-
1
-
-
33746377894
-
Protein misfolding, functional amyloid, and human disease
-
Chiti, E, and C. M. Dobson. 2006. Protein misfolding, functional amyloid, and human disease. Annu. Rev. Biochem. 75:333-366.
-
(2006)
Annu. Rev. Biochem.
, vol.75
, pp. 333-366
-
-
Chiti, E.1
Dobson, C.M.2
-
2
-
-
0034718157
-
Alzheimer's amyloid fibrils: Structure and assembly
-
Serpell, L. C. 2000. Alzheimer's amyloid fibrils: structure and assembly. Biochim. Biophys. Acta. 1502:16-30.
-
(2000)
Biochim. Biophys. Acta.
, vol.1502
, pp. 16-30
-
-
Serpell, L.C.1
-
3
-
-
37549031260
-
Amyloid - A state in many guises: Survival of the fittest fibril fold
-
Pedersen, J. S., and D. E. Otzen. 2008. Amyloid - a state in many guises: survival of the fittest fibril fold. Protein Sci. 17:2-10.
-
(2008)
Protein Sci.
, vol.17
, pp. 2-10
-
-
Pedersen, J.S.1
Otzen, D.E.2
-
4
-
-
0030908095
-
Models of amyloid seeding in Alzheimer's disease and scrapie: Mechanistic truths and physiological consequences of the time-dependent solubility of amyloid proteins
-
Harper, J. D., and P. T. Lansbury, Jr. 1997. Models of amyloid seeding in Alzheimer's disease and scrapie: mechanistic truths and physiological consequences of the time-dependent solubility of amyloid proteins. Annu. Rev. Biochem. 66:385-407.
-
(1997)
Annu. Rev. Biochem.
, vol.66
, pp. 385-407
-
-
Harper, J.D.1
Lansbury Jr., P.T.2
-
5
-
-
3342902033
-
Modulation of S6 fibrillation by unfolding rates and gatekeeper residues
-
Pedersen, J. S., G. Christensen, and D. E. Otzen. 2004. Modulation of S6 fibrillation by unfolding rates and gatekeeper residues. J. Mol. Biol. 341:575-588.
-
(2004)
J. Mol. Biol.
, vol.341
, pp. 575-588
-
-
Pedersen, J.S.1
Christensen, G.2
Otzen, D.E.3
-
6
-
-
0037255361
-
Assembly of amyloid protofibrils via critical oligomers - A novel pathway of amyloid formation
-
Modler, A. J., K. Gast, G. Damaschun. 2003. Assembly of amyloid protofibrils via critical oligomers - a novel pathway of amyloid formation. J. Mol. Biol. 325:135-148.
-
(2003)
J. Mol. Biol.
, vol.325
, pp. 135-148
-
-
Modler, A.J.1
Gast, K.2
Damaschun, G.3
-
7
-
-
0030614627
-
Observation of metastable A/3 amyloid protofibrils by atomic force microscopy
-
Harper, J. D., S. S. Wong, P. T. Lansbury. 1997. Observation of metastable A/3 amyloid protofibrils by atomic force microscopy. Chem. Biol. 4:119-125.
-
(1997)
Chem. Biol.
, vol.4
, pp. 119-125
-
-
Harper, J.D.1
Wong, S.S.2
Lansbury, P.T.3
-
8
-
-
23444445907
-
Competing pathways determine fibril morphology in the self-assembly of β2-microglobulin into amyloid
-
Gosal, W. S., I. J. Morten, S. E. Radford. 2005. Competing pathways determine fibril morphology in the self-assembly of β2-microglobulin into amyloid. J. Mol. Biol. 351:850-864.
-
(2005)
J. Mol. Biol.
, vol.351
, pp. 850-864
-
-
Gosal, W.S.1
Morten, I.J.2
Radford, S.E.3
-
9
-
-
0042744699
-
Amyloid protofilaments from the calcium-binding protein equine lysozyme: Formation of ring and linear structures depends on pH and metal ion concentration
-
Malisauskas, M., V. Zamotin, L. A. Morozova-Roche. 2003. Amyloid protofilaments from the calcium-binding protein equine lysozyme: formation of ring and linear structures depends on pH and metal ion concentration. J. Mol. Biol. 330:879-890.
