The APC variants I1307K and E1317Q are associated with colorectal tumors, but not always with a family history

Proceedings of the National Academy of Sciences of the United States of America

Volumn 95, Issue 18, 1998, Pages 10722-10727

  Frayling, Ian M ^a   Beck, Nicholas E ^d   Ilyas, Mohammad ^d   Dove Edwin, Isis ^a   Goodman, Peter ^d   Pack, Kevin ^a   Bell, Jennifer A ^b   Williams, Christopher B ^c   Hodgson, Shirley V ^e   Thomas, Huw J W ^a   Talbot, Ian C ^a   Bodmer, Walter F ^d   Tomlinson, Ian P M ^a,f  

^a IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^b Kennedy Galton Centre   (United Kingdom)

^c Wolfson Unit for Endoscopy   (United Kingdom)

^d JOHN RADCLIFFE HOSPITAL   (United Kingdom)

^e GUY S HOSPITAL   (United Kingdom)

^f UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CANCER RISK; CANCER SUSCEPTIBILITY; CLINICAL TRIAL; COLORECTAL CANCER; COLORECTAL TUMOR; CONTROLLED STUDY; FAMILIAL POLYPOSIS; FAMILY HISTORY; FEMALE; GENE LOCATION; GENE MUTATION; GENETIC ANALYSIS; GENETIC PREDISPOSITION; GENETIC VARIABILITY; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; MISSENSE MUTATION; PRIORITY JOURNAL;

ADULT; AGED; BASE SEQUENCE; COLORECTAL NEOPLASMS; DNA PRIMERS; FEMALE; GENES, APC; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MALE; MIDDLE AGED; MUTATION; PEDIGREE; POLYMERASE CHAIN REACTION; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL;

EID: 13144305057     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.95.18.10722     Document Type: Article

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