Preparation of a nanoscale baohuoside I-phospholipid complex and determination of its absorption: In vivo and in vitro evaluations

International Journal of Nanomedicine

Volumn 7, Issue , 2012, Pages 4907-4916

  Jin, Xin ^a,b   Zhang, Zhen Hai ^a   Sun, E ^a   Qian, Qian ^a   Tan, Xiao bin ^a   Jia, Xiao bin ^a  

^a KEY LABORATORY OF NEW DRUG DELIVERY SYSTEM OF CHINESE MATERIA MEDICA   (China)

^b NANJING UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

Bioavailability; Caco 2 cell monolayer; Nanoscale phospholipid complex; Oral absorption

Indexed keywords

BAOHUOSIDE I PHOSPHOLIPID COMPLEX; PHOSPHOLIPID DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CELL CULTURE; CELL STRAIN CACO 2; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BIOAVAILABILITY; IN VITRO STUDY; IN VIVO STUDY; MALE; MAXIMUM PLASMA CONCENTRATION; MEAN RESIDENCE TIME; NONHUMAN; PARTICLE SIZE; PHYSICAL CHEMISTRY; RAT; SINGLE DRUG DOSE; TIME TO MAXIMUM PLASMA CONCENTRATION; TRANSMISSION ELECTRON MICROSCOPY; ULTRAVIOLET SPECTROSCOPY;

ABSORPTION; ADMINISTRATION, ORAL; ANIMALS; ANTINEOPLASTIC AGENTS; CACO-2 CELLS; DIFFUSION; FLAVONOIDS; HUMANS; MALE; MATERIALS TESTING; METABOLIC CLEARANCE RATE; NANOCAPSULES; ORGAN SPECIFICITY; PHOSPHOLIPIDS; RATS, SPRAGUE-DAWLEY; TISSUE DISTRIBUTION;

RATTUS;

EID: 84870329055     PISSN: 11769114     EISSN: 11782013     Source Type: Journal    
DOI: 10.2147/IJN.S35965     Document Type: Article

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