-
(2003)
J. Mol. Biol.
, vol.330
, pp. 879-890
-
-
Malisauskas, M.1
Zamotin, V.2
Morozova-Roche, L.A.3
-
10
-
-
30344457011
-
Probing the mechanism of amyloidogenesis through a tandem repeat of the PI3-SH3 domain suggests a generic model for protein aggregation and fibril formation
-
Bader, R., R. Bamford, C. M. Dobson. 2006. Probing the mechanism of amyloidogenesis through a tandem repeat of the PI3-SH3 domain suggests a generic model for protein aggregation and fibril formation. J. Mol. Biol. 356:189-208.
-
(2006)
J. Mol. Biol.
, vol.356
, pp. 189-208
-
-
Bader, R.1
Bamford, R.2
Dobson, C.M.3
-
11
-
-
33847662852
-
Soluble protein oligomers in neurodegeneration: Lessons from the Alzheimer's amyloid β -peptide
-
Haass, C., and D. J. Selkoe. 2007. Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid β -peptide. Nat. Rev. Mol. Cell Biol. 8:101-112.
-
(2007)
Nat. Rev. Mol. Cell Biol.
, vol.8
, pp. 101-112
-
-
Haass, C.1
Selkoe, D.J.2
-
12
-
-
37349075778
-
Congo red and thioflavin-T analogs detect A3 oligomers
-
Maezawa, I., H.-S. Hong, L. W. Jin. 2008. Congo red and thioflavin-T analogs detect A3 oligomers. J. Neurochem. 104:457-468.
-
(2008)
J. Neurochem.
, vol.104
, pp. 457-468
-
-
Maezawa, I.1
Hong, H.-S.2
Jin, L.W.3
-
13
-
-
0034714351
-
Nucleated conformational conversion and the replication of conformational information by a prion determinant
-
Serio, T. R., A. G. Cashikar, S. L. Lindquist. 2000. Nucleated conformational conversion and the replication of conformational information by a prion determinant. Science. 289:1317-1321.
-
(2000)
Science.
, vol.289
, pp. 1317-1321
-
-
Serio, T.R.1
Cashikar, A.G.2
Lindquist, S.L.3
-
14
-
-
3342906956
-
Fibrillation of carrier protein albebetin and its biologically active constructs. Multiple oligomeric intermediates and pathways
-
Morozova-Roche, L. A., V. Zamotin, M. P. Kirpichnikov. 2004. Fibrillation of carrier protein albebetin and its biologically active constructs. Multiple oligomeric intermediates and pathways. Biochemistry. 43:9610-9619.
-
(2004)
Biochemistry.
, vol.43
, pp. 9610-9619
-
-
Morozova-Roche, L.A.1
Zamotin, V.2
Kirpichnikov, M.P.3
-
15
-
-
0037422540
-
Amyloid 3-protein (A3) assembly: Aβ 40 and Aβ 42 oligomerize through distinct pathways
-
Bitan, G., M. D. Kirkitadze, D. B. Teplow. 2003. Amyloid 3-protein (A3) assembly: Aβ 40 and Aβ 42 oligomerize through distinct pathways. Proc. Natl. Acad. Sci. USA. 100:330-335.
-
(2003)
Proc. Natl. Acad. Sci. USA.
, vol.100
, pp. 330-335
-
-
Bitan, G.1
Kirkitadze, M.D.2
Teplow, D.B.3
-
16
-
-
0031825181
-
Obligatory steps in protein folding and the conformational diversity of the transition state
-
Martinez, J. C., M. T. Pisabarro, and L. Serrano. 1998. Obligatory steps in protein folding and the conformational diversity of the transition state. Nat. Struct. Biol. 5:721-729.
-
(1998)
Nat. Struct. Biol.
, vol.5
, pp. 721-729
-
-
Martinez, J.C.1
Pisabarro, M.T.2
Serrano, L.3
-
17
-
-
0033551492
-
The native state conformational ensemble of the SH3 domain from α-spectrin
-
Sadqi, M., S. Casares, E. Freire. 1999. The native state conformational ensemble of the SH3 domain from α-spectrin. Biochemistry. 38:8899-8906.
-
(1999)
Biochemistry.
, vol.38
, pp. 8899-8906
-
-
Sadqi, M.1
Casares, S.2
Freire, E.3
-
18
-
-
35448930794
-
Molecular dynamics simulations from putative transition states of a-spectrin SH3 domain
-
Periole, X., M. Vendruscolo, and A. E. Mark. 2007. Molecular dynamics simulations from putative transition states of a-spectrin SH3 domain. Proteins. 69:536-550.
-
(2007)
Proteins.
