Characterization of Oligomers of Heterogeneous Size as Precursors of Amyloid Fibril Nucleation of an SH3 Domain: An Experimental Kinetics Study

PLoS ONE

Volumn 7, Issue 11, 2012, Pages

  Ruzafa, David ^a   Morel, Bertrand ^a   Varela, Lorena ^a   Azuaga, Ana I ^a   Conejero Lara, Francisco ^a  

^a UNIVERSITY OF GRANADA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID PRECURSOR PROTEIN; AMYLOID PROTEIN; FODRIN; MONOMER; OLIGOMER; POLYPEPTIDE; PROTEIN SH3; SODIUM CHLORIDE; THIOFLAVINE;

ARTICLE; CHEMICAL ANALYSIS; CHEMICAL REACTION; COMPLEX FORMATION; CONCENTRATION RESPONSE; CONFORMATIONAL TRANSITION; EXPERIMENTAL STUDY; KINETICS; MATHEMATICAL MODEL; NUCLEATION; OLIGOMERIZATION; PROTEIN AGGREGATION; PROTEIN ANALYSIS; PROTEIN DEPLETION; PROTEIN DOMAIN; PROTEIN STRUCTURE; PROTEIN UNFOLDING; QUANTITATIVE ANALYSIS; THERMODYNAMICS;

AMYLOID; HUMANS; KINETICS; MUTATION; PROTEIN BINDING; PROTEIN FOLDING; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, SECONDARY; SODIUM CHLORIDE; SRC HOMOLOGY DOMAINS; THERMODYNAMICS;

EID: 84870260214     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0049690     Document Type: Article

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