Association of genetic variants for colorectal cancer differs by subtypes of polyps in the colorectum

Carcinogenesis

Volumn 33, Issue 12, 2012, Pages 2417-2423

  Zhang, Ben ^a,b   Shrubsole, Martha J ^a,b,c,d   Li, Guoliang ^a   Cai, Qiuyin ^a,b,c   Edwards, Todd ^a,b   Smalley, Walter E ^a,d   Ness, Reid M ^a,d   Zheng, Wei ^a,b,c,d  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^c VANDERBILT INGRAM CANCER CENTER   (United States)

^d GERIATRIC RESEARCH EDUCATION AND CLINICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ADVANCED CANCER; ARTICLE; CANCER PATIENT; CANCER RISK; CARCINOGENESIS; CASE CONTROL STUDY; COLONOSCOPY; COLORECTAL ADENOMA; COLORECTAL CANCER; COLORECTAL POLYP; CONTROLLED STUDY; FEMALE; GENE FREQUENCY; GENE LOCUS; GENETIC ASSOCIATION; GENETIC RISK; GENETIC VARIABILITY; HOSPITAL PATIENT; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTIPLE CANCER; PHENOTYPE; PRIORITY JOURNAL; SCORING SYSTEM; SINGLE NUCLEOTIDE POLYMORPHISM; TUMOR LOCALIZATION;

AGED; CASE-CONTROL STUDIES; COLONIC POLYPS; COLORECTAL NEOPLASMS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENETIC VARIATION; GENOME-WIDE ASSOCIATION STUDY; HUMANS; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK;

EID: 84870321806     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgs308     Document Type: Article

References (35)

1. Vogelstein, B. et al. (1988) Genetic alterations during colorectal-tumor development. N. Engl. J. Med., 319, 525-532.
2. Fearon, E.R. et al. (1990) A genetic model for colorectal tumorigenesis. Cell, 61, 759-767.
3. Jemal, A. et al. (2010) Cancer statistics, 2010. CA Cancer J. Clin., 60, 277-300.
4. Cunningham, D. et al. (2010) Colorectal cancer. Lancet, 375, 1030-1047.
5. Kamangar, F. et al. (2006) Patterns of cancer incidence, mortality, and prevalence across five continents: defining priorities to reduce cancer disparities in different geographic regions of the world. J. Clin. Oncol., 24, 2137-2150.
6. Potter, J.D. (1999) Colorectal cancer: molecules and populations. J. Natl. Cancer Inst., 91, 916-932.
7. Winawer, S.J. et al. (1993) Prevention of colorectal cancer by colonoscopic polypectomy. The National Polyp Study Workgroup. N. Engl. J. Med., 329, 1977-1981.
8. Hiraoka, S. et al. (2010) The presence of large serrated polyps increases risk for colorectal cancer. Gastroenterology, 139, 1503-1510, 1510.e1.
9. Schreiner, M.A. et al. (2010) Proximal and large hyperplastic and nondysplastic serrated polyps detected by colonoscopy are associated with neoplasia. Gastroenterology, 139, 1497-1502.
10. Noffsinger, A.E. (2009) Serrated polyps and colorectal cancer: new pathway to malignancy. Annu. Rev. Pathol., 4, 343-364.
11. Leggett, B. et al. (2010) Role of the serrated pathway in colorectal cancer pathogenesis. Gastroenterology, 138, 2088-2100.
12. Zanke, B.W. et al. (2007) Genome-wide association scan identifies a colorectal cancer susceptibility locus on chromosome 8q24. Nat. Genet., 39, 989-994.
13. Tomlinson, I. et al. (2007) A genome-wide association scan of tag SNPs identifies a susceptibility variant for colorectal cancer at 8q24.21. Nat. Genet., 39, 984-988.
14. Broderick, P. et al. (2007) A genome-wide association study shows that common alleles of SMAD7 influence colorectal cancer risk. Nat. Genet., 39, 1315-1317.
15. Jaeger, E. et al. (2008) Common genetic variants at the CRAC1 (HMPS) locus on chromosome 15q13.3 influence colorectal cancer risk. Nat. Genet., 40, 26-28.
16. Tenesa, A. et al. (2008) Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21. Nat. Genet., 40, 631-637.
17. Tomlinson, I.P. et al. (2008) A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3. Nat. Genet., 40, 623-630.
18. Houlston, R.S. et al. (2008) Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer. Nat. Genet., 40, 1426-1435.
19. Houlston, R.S. et al. (2010) Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26.2, 12q13.13 and 20q13.33. Nat. Genet., 42, 973-977.
20. Cui, R. et al. (2011) Common variant in 6q26-q27 is associated with distal colon cancer in an Asian population. Gut., 60, 799-805.
21. Shrubsole, M.J. et al. (2008) Alcohol drinking, cigarette smoking, and risk of colorectal adenomatous and hyperplastic polyps. Am. J. Epidemiol., 167, 1050-1058.
22. Fu, Z. et al. (2011) Association of meat intake and meat-derived mutagen exposure with the risk of colorectal polyps by histologic type. Cancer Prev. Res. (Phila), 4, 1686-1697.
23. Li, Y. et al. (2010) MaCH: using sequence and genotype data to estimate haplotypes and unobserved genotypes. Genet. Epidemiol., 34, 816-834.
24. Wigginton, J.E. et al. (2005) A note on exact tests of Hardy-Weinberg equilibrium. Am. J. Hum. Genet., 76, 887-893.
25. Lau, J. et al. (1997) Quantitative synthesis in systematic reviews. Ann. Intern. Med., 127, 820-826.
26. Berndt, S.I. et al. (2008) Pooled analysis of genetic variation at chromosome 8q24 and colorectal neoplasia risk. Hum. Mol. Genet., 17, 2665-2672.
27. He, J. et al. (2011) Generalizability and epidemiologic characterization of eleven colorectal cancer GWAS hits in multiple populations. Cancer Epidemiol. Biomarkers Prev., 20, 70-81.
28. Wark, P.A. et al. (2009) Family history of colorectal cancer: a determinant of advanced adenoma stage or adenoma multiplicity? Int. J. Cancer, 125, 413-420.
29. Jasperson, K.W. et al. (2010) Hereditary and familial colon cancer. Gastroenterology, 138, 2044-2058.
30. Jass, J.R. (2000) Familial colorectal cancer: pathology and molecular characteristics. Lancet Oncol., 1, 220-226.
31. Abuli, A. et al. (2010) Susceptibility genetic variants associated with colorectal cancer risk correlate with cancer phenotype. Gastroenterology, 139, 788-796, 796.e1.
32. Bufill, J.A. (1990) Colorectal cancer: evidence for distinct genetic categories based on proximal or distal tumor location. Ann. Intern. Med., 113, 779-788.
33. Iacopetta, B. (2002) Are there two sides to colorectal cancer? Int. J. Cancer, 101, 403-408.
34. Boland, C.R. et al. (2010) Microsatellite instability in colorectal cancer. Gastroenterology, 138, 2073-2087.
35. Zheng, J. et al. (2011) A comparison of approaches to account for uncertainty in analysis of imputed genotypes. Genet. Epidemiol., 35, 102-110.