, vol.69
, pp. 536-550
-
-
Periole, X.1
Vendruscolo, M.2
Mark, A.E.3
-
19
-
-
30744477442
-
A single mutation induces amyloid aggregation in the a-spectrin SH3 domain: Analysis of the early stages of fibril formation
-
Morel, B., S. Casares, and F. Conejero-Lara. 2006. A single mutation induces amyloid aggregation in the a-spectrin SH3 domain: analysis of the early stages of fibril formation. J. Mol. Biol. 356:453-468.
-
(2006)
J. Mol. Biol.
, vol.356
, pp. 453-468
-
-
Morel, B.1
Casares, S.2
Conejero-Lara, F.3
-
20
-
-
59849130063
-
A single mutation in an SH3 domain increases amyloid aggregation by accelerating nucleation, but not by destabilizing thermodynamically the native state
-
Varela, L., B. Morel, F. Conejero-Lara. 2009. A single mutation in an SH3 domain increases amyloid aggregation by accelerating nucleation, but not by destabilizing thermodynamically the native state. FEBS Lett. 583:801-806.
-
(2009)
FEBS Lett.
, vol.583
, pp. 801-806
-
-
Varela, L.1
Morel, B.2
Conejero-Lara, F.3
-
21
-
-
0032849874
-
Quantification of 3-sheet amyloid fibril structures with thioflavin T
-
LeVine, 3rd, H. 1999. Quantification of 3-sheet amyloid fibril structures with thioflavin T. Methods Enzymol. 309:274-284.
-
(1999)
Methods Enzymol.
, vol.309
, pp. 274-284
-
-
Levine Iii, H.1
-
22
-
-
0042467550
-
Rationalization of the effects of mutations on peptide and protein aggregation rates
-
Chiti, F., M. Stefani, C. M. Dobson. 2003. Rationalization of the effects of mutations on peptide and protein aggregation rates. Nature. 424:805-808.
-
(2003)
Nature.
, vol.424
, pp. 805-808
-
-
Chiti, F.1
Stefani, M.2
Dobson, C.M.3
-
23
-
-
13444269021
-
Critical balance of electrostatic and hydrophobic interactions is required for 3 2-microglobulin amyloid fibril growth and stability
-
Raman, B., E. Chatani, Y. Goto. 2005. Critical balance of electrostatic and hydrophobic interactions is required for 3 2-microglobulin amyloid fibril growth and stability. Biochemistry. 44:1288-1299.
-
(2005)
Biochemistry.
, vol.44
, pp. 1288-1299
-
-
Raman, B.1
Chatani, E.2
Goto, Y.3
-
24
-
-
77949781943
-
The thermodynamic stability of amyloid fibrils studied by differential scanning calorimetry
-
Morel, B., L. Varela, and F. Conejero-Lara. 2010. The thermodynamic stability of amyloid fibrils studied by differential scanning calorimetry. J. Phys. Chem. B. 114:4010-4019.
-
(2010)
J. Phys. Chem. B.
, vol.114
, pp. 4010-4019
-
-
Morel, B.1
Varela, L.2
Conejero-Lara, F.3
-
25
-
-
33749832945
-
Elucidating amyloid 3-protein folding and assembly: A multidisciplinary approach
-
Teplow, D. B., N. D. Lazo, H. E. Stanley. 2006. Elucidating amyloid 3-protein folding and assembly: a multidisciplinary approach. Acc. Chem. Res. 39:635-645.
-
(2006)
Acc. Chem. Res.
, vol.39
, pp. 635-645
-
-
Teplow, D.B.1
Lazo, N.D.2
Stanley, H.E.3
-
26
-
-
33644527256
-
Characterization ofoligomers during a-synuclein aggregation using intrinsic tryptophan fluorescence
-
Dusa, A., J. Kaylor, A. L. Fink. 2006. Characterization ofoligomers during a-synuclein aggregation using intrinsic tryptophan fluorescence. Biochemistry. 45:2752-2760.
-
(2006)
Biochemistry.
, vol.45
, pp. 2752-2760
-
-
Dusa, A.1
Kaylor, J.2
Fink, A.L.3
-
27
-
-
51349098137
-
Evidence for stepwise formation of amyloid fibrils by the mouse prion protein
-
Jain, S., and J. B. Udgaonkar. 2008. Evidence for stepwise formation of amyloid fibrils by the mouse prion protein. J. Mol. Biol. 382:1228-1241.
