Role of rare variants in undetermined multiple adenomatous polyposis and early-onset colorectal cancer

Journal of Human Genetics

Volumn 57, Issue 11, 2012, Pages 709-716

  Lefevre, Jérémie H ^a,b,c   Bonilla, Carolina ^a,b,f   Colas, Chrystelle ^c,d   Winney, Bruce ^a   Johnstone, Elaine ^e   Tonks, Susan ^a   Day, Tammy ^a   Hutnik, Katarzyna ^a   Boumertit, Abdelhamid ^a   Soubrier, Florent ^d   Midgley, Rachel ^a   Kerr, David ^e   Parc, Yann ^c   Bodmer, Walter F ^a,b  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c HÔPITAL SAINT ANTOINE   (France)

^d PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^e UNIVERSITY OF OXFORD   (United Kingdom)

^f UNIVERSITY OF BRISTOL   (United Kingdom)

Author keywords

adenomatous polyposis; APC; colorectal neoplasia; rare variant

Indexed keywords

ADENOMATOUS POLYP; ADULT; ARTICLE; CANCER SUSCEPTIBILITY; COLORECTAL CANCER; CONTROLLED STUDY; EARLY CANCER; FEMALE; GENE; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC VARIABILITY; HUMAN; MAJOR CLINICAL STUDY; MALE; RISK FACTOR;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADENOMA; ADENOMATOUS POLYPOSIS COLI; ADULT; AGE OF ONSET; BETA CATENIN; BRCA2 PROTEIN; CASE-CONTROL STUDIES; COLORECTAL NEOPLASMS; COMPUTER SIMULATION; DNA REPAIR ENZYMES; EXODEOXYRIBONUCLEASES; FRANCE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENETIC VARIATION; GREAT BRITAIN; HUMANS; MIDDLE AGED; NUCLEAR PROTEINS; ODDS RATIO;

EID: 84870256471     PISSN: 14345161     EISSN: 1435232X     Source Type: Journal    
DOI: 10.1038/jhg.2012.99     Document Type: Article

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