and cardiovascular risk in women with different polycystic ovary syndrome phenotypes Fertil Steril 94 2010 2493 2496
39. M. Yilmaz, U. Isaoglu, I.B. Delibas, and S. Kadanali Anthropometric, clinical and laboratory comparison of four phenotypes of polycystic ovary syndrome based on Rotterdam criteria J Obstet Gynaecol Res 37 2011 1020 1026
40. M. Rizzo, K. Berneis, M. Hersberger, I. Pepe, G. di Fede, and G.B. Rini Milder forms of atherogenic dyslipidemia in ovulatory versus anovulatory polycystic ovary syndrome phenotype Hum Reprod 24 2009 2286 2292
41. B. Dilbaz, E. Ozkaya, M. Cinar, E. Cakir, and S. Dilbaz Cardiovascular disease risk characteristics of the main polycystic ovary syndrome phenotypes Endocrine 39 2011 272 277
42. M.C. Amato, M. Verghi, A. Galluzzo, and C. Giordano The oligomenorrhoic phenotypes of polycystic ovary syndrome are characterized by a high visceral adiposity index: a likely condition of cardiometabolic risk Hum Reprod 26 2011 1486 1494
43. M. Guo, Z.J. Chen, N.S. Macklon, Y.H. Shi, H.E. Westerveld, and M.J. Eijkemans Cardiovascular and metabolic characteristics of infertile Chinese women with PCOS diagnosed according to the Rotterdam consensus criteria Reprod Biomed Online 21 2010 572 580