-
(2008)
J. Mol. Biol.
, vol.382
, pp. 1228-1241
-
-
Jain, S.1
Udgaonkar, J.B.2
-
28
-
-
33750294048
-
Direct observation of oligomeric species formed in the early stages of amyloid fibril formation using electrospray ionisation mass spectrometry
-
Smith, A. M., T. R. Jahn, S. E. Radford. 2006. Direct observation of oligomeric species formed in the early stages of amyloid fibril formation using electrospray ionisation mass spectrometry. J. Mol. Biol. 364:9-19.
-
(2006)
J. Mol. Biol.
, vol.364
, pp. 9-19
-
-
Smith, A.M.1
Jahn, T.R.2
Radford, S.E.3
-
29
-
-
23444447864
-
Evidence for a mechanism of amyloid formation involving molecular reorganisation within native-like precursor aggregates
-
Plakoutsi, G., F. Bemporad, F. Chiti. 2005. Evidence for a mechanism of amyloid formation involving molecular reorganisation within native-like precursor aggregates. J. Mol. Biol. 351:910-922.
-
(2005)
J. Mol. Biol.
, vol.351
, pp. 910-922
-
-
Plakoutsi, G.1
Bemporad, F.2
Chiti, F.3
-
30
-
-
0037020259
-
Kinetic studies of amyloid β-protein fibril assembly. Differential effects of α-helix stabilization
-
Fezoui, Y., and D. B. Teplow. 2002. Kinetic studies of amyloid β-protein fibril assembly. Differential effects of α-helix stabilization. J. Biol. Chem. 277:36948-36954.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 36948-36954
-
-
Fezoui, Y.1
Teplow, D.B.2
-
31
-
-
33847769109
-
Mechanism of formation of amyloid protofibrils of barstar from soluble oligomers: Evidence for multiple steps and lateral association coupled to conformational conversion
-
Kumar, S., S. K. Mohanty, and J. B. Udgaonkar. 2007. Mechanism of formation of amyloid protofibrils of barstar from soluble oligomers: evidence for multiple steps and lateral association coupled to conformational conversion. J. Mol. Biol. 367:1186-1204.
-
(2007)
J. Mol. Biol.
, vol.367
, pp. 1186-1204
-
-
Kumar, S.1
Mohanty, S.K.2
Udgaonkar, J.B.3
-
32
-
-
1542533563
-
Role of protein-water interactions and electrostatics in a-synuclein fibril formation
-
Munishkina, L. A., J. Henriques, A. L. Fink. 2004. Role of protein-water interactions and electrostatics in a-synuclein fibril formation. Biochemistry. 43:3289-3300.
-
(2004)
Biochemistry.
, vol.43
, pp. 3289-3300
-
-
Munishkina, L.A.1
Henriques, J.2
Fink, A.L.3
-
33
-
-
35148899284
-
Effect of different salt ions on the propensity of aggregation and on the structure of Alzheimer's A[β](1-40) amyloid fibrils
-
Klement, K., K. Wieligmann , M. Fändrich. 2007. Effect of different salt ions on the propensity of aggregation and on the structure of Alzheimer's A[β](1-40) amyloid fibrils. J. Mol. Biol. 373:1321-1333.
-
(2007)
J. Mol. Biol.
, vol.373
, pp. 1321-1333
-
-
Klement, K.1
Wieligmann, K.2
Fändrich, M.3
-
34
-
-
33744937549
-
Sulfates dramatically stabilize a salt-dependent type of glucagon fibrils
-
Pedersen, J. S., J. M. Flink, D. E. Otzen. 2006. Sulfates dramatically stabilize a salt-dependent type of glucagon fibrils. Biophys. J. 90:4181-4194.
-
(2006)
Biophys. J.
, vol.90
, pp. 4181-4194
-
-
Pedersen, J.S.1
Flink, J.M.2
Otzen, D.E.3
-
36
-
-
33846283349
-
Kinetics of different processes in human insulin amyloid formation
-
Mauro, M., E. F. Craparo, P. L. San Biagio. 2007. Kinetics of different processes in human insulin amyloid formation. J. Mol. Biol. 366:258-274.
-
(2007)
J. Mol. Biol.
, vol.366
, pp. 258-274
-
-
Mauro, M.1
Craparo, E.F.2
San Biagio, P.L.3
-
37
-
-
0035815664
-
Evidence for a partially folded intermediate in a-synuclein fibril formation
-
Uversky, V. N., J. Li, and A. L. Fink. 2001. Evidence for a partially folded intermediate in a-synuclein fibril formation. J. Biol. Chem. 276:10737-10744.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 10737-10744
-
-
Uversky, V.N.1
Li, J.2
Fink, A.L.3
-
38
-
-
19444384541
-
Desolvation is a likely origin of robust enthalpic barriers to protein folding
-
Liu, Z., and H. S. Chan. 2005. Desolvation is a likely origin of robust enthalpic barriers to protein folding. J. Mol. Biol. 349:872-889.
-
(2005)
J. Mol. Biol.
, vol.349
, pp. 872-889
-
-
Liu, Z.1
Chan, H.S.2
-
39
-
-
33751408436
-
Interactions between macromolecules and ions: The Hofmeister series
-
Zhang, Y., and P. S. Cremer. 2006. Interactions between macromolecules and ions: the Hofmeister series. Curr. Opin. Chem. Biol. 10:658-663.
-
(2006)
Curr. Opin. Chem. Biol.
, vol.10
, pp. 658-663
-
-
Zhang, Y.1
Cremer, P.S.2
-
40
-
-
0036377156
-
Amyloid-fibril formation. Proposed mechanisms and relevance to conformational disease
-
Zerovnik, E. 2002. Amyloid-fibril formation. Proposed mechanisms and relevance to conformational disease. Eur. J. Biochem. 269:3362-3371.
-
(2002)
Eur. J. Biochem.
, vol.269
, pp. 3362-3371
-
-
Zerovnik, E.1
-
41
-
-
0344944630
-
Protein aggregation and aggregate toxicity: New insights into protein folding, misfolding diseases and biological evolution
-
Stefani, M., and C. M. Dobson. 2003. Protein aggregation and aggregate toxicity: new insights into protein folding, misfolding diseases and biological evolution. J. Mol. Med. 81:678-699.
-
(2003)
J. Mol. Med.
, vol.81
, pp. 678-699
-
-
Stefani, M.1
Dobson, C.M.2
-
42
-
-
34948850365
-
Aquaporin 1 and aquaporin 4 overexpression in bovine spongiform encephalopathy in a transgenic murine model and in cattle field cases
-
Costa, C., R. Tortosa, M. Pumarola. 2007. Aquaporin 1 and aquaporin 4 overexpression in bovine spongiform encephalopathy in a transgenic murine model and in cattle field cases. Brain Res. 1175:96-106.
-
(2007)
Brain Res.
, vol.1175
, pp. 96-106
-
-
Costa, C.1
Tortosa, R.2
Pumarola, M.3
-
43
-
-
49049086061
-
Close association of water channel AQP1 with amyloid-β deposition in Alzheimer disease brains
-
Misawa, T., K. Arima, J. Satoh. 2008. Close association of water channel AQP1 with amyloid-β deposition in Alzheimer disease brains. Acta Neuropathol. 116:247-260.
-
(2008)
Acta Neuropathol.
, vol.116
, pp. 247-260
-
-
Misawa, T.1
Arima, K.2
Satoh, J.3
-
44
-
-
27744437192
-
From chance to frequent encounters: Origins of β2-microglobulin fibrillogenesis
-
Eakin, C. M., and A. D. Miranker. 2005. From chance to frequent encounters: origins of β2-microglobulin fibrillogenesis. Biochim. Biophys. Acta. 1753:92-99.
-
(2005)
Biochim. Biophys. Acta.
, vol.1753
, pp. 92-99
-
-
Eakin, C.M.1
Miranker, A.D.2
-
45
-
-
44049093682
-
Different hydration changes accompanying copper and zinc binding to amyloid β-peptide: Water contribution to metal binding
-
Yu, H. J., J. S. Ren, and X. G. Qu. 2008. Different hydration changes accompanying copper and zinc binding to amyloid β-peptide: water contribution to metal binding. ChemBioChem. 9:879-882.
-
(2008)
ChemBioChem.
, vol.9
, pp. 879-882
-
-
Yu, H.J.1
Ren, J.S.2
Qu, X.G.3
-
46
-
-
70349272854
-
Two disaccharides and trimethylamine N-oxide affect Aβ aggregation differently, but all attenuate oligomer-induced membrane permeability
-
Qi, W., A. M. Zhang, E. J. Fernandez. 2009. Two disaccharides and trimethylamine N-oxide affect Aβ aggregation differently, but all attenuate oligomer-induced membrane permeability. Biochemistry. 48:8908-8919.
-
(2009)
Biochemistry.
, vol.48
, pp. 8908-8919
-
-
Qi, W.1
Zhang, A.M.2
Fernandez, E.J.3
|